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Where we’ve been.. And where we’re going George Thoma

Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

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Page 1: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Where we’ve been.. And where we’re going

George Thoma

Page 2: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

NASA’s ATS-6 Satellite

Page 3: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Communications Technology Satellite (CTS)

A joint US-Canadian satelliteprogram

Footprint: Fort Yukon to Bethesda

Ku Band (12-14GHz)Small antenna for earth station

Page 4: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

10-foot antenna, rural Alaska

Page 5: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Telemedicine via satellite

2-way broadcast quality video

Audio, data

Page 6: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Broadcast studio at NLM/Lister Hill Center

Page 7: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Distance learning, conferences – NIH to sites in West and Alaska

Page 8: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Motivations

Does the project

• Help diagnose/screen for diseases (especially in resource limited areas)?

• Create efficiencies in NLM’s core mission?

• Bring NLM’s historic treasures to a wider audience?

• Help people in any way, e.g., in the midst of a mass disaster?

Page 9: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Motivations • Help diagnose/screen for diseases (especially in resource limited

areas)?• Automate the detection and localization of TB or cardiomegaly in CXR

• Automate the detection of malaria from RBC in blood smear images

• Automate the detection of cervical cancer in colposcopic and histology images

Page 10: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Spine ImagesEarliest foray into medical images ~1992

Page 11: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

CDC/NCHS Tractor trailers parked near Chester, PA

Page 12: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Inside the trailers

Page 13: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Motivations • Create efficiencies in NLM’s core mission?

Homemade Bookscanner: preservation, ILL Automated Interlibrary Loan

Scanned images displayedprior to transmission

Page 14: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Motivations • Create efficiencies in NLM’s core mission?

MARS System ~1995

Automated extraction of bibliographic data in medical articles to build MEDLINE citations

Machine learning, image processing

Page 15: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Daniel Le, Ph.D.

US Patent 5,592,572January 7, 1997

Automated portrait/landscape mode detection on a binary image

Page 16: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Motivations

• Bring NLM’s historic treasures to a wider audience?

TTP Kiosk TTP Website TTP on the iPad

Page 17: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

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Page 18: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical
Page 19: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Motivations

• Help people in any way, e.g., in the midst of a mass disaster?

NLM People Locator

>50 earthquakes, floods, tsunamis

First used in Haiti2010

Page 20: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Capitol Shield disaster exercise – October 2011

TriagePic used for family reunification

Arrival of “victims” at Suburban Hospital

Hospital staff use Lister Hill Center’s TriagePic to capture photo and metadata

Page 21: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

To be passed on to the next longest serving staff member – Dr. Craig Locatis

Page 22: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Live long and prosper!

And boldly go where no man has gone before..

Page 23: Where we’ve been.. And where we’re going Retirement Talk2018.pdf · • Automate the detection of malaria from RBC in blood smear images • Automate the detection of cervical

Live long and prosper!

And boldly go where no man has gone before..one