What makes a good weight–related study in PCORnet

• Patient centered comparative effectiveness– Patient/stakeholder engagement throughout– Uses PCORnet infrastructure

• Multiple CDRNs, PPRNS• Built from common data model (CDM)• Multiple data sources, e.g., EMR, claims, patient reported outcomes

– Low frequency exposure and/or outcomes• Other reasons for large numbers, e.g., subgroup analysis

– Practice or other geographic variation– Diversity– Natural experiments

• Implementation and dissemination

– Simulation of best practices– Individual and cluster randomized control trials (RCTs)

• Etiology/prediction?

What makes a good weight–related study in PCORnet

• Possible cross-cutting rubric for identifying studies– Observational studies• Use existing data• Linkages (family members)• Patient-reported data• Biorepository

– Interventions