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Introduce CyberColloids Who, Why and What we do H lth d d Health and seaweed Source of nutrition: fact or fiction

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Page 1: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

◦ Introduce CyberColloids Who, Why and What we do

H lth d d◦ Health and seaweedSource of nutrition: fact or fiction

Page 2: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

A Contract Research to Business Development company

Page 3: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Th l i b t th t i t t ith tThey are polymeric substances that interact with water to thicken and or form gelling networks.

THICKENING GELLING

Page 4: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

'Hydrocolloids'- What’s available?

Trees

E d t

Microorganisms

F t ti

Seaweeds

Dried

Plant

F t

Seeds

FlExudate FermentationsSeaweedsFragmentsFlour

SOURCINGEXTRACTION

TRANSFORMATIONTRANSFORMATIONPURIFICATION

DRYINGMILLING

Gum ArabicKaraya

Tragacanth

XanthanGellan

AlginateCarrageenan

AgarPectin

Cellulosics

Guar gumLBG

TEST CONTROLS, BLENDING, STANDARDISATION,SPECIFIC APPLICATION CONTROL

PLUS OTHER INGREDIENTS

TEXTURE PRODUCTS/STABILIZERS

Page 5: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

CyberColloids is a group of experts and companies working together to create acompanies working together to create a

centre of excellence of polysaccharides with a view to enable companies to costa view to enable companies to cost

effectively add value through research and innovationinnovation

2008

Page 6: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

CyberColloids – Our Response

HydrocolloidProducers

Raw MaterialSuppliersProducers pp

Universities Application

Centers

CyberColloidsAssociates(Product

)

CyberColloidsA center of Excellence

f P l h idCenters Experts)for Polysaccharides

UCC

Food & Pharma Industrial

UCCCIT

ULSTERREADING

To Create Value and Innovate CostTo Create Value and Innovate Cost

FRAUNHOFERIOWA

To Create Value and Innovate Cost To Create Value and Innovate Cost EffectivelyEffectively

Page 7: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate
Page 8: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Pleasant Healthy FoodTexture Nutrition

Pleasant Healthy Food

Consumer PreferenceConsumer Preference

Sensory AnalysisSensory Analysis

Rheological Measurements

Physiology Studies

y yy yFood ProcessingFood Processing

Measurements

Food Ingredients

StudiesNutraceuticalsChemistry &Chemistry &

ProcessingProcessing

RAW MATERIALSPlants Algae Microrganism

Page 9: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

New Carrageenan

New Cellulosics Fat ReplacerNew Fruit

Fiberfactories

Potato Fiber

Protein/Polysaccharide Texture Systems Biomodified Guar/

Soluble fiberNew Biogum/ fNew Biogum/Prebiotics

Page 10: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate
Page 11: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Recognised sea vegetablesSpecies Issues

Brown seaweeds

Market acceptance

Food grade availablity

Brown seaweedsAlaria esculenta EU yesAscophyllum nodosum EU commercially sustainable, not eaten in IrelandFucus vesiculosus EU not eaten in IrelandFucus serratus EU not eaten in IrelandFucus serratus EU not eaten in Ireland Himanthalia elongata EU yesLaminaria digitata EU, Asia yes commercially sustainable, potentially high in IodineRed seaweedsChondrus crispus EU yesChondrus crispus EU yesGracilaria verrucosa EU not eaten in Ireland Palmaria palmata EU yes

EU Asia yesG reen seaw eedsPorphyra spp.G reen seaw eeds

EU yes can accumulate organic pollutantsUlva spp.

Page 12: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Seaweeds contain most major nutritional groupsSeaweeds contain most major nutritional groups at levels similar to or greater than traditional sources

`

more calciumnon animal source of

B12

more fibre

B12

high protein <47% in some reds

more iron natural “multi vitamin”low fat <2%more iron natural multi vitamin

high in minerals and vitamins

Page 13: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Gastro Intestinal effectsAlginate - Bulking, Slow release, lower bowel fermentation

R f Al i t l i h l t l (3) bl dReferences: Alginate lowering cholesterol (3), blood glucose levels (4), Post prandial glucose release in diabetics (5); metabolism in lower intestine (6)

l l b l fLaminarin - Beta glucan, lower bowel fermentationReferences: A beta glucan, preventing putrefactive elements in lower gut (7), prebiotic activity (8)g , p y

Porphyran (Nori) –Found to induce a bacterial adaptation that led to greater fermentation in lower intestine whereasgreater fermentation in lower intestine whereas brown seaweed, wakame, was just undigested (9)

Page 14: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Dulse polyphenols have been found to be potent antioxidants in vitro (23)

Antioxidant nature from polyphenols (24) – Longer acting than ascorbic acidacting than ascorbic acid1g of Fucus vesiculosus extract has been found to have a similar antioxidant level to 11.7mls of red wine(25)wine(25)

Beverages made from seaweeds have compared favourably with vitamin E and vitamin C in FRAP tests (26) ll h f(26) especially concentrates thereofPolysaccharide antioxidant (27) – Porphyra sulphated polysaccharides showed superoxide, peroxide andpolysaccharides showed superoxide, peroxide and hydroxyl inhibition

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2008

Page 16: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Seaweed and flavour?

TASTE is keyTASTE is key

recognised use as sea vegetablesi d f U i flrecognised use for Umami flavours

original source of MSGprotein richprotein richhigh levels of free amino acidshigh levels of free glutamatesg e e s o ee g uta atescooking processes known to release

bound amino acidshi h l l f ' l id IMPhigh levels of 5' nucleotides e.g. IMPrich in mineralscurrently under exploited resourcecurrently under exploited resource

Page 17: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

VOLATILES

f

NON-VOLATILE

f

ALDEHYDES OF PUFAs

from

PROTEINS

from

CAROTENOIDS NUCLEOTIDES

TERPENOIDS MINERALS

METHYL AMINES SUGARS

ORGANO SULPHURS LIPIDS

Page 18: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

RED GREEN BROWN

FISHY OXIDISED PUFAS & METHYL AMINES

MEATY ALDEHYDES OF PUFAs (C16)

MARINE DMS DMS IODINEALDEHYDES OF PUFAs (>C9)ALDEHYDES OF PUFAs (>C9)

FRESH – GREEN ALDEHYDES OF PUFAs (C6-C9)CAROTENOIDS TERPENOIDS

SPICY PEPPERYSPICY – PEPPERY

SWEET RICH IN POLYSACCHARIDESMANNITOL

SALTY RICH IN MINERALS

MUSHROOM LENTHIONINE

UMAMI GLUTAMATE GLUTAMATEUMAMI GLUTAMATE GLUTAMATE5'-RIBONUCLEOTIDES 5'-RIBONUCLEOTIDES

AMINO ACIDS AMINO ACIDS

OFF NOTES SULPHUR AMINO ACIDS

Page 19: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Whole seaweed for soups

Garnish for seafood

Ground kombufor flavour

Sauce with Nori

Nori rolls

Sauce with Nori

Whole foodKombu flavour

dressing

Garnish on bacon

Soy milk with kombu

Processed Food IngredientSemi-processed for

garnish or condiment

F i d d

Soy milk with kombu

Fried seaweedsnack

Included inbiscuits

Extract in paté

Sports drinkwith seaweed

extract

Energy drinkwith Kombu

extractBeer withseaweed Slimming patches

2008

p

Page 20: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Total Sample 45Total Sample 45Salads 5Prepared Meals 4Seasonings 4Seasonings 4Dry Soup 3Fish Products 3Meat Products 3Meat Substitutes 3Vegetables 3Meal Kits 2Meal Replacements & Other Drinks 2Wet Soup 2Baking Ingredients & Mixes 1B d & B d P d t 1Bread & Bread Products 1Hors d'oeuvres/Canapes 1Instant Noodle, Pasta & Rice 1Malt & Other Hot Beverages 1Malt & Other Hot Beverages 1Nuts 1Pastry Dishes 1Rice 1Rice 1Shelf-Stable Desserts 1Snack Mixes 1Stocks 1

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Ingredients: Peanut, Rice, Potato Starch, Corn Starch, Cassava Starch, Vegetable Oils (Vegetable Based) (Rapeseed Oil, Sunflower Seed Oil), Salt, Soy Sauce (Soybean, Wheat, Salt), White Sugar, Wheat Flour, Aromatic Herbs (Aromatic), Spices, Maltodextrin, Glucose Syrup, Rice Flour, Garlic Flavouring Substances (Wheat Soybean) Onion Tomato (Powdered) Glucose AlgaeGarlic, Flavouring Substances (Wheat, Soybean), Onion, Tomato (Powdered), Glucose, Algae(Marine Origin) (Kelp), Yeast Extracts (Extract), colourings (Curcumin, Carmine, Paprika Oleoresin (Extract)), Pepper Extract (Hot, Extract), Dried Eggs (Powdered), Hot Pepper Powder (Hot, Powdered), Citric Acid (Food Acids), Sodium Acetates (Preservatives), Hydrolyzed Soy P t i (H d l d)*f h d th dProtein (Hydrolyzed)*from hens reared on the ground

Page 22: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Vanilla Flavoured Seaweed Protein Shake R d ID 1866842Record ID: 1866842Company: Natusor

Gezondheidsproducten

Brand: Natusor Category: Other BeveragesCategory: Other BeveragesSub-Category: Meal Replacements

& Other Drinks Country: Netherlands Store Name: G&W (Gezond &

Wel)Wel)Store Type: Natural/Health Food

Store Store Address: Rotterdam 3054 GE Date Published: Aug 2012 Product source: ShopperppLaunch Type: New ProductPrice in local currency: 29.95 Price in US Dollars: 37.22 Bar Code: 8718164640650

Ingredients: Milk Proteins, Whey Protein Concentrate (Concentrate), Egg Proteins, Carnitine Tartrate, Glucose, Vanilla Flavour, Spirulina, Chlorella, Guar Gum, Kelp, Wakame Seaweed, Xanthan Gum, Sucralose

Page 23: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Vegetable Stock Record ID: 1843198 Company: Marks & Spencer B d M k & S fBrand: Marks & Spencer for

Creative Cooking Category: Sauces &

Seasonings Sub-Category: StocksSub Category: StocksCountry: UK Store Name: Marks & Spencer Store Type: Department Store Store Address: London N22 6BX Date Published: Jul 2012Product source: Shopper Launch Type: New Product Price in local currency: 3.00 Price in US Dollars: 4 77Price in US Dollars: 4.77Price in Euros: 3.78 Bar Code: 00851947 Ingredients: Waters Onion Swede Leek Carrot Mushroom Kelp Salt Ingredients: Waters, Onion, Swede, Leek, Carrot, Mushroom, Kelp, Salt

Page 24: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Soy Marinated Chicken Breast Record ID: 1836038Company: Marks & SpencerBrand: Marks & Spencer

Simply Fuller LongerCategory: Meals & Meal

CentersCentersSub-Category: Prepared MealsCountry: Ireland Store Name: Marks & Spencer Store Type: Department Store Store Address: DublinStore Address: DublinDate Published: Jul 2012Product source: Shopper Launch Type: New Variety/Range

Extension Price in local currency: 5.99Price in local currency: 5.99Price in US Dollars: 7.65 Bar Code: 00847193

Ingredients: Chargrilled soy marinated chicken breast (21%) (Chicken Meat, Waters, Soy Sauce (Waters,

Soybean, Wheat (Roasted), Salt), Brown Sugar, Ginger (Puree, Pure), Cornflours, Rice Wines (Shaoxing), Mirin (Glucose Syrup, Waters, White Sugar, Miso (Fermented) (Rice, Glucose Syrup, Ethyl Alcohol, Salt, Waters), Rice Vinegar, Ethyl Alcohol, acidity regulator (Malic Acid (Food Acids)), Tartaric Acid (Food Acids)), Glucose (Smoked)), Chicken Stock (Waters, Chicken Meat), Rice (Cooked) (Waters, Rice Flour), Savoy Cabbage, Black Fungus, Mung Bean, Mushroom, Miso (Paste) (Soybean (Fermented) (Soybean, Waters, Salt, Wheat Flour), Waters, Salt) Kelp (Waters Kelp) Onion Cornflo rs Haricot Bean Sesame Seed Oil GingerSalt), Kelp (Waters, Kelp), Onion, Cornflours, Haricot Bean, Sesame Seed Oil, Ginger(Puree, Pure), Chili Pepper, Mushroom Stock (Mushroom, Waters, White Sugar, Salt, RapeseedOil, Mushroom (Dry)), Single Cream, Beef Gelatine, Rapeseed Oil, Garlic Puree (Puree, Pure), Salt, Shiitake Mushroom, Anise Star

Page 25: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Chicken & Vegetable Hotpot Record ID: 1744228 Company: Marks & SpencerCompany: Marks & SpencerBrand: Marks & Spencer

Simply Fuller LongerCategory: Meals & Meal

Centers Sub-Category: Prepared MealsSub Category: Prepared MealsCountry: UK Store Name: Marks & Spencer Store Type: Department Store Store Address: London SE13 6JG Date Published: Mar 2012Date Published: Mar 2012Product source: Shopper Launch Type: New Packaging Price in local currency: 4.19 Price in US Dollars: 6.70 Price in Euros: 5.03Price in Euros: 5.03Bar Code: 00774666

Ingredients: Potato (Slices, Roasted) (Potato, Rapeseed Oil), Chicken Stock (Roasted) (Waters, Chicken Meat, Onion, Carrot, Leek, Garlic, Parsley, Bay Leaf, White Pepper), Chicken Meat (Cooked), Green Lentil (Green) Onion Sa o Cabbage Carrot Leek (Slices) Kelp (Waters Kelp)Green Lentil (Green), Onion, Savoy Cabbage, Carrot, Leek (Slices), Kelp (Waters, Kelp), Wheat Flour, Tomato Puree (Puree, Pure), Cornflours, Salt, Rapeseed Oil, Mushroom Stock (Mushroom, Waters, White Sugar, Salt, Rapeseed Oil, Mushroom (Dry)), Parsley, Beef Gelatine, Garlic Puree (Puree, Pure), Black Pepper (Cracked), Caramel I Plain (Plain, Food Colours) Anise StarColours), Anise Star

Page 26: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Organic Pumpkin Cream SoupSoupRecord ID: 1735287 Company: Anko Brand: Sabores de Navarra Category: Soupg y pSub-Category: Wet SoupCountry: Spain Store Name: Aldi Supermercados Store Type: Supermarket Store Address: Cordoba 14007Store Address: Cordoba 14007Date Published: Feb 2012 Product source: Shopper Launch Type: New Product Price in local currency: 2.19Price in US Dollars: 2.90Bar Code: 8423674400808

Ingredients: Pumpkin, Quinoa, Carrot, Onion, Kombu Seaweed, Waters, Extra Virgin Olive Oil (Extra, Extra Virgin), Sea Salts, Spices (Natural)

Page 27: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Nordic Style Herring Fillet with Seaweed Record ID: 1833682Company: Larsen Danish

Seafood Brand: Larsen Küsten SnackCategory: Processed FishCategory: Processed Fish,

Meat & Egg ProductsSub-Category: Fish Products Country: Austria Store Name: Julius Meinl am

GrabenStore Type: Gourmet Store Store Address: Vienna 1010 Date Published: Jul 2012 Product source: ShopperProduct source: ShopperLaunch Type: New Product Price in local currency: 1.99 Price in US Dollars: 2.54 Bar Code: 4018344111715 Ingredients: Herring (Fillet), Wakame Seaweed (Brown Algae (Undaria Pinatifida)), Vegetable Oils

(Vegetable Based), Salt, Glucose, Spices, White Sugar, Citric Acid (Food Acids), acidity l t ( l d lt l t ) S di B t (P ti )regulator (glucono-delta-lacton), Sodium Benzoate (Preservatives)

Page 28: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Basmati Rice with Algae Record ID: 1593810 Company: Laboratorios AlmondBrand: NaturGreenCategory: Side Dishes Sub-Category: Rice Country: Spain Store Name: HipercorStore Name: HipercorStore Type: Mass

Merchandise/Hypermarket

Store Address: Pozuelo de Alarc 2822428224

Date Published: Jul 2011 Product source: Shopper Launch Type: New Product Price in local currency: 3.05Price in US Dollars: 4.28Bar Code: 8437011502018

Ingredients: Basmati Rice, Vegetables (Vegetable Based) (Onion, Parsley, Carrot, Tomato, Celery, Garlic), g g ( g ) ( y y )

Algae (Nori, sea spaghetti wakame, Kombu Seaweed), Cassava Starch, Miso (Soybean, Barley, Sea Salts), Salt, Spices (Ginger, Peppers, Coriander, Cumin Seed, Nutmeg, Mace)*from organic farming

Page 29: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

So what has CyberColloids being doing ??

Page 30: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

EU FP7 Project HYYFI €1M 2yrsEU FP7 Project HYYFI, €1M, 2yrsCyberColloids, Reading and Ulster University 3 SME’ S i S tl d d I l d3 SME’s – Spain, Scotland and IrelandFocus is on low molecular weight agar and l i t ithi d ith t th t blalginate within and without the sea vegetable

Colonic model studies in ReadingHuman Intervention Studies in UlsterScale up for SME producer

www.seaweedforhealth.org

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SWAFAX: Seaweed derived antiSWAFAX: Seaweed derived anti-inflammatory agents and antioxidants

P j t Obj tiProject ObjectivesProject is ongoing. RTDs: CyberColloids, U. Ulster, U. j g g y , ,Reading.

Extraction and characterisation of anti-oxidant rich extracts from seaweeds, with an emphasis on phlorotannins (brown seaweed polyphenols).

In vitro analysis of anti oxidant/anti inflammatory activityIn vitro analysis of anti-oxidant/anti-inflammatory activity of extracts.

Investigation of the bioavailabilty/bioactivity of phlorotanninsInvestigation of the bioavailabilty/bioactivity of phlorotannins through a human dietary intervention study.

Transfer of knowledge to SMEs for commercialisation. a s e o o edge to S s o co e c a sat o

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Page 33: Who, Why and What we do Hlth d dHealth and seaweed …EN).pdf · Hlth d dHealth and seaweed Source of nutrition: fact or fiction . ... Sauce with Nori Nori ... Sdi B tSodium Benzoate

Seaweed seen as a ‘nuisance’ not a vegetableSeaweed seen as a nuisance not a vegetableAsian claims mistrustedHow do we access our biomass?How do we access our biomass? Need for proof of sustainability, traceability,

d ff d bilit PLUS O i ?and affordability PLUS Organic?Suitability of aquaculture – in sea vs tanks?

l f dd d l dDevelopment of added value products- extracts vs processed vegetables Prove health benefits to achieve best $$$

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Evolution of Health Care

2000BC – Here eat this root

1000AD Th t t i h th 1000AD –That root is heathen Here say this prayer

1850AD – That prayer is superstitious Here drink this potion

1960AD – That potion is snake oil Here swallow this pillp

1985AD – That pill is ineffectiveHere take this antibioticHere take this antibiotic

2000AD - That antibiotic doesn’t work anymoreHere eat this root

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Thank you for your attentionThank you for your attention

Contact –[email protected]