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What’sNext
2 0 1 4 A n n u a l R e p o r t
3. Letter from CEO Steven M. Altschuler, M.D.
4. After ‘No Options Left’Stunning Success Rates in Study of T-cell Therapy for Relapsed Leukemia
Multidimensional MedicinePioneering Experts Use 3-D Printing to Move Treatments into the Next Dimension
12. Tackling Youth Violence Head-onCHOP Initiative Is Fast Becoming a National Model for Violence Prevention
Ahead of the PackCHOP’s Focus on Concussion Spans Diagnosis, Treatment and Research
20. Born of a BreakthroughCHOP Creates a For-profit Company to Advance Gene Therapy, Fund Research
22. Expert, Urgent Care
Twilight Transformation Gives Families New Choices for After-hours Service
Shared WatchCHOP’s Good Catch Program Helps Connect Every Employee to Patient Safety
30. A Year of GenerosityDonors Push CHOP Philanthropy to Multiple Records in 2014
32. Shining StarsRecognizing Nine Clinicians and Scientists for Outstanding Achievements in 2014
S T O R I E S
TABLE OF CONTENTS
N U M B E R S
L E A D E R S H I P
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38. CHOP Leadership
39. Board of Trustees
40. Endowed Chair Holders
44. Financial Information and Hospital, Research and Foundation Statistics
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3INNOVATING, LEADING: CHOP IS ‘WHAT’S NEXT’
Dear Friends:
At The Children’s Hospital of Philadelphia, we are dedicated to offering the
world’s best pediatric medical care today — but that isn’t enough. We’re working
every day to push the envelope and redefine what is possible in medicine,
pioneering new, life-changing treatments for diseases that affect children.
In that spirit, we chose the theme of the 2014 Annual Report, What’s Next, to
give you a glimpse into the future we are creating for children in our community
and around the world. In the report, you’ll learn about a far-reaching CHOP
initiative to prevent bullying and youth violence, a new startup venture to
advance gene therapy for childhood diseases, innovative new uses for 3-D
printing, an update on the breakthrough cancer therapy that has gained
worldwide attention and much more. We’ll also introduce you to some of the
innovators whose work you are sure to hear about for years to come.
The research and care milestones we’ve accomplished in 2014 will continue to
improve healthcare for future generations of children. Whether you’re part of the
CHOP community as a patient family, employee, donor or someone who simply
cares about children’s health, we thank you for joining with us to give every child
the best possible start in life.
Steven M. Altschuler, M.D.
Chief Executive Officer
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STUNNING SUCCESS RATES IN STUDY OF T-CELL THERAPY FOR RELAPSED LEUKEMIA
AFTER ‘NO OPTIONS LEFT’ — REMISSION
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On April 16, 2013, Dana and Chris Lee sat bedside at The Children’s Hospital
of Philadelphia as their last best hope began to filter through the IV in their
9-year-old’s arm.
Tori had been diagnosed with acute lymphoblastic leukemia (ALL), the most
common childhood cancer, as a kindergartner. Since then, she’d relapsed twice.
She had never experienced a full year of school. Friends she’d made in the hospital
had died. “The pain and suffering of so many families is always around us in this
world,” Dana Lee says, “and we were so close to that point of a parent’s worst
nightmare.”
Tori is one of 25 children and five adults who traveled to Philadelphia between
April 2012 and February 2014 to take part in a study that now has the world’s
attention. They came to CHOP and the University of Pennsylvania from around
the country, with cancer at a stage previously considered incurable.
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Immune Cells AttackThe patients received cells, called CTL019, created from their own immune systems. Scientists re-engineered T cells, the workhorses of the immune system, to recognize and attack an invader that normally flies under their radar: cancer cells.
The latest results, published in October 2014 in The New England Journal of Medicine, are unprecedented: Ninety percent were in complete remission after one month and 67 percent remained in complete remission after six months. The first child to take part has been in remission for more than two years. By comparison, remission rates for the three drugs most recently approved for relapsed ALL are reported at less than 25 percent.
“The patients who participated in these trials had relapsed as many as four times, including 60 percent whose cancers came back even after stem-cell transplants. Their cancers were so aggressive, they had no treatment options left,” says Stephan Grupp, M.D., Ph.D., the oncologist who leads the study at CHOP. “But what we are most excited about is that a number of these children have remained in remission with no further therapy for up to 2½ years. These durable
responses we have observed with CTL019 therapy are unprecedented.”
Scientists have been trying to engineer T cells to attack cancer cells for more than 20 years, but had difficulty creating cells that would proliferate (multiply) and persist in the body. The cells in the Penn-CHOP study demonstrate a high level of proliferation and persistence. It appears that high-level proliferation can lead to high response rates, while persistence leaves anticancer T cells “on the hunt” and can keep kids in remission.
FDA-designated BreakthroughIn July, the U.S. Food and Drug Administration designated CTL019 for relapsed ALL a “breakthrough therapy.” It is the first time a personalized cellular therapy for cancer has received this designation, which can help speed the path to approval as a treatment. CTL019 studies for relapsed leukemia are now open at other children’s hospitals, with CHOP as the lead center, and there are plans to extend the research to other types of cancer, including relapsed neuroblastoma. Pharmaceutical giant Novartis has licensed rights to the therapy.
For some families who took part in this groundbreaking study, hopes were not realized: There have been deaths. These children and adults contributed to an effort that will save many others.
Dana Lee thinks often of those children who didn’t make it. “I look at Tori and I know that every day is such a gift,” she says.
Last year Tori finished a full year of school with no interruption. She started fifth grade this fall. “Tori is running on the beach,” her mom says. “She’s fearless on the diving board. She has playdates. She is a little girl smiling and doing kid stuff. T-cell therapy gave us this.” n
Each year an estimated 10,450 children under the age of 15 will be diagnosed with cancer. That’s about 29 kids every 24 hours.
Opposite: Tori at home in New Jersey with her parents, Chris and Dana.
kids
Tori at a follow-up visit with Stephan Grupp, M.D., Ph.D., 1½ years after she received T-cell therapy. Grupp is director of translational research for the Center for Childhood Cancer Research at CHOP.
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I look at Tori and I know that every day is such a gift.”
“– Dana Lee
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Multidimensional Medicine
NEXT DIMENSIONPIONEERING EXPERTS USE 3-D PRINTING TO MOVE TREATMENTS INTO THE
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In a cramped room on the ninth floor of CHOP’s Main
Building sits a machine that’s reshaping the future of healthcare — one 3-D-printed heart at a time.
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Most airway devices, like this one used by anesthesiologist Jorge Galvez, M.D., are designed for adults. With the help of a 3-D printer, Galvez hopes to change the way pediatric medical devices are created.
Only 16 percent of approved, high-risk
medical devices were studied in children younger than
18 years old. Most devices are developed for adults, then
later approved for children, despite a lack of evidence they are safe and effective in kids.
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On a late summer morning last year, this machine — the Objet500 Connex3® 3-D printer — was being prepped to build a three-dimensional model of a 3-year-old’s heart. A few days later, the child’s surgeon used the anatomically correct model of his heart to prepare for the complex surgery he needed to survive.
3-D printing any object you can imagine, let alone a child’s heart, may seem like the stuff of science fiction. But it has quickly become a reality here at CHOP.
How Does 3-D Printing Work?Think of an inkjet printer: Software on your computer sends data to the printer, which then injects tiny droplets of ink onto paper.
With 3-D printing, you first create a digital, 3-D model. The computer’s software sends the model’s data in cross sections to the printer. Instead of ink, the 3-D printer injects drops of liquid plastic onto the printing surface. Ultraviolet light then converts the liquid polymer to a solid layer before more plastic is injected on top, building the finished product layer by layer.
With 3-D printing, if you can dream it, you can probably design and build it. And the experts at CHOP are certainly not lacking for ideas on how to use the Hospital’s printer. Here are just two of the pioneering projects currently underway.
Planning for Complex Heart SurgeriesWhile tremendous strides have been made in treating children with complex congenital heart defects — many right here at CHOP — there’s always room for improvement. “All of the advanced imaging technology we have can facilitate the way surgeries are performed, but it still has its limitations,” says cardiologist Yoav Dori, M.D.
Instead of looking at a flat MRI to determine the best way to perform a surgical repair, Dori and cardiologist Mark Fogel, M.D., director of Cardiac Magnetic Resonance Imaging, can use the Connex printer to create an exact model of a heart, defects and all, in a material that can be cut into, patched and sewn by a surgeon.
The theory that 3-D-printed hearts can help improve surgical outcomes is the subject of a recently initiated multicenter trial. The trial is the first of its kind to put the medical benefits of 3-D printing to the test.
Customized Airway Devices for KidsWhen a patient is under anesthesia, the muscles in the neck that keep the airway open become loose. Anesthesiologists like Jorge Galvez, M.D., use airway devices to keep the area open. Unfortunately, airway devices — like most medical devices — are designed for adults with normal anatomy, not children.
“A lot of kids who are difficult to intubate and need an airway device are not going to have normal anatomy,” says Galvez. With the help of a 3-D printer, though, Galvez and mechanical engineering students at the University of Pennsylvania were able to manufacture a customizable airway device.
The Penn students designed a software program into which doctors can input measurements taken from a child. In just a few hours, a 3-D printer can produce an airway device that’s designed specifically for the patient’s size and anatomy.
These 3-D printed airway devices have not yet been tested in people, and there are a few regulatory hurdles to manage before they can be used in the real world. Still, to say Galvez is excited about the potential uses for 3-D printing is an understatement. “Instead of continuing to work around the challenges of devices designed for adults,” he says, “we now have the power to create things made just for kids. Just think of all the possibilities!” n
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Cardiologists Mark Fogel, M.D., and Yoav Dori, M.D., are using this massive 3-D printer to create replicas of their patients’ hearts. “Anyone can see that 3-D printing is cool,” says Fogel, “but we’re using it to push the medical field forward,” which is a lot more than just cool.
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A CHOP INITIATIVE IS FAST BECOMING A NATIONAL MODEL FOR HOSPITAL-LED YOUTH VIOLENCE PREVENTION
A few months into sixth grade, Chedaya
got a brand-new pair of sneakers. She loved them.
But so did a girl in her class, who suddenly started
bullying her about them.
Chedaya had never been in a fight. But when the girl
challenged her over the shoes, she felt pressured to
stand up for herself.
“I was scared, but I didn’t want to look scared,” Chedaya says.
TACKLINGYOUTH VIOLENCE HEAD-ON
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13In sixth grade, Chedaya was bullied over the sneakers she is shown holding here. The bullying turned violent, landing Chedaya in CHOP’s Emergency Department, where she was connected to the Hospital’s Violence Intervention Program and set on the path to recovery.
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She met the girl in a park near school, where she was punched in the face, stomach and legs, and her braids were pulled out. Another student filmed the fight and posted it on Instagram — an online social networking site — for all to see.
Her mom arrived to find Chedaya physically and emotionally shaken. She took her to CHOP’s Emergency Department (ED), just a short drive away. In many other emergency rooms, Chedaya likely would have been treated for her physical wounds and sent on her way. But in CHOP’s ED, while a medical team cared for her physical symptoms, a social worker also tended to her emotional ones, connecting the family with CHOP’s Violence Intervention Program (VIP).
Breaking the Cycle Aggressive behavior is a common issue facing today’s youth, involving almost one-third of adolescents. VIP capitalizes on the teachable moment for youth ages 8 through 18 who seek medical care in the ED after a violent event, in an effort to reduce re-injury and retaliation. It’s just one aspect of CHOP’s Violence Prevention Initiative, a Hospital-wide effort to interrupt the cycle of youth violence, which also includes programs in schools and the community. With a multidisciplinary team made up of some of the nation’s foremost experts in violence intervention, anti-bullying methods and trauma-informed care, CHOP is uniquely positioned to take on this issue and is fast becoming a national model for hospital-led youth violence prevention.
“As an institution that exists to promote the health and well-being of children and as the nation’s leading pediatric hospital, it is our responsibility to find ways to prevent this epidemic from spreading,” said Steven M. Altschuler, M.D., CHOP CEO, at the launch of the initiative last year. “We hope to find ways to stop the violence that is taking such a toll on children and families in our community.”
For its part, VIP provides emotional and social support for youth and their families through intensive case management services, helping youth exposed to violence deal with their emotions and reactions to difficult social situations, and increasing self-esteem and leadership skills. VIP applies a trauma-informed approach that considers previous traumatic experiences families bring with them to this recovery process, which can impact how they respond to supportive efforts.
“Violence is cyclical,” says CHOP violence prevention specialist Laura Vega, M.S.W., L.S.W. “It is our goal to interrupt that cycle so that healing can begin.”
On the Mend The fight left Chedaya feeling a confusing mix of emotions, from sad and fearful to angry and vengeful. Vega connected her with an individual therapist, as well as a group therapy program with other adolescent girls who had been through similar experiences.
“I started expressing my feelings more,” says the soft-spoken teen. “And the other girls in the group gave me tips and advice, because they were all older than me. They talked to me about the other road to go on … that I don’t have to prove anything.”
Chedaya recently finished writing a book with her therapist, with a chapter that details the experience, and is now at a Mastery Charter School in Philadelphia, where she has made new friends and plans to try dance and cheerleading for the first time.
“I’m happy I got connected to VIP. They helped me a lot,” she says. “I think it will help other kids that are going through what I went through.” n
Left: CHOP violence prevention specialist Laura Vega, M.S.W., L.S.W., and Chedaya’s mom, Catina, (pictured here with Chedaya) helped her overcome the bullying and violence she experienced at school. Opposite: Now at a new school, Chedaya has made new friends and has big plans for a bright future.
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1 in 4 kids is bullied sometime during adolescence.– National Center for Education and Bureau of Justice statistic
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16 Daniel, 8, used swimming and yoga for therapy and exercise during the year it took for him to heal from a concussion suffered in a car accident.
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AHEAD OF THE PACK CHOP’S FOCUS ON CONCUSSION SPANS DIAGNOSIS, TREATMENT AND RESEARCH
One minute, 7-year-old Daniel Wanetick was buckled safely in his booster seat
in the back seat of his dad’s car when it was stopped at a light; the next minute,
BANG! The car was rear-ended, sending the Waneticks’ vehicle smashing into
the car in front of it.
Initially, no one appeared to be injured because there was no visible trauma, not
even a cut. However, when Daniel got home, he said his head hurt. He still had
a headache the next day, so his mother, Neomi Barazani-Wanetick, took him to
their local pediatrician.
“The doctor told us there was nothing abnormal, to continue on as usual,”
Neomi recalls. Daniel went about his typical routine — school, playdates, soccer,
synagogue — but the headaches continued. There were changes in his behavior,
too. Normally a happy-go-lucky kid, Daniel burst into tears over little things.
“He would tell me, ‘I’m just sad,’” Neomi says.
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Days, then weeks, went by, with no improvement — in fact, things got worse. Daniel started to wobble when he walked. It was then Neomi requested a referral and was told: Take him to the Minds Matter Concussion Program at The Children’s Hospital of Philadelphia, one of the most comprehensive concussion programs in the world.
Half of Concussions Aren’t Sports RelatedCHOP’s Christina Master, M.D., F.A.A.P., C.A.Q.S.M., who co-leads Minds Matter, diagnosed Daniel with concussion. “People don’t recognize that motor vehicle accidents can cause a concussion,” Master says. “They think you have to be hit in the head, but all you need is for the brain to shake inside the skull. Whiplash from a crash is a huge unrecognized cause of concussion.” In fact, half of all concussions stem from non-sports injuries.
Younger children can be tricky to diagnose because they have trouble articulating their symptoms, and the typical mental symptoms seen in teenagers and adults, such as difficulty concentrating or remembering and feeling “foggy,” slow or confused, may not occur in younger children as they haven’t developed enough in those areas.
Master ordered total brain rest for Daniel: no school, no TV, no video games, no sports until symptoms improved. After two weeks, he was able to gradually resume activities. She referred him for vestibular therapy to work on balance and eye coordination. Swimming and yoga replaced soccer and baseball. It took a year of treatment before Daniel was released from care.
Spreading the Word“This whole episode taught me that it’s very important to get information about concussions out to doctors and parents,” says Neomi. “Who knows? Maybe his symptoms would not have been so prolonged if we had shut down his activity those first few weeks after the accident.”
Minds Matter is busy addressing both those fronts — concussion education and research.
Its fact-packed website, chop.edu/concussion, lists symptoms and treatments and gives guidelines for reintroducing school and sports after a concussion. All 31 primary care practices in the CHOP Care Network feature at least one Concussion Champion who is specially trained in diagnosing and treating concussion. This gives families a convenient, familiar starting point if they suspect their child has suffered a concussion. Last year about 12,800 patients were treated for concussion by CHOP.
Multilevel ResearchOn the research front, a multilevel effort is striving to examine all aspects of concussion. Using CHOP’s integrated electronic medical record, the Minds Matter team is tracking thousands of patients, their symptoms, treatment and outcomes, allowing the team to verify best practices for recovery. This “registry” of pediatric patients drew the attention of the White House and a Clinical and Translational Science Award (CTSA) grant.
In the lab, researcher Akiva Cohen, Ph.D., received a prestigious MERIT grant from the National Institutes of Health to advance his work using cellular nutrients to repair brain damage. Kristy Arbogast, Ph.D., co-scientific director of CHOP’s Center for Injury Research and Prevention, is working on testing the reliability of off-the-shelf sensors by using a crash dummy head in a helmet outfitted with sensors and subjecting it to consistent g-force hits. Next step: Researchers will determine what force is likely to be “enough” to cause a concussion.
“Most of the concussion data out there concerns high-school-and-older patients with sports-related injuries,” Master says. “At CHOP, we see more kids with concussion than any other institution in the country — covering all ages and all types of injuries. That puts us in a leadership position to determine optimal diagnostic techniques and treatments, no matter how old the patient is. It’s a problem that isn’t going away. We’re ready to do what it takes to help children with concussion.” n
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Minds Matter co-leader Christina Master, M.D., F.A.A.P., C.A.Q.S.M., (left) and CHOP President and COO Madeline Bell were invited to the White House for the Healthy Kids & Safe Sports Concussion Summit in May. Children’s Hospital was singled out for its comprehensive pediatric and adolescent concussion registry, which will guide the development of tools for diagnosing concussion and monitoring recovery.
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Samantha, 11, has hadfour concussions. Afterpassing various tests inthe concussion clinic —including showing shecan walk heel-toe-heel-toedown a line, backwardand forward, eyesclosed and eyes open —Christina Master, M.D.,gave her the all-clear.
On impact, the brain moves inside the skull.
The circuits stretch or break, causing the brain to not
function normally.
concussion?What is a
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CHOP CEO Steven M. Altschuler, M.D., (center) with Katherine High, M.D., scientific co-founder, president and chief scientific officer of Spark Therapeutics, and Jeffrey Marrazzo, M.B.A., M.P.A., Spark’s co-founder and CEO.
BORN OF A BREAKTHROUGHCHOP CREATES A FOR-PROFIT COMPANY TO ADVANCE
GENE THERAPY — AND FUND FURTHER RESEARCH
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The first decade of the 21st century was a time of remarkable progress at The Children’s Hospital of Philadelphia.
Researchers and clinicians had made incredible breakthroughs in vaccines, fetal surgery and cancer treatment — and countless other discoveries were on the horizon. But as the decade drew to a close, Hospital leaders became increasingly concerned about where funding for the next big breakthrough would come from.
So they decided to call on some truly extraordinary resources: their own.
A Bold ConceptIn 2010, CHOP CEO Steven M. Altschuler, M.D., asked Jeffrey Marrazzo, M.B.A., M.P.A., a consultant and entrepreneur with vast experience in the healthcare industry, to identify projects already underway at CHOP that could be commercialized to benefit more patients and, in turn, return funds to the Hospital.
Marrazzo didn’t have to look far. Just a few months later, he came back to Altschuler with a promising candidate: the Center for Cellular and Molecular Therapeutics’ (CCMT) pioneering gene therapy work, which was already showing tremendous promise in treating a rare form of inherited blindness.
After much discussion with Board of Trustees members and Hospital administrators, Altschuler and his team decided that CHOP should create its own for-profit gene therapy company, with CHOP serving initially as its sole equity investor. The Hospital hopes someday to receive a return on this investment, which could then be used to fund additional research at CHOP.
In many ways, this is a logical next step in a long process. At a time when other institutions had turned away from gene therapy, CHOP had assembled a world-class team of gene therapy experts at the CCMT who were handling everything from manufacturing to clinical trials. The arrangement Altschuler and Marrazzo proposed would allow the CCMT team to remain deeply involved in the work and broaden its scope to benefit even more children.
“The gene therapy technology is so important to what we want to do as an institution,” says Altschuler. “I was looking for a way to move it forward that would allow us to further our research with the technology and provide us the best opportunity to integrate that with what we wanted to do clinically.”
A Powerful MissionThe Hospital launched Spark Therapeutics in 2013, with Katherine High, M.D., former director of the CCMT, serving as one of the company’s scientific co-founders and as president and chief scientific officer, and Marrazzo in the role of co-founder and CEO. The blindness therapy, currently in a Phase III clinical trial, recently received breakthrough therapy designation from the U.S. Food and Drug Administration —
and has the potential to be the first approved gene therapy for a genetic disease in the United States. “We’re in a good position to try to bring a product across the finish line and actually be able to help people who are born with a previously untreatable illness,” says High.
At the same time, the work has the potential to help many more children by generating funds to support new research. “It allows CHOP to invest in the next great idea,” says Marrazzo. “The money that was put into a place like the CCMT can be put into the next CCMT.”
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“At CHOP, we do everything that a normal business would do to be successful, but at the end, we don’t give that money to shareholders. We reinvest that money in the community and to improve the health of children.”
– Steven M. Altschuler, M.D. CEO, The Children’s Hospital of Philadelphia
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TWILIGHT TRANSFORMATION GIVES FAMILIES NEW CHOICES FOR AFTER-HOURS SERVICE
Expert, Urgent Care: A World of Difference
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Twice 12-year-old Andrew DiSanto had a fever, but no other symptoms.
Twice it went away. The third time, when he came home from school on
a Friday in March with yet another fever, his mother, Charlene, had an
uncomfortable feeling.
“You don’t get a fever for no reason, especially three times,” she says.
Even though a drugstore blocks from their Collegeville, Pa., home
had a health clinic, Charlene recalled a friend mentioning that The
Children’s Hospital of Philadelphia had opened an Urgent Care Center
in the CHOP Care Network Specialty Care Center in King of Prussia.
On Saturday, she drove Andrew there.
They were quickly ushered into an exam room. A pediatrician
examined Andrew and, with the preliminary diagnosis of community-
acquired pneumonia, ordered a chest X-ray. Read immediately by
CHOP pediatric radiologists, the X-ray showed an
unexpected mass between Andrew’s heart and
lungs. “When he said ‘mass,’ I knew it was cancer.
It was a whirlwind after that,” says Charlene.
Opposite: At 4 p.m. each weekday, part of the CHOP C are Network King of Prussia Specialty Care Center transforms into the Urgent Care Center. Members of the Urgent Care staff, including (from left) Lorie Faber, R.N., B.S.N.; Becky Donahue, R.N., B.S.N.; Amitha Sampath, M.D.; and Meghan Reno, R.N., B.S.N., bring a wealth of experience to the patients they see. Urgent Care is also open on weekends and holidays.
Above: Andrew, now 13, is cancer free after seven months of treatment.
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Best Care an Ambulance Ride AwayAndrew and Charlene went by ambulance to CHOP’s Emergency Department so he could be admitted to the Hospital quickly. By evening, he was on the oncology unit and doctors were working to find out what kind of cancer he had. The final diagnosis: Hodgkin lymphoma, one of the most common, and most curable, childhood cancers.
“If we had waited to go to our pediatrician, it probably would have taken longer to find out he had cancer,” Charlene says. “Urgent Care at King of Prussia made a world of difference for us. CHOP is the best hospital and where we wanted him to be.”
Urgent Care — the newest service from the CHOP Care Network — was Andrew’s entry point into a comprehensive care system that spans more than 50 locations and covers circumstances ranging from well-baby checkups to specialists’ appointments to care for the most complex conditions. Families move seamlessly to the level of care their child requires; all their care providers are connected and have instant electronic access to patients’ medical records.
After getting his first treatment while in the Hospital, Andrew received the rest of his chemotherapy under the watchful eye of his oncologist, Julie Stern, M.D., at the CHOP Specialty Care Center in King of Prussia — the same space that becomes the Urgent Care Center on evenings and weekends. “I learned about Andrew the Monday after he had been to Urgent Care, while he was still an inpatient,” Stern says. “Because Andrew received his treatment at our King of Prussia oncology clinic, it was easier for him to continue with
school and baseball as much as possible, which was so important for his mental health. He had a wonderful attitude.”
Andrew finished his treatment with radiation at the Roberts Proton Therapy Center, across the street from Children’s Hospital. His scans now show no signs of cancer.
Filling the GapThe DiSanto family’s experience is what CHOP envisioned when it expanded into urgent care.
“Our goal is to structure our services to meet the needs of families,” says President and Chief Operating Officer Madeline Bell. “CHOP’s Urgent Care Centers fill the gap between the child’s primary pediatrician and the Emergency Department. They are convenient to our suburban families and, when a child needs to follow up with a specialist, our Urgent Care staff can make those connections.”
Children’s Hospital opened its first Urgent Care Center in July 2013 in the Atlantic County Specialty Care Center in Mays Landing, N.J., and followed with the King of Prussia location in February 2014. In early 2015, the third Urgent Care will open in the Bucks County Specialty Care and Ambulatory Surgery Center in Chalfont, Pa. All locations have X-ray equipment and labs, which can speed diagnoses.
“We opened our Urgent Care Centers because this is what families want: the right level of care, at the right time, right in their communities,” says Amy Lambert, senior vice president, CHOP Care Network. “We have trained pediatricians who know how to care for kids in these situations. They have specific skills around lower-level traumas — suturing, splinting, foreign body removal. The nurses are all CHOP-trained in pediatrics. It allows us to provide a level of expert pediatric care that just isn’t available elsewhere.” n
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Above: Oncologist Julie Stern, M.D., treated Andrew as he was fighting Hodgkin lymphoma. Because King of Prussia is close to his home in Collegeville, his family brought him to the Urgent Care Center there, where his tumor was discovered, and chose the Specialty Care Center for his chemotherapy treatments. The proximity meant as little disruption as possible to Andrew’s school and sports schedule.
Urgent Care’sMost Common Problems
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In spring 2015, the King of Prussia Urgent Care Center — along with Specialty Care, Home Care and the Pediatric Imaging Center — will move to a new home at 550 South Goddard Blvd. The 135,000-square-foot facility (shown here) will also have an Ambulatory Surgery Center. This is just one piece of the building boom in the CHOP Care Network. New, state-of-the-art facilities for the Specialty Care Centers at Chadds Ford, Pa., and Plainsboro, N.J., are slated to open in 2015. A new South Philadelphia Primary Care practice is also underway, in partnership with the City of Philadelphia, and will provide healthcare, literacy and recreational services in one location for South Philadelphia children and families.
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Ezriel Kahan, 3, was kept safe from potential harm thanks in part to careful observation and prompt action on the part of radiologic technologist Sonia Santos.
27
The object was about an inch long,
slightly curved and made of metal.
Radiologic technologist
Sonia Santos couldn’t be sure
what she was looking at, but she
knew it didn’t belong in the
abdomen of a 3-year-old child.
SHARED WATCHCHOP’S GOOD CATCH PROGRAM HELPS CONNECT EVERY EMPLOYEE TO PATIENT SAFETY
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The metal hair clip Ezriel Kahan had swallowed at home, seen here on X-ray, could have caused serious injury had he undergone his scheduled MRI.
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Amy Ford, an Environmental Services employee, was honored with a Good Catch Award for interrupting
patient rounds to alert the medical team to a potential safety issue. “Sometimes we don’t view ourselves as an
important part of the team,” Ford says. “But we are.”
29
Santos had just performed an X-ray on Ezriel Kahan, a patient who would soon have open heart surgery at CHOP’s Cardiac Center. It was a busy day in Radiology, with many patients waiting for studies. In some other hospitals, a radiologic technologist might have passed the films along, allowing physicians to discover the shape and decide what to do.
Santos, who had completed CHOP’s safety behaviors training, was empowered to take action. She looked at the images again, checked carefully to make sure the object wasn’t somewhere on the outside of Ezriel’s clothing, then alerted radiologist David Mong, M.D., and cardiologist Chitra Ravishankar, M.D., of her findings. The next day a team of physicians surgically removed a metal hair clip from Ezriel’s stomach. Unbeknownst to his parents, the little boy had managed to remove the clip from his own hair, worn long at the time, and had swallowed it.
Santos’ prompt action averted a potential disaster: Following his X-ray, Ezriel had been scheduled for a cardiac MRI. Any metal in or on his body would have been attracted with incredible force by the machine’s powerful magnet. The result could have been serious injury or cardiac arrest.
Soon thereafter, Santos was surprised to learn that she had received a highly visible honor: the Hospital’s Good Catch Award. Instituted in 2012, the Good Catch program allows employees to recognize a colleague or themselves — no matter what their job — for an action that helped prevent harm.
“Good Catch helps connect CHOP’s safety efforts to employees in every role throughout the institution,” says Jeanette Teets, M.S.N., R.N., director of Patient Safety. “It’s an especially powerful way to engage employees who are not providing direct clinical care. They may see something, but hesitate to get involved.”
In the last year, the Good Catch program has received 580 nominations from 80 areas of the Main Building and CHOP Care Network, many from clinical staff, but also spanning disciplines as diverse as Environmental Services, Security, Food Service and Music Therapy. The program is just one of the ways CHOP is weaving a culture of safety throughout the entire fabric of the institution.
Safer All OverJan Boswinkel, M.D., vice president of Medical Operations and chief safety officer, looks Hospital-wide for ways to build systems that prevent errors. And many of the best come from front-line staff. “High-reliability organizations go where the expertise is to find new ideas,” he says. “For systems to work, they not only require collaboration across disciplines, they need to be owned at the local level.”
The Office of Clinical Quality Improvement, led by Ron Keren, M.D., M.P.H., is creating and measuring the impact of clinical pathways — protocols that standardize the way care is delivered for various diagnoses, greatly reducing the likelihood of medical decision-making errors.
The Medication Safety team, led by Sean O’Neill, Pharm.D., has implemented bar coding among its efforts to ensure safety in an area whose volume and complexity could leave it vulnerable to mistakes.
More than 5,000 clinical staff have completed safety behavior training, aimed at improving communication skills and overcoming cognitive bias — that is, reaching conclusions based not on what they observe, but on what they’ve experienced before.
Looking beyond its own walls, CHOP is part of Children’s Hospitals’ Solutions for Patient Safety, a national
collaborative of more than 80 pediatric hospitals that employ the “All Teach, All Learn” philosophy. As members of their own Patient Safety Organization, these pediatric hospitals find a protected environment where they are able to share safety events and collectively learn from them.
The Right Thing to DoFor Sonia Santos, “It was nice to be recognized,” she says, “but it’s really part of my job to stop and take a closer look when something doesn’t seem right.” And that, in a nutshell, is what the Good Catch program is all about. n
580 Good Catch Nominations
from 80 areas of CHOP in 2014
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A YEAR OF GENEROSITYAs one of the largest children’s charities, The Children’s Hospital of Philadelphia relies on philanthropic donors to fuel so much of what we do. Fiscal Year 2014 (June 30, 2013 – July 1, 2014) was another great year of record-breaking generosity. But don’t take our word for it — the numbers speak for themselves. So thank you. Donors like you made this all possible.
2,819 MEMBERS
12 NEW MEMBERS
45 NEW MEMBERS
GIVING SOCIETIES
A RECORD-BREAKING YEAR FOR CHOP SIGNATURE EVENTS
OUR 2ND HIGHEST
YEAR EVER!
CAROUSEL BALL
$1.6 MILLION
DAISY DAY LUNCHEON
$1.7 MILLION
PARKWAY RUN
$1 MILLION AND A RECORD 10,500 PARTICIPANTS!
98.1 WOGL LOVES OUR KIDS RADIOTHON
$662,428CHEERS FOR CHOP
$415,000
72,936 DONORS
MADE
107,533 GIFTS
THOSE WHO EACH GAVE MORE THAN $1,000
THOSE WHO HAVE INCLUDED CHOP IN THEIR
ESTATE PLANS
RECOGNIZING LIFETIME GIVING OF $1 MILLION
OR MORE
A RECORD!
MILLION RAISED NEW
EVENT!
A BIG YEAR FOR $88 MILLION!
WE’VEREACHED
THIS YEAR WE PUBLICLY LAUNCHED A CAMPAIGN TO SUPPORT THE
BUERGER CENTER FOR ADVANCED PEDIATRIC CARE,
SET TO OPEN IN 2015!
THE BUERGER FAMILY
CONTRIBUTED $50 MILLION –
THE LARGEST GIFT EVER TO CHOP!
CHOP EMPLOYEES HAVE GIVEN
$3.1 MILLION
NAMING OPPORTUNITIES ARE STILL AVAILABLE FOR AS LITTLE AS $500
VISIT CHOPBUILDINGHOPE.ORG
GOAL: $100
MILLION
WHERE DOES THE MONEY GO?
UNRESTRICTED$7,986,638
RESEARCH, CARE AND EDUCATION$36,490,634
CAPITAL$8,504,800
ENDOWMENT$58,326,935
NEW ENDOWED CHAIRS PLEDGED
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A YEAR OF GENEROSITYAs one of the largest children’s charities, The Children’s Hospital of Philadelphia relies on philanthropic donors to fuel so much of what we do. Fiscal Year 2014 (June 30, 2013 – July 1, 2014) was another great year of record-breaking generosity. But don’t take our word for it — the numbers speak for themselves. So thank you. Donors like you made this all possible.
2,819 MEMBERS
12 NEW MEMBERS
45 NEW MEMBERS
GIVING SOCIETIES
A RECORD-BREAKING YEAR FOR CHOP SIGNATURE EVENTS
OUR 2ND HIGHEST
YEAR EVER!
CAROUSEL BALL
$1.6 MILLION
DAISY DAY LUNCHEON
$1.7 MILLION
PARKWAY RUN
$1 MILLION AND A RECORD 10,500 PARTICIPANTS!
98.1 WOGL LOVES OUR KIDS RADIOTHON
$662,428CHEERS FOR CHOP
$415,000
72,936 DONORS
MADE
107,533 GIFTS
THOSE WHO EACH GAVE MORE THAN $1,000
THOSE WHO HAVE INCLUDED CHOP IN THEIR
ESTATE PLANS
RECOGNIZING LIFETIME GIVING OF $1 MILLION
OR MORE
A RECORD!
MILLION RAISED NEW
EVENT!
A BIG YEAR FOR $88 MILLION!
WE’VEREACHED
THIS YEAR WE PUBLICLY LAUNCHED A CAMPAIGN TO SUPPORT THE
BUERGER CENTER FOR ADVANCED PEDIATRIC CARE,
SET TO OPEN IN 2015!
THE BUERGER FAMILY
CONTRIBUTED $50 MILLION –
THE LARGEST GIFT EVER TO CHOP!
CHOP EMPLOYEES HAVE GIVEN
$3.1 MILLION
NAMING OPPORTUNITIES ARE STILL AVAILABLE FOR AS LITTLE AS $500
VISIT CHOPBUILDINGHOPE.ORG
GOAL: $100
MILLION
WHERE DOES THE MONEY GO?
UNRESTRICTED$7,986,638
RESEARCH, CARE AND EDUCATION$36,490,634
CAPITAL$8,504,800
ENDOWMENT$58,326,935
NEW ENDOWED CHAIRS PLEDGED
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N. Scott Adzick, M.D., M.M.M., F.A.C.S., F.A.A.P. Surgeon-in-Chief Director, Center for Fetal Diagnosis and TreatmentC. Everett Koop Endowed Chair in Pediatric Surgery
Adzick received the John Scott Award — one of America’s oldest and most prestigious science awards — in November 2013. Past winners have included Marie Curie, Thomas Edison, Jonas Salk and the Wright Brothers. Adzick is a world-renowned pioneer in fetal surgery, performing highly complex procedures on babies while still in the womb to correct debilitating or life-threatening birth defects. He founded the Hospital’s Center for Fetal Diagnosis and Treatment, now the largest, most comprehensive fetal program in the world. Adzick was also the principal investigator at CHOP for a landmark clinical trial that demonstrated fetal surgery could substantially improve outcomes for children with spina bifida.
W h a t ’ s n e x t ?“Three words: Cure. Educate. Discover.”
Whether they are being recognized for a national honor or stepping into a new
leadership role at Children’s Hospital, these nine clinicians and scientists are at
the forefront of their specialties and a big reason CHOP remains on the cutting
edge of pediatric healthcare. See “What’s Next” for them.
2014’s SHINING STARS
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33Beverly L. Davidson, Ph.D.Director, Center for Cellular and Molecular TherapeuticsArthur Vincent Meigs Endowed Chair in PediatricsDavidson brought her stellar international reputation to Children’s Hospital to lead the center as it continues to push the frontier of gene therapy. Davidson, formerly associate director of Gene Therapy and director of the Gene Therapy Vector Core at the University of Iowa, focuses her personal research on inherited genetic diseases that attack the central nervous system, including those that start in childhood.
W h a t ’ s n e x t ?“The center will continue its research focus on blood disorders, plans to expand its efforts in advancing oncology treatments and is in a growth mode in the area of inherited brain diseases. My nine Iowa colleagues and I also bring a larger repertoire of vectors and a background in designer vectors, which will be used to introduce the ‘corrected genes’ to the appropriate affected tissues in patients. We will also be reaching out to other investigators interested in treating childhood illness with gene therapy. It’s an amazing time for this field.”
Phyllis A. Dennery, M.D., F.A.A.P.Chief, Division of NeonatologyWerner and Gertrude Henle Endowed Chair
Dennery was elected to the prestigious Institute of Medicine, making her the ninth CHOP physician or scientist recognized for major contributions to the advancement of the medical sciences, healthcare and public health. In addition to her leadership role at CHOP’s 95-bed Newborn/Infant Intensive Care Unit and 11 NICUs in partner community hospitals, she has led the International Pediatric Research Foundation and the Society for Pediatric Research. Her research is focused on oxidative stress-mediated neonatal lung gene regulation and on the biology of lung injury and repair.
W h a t ’ s n e x t ?“After we’ve done our best in the N/IICU, we sometimes send them home to an environment that’s not ideal for them. That’s why we have psychosocial programs to empower parents so they can confidently care for their sick babies and put them in the most conducive environment for the best possible development.”
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34 Beth Ely, R.N., Ph.D.Lead Nurse ResearcherCenter for Pediatric Nursing Research
and Evidence Based Practice
Ely received the 2014 Excellence in Nursing Research Award from the Society of Pediatric Nurses in recognition of her significant contributions to research in pediatric pain management. She leads CHOP’s interdisciplinary studies to understand and manage pain in patient areas including oncology, medical units and the Pediatric Intensive Care Unit. She also studies the effectiveness of cognitive behavioral and nonpharmacologic pain management strategies.
W h a t ’ s n e x t ?“We’re doing really interesting research that uses pet therapy dogs to help children with anxiety before they are sedated or have a needle stick. We’re finding that having a dog with them damps down their anxiety and makes the experience much more pleasant. We’re also exploring how children on the autism spectrum, who may not show emotion, can better be assessed for pain.”
Christopher Forrest, M.D., Ph.D.Professor of Pediatrics and Healthcare Management
Forrest was tasked by the Patient-Centered Outcomes Research Institute to build a national, multi-institutional pediatric research network, PEDSNet, that brings patients and families into the research process at the very beginning. The purpose of PEDSNet research is to provide information that will improve patient and parent decision-making so children can experience the best possible health and quality of life. PEDSNet has established a national pediatric data network, a common regulatory framework and a governance infrastructure that will reduce costs and greatly shorten the time from idea to impact on the lives of patients.
W h a t ’ s n e x t ?
“The next step is to use PEDSNet to secure new government and private grants for large-scale, high-impact research involving the member pediatric hospitals. This research network is like none other that’s been built. The more we use it, the stronger it becomes.”
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Phillip B. “Jay” Storm, M.D.Chief, Division of NeurosurgeryLeslie N. Sutton Endowed Chair in Pediatric Neurosurgery
Storm, who came to CHOP in 2003, became chief in January 2014. His surgical practice is primarily focused on brain tumors and complex spine tumors. He has pioneered several procedures and is recognized as a leader in endoscopic skull base surgery and complex reconstructive spine surgery. Storm has also spearheaded an innovative brain tumor tissue bank consortium, where samples of a wide variety of tumors can be studied and the data shared with the goal of developing more precisely targeted chemotherapy and radiation treatments.
W h a t ’ s n e x t ?“Cancers identified under the microscope as identical are actually significantly different genetically, which explains why some respond to a particular therapy while some don’t. Because pediatric brain tumors are rare compared to lung, colon, breast and prostate tumors, we need more hospitals to join the consortium to contribute their pediatric brain tumors. We’ll use the data, ultimately, to provide personalized care for each child, leading to higher survival rates and limited side effects.”
David Rubin, M.D., M.S.C.E.Co-director, PolicyLabMary D. Ames Endowed Chair in Child Advocacy
Rubin was appointed by President Obama to the federal Commission to Eliminate Child Abuse and Neglect Fatalities. He is one of 12 experts — and the only healthcare provider — named to the commission. The job is a big one: A reported 1,770 U.S. children died in 2009 because of abuse, and the actual number is probably higher. At PolicyLab, which Rubin co-founded in 2008, he focuses on child welfare issues, especially the overuse of psychotropic medications in foster children.
W h a t ’ s n e x t ?“Whether it’s my work in the Hospital, at PolicyLab or on the commission, it’s apparent that the world has become so complicated that families are struggling. We need to think innovatively about how to help families navigate the complex healthcare system through care coordination and care model strategies. Too many kids are slipping through the cracks.”
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36Bryan Wolf, M.D., Ph.D.Chair, Department of Biomedical and Health InformaticsSenior Vice President and Chief Information OfficerWilliam Wikoff Smith Endowed Chair in Pediatric Genomic ResearchWolf ’s latest role, heading up a brand-new department, is an evolution of his other job, CIO. He shepherded CHOP through the transition to a new, comprehensive electronic health record (EHR) and a restructuring of the Information Services Department. Wolf — who joined CHOP in 2001 to chair the Department of Pathology and Laboratory Medicine — will lead the integration of CHOP’s current initiatives in informatics and analytics, while leveraging the existing IT resources and health data.
W h a t ’ s n e x t ?“It will be an incredible journey to harness all the information we have and use it to improve patient care and research. CHOP has already made a substantial investment in the infrastructure, but all that data is no good to us if we can’t make it useful to researchers and clinicians. Over the next 10 years, I want to create a legacy of pediatric healthcare informatics where we establish a learning environment to perpetuate this discipline.”
Theoklis Zaoutis, M.D., M.S.C.E.Chief, Division of Infectious DiseasesThomas Frederick McNair Scott Endowed Chair in PediatricsZaoutis, associate division chief since 2009, also directs CHOP’s Center for Pediatric Clinical Effectiveness and is director of the Master of Science in Clinical Epidemiology
training program at the University of Pennsylvania. His research focuses on the epidemiology of antibiotic resistance, pediatric fungal infections and other infectious disease topics. He has engineered the development of a distinctive epidemiology research program at CHOP that is well funded by federal grants and awards from private foundations and industry.
W h a t ’ s n e x t ?“While we continue to further our research in healthcare epidemiology and infections in immunocompromised children, we will re-emphasize bench science to reinvigorate CHOP’s proud tradition of vaccine-related work and development. We will also integrate our research with the ongoing quality improvement work toward the goal of providing safer and more effective infectious disease care for patients.”
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CHIEF EXECUTIVE OFFICER Steven M. Altschuler, M.D.
PRESIDENT AND CHIEF OPERATING OFFICER Madeline Bell
EXECUTIVE VICE PRESIDENT, STRATEGIC PLANNING & BUSINESS DEVELOPMENT Matthew Cook
EXECUTIVE VICE PRESIDENT AND CHIEF SCIENTIFIC OFFICER Philip R. Johnson Jr., M.D.
EXECUTIVE VICE PRESIDENT AND CHIEF ADMINISTRATIVE OFFICER Margaret M. Jones
EXECUTIVE VICE PRESIDENT AND GENERAL COUNSEL Jeffrey D. Kahn, Esq.
EXECUTIVE VICE PRESIDENT AND CHIEF DEVELOPMENT OFFICER Stuart P. Sullivan
EXECUTIVE VICE PRESIDENT AND CHIEF FINANCIAL OFFICER Thomas J. Todorow
SENIOR VICE PRESIDENT AND CHIEF NURSING OFFICER Paula Agosto, R.N., M.H.A.
SENIOR VICE PRESIDENT, FACILITIES SERVICES, REAL ESTATE & CONSTRUCTION MANAGEMENT Douglas E. Carney, A.I.A., LEED AP
SENIOR VICE PRESIDENT, HUMAN RESOURCES Robert Croner
SENIOR VICE PRESIDENT, OUTPATIENT CLINICAL SERVICES Thomas Dole
SENIOR VICE PRESIDENT, CLINICAL SUPPORT SERVICES Charles S. Hough Jr.
SENIOR VICE PRESIDENT, CHOP CARE NETWORK Amy J. Lambert
SENIOR VICE PRESIDENT AND CHIEF INVESTMENT OFFICER Nicholas P. Procyk
SENIOR VICE PRESIDENT, RESEARCH ADMINISTRATION DEPUTY ADMINSTRATIVE DIRECTOR Mary A. Tomlinson
SENIOR VICE PRESIDENT AND CHIEF INFORMATION OFFICER Bryan Wolf, M.D., Ph.D.
VICE PRESIDENT, REVENUE CYCLE & FINANCIAL PLANNING Edward Bleacher
VICE PRESIDENT, MEDICAL OPERATIONS AND CHIEF SAFETY OFFICER Jan Boswinkel, M.D.
VICE PRESIDENT, STRATEGIC OPERATIONS LouAnn Cozzens-Westall
VICE PRESIDENT, PRIVATE INVESTMENTS Andrew Deitch
VICE PRESIDENT, MEDICAL STAFF AFFAIRS Patricia DeRusso, M.D., M.S.
VICE PRESIDENT, GOVERNMENT AFFAIRS, COMMUNITY RELATIONS & ADVOCACY Peter Grollman
VICE PRESIDENT, FINANCE Joseph Hediger
VICE PRESIDENT AND CHIEF COMPLIANCE & PRIVACY OFFICER Janet Holcombe
VICE PRESIDENT AND CHIEF QUALITY OFFICER Ron Keren, M.D.
VICE PRESIDENT, SUPPLY CHAIN Joni Rittler
VICE PRESIDENT AND CHIEF AUDIT OFFICER David Small
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The Children’s Hospital of Philadelphia’s recognition as the nation’s top pediatric hospital over the last
decade-plus is due, in large part, to the leadership of its management team and Board of Trustees. 2014
marked the 12th straight year CHOP has held or shared the No.1 ranking from U.S. News & World Report.
Leadership
39
OFFICERS
CHAIRMAN Mortimer J. Buckley
VICE CHAIRMAN Mark Fishman
HONORARY VICE CHAIRMEN Tristram C. Colket, Jr. R. Anderson Pew
CHIEF EXECUTIVE OFFICER Steven M. Altschuler, M.D.
SECRETARY Clark Hooper Baruch
TREASURER Anthony A. Latini
ASSISTANT TREASURER Thomas J. Todorow*
ASSISTANT SECRETARY Jeffrey D. Kahn, Esq.*
ASSISTANT SECRETARY Margaret M. Jones*
TRUSTEESN. Scott Adzick, M.D., M.M.M.
Steven M. Altschuler, M.D.
Clark Hooper Baruch
A. Lorris Betz, M.D., Ph.D.
Aminta Hawkins Breaux, Ph.D.
Mortimer J. Buckley
Reid S. Buerger
Dominic J. Caruso
Tristram C. Colket, Jr.
Arthur Dantchik
Mark Denneen
Mark Fishman
Lynne L. Garbose
Shirley Hill
David P. Holveck
Anthony A. Latini
Lissa Biesecker Longacre
Sharad Mansukani
James L. McCabe
John Milligan
Akiko M. Miyashita
Asuka Nakahara
Jeffrey E. Perelman
R. Anderson Pew
Gerald D. Quill
Daniel T. Roble
David B. Rubenstein
Anne Faulkner Schoemaker
Salem D. Shuchman
Kornelis Smit
Joseph St. Geme III, M.D.
Binney Wietlisbach
Nancy Abramson Wolfson
Dirk E. Ziff
EX-OFFICIOPaula Agosto, R.N., M.H.A.
Tami Benton, M.D.
Robert Doms, M.D., Ph.D.
Jeffrey A. Fine, Psy.D.
William J. Greeley, M.D.
Diego Jaramillo, M.D., M.P.H.
Michael Levine, M.D.
EMERITUS TRUSTEESLeonard Abramson
Stephen B. Burke
Ruth M. Colket
Peter C. Morse
George Reath Jr.
Stuart T. Saunders Jr.
Richard D. Wood Jr.
*Officers who are not trustees
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The Children’s Hospital of Philadelphia Foundation and The Children’s Hospital of Philadelphia
(July 1, 2014 — June 30, 2015)
The Joint Board of Trustees
40
ADOLESCENT MEDICINEOrton P. Jackson Endowed Chair in Adolescent Medicine Carol Ford, M.D.
ANESTHESIOLOGY AND CRITICAL CARE MEDICINEJames Battaglia Endowed Chair in Pediatric Pain Management Gordon Barr, Ph.D.
The Children’s Hospital of Philadelphia Endowed Chair in Critical Care Medicine Vinay M. Nadkarni, M.D.
The Children’s Hospital of Philadelphia Endowed Chair in Pediatric Anesthesiology Frank McGowan, M.D.
The Children’s Hospital of Philadelphia Endowed Chair in Pediatric Anesthesiology and Critical Care Medicine Pending appointment
John J. Downes, M.D., Endowed Chair in Pediatric Anesthesiology and Critical Care Medicine William J. Greeley, M.D., M.B.A.
Russell C. Raphaely Endowed Chair in Critical Care Medicine Robert A. Berg, M.D.
Josephine J. Templeton Endowed Chair in Pediatric Anesthesiology Clinical Education Susan C. Nicolson, M.D.
AUTISMRegional Autism Center Endowed Chair Robert T. Schultz, Ph.D.
CARDIOLOGYRobert and Dolores Harrington Endowed Chair in Pediatric Cardiology Jack Rychik, M.D.
William J. Rashkind Endowed Chair in Pediatric Cardiology Robert J. Levy, M.D.
Evelyn Rome Tabas Endowed Chair in Pediatric Cardiology Victoria L. Vetter, M.D.
Jennifer Terker Endowed Chair in Pediatric Cardiology Robert E. Shaddy, M.D.
CARDIOTHORACIC SURGERYDaniel M. Tabas Endowed Chair in Pediatric Cardiothoracic Surgery J. William Gaynor, M.D.
Alice Langdon Warner Endowed Chair in Pediatric Cardiothoracic Surgery Thomas L. Spray, M.D.
CHILD AND ADOLESCENT PSYCHIATRYFrederick H. Allen Endowed Chair in Child Psychiatry Tami D. Benton, M.D.
CHILD DEVELOPMENT AND REHABILITATION MEDICINEHenry S. Cecil, M.D., Endowed Chair in Rehabilitative Medicine at Children’s Seashore House Susan E. Levy, M.D.
The Children’s Hospital of Philadelphia Research Institute David Lawrence Altschuler Endowed Chair in Genomics and Computational Biology Joseph Zorc, M.D., M.S.C.E.
Edmond F. Notebaert Endowed Chair in Pediatric Research Philip R. Johnson Jr., M.D.
William Wikoff Smith Endowed Chair in Pediatric Genomic Research Bryan A. Wolf, M.D., Ph.D.
Mai and Harry F. West Endowed Chair in Pediatric Research Thomas Curran, Ph.D.
EMERGENCY MEDICINENicholas Crognale Endowed Chair in Pediatric Emergency Medicine Kathy N. Shaw, M.D.
Since 1988, the endowed chair program at The Children’s Hospital of Philadelphia has been an essential part of our
ability to attract and retain the most talented physicians and researchers. One of the highest scientific and academic
honors, an endowed chair also represents one of the most meaningful and permanent forms of philanthropy.
All information is as of July 1, 2014.
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Endowed Chair Holders
41John H. and Hortense Cassell Jensen Endowed Chair in Pediatric Development and Teaching Stephen Ludwig, M.D.
Justin Michael Ingerman Endowed Chair for Palliative Care Tammy Inyoung Kang, M.D.
Robert B. Johnston Jr. Endowed Chair in Pediatrics Ronald Rubenstein, M.D., Ph.D.
Stephen Ludwig Endowed Chair in Medical Education Lisa Zaoutis, M.D.
Patrick S. Pasquariello Jr. Endowed Chair in General Pediatrics Louis M. Bell, M.D.
Thomas Frederick McNair Scott Endowed Chair in Pediatrics Theoklis Zaoutis, M.D., M.S.C.E.
Stuart E. Starr Endowed Chair in Pediatrics Jonathan Spergel, M.D., Ph.D.
Richard D. Wood Jr. and Jeanette A. Wood Endowed Chair in Pediatric Diagnostic Medicine Pending appointment
HEMATOLOGYBuck Family Endowed Chair in Hematology Monica Bessler, M.D., Ph.D.
The Children’s Hospital of Philadelphia Endowed Chair in Pediatric Hematology Rodney M. Camire, Ph.D.
Jane Fishman Grinberg Endowed Chair in Stem Cell Research Mortimer Poncz, M.D.
Elias Schwartz, M.D., Endowed Chair in Hematology Kim Smith-Whitley, M.D.
ENDOCRINOLOGYLester Baker Endowed Chair in Pediatric Diabetes Michael A. Levine, M.D.
Daniel B. Burke Endowed Chair for Diabetes Research Struan Grant, Ph.D.
Thomas Moshang Endowed Chair in Endocrinology Craig Alter, M.D.
GASTROENTEROLOGY AND NUTRITIONFred and Suzanne Biesecker Endowed Chair in Pediatric Liver Disease David A. Piccoli, M.D.
Irma and Norman Braman Endowed Chair for Research in GI Motility Disorders Robert O. Heuckeroth, M.D., Ph.D.
Colman Family Endowed Chair in Pediatric Inflammatory Bowel Disease Robert N. Baldassano, M.D.
Jean Cortner Endowed Chair in Pediatric Gastroenterology Virginia A. Stallings, M.D.
Suzi and Scott Lustgarten Endowed Chair for Clinical Care of GI Motility Disorders Ritu Verma, M.B., Ch.B.
GENERAL PEDIATRICSThe Children’s Hospital of Philadelphia Endowed Chair in the Prevention of Child Abuse and Neglect Cindy Christian, M.D.
David Cornfeld Endowed Chair in Pediatrics Richard Rutstein, M.D.
Frank E. Weise III Endowed Chair in Pediatric Hematology Gerd Blobel, M.D., Ph.D.
HUMAN GENETICS AND MOLECULAR BIOLOGYLetitia B. and Alice Scott Endowed Chair in Human Genetics and Molecular Biology Elaine H. Zackai, M.D.
Charles E.H. Upham Endowed Chair in Pediatric Medicine Beverly S. Emanuel, Ph.D.
IMMUNOLOGY AND INFECTIOUS DISEASESMaurice R. Hilleman Endowed Chair in Vaccinology Paul Offit, M.D.
Jeffrey Modell Endowed Chair in Pediatric Immunology Research Pending appointment
Stanley Plotkin Endowed Chair in Pediatric Infectious Diseases Jeffrey M. Bergelson, M.D.
Frank R. Wallace Endowed Chair in Infectious Diseases Kathleen Sullivan, M.D., Ph.D.
INTERNATIONAL ADOPTIONWawa Endowed Chair in International Adoption Susan Friedman, M.D.
MEDICAL ETHICSSteven D. Handler Endowed Chair in Medical Ethics Chris Feudtner, M.D., Ph.D., M.P.H.
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Alexander B. Wheeler Endowed Chair in Neurosurgical Research Adam Resnick, Ph.D.
NURSINGRuth M. Colket Endowed Chair in Pediatric Nursing Barbara Medoff-Cooper, Ph.D., R.N.
ONCOLOGYLouis and Amelia Canuso Family Endowed Chair for Clinical Research in Oncology Frank M. Balis, M.D.
Giulio D’Angio Endowed Chair in Neuroblastoma Research John M. Maris, M.D.
Audrey E. Evans Endowed Chair in Pediatric Oncology Garrett M. Brodeur, M.D.
Joshua Kahan Endowed Chair in Pediatric Leukemia Research Carolyn Felix, M.D.
Yetta Deitch Novotny Endowed Chair in Pediatric Oncology Stephan Grupp, M.D., Ph.D.
Richard and Sheila Sanford Endowed Chair in Pediatric Oncology Angela J. Waanders, M.D., M.P.H.
OPHTHALMOLOGYMabel E. Leslie Endowed Chair in Pediatric Ophthalmology Monte Mills, M.D.
ORTHOPEDIC SURGERY Richard M. Armstrong Jr. Endowed Chair in Pediatric Orthopedic Surgery John P. Dormans, M.D.
METABOLIC DISEASEWilliam T. Grant Endowed Chair in Child Development and Rehabilitation Marc Yudkoff, M.D.
NEONATOLOGYGisela and Dennis Alter Endowed Chair in Pediatric Neonatology Haralambos Ischiropoulos, Ph.D.
Werner and Gertrude Henle Endowed Chair Phyllis Dennery, M.D.
Harriet and Ronald Lassin Endowed Chair in Pediatric Neonatology Scott Lorch, M.D.
NEPHROLOGYLaffey-Connolly Endowed Chair in Pediatric Nephrology Susan Furth, M.D.
NEUROLOGYCatherine D. Brown Endowed Chair in Pediatric Epilepsy Dennis Dlugos, M.D.
The Children’s Hospital of Philadelphia Endowed Chair in Pediatric Neurology Robert R. Clancy, M.D.
Grace R. Loeb Endowed Chair in Neurosciences Brenda Banwell, M.D.
Hubert J.P. and Anne Faulkner Schoemaker Endowed Chair in Pediatric Neuro-Oncology Peter C. Phillips, M.D.
NEUROSURGERYLeslie N. Sutton Endowed Chair in Pediatric Neurosurgery Phillip B. Storm Jr., M.D.
Children’s Hospital of Philadelphia Endowed Chair in Pediatric Orthopedic Surgery Pending appointment
Dr. Bong S. Lee Endowed Chair in Pediatric Orthopedics Maurizio Pacifici, Ph.D.
OTOLARYNGOLOGYThe Children’s Hospital of Philadelphia Endowed Chair in Pediatric Otolaryngology Ken Kazahaya, M.D.
The Children’s Hospital of Philadelphia Endowed Chair in Pediatric Otolaryngology and Pediatric Airway Disorders Ian N. Jacobs, M.D.
E. Mortimer Newlin Endowed Chair in Pediatric Otolaryngology and Human Communication Ralph Wetmore, M.D.
William Potsic Endowed Chair in Pediatric Otolaryngology and Childhood Communication Pending appointment
PATHOLOGYMichael and Charles Barnett Endowed Chair in Pediatric Mitochondrial Medicine and Metabolic Diseases Douglas Wallace, Ph.D.
Evelyn Willing Bromley Endowed Chair in Clinical Laboratories and Pathology Michael J. Bennett, Ph.D.
Evelyn Willing Bromley Endowed Chair in Pathology and Clinical Laboratories Nancy B. Spinner, Ph.D.
Mildred L. Roeckle Endowed Chair in Pathology Andrei Thomas-Tikhonenko, Ph.D.
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43Peter Randall Endowed Chair in Plastic and Reconstructive Surgery Scott P. Bartlett, M.D.
PRESIDENT’S SCHOLARST. Hewson Bache Endowed Chair in Pediatrics Robert W. Doms, M.D., Ph.D.
John M. Keating Endowed Chair in Pediatrics Pending appointment
Arthur Vincent Meigs Endowed Chair in Pediatrics Beverly Davidson, Ph.D.
R.A.F. Penrose Endowed Chair in Pediatrics Stewart A. Anderson, M.D.
Louis Starr Endowed Chair in Pediatrics Pending appointment
PULMONARY MEDICINERobert Gerard Morse Endowed Chair in Pediatric Pulmonary Medicine Julian Allen, M.D.
RADIOLOGYPatricia Borns Endowed Chair in Radiology Education Janet R. Reid, M.D.
The Children’s Hospital of Philadelphia Endowed Chair in Pediatric Neuroradiology Robert Zimmerman, M.D.
Kenneth E. Fellows Endowed Chair in Radiology Quality and Patient Safety James S. Meyer, M.D.
John Westgate Hope Endowed Chair in Radiology Faculty Development Kassa Darge, M.D., Ph.D.
Lucy Balian Rorke-Adams Endowed Chair in Neuropathology Pending appointment
Evelyn and George Willing Endowed Chair in Pathology Research Janis Burkhardt, Ph.D.
PEDIATRICSLeonard and Madlyn Abramson Endowed Chair in Pediatrics Joseph W. St. Geme III, M.D.
Mary D. Ames Endowed Chair in Child Advocacy David Rubin, M.D., M.S.C.E.
William H. Bennett Professor of Pediatrics at the University of Pennsylvania School of Medicine Katherine High, M.D.
Alan R. Cohen Endowed Chair in Pediatrics Peter Adamson, M.D.
Distinguished Chair in the Department of Pediatrics Carole Marcus, MB.B.Ch.
Distinguished Chair in the Department of Pediatrics Gail Slap, M.D.
Nancy Wolfson Endowed Chair in Health Services Research Jeffrey H. Silber, M.D., Ph.D.
PLASTIC AND RECONSTRUCTIVE SURGERYMary Downs Endowed Chair in Pediatric Craniofacial Treatment and Research Jesse A. Taylor, M.D.
Friends of Brian Endowed Chair in Pediatric Plastic and Reconstructive Surgery Pending appointment
Oberkircher Family Endowed Chair in Pediatric Radiology Timothy Roberts, Ph.D.
William L. Van Alen Endowed Chair in Pediatric Radiology Diego Jaramillo, M.D.
RHEUMATOLOGYJoseph Lee Hollander Endowed Chair in Pediatric Rheumatology Edward M. Behrens, M.D.
SURGERYC. Everett Koop Endowed Chair in Pediatric Surgery N. Scott Adzick, M.D., M.M.M.
Josephine J. and John M. Templeton Jr. Endowed Chair in Pediatric Trauma Michael L. Nance, M.D., F.A.A.P., F.A.C.S.
THORACIC AND FETAL SURGERYRuth M. and Tristram C. Colket, Jr. Endowed Chair in Pediatric Surgery Alan W. Flake, M.D.
George Leib Harrison Endowed Chair in Fetal Therapy Mark Paul Johnson, M.D.
UROLOGYLeonard and Madlyn Abramson Endowed Chair in Pediatric Urology Douglas A. Canning, M.D.
John W. Duckett Jr. Endowed Chair in Pediatric Urology Stephen A. Zderic, M.D.
Howard M. Snyder III Endowed Chair in Pediatric Urology Pending appointment
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Financial Summary
(1) Includes unrestricted, temporarily restricted and permanently restricted contributions*Reclassified for comparative purposes
USES OF REVENUE For the Fiscal Year Ending June 30
SOURCES OF REVENUE For the Fiscal Year Ending June 30
FY 2014 FY 2013* FY 2012*
Net Patient Service Revenue $2,021,363,000 $1,849,940,000 $1,678,604,000
Other Operating Revenue 104,211,000 105,318,000 103,442,000
Contributions (1) 64,074,000 65,692,000 46,560,000
Research 211,834,000 218,931,000 184,851,000
TOTAL SOURCES OF REVENUE $2,401,482,000 $2,239,881,000 $2,013,457,000
FY 2014 FY 2013* FY 2012*
Salaries, Wages and Employee Benefits $1,121,520,000 $1,051,244,000 $977,164,000
Supplies and Expenses 420,851,000 406,539,000 370,414,000
Depreciation 119,955,000 119,151,000 124,139,000
Interest 8,383,000 14,884,000 17,893,000
Research Expenses 334,155,000 327,944,000 299,464,000
Uncompensated Care 129,101,000 105,838,000 73,888,000
Provisions for Programmatic Investments 267,517,000 214,281,000 150,495,000
TOTAL USES OF REVENUE $2,401,482,000 $2,239,881,000 $2,013,457,000
Did you know?Supplies and expenses
cover everything patients need — from meds and
blankets to surgical clamps and maintenance
of MRI machines.
USE
S O
F R
EV
EN
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2014 SALARIES, WAGES
AND EMPLOYEE BENEFITS:$1,121,520,000
SUPPLIES AND EXPENSES:$420,851,000
DEPRECIATION: $119,955,000
INTEREST: $8,383,000
RESEARCH EXPENSES:$334,155,000
UNCOMPENSATED CARE:$129,101,000
PROVISIONS FOR PROGRAMMATIC INVESTMENTS:$267,517,000
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45ASSETS For the Fiscal Year Ending June 30
LIABILITIES AND NET ASSETS For the Fiscal Year Ending June 30
Combined Balance Sheet
FY 2014 FY 2013 FY 2012
Cash and Short-term Investments $484,826,000 $407,767,000 $275,286,000
Receivables 245,931,000 304,705,000 264,045,000
Other Current 91,472,000 93,254,000 100,360,000
Total Current Assets $822,229,000 $805,726,000 $639,691,000
Investments 1,958,345,000 1,669,173,000 1,624,075,000
Property, Plant and Equipment (Net) 1,952,896,000 1,742,905,000 1,606,769,000
Other Assets 76,304,000 79,666,000 64,663,000
TOTAL ASSETS $4,809,774,000 $4,297,470,000 $3,935,198,000
Did you know?The 2014 bump in Property, Plant and Equipment is
attributed to the ongoing construction of the 700,000-square-foot Buerger Center for Advanced Pediatric Care, which
will set the standard for state-of-the-art ambulatory care when it opens in 2015.
FY 2014 FY 2013 FY 2012
Current Portion of Long-term Debt $15,523,000 $14,850,000 $16,525,000
Accounts Payable and Accrued Expenses 342,533,000 331,169,000 294,777,000
Total Current Liabilities $358,056,000 $346,019,000 $311,302,000
Long-term Debt 736,297,000 751,820,000 756,870,000
Other Liabilities 297,906,000 302,361,000 354,085,000
Total Long-term Liabilities $1,034,203,000 $1,054,181,000 $1,110,955,000
Unrestricted Net Assets 3,047,668,000 2,568,101,000 2,215,660,000
Temporarily Restricted Net Assets 213,612,000 182,193,000 154,694,000
Permanently Restricted Net Assets 156,235,000 146,976,000 142,587,000
Total Net Assets $3,417,515,000 $2,897,270,000 $2,512,941,000
TOTAL LIABILITIES AND NET ASSETS $4,809,774,000 $4,297,470,000 $3,935,198,000
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Hospital StatisticsSTATISTICAL HIGHLIGHTS For the Fiscal Year Ending June 30
FY 2014 FY 2013 FY 2012
Hospital Admissions 28,156 28,996 28,761
Patient Days 159,045 154,551 151,266
Number of Beds 500 494 480
Number of Employees 11,649 11,048 10,701
OUTPATIENT VISITS For the Fiscal Year Ending June 30
FY 2014 FY 2013 FY 2012
CHOP Care Network Specialty Care 363,497 349,773 343,525
CHOP Care Network, West/ South Philadelphia Communities 117,110 117,963 116,284
CHOP Care Network, Suburban Communities 581,161 590,622 576,525
Emergency Department 86,134 90,378 88,212
Day Surgery 18,065 18,342 18,369
Day Medicine 25,207 26,046 24,230
TOTALS 1,191,174 1,193,124 1,167,145
DAY SURGERY
DAY MEDICINE
EMERGENCY DEPARTMENT
CHOP CARE NETWORK, WEST/SOUTH PHILADELPHIA COMMUNITIES
CHOP CARE NETWORK SPECIALTY CARE
CHOP CARE NETWORK, SUBURBAN COMMUNITIES
100K 200K 300K 400K 500K 600K
2014Outpatient Visits
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Hospital Statistics
414
956
2,414
1,913
1,259
1,434
8,891
2,640
46
91
36
200
103
107
44
58266
86
259
538
196
281
128
81
82956
62
66
508
278152
413
735
51
85
30
43
66 Pennsylvania: 18,877 = 8,000+ Admissions = 900+ Admissions = 200+ Admissions = 30+ Admissions = Other Counties Combined
New Jersey: 7,291 = 1,000+ Admissions = 500+ Admissions = 150+ Admissions = 30+ Admissions
Sussex
Passaic
Bergen
Hudson
Essex
Union
MorrisWarren
Hunterdon
Somerset
MiddlesexMonmouth
Mercer
Ocean
Burlington
CamdenGloucester
Salem
Cumberland
Cape May
Atlantic
ADMISSIONS FROM PENNSYLVANIA AND NEW JERSEY BY SELECTED COUNTIES For the Fiscal Year Ending June 30
353 Admitted patients from
other Pennsylvania counties
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Hospital Statistics (continued)GRADUATE MEDICAL EDUCATION For the Fiscal Year Ending June 30
Dept. of PediatricsNo. of Trainees
131 Residents 167 Fellows
Dept. of Anesthesiology and Critical Care Medicine
No. of Trainees
31 Fellows
Dept. of SurgeryNo. of Trainees
36 Fellows
Dept. of RadiologyNo. of Trainees
13 Fellows
Dept. of Child and Adolescent Psychiatry
No. of Trainees
13 Fellows
Dept. of Pathology No. of Trainees
3 Fellows
Total:397
In FY14, CHOP had trainees in 57 accredited and non-accredited training programs.
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Research StatisticsALL SOURCES OF FUNDING For the Fiscal Year Ending June 30
BREAKDOWN OF EXTERNAL FUNDING For the Fiscal Year Ending June 30
Percentage Dollar Amount
External 73.28% $212,352,193
Endowment 5.36% 15,545,425
Hospital 16.36% 47,399,926
Other 5.00% 14,491,701
TOTAL $289,789,245
Percentage Dollar Amount
Federal 57.19% $121,446,532
Federal – Stimulus 0.53% 1,123,596
Industrial 5.51% 11,698,728
State/Local 2.07% 4,396,937
Children’s Oncology Group – Federal 15.80% 33,549,426
Children’s Oncology Group – Foundation/Industry 6.83% 14,507,492
Foundation 8.35% 17,731,425
Other 3.72% 7,898,057
TOTAL $212,352,193
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Did you know?The number of publications by CHOP researchers
has grown steadily, from 1,103 in 2012, to 1,217 in 2013, and to 1,504 in 2014.
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Research Statistics (continued)RESEARCH LOCATIONS AND SPACE For the Fiscal Year Ending June 30
Leonard and Madlyn Abramson Pediatric Research Center
359,222 Sq. Ft.
Ruth and Tristram Colket, Jr. Translational Research Building
289,325 Sq. Ft.
3550 Market Street
2,408 Sq. Ft. 3535 Market Street
143,584 Sq. Ft.
CHOP Main Campus
3,408 Sq. Ft.
Total: 797,947 Sq. Ft.
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Charitable GivingGIFTS BY DESIGNATION For the Fiscal Year Ending June 30
DONORS AND DOLLARS For the Fiscal Year Ending June 30
ENDOWED CHAIRS For the Fiscal Year Ending June 30
Percentage Dollar Amount*
Capital 7.6% $8,504,800
Research, Care and Education 32.8% 36,490,634
Endowment 52.4% 58,326,935
Unrestricted 7.2% 7,986,638
TOTAL $111,309,007
= Money Raised= Number of DonorsMoney Raised:
$130,816,161No. of Donors:
66,500
2013
Money Raised:$111,309,007No. of Donors:
72,936
2014Money Raised:$76,827,917No. of Donors:
61,678
2012
101Fully
Funded Chairs
14Pledged Chairs
5President’s
Scholar Chairs
*Amounts include total cash and pledges received
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View the online Annual Report at www.chop.edu/ar.
The 2014 Annual Report ofThe Children’s Hospital of Philadelphia
Produced by the Marketing, Weband Public Relations Department
Front and Back Covers: Molly, 11 months
Inside Front Cover: Brylan, 4
Page 2: Jackie, 4, and William, 3
Page 37: Sophia, 4
Opposite: Charlee, 7
©2015 The Children’s Hospital of Philadelphia. All Rights Reserved. 9453/625/2-15
