Winthrop Prof. Paul Abbott

Director of Postgraduate Studies & Research

School of Dentistryand the

Oral Health Centre of WA

Isolating Epithelial Cells of Malassez for Therapeutic

Analysis

Marisa de Pinho Background: Epithelial cells are notoriously very difficult to grow

– need to enhance this growth

Aim is to isolate, cultivate and purify epithelial cells of Malassez from human PDL fibroblasts

Mediums to be investigated: EpiLife® (Invitrogen) – human epithelial cell medium Keratinocyte-SFM® (Invitrogen) – keratinocyte serum free medium KBM-Gold® (Lonza) – keratinocyte cell basal media MCB® – specific epithelial cell of Malassez medium

Assoc. Prof. Tony Phan

Tissue Engineering & Regeneration

Fa-Ming Chen, Yan Jin. Tissue Engineering Part B: Reviews. April 2010, 16(2): 219-255.

The SLURP family of Proteins

Secreted mammalian Ly-6/Urokinase-type plasminogen activator receptor-Related Protein

Lymphocyte Antigen 6 (Ly-6) Superfamily

Function:

cellular differentiation

cell growth

cell survival

motility

Glycosylphosphatidylinositol

(GPI) -membrane linked

Flexcell System

Vacuum pumpFlexcell CPU

Dr Danny Yang - PhD student

Tissue Regeneration in Oral Health:

The effect of NGF and EGF on periodontal and

pulp healing of replanted molars in a rat model

Dr Estabelle Ang - Postdoc. Fellow

Autotransplantation of Teeth

Premolar Incisor site

Winthrop Prof. Paul Abbott

Managing Bone Resorption and

External Inflammatory Root Resorption

Winthrop Prof. Paul Abbott

On referral 1 yr - Ca(OH)2 3 mths - Led. 6 mths - Led.

Using Endodontic Medicaments to Treat Root Resorption

Winthrop Prof. Paul Abbott

Pre-operative RCF - 15 mths 4 yrs - Review

Investigations into the Use

of Interim Restorations

During Endodontic

TreatmentJensen A-L, Heffer RM, Hsu H-S, Abbott PV.

Graduate Endodontic Program

School of Dentistry

University of Western Australia

Willytec Chewing Simulator

Willytec Chewing Simulator

+ Dye

Results

Structural Integrity

Group Intact Debonded

GIC 10 15 (60%)

Band 25 0

During mastication - 2 Bacteria + Dye - 1 Dye only - 1

During de-mounting - 1 Dye only - 1

During access cavity

prepn to test CW - 12 Bacteria + Dye - 1 Bacteria only - 3 Dye only - 2 Neither - 6

I. DEVELOPMENT OF FUNCTIONALLY-GRADED DENTAL BIOMATERIALS

Prof. Paul Ichim in collaboration with W/Prof. Xiaozhi Hu (Mechanical Engineering, UWA) ARC Discovery grant 2011-2013 “Development of a hydroxyapatite-containing ceramic composite core dental implant system with effective variable elastic properties”

II. DEVELOPMENT OF A NEW ENDODONTIC POST SYSTEM

Prof. Paul Ichim in collaboration with Dr. Patrick Schmidlin (Faculty of Dentistry, Zurich). This project is funded by Ada Bartholomew research grant.

III. DEVELOPMENT OF AN INDIRECT ASESSMENT OF CLINICAL COMPETENCY OF DENTAL STUDENTS

Prof. Paul Ichim, A/Prof. Jennifer Bazen and W/Prof. Andrew Smith. External partners: School of Dentistry, University of Minessota. The project aims at delivering a competency-based clinical assessment in which the student performance is determined longitudinally by measuring the time spent by the faculty in assisting the student.

Assoc. Prof. Mithran Goonewardene

Orthodontics Group

Histomorphometric Analysis of Bone Surrounding Loaded Microimplants

Dr Angela Pathmanathan

Aims:

1. To assess the changes in bone surrounding self-threaded and self-tapping implants over time.

2. To assess which implants have a more effective response that can be used during orthodontics to achieve ideal movement of teeth over a shorter time period. 

Cephalometric investigation assessing the skeletal stability following Orthognathic Surgical Rotation of the Occlusal Plane

Dr Rob Hamilton

Manipulation of Occlusal Plane

AIMCephalometric investigation of the skeletal

stability following orthognathic surgical treatment involving:

Clockwise Counter-clockwiseNo-rotation

Orthodontic Treatment Effects of Rapid Maxillary Expansion

Appliances and Facemasks on Class 3 Patients

Student: Dr Chris Duigou

Aims: 1. To investigate the treatment effects of using rapid

maxillary expansion devices and facemasks on Class 3 patients.

2. To investigate candidate gene assessment to predict treatment response

The Value of Digital Model Diagnostic Set-up in Treatment

Planning Complex Interdisciplinary Treatment Cases.

Roy GoonewardeneMike Razza

Mithran GoonewardeneKevin Murray

The value of a diagnostic set-up in treatment planning is generally acknowledged yet this has not been scientifically tested.

Aim:To compare the efficacy of using both plaster and digital diagnostic casts for presentation of complex treatment plans to a group of restorative dentists.

Moreover, the acceptability and value of using firstly a wax and plaster diagnostic set-up and secondly, digital models and setup will be evaluated.

Relate years as a dentist/ IT familiarity and usage

+

Repeat in Digital Format (on laptop computer)

Paper/Film/Plaster

Plaster/Wax setup

School of Dentistry

1. Dental Public Health

2. Dental Traumatology

3. Education & Assessment

4. Simulation Teaching

5. Endodontics

6. Materials Science

Main Research Fields

7. Periodontics

8. Oral Cancer

9. Oral Medicine & Oral Pathology

10. Orthodontics

11. Oral & Maxillofacial Surgery

12. Tissue Regeneration and Auto-transplantation