Why Leave a Legacy When Why Leave a Legacy When You Can Live Your You Can Live Your

Legacy?Legacy?

Actuaries’ estimate of my life expectancy as of my 55th Birthday

Each square represents one month

The ProblemThe Problem

The SolutionThe Solution

Aging is inevitable. Your squares seem to get used up faster each

year…

don’t they?

Paradigm Shift

Maximum Life FoundationMaximum Life Foundation

June 23, 2000June 23, 2000 Manhattan Beach, Calif.Manhattan Beach, Calif. Manhattan “Beach” ProjectManhattan “Beach” Project

– Assemble the world’s leading researchers in a focused effort, much like the World War II ending Manhattan Project. Ours will end suffering and death from aging.

Finally AchievableFinally Achievable Wishful thinking for >6000 YearsWishful thinking for >6000 Years Not revolutionaryNot revolutionary 20112011

– How long will “they” take?How long will “they” take? 2033?2033? 2043?2043? 2053?2053?Will you be part of the last generation to die From aging… or Will you be part of the last generation to die From aging… or

part of the first generationpart of the first generationto enjoy open-ended strength and vitality?to enjoy open-ended strength and vitality?

““Don’t be left behind”Don’t be left behind”

Law of Accelerating ReturnsLaw of Accelerating Returns

Copyright © Raymond Kurzweil 2001

Another ReasonAnother Reason

Exponentially Rapid Convergence of…Exponentially Rapid Convergence of…– BiotechnologyBiotechnology– Information TechnologyInformation Technology

The intersection of biotech and The intersection of biotech and infotech makes life extension research infotech makes life extension research subject to the Law of Accelerating subject to the Law of Accelerating ReturnsReturns

– NanotechnologyNanotechnologyGoing beyond the limitations of biologyGoing beyond the limitations of biology

Healthful IndustryHealthful Industry

Many popular investments may be ruining our health and shortening our lives

Fast Foods Processed Foods

Alcoholic and Soft Drinks Tobacco

Doesn’t it make sense to commit a portion of our Doesn’t it make sense to commit a portion of our portfolio to investments that cure diseases, promoteportfolio to investments that cure diseases, promote wellness and extend healthy life?wellness and extend healthy life?

What’s Getting Funded?What’s Getting Funded?

Venture capital has slowed dramaticallyVenture capital has slowed dramatically– And only about 5% of biotech VC goes to And only about 5% of biotech VC goes to

start-upsstart-ups IPO’s have dried upIPO’s have dried up Basic research primarily university and/or Basic research primarily university and/or

government supportedgovernment supported– Little applied research for aging Little applied research for aging

interventionintervention– Mostly age managementMostly age management

How about CURE… instead of CARE?

Free Market vs GovernmentFree Market vs Government Stem CellsStem Cells GenomicsGenomics Drug DevelopmentDrug Development NutraceuticalsNutraceuticals NanotechnologyNanotechnology AIAI

TelecommunicationsTelecommunications InfotechInfotech

Intervention is the Problem… not the SolutionIntervention is the Problem… not the Solution

How Long Will This Take… and How Long Will This Take… and How Much Will It Cost?How Much Will It Cost?

TechnologyTechnology TimelineTimeline BudgetBudget

Telomerase/Cell Senescence Telomerase/Cell Senescence 3 Years/7-123 Years/7-12 $60M$60M

CR Mimetics CR Mimetics 2 Years2 Years $15M$15M

Genomics/Molecular Genetics Genomics/Molecular Genetics —— ——

Immune System Restoration Immune System Restoration 2 Years2 Years $2M$2M

Regenerative Medicine/Stem Cells Regenerative Medicine/Stem Cells 3 Years3 Years $20M$20M

Tissue/Organ Storage Tissue/Organ Storage 7 Years7 Years $48M$48M

Arresting Dementia Arresting Dementia 2 Years2 Years $7M$7M

Breaking Extracellular Crosslinks Breaking Extracellular Crosslinks 2 Years/8-102 Years/8-10 $6M$6M

Mitochondrial Medicine Mitochondrial Medicine 15 Years15 Years $106M$106M

Artificial General Intelligence Artificial General Intelligence 10 Years10 Years $33M$33M

Nanomedicine Nanomedicine 18 Years18 Years $1.1-2B$1.1-2B

Pristine/Reengineer Human Genome Pristine/Reengineer Human Genome 19 Years19 Years *$500M-3B*$500M-3B

TOTALTOTAL $1.897-5.297B$1.897-5.297B

SENS SENS 8 Years/14-198 Years/14-19 $1B$1B

We Don’t Need to Cure Aging We Don’t Need to Cure Aging SinglehandedlySinglehandedly

Push healthspan outPush healthspan out– Healthy aging Healthy aging

Pull timeline inPull timeline in Longevity Escape VelocityLongevity Escape Velocity Full court press on low hanging Full court press on low hanging

fruitfruit Funding base for longer-term Funding base for longer-term

projectsprojects

How Long Will This Take… and How Long Will This Take… and How Much Will It Cost?How Much Will It Cost?TechnologyTechnology TimelineTimeline BudgetBudget

CR Mimetics CR Mimetics 2 Years2 Years $5M$5M

Genomics/Molecular Genetics Genomics/Molecular Genetics 1 Year1 Year $2M$2M

Immune System Restoration Immune System Restoration 2 Years2 Years $2M$2M

Pristine Stem Cells Pristine Stem Cells 3 Years3 Years $4M$4M

Arresting Dementia Arresting Dementia 2 Years2 Years $7M$7M

Breaking Extracellular Breaking Extracellular Crosslinks Crosslinks

2 Years2 Years $6M$6M

Artificial General Intelligence Artificial General Intelligence 10 Years10 Years $33M$33M

Nanomedicine Nanomedicine 4 Years4 Years $6M$6M

TOTAL TOTAL $65M$65M

How Much to Lay the Foundation?How Much to Lay the Foundation?

Technology Technology TimelineTimeline BudgetBudget

CR Mimetics CR Mimetics 1 Year1 Year $2M$2M

Genomics/Molecular Genetics Genomics/Molecular Genetics 1 Year1 Year $2M$2M

Immune System Restoration Immune System Restoration 2 Years2 Years $2M$2M

Pristine Stem Cells Pristine Stem Cells 2 Years2 Years $2M$2M

Arresting Dementia Arresting Dementia 1 Year1 Year $.5M$.5M

Breaking Extracellular Breaking Extracellular Crosslinks Crosslinks

2 Years2 Years $6M$6M

Artificial General Intelligence Artificial General Intelligence 3 Years3 Years $4M$4M

Nanomedicine Nanomedicine 2 Years2 Years $1.5M$1.5M

TOTALTOTAL $19.5M$19.5M

Greta Blackburn,health, fitness pioneer

Ray Kurzweil, author, inventor, futurist

John Paul DeJoria,co-founder Paul Mitchell, philanthropist

Aubrey de Grey, PhD, gerontologist, SENS

David Kekich, founder, longevity leader

Funding StrategiesFunding Strategies DonationsDonations Private EquityPrivate Equity

– Age Reversal, IncAge Reversal, Inc– Manhattan Beach Project, LPManhattan Beach Project, LP

IPOIPO – Age Reversal, IncAge Reversal, Inc

Asset Preservation (Endowment)Asset Preservation (Endowment)– Asset ProvidersAsset Providers– Fund ManagersFund Managers

Our ObjectivesOur Objectives

FundingFunding Demonstrate CapabilityDemonstrate Capability Open floodgatesOpen floodgates

Reach Longevity Escape VelocityReach Longevity Escape Velocity– Pull all stops for 14 years Pull all stops for 14 years

Smart, Strong and Sexy at 100… and Smart, Strong and Sexy at 100… and BeyondBeyond– Why not have life Why not have life beginbegin at 100? at 100?

Manhattan Beach ProjectManhattan Beach Project

Concerted effort to pull all the Concerted effort to pull all the pieces togetherpieces together– Focused we live better and longer, Focused we live better and longer,

scattered we will be distant scattered we will be distant memories.memories.

Stop aging by 2029Stop aging by 2029 Demonstrate age-transformation Demonstrate age-transformation

capability in humans by 2033…capability in humans by 2033… … … then beyondthen beyond

Manhattan Beach ProjectManhattan Beach Project

Preserve Life… Our Most Precious Natural ResourcePreserve Life… Our Most Precious Natural Resource

Manhattan Beach, CaliforniaManhattan Beach, CaliforniaMaximum Life Foundation. 949-706-2468Maximum Life Foundation. 949-706-2468

MaxLife.orgMaxLife.orgManhattanBeachProject.comManhattanBeachProject.com