XXIIIth International Congress Phytopharm 2019 · 16.20-16.40 - Dr. Abdelhameed Elameen, Norwegian Institute of Bioeconomy Research, Hoghskoleveien (Norway): “First draft of the

23th International Congress PHYTOPHARM 2019 Saint-Petersburg, Russia, 1-3 July, 2019

XXIIIth International Congress "Phytopharm 2019"

July 1 - 3, 2019 Saint-Petersburg, Russia

www.phytopharm.pro

http://www.phytopharm2018.ch/


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CONGRESS VENUE Administration of Petrogradsky district Bolshaya Monetnaya ulitsa, 19 https://www.gov.spb.ru/gov/terr/reg_petrograd/ How to get there from Metro Petrogradskaya

How to get there from Metro Gorkovskaya

https://www.gov.spb.ru/gov/terr/reg_petrograd/


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EVENT SPONSORS AND PARTNERS

The following partners and supporters of the congress are very much acknowledged:

MAIN EVENT SPONSOR

Sponsors and Exhibitors

EVENT Partners


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WELCOME

Dear participants, dear colleagues!

As the two chairs of the Organizing Committee from Russia of the 23th International Congress PHYTOPHARM 2019, we are pleased to welcome you to saint-Peptersburg! Ever since the first Phytopharm conference in 1990, it has become one of the important events of the year in Phytopharmaceutical Science, aiming to present interesting, state-of-the-art research relevant to professionals working in various fields of herbal medicinal plants and natural product research, and to foster networking and collaboration across the globe and building bridges between East and West. This year, participants from 23 countries, have accepted our invitation and have come to Russia. The scientific program of PHYTOPHARM covers natural product research from phytochemical studies, safety, efficacy and quality aspects until phytotherapeutic and other health related applications. The aim of the congress is to serve as a forum for discussions on trends, and the latest results, and to exchange ideas relating to phytochemical analysis, ethnopharmacology, natural product research, Traditional Chinese Medicine, pharmacology and clinical trials of natural products as well as biotechnology. In total, 79 posters, 12 plenary, and 37 short lectures will be presented during the three days of the congress. In addition to plenary lectures – 6 parallel sessions will allow an appreciable number of participants to present results in oral talks – featuring one special young research session each day. The poster sessions at central time frames within the congress will also provide an opportunity for scientific discussions. The posters are displayed throughout the whole conference. Many people have contributed in the preparation and the organization of this congress. Especially, we want to thank the members of the local organizing committee as well as many team members from St. Petersburg Institute of Pharmacy and Chemical Pharmaceutical University, St. Petersburg, Russia for their great engagement. Also, the members of the scientific committee are highly acknowledged. Special thanks go to our supporters and exhibitors for their financial contribution.

Prof. Valery Makarov Prof. Igor Narkevich Institute of Pharmacy, Saint-Petersburg State Cjemical Pharmaceutical St. Petersburg, Russia University


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ORGANISATION

Organizers St-Petersburg Institute of Pharmacy, Russia

Chemical Pharmaceutical University, St. Petersburg, Russia

FRC of Nutrition, Biotechnology and safety of food, Moscow, Russia

Society for Medicinal Plant and Natural Product Research (GA)

Phytochemical Society of Europe (PSE)

Organizing Committee Prof. E. Flisyuk, St. Petersburg, Russia Prof. V. Makarov, St. Petersburg, Russia Prof. M. Makarova, St. Petersburg, Russia Prof. I. Narkevich, St. Petersburg, Russia Prof. A. Shikov, St. Petersburg, Russia Dr. I . Ampilogova, St. Petersburg, Russia Dr. V. Luzhanin, St. Petersburg, RU Dr. O. Pozharitskaya, St. Petersburg, Russia

Scientific Committee

Prof. R. Bauer, Graz, Austria Prof. V. Verpoorte, Leiden, NL Prof. A.-R. Bilia, Florence, Italy Prof. P. Shabanov, St. Petersburg, RU Prof. D.A. Guo, Shanghai, China Prof. K. Eller, Moscow, RU Prof. M. Heinrich, London, UK Prof. A. Shikov, St. Petersburg, RU Prof. V. Poroikov, Moscow, RU PD Dr. G. Ulrich-Merzenich, Bonn, DE Prof. V. Makarov, St. Petersburg, RU Prof. V. Tutelyan, Moscow, RU Prof. I. Narkevich, St. Petersburg, RU Prof. J-L. Wolfender, Geneve, CH Prof. J. Novak, Vienna, Austria Dr. E. Wolfram, Wädenswil, CH


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REGISTRATION & INSTRUCTIONS

Registration and information desk opening hours:

Monday, July 1, 2019 8:15 - 18:00 Tuesday, July 2, 2019 8:15 - 16:30

Instructions for... ... oral contributions The duration of lectures include 5 min for discussion. For oral presentations, the following equipment is available: PC (windows based), beamer (single projection). Please upload your presentation at the registration desk as soon as you arrive.

... poster contributions There will be two poster sessions. Please check the list of posters. Posters # 1-40 should be presented on July 1, 9:00 until 18:00h. Posters # 41-79 should be presented on July 2, 9:00 until 16:00h. The size of the posters should be 84 x 119 cm (DIN A0) or 33 inch x 45 inch, respectively (width x height). Participants are responsible for mounting their posters on the numbered poster stands according to the list starting p. 16 and are responsible to remove them. You find the pins on the poster stands – only mount your poster on the stand with the assigned number.

... poster awards – only if authors are present at closing ceremony

Phytopharm 2019 Poster Award

The Scientific Committee will recognize outstanding posters presented by Congress participants. Awards will be made for quality of research design and quality of the poster layout on behalf of the Phytochemical Society of Europe. The authors of the best posters will be granted with the award during the closing ceremony on July 2, 2019. The award will be delivered only to one of the authors personally.


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PROGRAM

Monday, July 1, 2019 08.15 - Registration, mounting of posters and exhibition

(lobby)

09.00-11.00 - Plenary session (Hall A)

Chairs – Prof. Valery Makarov, Prof. Igor Narkevich

09.30-10.00 - Prof. Anna-Rita Bilia, President of GA, University of

Florence (Italy): "Natural products: strategies to cross

biological barriers?"

10.00-10.30 - Prof. Rudolf Bauer, University of Graz (Austria):

“Strategies for a more holistic approach in the quality

control of herbal medicinal products”

10.30-11.00 - Prof. Alexander Shikov, Saint-Petersburg Institute of

Pharmacy (Russia): “Animal-derived medicinal products

in Russia: their history and applications”

11.00-11.05 - Ms. Yulia Kisrchner, Max Zeller Söhne AG

(Switzerland)

11.05-11.30

09.00-09.30 - Opening of the Conference Prof. Valery Makarov

(Chief Organizer) and Prof. Igor Narkevich

Welcome notes by:

Prof. Anna-Rita Bilia, President of GA, University of

Florence, Italy

Prof. K. Eller, Institute of Nutrition, Moscow, Russia

Dr. Evelyn Wolfram, PSE, Switzerland

Prof. Konstantin Eller, Federal Research Centre of

Nutrition and Biotechnology, Moscow, Russia

supported by


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Chair –Prof. Anna-Rita Bilia

11.30-12.00 - Prof. Dr. Michael A. Popp, Bionorica SE, Neumarkt (Germany): “Generics from evidence-based phytomedicines are not possible”

12.00-12.30 - Prof. Vladimir Poroikov, Institute of Biomedical

Chemistry, Moscow (Russia):“In Silico Estimation of

the Hidden Pharmacological Potential of Natural

Products”

12.30-13.00 - Prof. Michael Heinrich, University of London (UK): “Can medicine be a food? Scientific challenges with dietary supplements and herbal medicinal”

13.00-14.00 - Poster session (part 1) and

Lunch Break with Exhibition (authors should be present at their posters) (lobby)

14.00-15.50 - Plenary session and presentation of sponsors

(Hall A)

Chair – Prof. Rudolf Bauer

14.00-14.30 - Prof. Rob Verpoorte, Institute of Biology Leiden (The

Netherlands): “Synergy: easy to say, difficult to prove”

14.30-15.00 - Prof. Jean-Luc Wolfender, University of Geneva

(Switzerland): “Combined MS and NMR profiling

strategies for a comprehensive survey of herbal medicine

composition – current status and future prospects”

15.00-15.30 - Dr. Evelyn Wolfram, ZHAW, Waedenswill

(Switzerland): “HPTLC and Bioautography –

Opportunities and Limitations in Medicinal Plant

Research and Quality Assessment”

15.30-15.50 - Ms. Natalia Kolesnikova, Mosfarma, Moscow (Russia):

MosFarma: “Knowledge and experience for a Healthy

Future”

15.50-16.20


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Hall A, Chair – Prof. Michael Heinrich 16.20-16.40 – Prof. Konstantin Eller, Institute of Nutrition,

Moscow (Russia): “Dietary supplements and drugs of plant origin: composition, registration, efficacy and health claims”

16.40-17.00 – Prof. Ioanna Chinou, National and Kapodistrian University of Athens (Greece): «Health claims vs medicinal indications for herbal products in EU. An up-to-date scientific view»

17.00-17.20 – Dr. Bernd Roether, Bionorica SE, Neumarkt (Germany): “Comparison of regulatory systems: EU and EAEU”

17.20-17.40 – Dr. Kelber Olaf, Steigerwald Arzneimittelwerk GmbH, Bayer Consumer Health(Germany): “Herbal medicinal products versus botanicals in functional gastrointestinal diseases: Epidemiological data from the PhytoVIS project”

17.40-18.00 – Ms. Anna Sukhanova, First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow (Russia): “Determination of sibutramine in drugs and anorexigenic dietary supplements of plant origin”

Chair – Prof. Jean-Luc Wolfender

16.20-16.40 - Dr. Abdelhameed Elameen, Norwegian Institute of Bioeconomy Research, Hoghskoleveien (Norway): “First draft of the genome sequence of the adaptogen medicinal plant roseroot (Rhodiola rosea)”

16.20-18.00 - Session 2 " Quality assurance and control and manufacturing technology of natural products "(Hall B)

16.20-18.00 - Session 1 " Regulation of herbal medicinal products and

food supplements in Russia and European Union"

(Hall A)


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16.40-17.00 - Dr. Vasiliy Vasil’ev, RUDN University, Moscow (Russia): " Flavonoids with an intramolecular hydrogen bond: classification by position of 5-OH groups signals in 1H NMR spectra "

17.00-17.20 - Dr. Vladimir Ulogov, LTD “CLL”, Moscow (Russia):

“Standardization of HPTLC methods for herbal drugs and

dietary supplements” 17.20-17.40 - Dr. Mette Goul Thomsen, Norwegian Institute of

Bioeconomy Research, Hoghskoleveien (Norway): "Abiotic and biotic factors affecting yield and quality of Rhodiola rosea L."

17.40-18.00 - Mr. Andrey Whaley, Saint-Petersburg State Chemical and Pharmaceutical University, Saint-Petersburg (Russia): “Phytochemical analysis of the flavonoids contained in the leaves of Rubus chamaemorus L.”

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- 18.30-19.30 – Welcome Reception

Restaurant “U Gorchakova”

Bolshaya Monetnaya, 19


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Tuesday, July 2, 2019


Chair – Prof. Rob. Verpoorte

09.00-09.30 - Prof. Petr Shabanov, Institute of Experimental Medicine

St. Petersburg (Russia): “Pharmacology of ghrelin peptide

system”

09.30-10.00 - Prof. Maria Povydysh, Saint-Petersburg State

Chemical and Pharmaceutical University, Saint-Petersburg (Russia): “Role of metabolomics in medicinal plant analysis”

10.00-10.30

- PD Dr. rer. nat. Gudrun Ulrich-Merzenich, Universitätsklinikum Bonn (Germany): “Synergy quantification to identify individual contributions of combination partners”

10.30-11.00

11.00-13.00 - Session 3 " Advances in drug discovery and clinical studies in phytotherapy and natural products based drugs " (Hall A)

Chair – Prof. Petr Shabanov

11.00-11.20 - Dr. Dimitri Abramov-Sommariva, Bionorica SE (Germany): “New clinical trial with the herbal drug Canephron® N (BNO 1045) supporting the change of paradigm in urology”

11.20-11.40 - Dr. Konstantia Graikoua, National & Kapodistrian University of Athens (Greece): “Phenolic metabolites of six greek endemic boraginaceae species - biological evaluation”

supported by


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11.40-12.00 - Mr. Umit Toktas, Ege University, Izmir (Turkey):

“Phytochemical Studies on Galium asparagifolium”

12.00-12.15 - Ms. Sophia Gerontakos, Endeavour College of Natural

Health (Australia): “Defining and Measuring the

Naturopathic concept ‘Adaptogen’: a qualitative study”

12.15-12.30 - Ms. Ksenia Evstigneeva, Saint-Petersburg State Chemical and Pharmaceutical University, Saint-Petersburg (Russia): “The analysis of the antimicrobial action of essential oils”

12.30-12.45 - Ms. Adriana Trifan, Grigore T. Popa University of Medicine and Pharmacy Iasi (Romania): “Brown algae from Romanian Black Sea as sources of bioactive compounds. The case of Cystoseira barbata (Stackhouse) C. Agardh”

12.45-13.00 - Discussion

13.00-14.00 - Poster session (part 2) and Lunch Break (authors should be present at their posters) (lobby)

11.00-13.00 - Session 4 " Ethnopharmacology " (Hall B)

Chair – PD Dr. rer. nat. Gudrun Ulrich-Merzenich

11.00-11.20 - Prof. Yan Ma, Medical University of Vienna (Austria): “Anti-tumor activities of panax quinquefolius saponins and their possible mechanism in prostate cancer”

11.20-11.40 - Dr. Ipek Suntar, Gazi University (Turkey): «The Beneficial Effects of Cornus mas L. in Ameliorating Rat Model of Ulcerative Colitis»


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11.40-12.00

12.00-12.15

12.15-12.30

-

-

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Dr. Kenny Kuchta, University Medical Center Göttingen (Germany): " Standardized Japanese Kampo extracts and their effects on human and murine pancreatic cancer cells " Ms. Lisa-Anna-Maria Pihan, Zurich University of Applied Sciences, Wädenswil (Switzerland): “Antiviral and Bioautographic Antioxidativ, Östrogenic and AchE-inhibitoric Activity of Ethanolic Extracts of Different Sideritis Species” Mr. Rahul Sharma, Pondicherry Central University (India): «Isolation, Purification and Structural Characterization of Major N-alkylamides from Spilanthes ciliate»

12.30-12.45 - Ms. Nurdan Yazıcı Bektaş, Istanbul University (Turkey): “Antidiabetic, Acetylcholinesterase Inhibitor and Cytotoxic Activites of the Root Extracts of Ferula mervynii” 12.45-13.00

-

Mr. Timo A. Thumann, University of Graz (Austria): “Fermentation of STW-5 with human faces to investigate metagenomic changes of gut bacterial populations and metabolization of its constituents”

14.00-16.00 - Session 6 "Medicinal plant and natural medicinal

products: challenges, formulations and efficacy"

(Hall A)

Chairman – Dr. Evelyn Wolfram

14.00-14.20 - Dr. Jan Seibel, Bionorica SE (Germany): “Building up Evidence from Bedside to Bench: The Bronchipret® Story”

14.20-14.40 - Dr. Andrea Baier, Zurich University of Applied Sciences (Switzerland): “Corn Storage Protein Zein: a plant based Biopolymer for Drug Delivery Systems”

14.40-15.00 - Mr. Dmitry Bokov, Sechenov University, Moscow (Russia): «Creation of a medicinal plants genetic seed bank as a basis for import substitution of medicinal raw materials within the framework of Pharma-2030”


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15.00-15.20 - Ms. Julie Carette, University of Mons (Belgium): “Characterizing the biofilm architecture of P. aeruginosa and his mutants as a clue to develop new anti-infectious strategies”

15.20-15.40 - Ms. Darya Nekrasova, Saint-Petersburg State Chemical and Pharmaceutical University, Saint-Petersburg (Russia): “Clonal micropropagation of Melilotus officinalis L. and Melilotus hirsutus Lipsky”

15.40-16.00 - Ms. Anna Raysyan, Bundesanstalt für Materialforschung und -prüfung (BAM), Berlin (Germany): “Flow-through membrane-based enzyme immunoassay and fluorescence polarization immunoassay (FPIA) of AFB1 for quality assessment of pharmaceutical substances and medical herbs”

14.00-16.00 - Session 6 "Korean ginseng and its beneficial efficacy" (Hall B)

Chairman – Prof. Jae Youl Cho 14.00-14.15 - Prof. Dong-Kwon Rhee, Sungkyunkwan University (South

Korea): "Korean red ginseng and stress-induced diseases"

14.15-14.30 - Prof. Si-Kwan Kim, Konkuk University, Chungbuk Chungju (Republic of Korea): "Korean red ginseng attenuates anti-cancer agent-induced testicular damages in rats"

14.30-14.45 Prof. Seikwan Oh, Ewha Womans University, Seoul (South Korea): "Ameliorating effect of ginseng on memory decline"

14.45-15.00 Prof. Man Hee Rhee, Kyungpook National university, Daegu (Republic of Korea): "Anti-inflammatory effects of Rg3-enriched red ginseng extract from Korean red ginseng"

15.00-15.15 Prof. Jong-Hoon Kim, Chonbuk National University, Iksan-

city, Jeollabuk-Do (Republic of Korea): "Animal modeling for

osteoarthritis and the effectiveness of ginsenosides Rb1,

compound of Korean red ginseng "

15.15-15.30 Prof. Jae Youl Cho, Sungkyunkwan University, Suwon,

(Republic of Korea):"Korean ginseng as promising

immunomodulatory herb"


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15.30-15.45 Dr. Byungcheol Han, Korea Ginseng Research Institute,

Daejeon (Republic of Korea): "Korean red ginseng as a

traditional herbal plant and its efficacy"

15.45-16.00 Group discussion

16.00-16.20

16.20-16.50

- Poster Awards and Closing Ceremony (Hall A)

19.00-22.00

Congress Dinner At Parkking

(“Imperatorhall”) Aleksandrovsky park, 4


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POSTER PRESENTATIONS

Part 1: posters #1-40

July 1, 2019 (13.00-14.00) No. Authors Title

1. Aroyan M.V., Irtegova A.O., Kaukhova I.E The development of the composition of the gel based on dry extract of the Melilotus officinalis L.

2. Belokurov S.S., Alekseeva V.A., Novikova K.O., Flisyuk E.V.

Comparative analysis of extraction methods of chicory

3. Anna Benea, Igor Casian, Vladimir Valica, Nicolae Ciobanu, Maria Cojocaru-Toma, Cristina Ciobanu

Bioactive compounds of the aerial parts of hypericum species from republic of Moldova

4. Kieron Edwards, Carla Russo, John Clapham, Inger Larsen, Mohammed Zaibi, Mariia Chetyrkina

Supporting Cognitive Performance with Salvia officinalis (S. Officinalis)

5. Ira Kagkiouzi-Podbielski, Aimilia Rigakou, Eleni Melliou, Ioanna Chinou, Prokopios Magiatis

Quantitative NMR study of the major metabolites in herbal teas produced from six Sideritis species growing in Greece

6. Christos Ganos, Gokhan Zengin, Konstantia Graikou, Nikolas Fokialakis, Tomasz Mroczek, Ioanna Chinou

LC-MS phenolic profile of three Alkanna species growing in Turkey - biological properties

7. Jong Hee Choi, Minhee Jang, Joon-Il Lee, Won-Seok Chung and Ik-Hyun Cho

Korean herbal medicine Kyung-Ok-Ko protects nigrostriatal dopaminergic neurons from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice

8. Maria Cojocaru-Toma, Robert Ancuceanu, Mihaela Dinu, Nicolae Ciobanu, Cristina Ciobanu, Anna Benea, Sergiu Parii, Valentin Gudumac, Valeriana Pantea, Maria-Mirabela Toma

Acute Toxicity And Hepatoprotective Action For Extracts Of Some Species Cultivated In The Republic Of Moldova

9. Chatsri Deachapunya, Wannaporn Chayalak, Sunit Suksamrarn, Sutthasinee Poonyachoti

Enhancement of tight junctional barrier function during physiological condition and inflammation by hydroxyxanthones: effects on tight junction remodeling

10. Nina Djapic, Mihailo Ristic

Vitis vinifera var. White Riesling Chemical Profile Obtained by Different Extraction Procedures

11. Branko Filipović, Branka Šošić-Jurjević, Nataša Nestorović, Nataša Ristić, Svetlana Trifunović, Fedor Filipović, Verica Milošević

The effects of soybean phytoestrogens on trabecular bone microarchitecture and biochemical parameters of bone turnover in middle-aged male rats

12. P. Fyhrquist, R. Julkunen-Tiitto, H. Vuorela, E.Y.A. Salih, S. Hämäläinen

Prenylated indole alkaloids and benzoate derivatives in antibacterial extracts of Friesodielsia obovata Verdc. and Hexalobus monopetalus Engl. & Diels

13. E. Salih, M. Kanninen, O. Luukkanen, H. Vuorela , P. Fyhrquist

Antibacterial potential of the Rubiaceae species Xeromphis nilotica (Stapf) Keay and Gardenia lutea Fresen

14. Alekseeva G.M., Generalova Yu.E, Dikova L.S., Luzhanin V.G.

Quality control of medicinal plants using capillary electrophoresis


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15. Dimitris Pentafragasa, Maroula G. Kokotoub, Tomasz Mroczekc, Ioanna Chinoua, Konstantia Graikoua

Metabolic profiling of traditional herbal teas of Cistus Creticus from Crete and Lesvos islands – biological properties

16. Konstantia Graikou, Argyro Petropoulou, Jaroslaw Widelski, Krystyna Skalicka-Woźniak, Zuriyadda Sakipova, Ioanna Chinou

Chemical composition of selected eurasian propolis samples

17. Gudkova A.A., Chistyakova A.S., Kuznetsov A.Yu.

Using the microscopic analysis to identify closely related species of the genus Persicaria Mill.

18. Gudkova A.A., Buzlama A.V., Slivkin A.I. Preclinical studies of pharmacological activity of Persicaria maculosa herb extract

19. Sun Tae Hwang, Jong Hyun Lee, Jeong‐Hyeon Ko, Kwang Seok Ahn, Seok‐Geun Lee

Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells

20. In Ho Jung, Haneul Kim, Hye Min Kim, Ho Jung Bae, Jun Hee Jang, Dong Hyun Kim, Jong Hoon Ryu

The alleviating effects of ethanol extract of Zizyphus jujuba on synaptic dysfunction via regulating plasmin in 5XFAD, Alzheimer's disease mice model

21. Young Yun Jung, Jeong Hyeon Ko, Jong Hyun Lee, In Jin Ha, and Kwang Seok Ahn

Anti-inflammatory Effects of Pilea martinii (Levl.) Hand.-Mazz. Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

22. Hyun June KIM, Chong Woon CHO, Seo Young YANG, Young Ho KIM and Jong Seong KANG*

Pattern analysis of main components for herbal functional mixture and its composition herbal material with anti-aging activities by HPLC-DAD-ESI-MS

23. Jin Pyo An, Won Keun Oh, Jinwoong Kim

Eudesmane glycosides from Ambrosia artemisiifolia (common ragweed) showed protective effects against Aβ-induced cytotoxicity in Aβ42-transfected HT22 cells

24. Mi Hye Kim, Woong Mo Yang Pharmaceutical study of effect of (R)-(+)-pulegone on atopic contact dermatitis in mice

25. Sunggyu Kim, Eunju Choi , Eunji Kim, Kon Kuk Shin, Yo Han Hong, Han Gyung Kim, Jae Youl Cho

Compound K, a ginsenoside metabolite, plays an anti-inflammatory role in macrophages by targeting the AKT1-mediated signaling pathway

26. Kosman V.M., Faustova N.M., Pozharitskaya O.N., Shikov A.N., Makarov V.G.

Approaches to pharmacokinetics study of natural origin drugs based on biological activity

27. Simone Wöscher, Manfred Coenen, Getu Abraham, Kenny Kuchta

Coriandrum sativum seeds and Aloe vera gel as anti-diabetic agents in dogs

28. Kenny Kuchta, Marie Hladikova, Mathias Schmidt

Under which conditions is kava extract best suited for the treatment of anxiety? Results of an open, observational study

29. Kenny Kuchta, Wolfgang Waser, Silke Cameron, Hans Rausch

Novel Herbal Veterinary Narcotics for Catfish, e.g. Clarias gariepinus Burch.

30. Alexey Kuznetsov, Anna Basevich Study of the qualitative composition of the amount of oregano herb flavonoids by TLC

31. Se Jung Park, Jongsung Lee p44/42 MAPK signaling is a prime target activated by phenylethyl resorcinol in its anti-


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melanogenic action

32. Ara Jo, Ye Eun Lee, Ui Hyeon Im, Mina Lee

Discovery of biflavonoids from medicinal plants against inflammatory bowel disease

33. Boo-Yong Lee, Sungwoo Chei Magnolol inhibits epithelial-mesenchymal transition through downregulation of TGF-β signaling in human colon cancer cell

34. In Jin Ha, Minji Choi, Kwang Seok Ahn and Seok-Geun Lee

Effect of Papaver nudicaule L. on lipopolysaccharide-induced inflammation

35. Ki Sung Kang, Noriko Yamabe, Myoung-Sook Shin, Sullim Lee

Deoxyshikonin enhances wound healing in diabetic mice

36. Chantana Mekseepralard, Weeranuch Seesom, Sudarat Sondonprai, Nirawan Kitprapiumpon, Faongchat Jarintanan, Wanlaya Tanechpongtamb

Antileptospiral Activity of Medicinal Plants and Synergistic Response with Ampicillin

37. Verica Milošević, Branko Filipović, Jasmina Živanović, Marko Miler, Milica Manojlović-Stojanoski, Gordana Ušćebrka, Vladimir Ajdžanović

The effects of Vitex agnus-castus L. essential oil on the pituitary cells in middle aged rats

38. Verónica Taco, Pierre Duez, Claudio Palmieri, Amandine Nachtergael

HPTLC-bioautography for the evaluation of the antioxidant and anti-hyperglycemic activities of natural deep eutectic solvent extracts obtained from quinoa leaves (Chenopodium quinoa Willd)

39. Nguyen Thi Ngan, Kaukhova I.E., Vainshtein V.A., Ivkin D.Yu.

The antihypoxic activity of the composition of phytoextracts of corn silk, achyranthes bidentata and rutin

40. Nguyen Thi Sen, Kaukhova I.E., Sorokin V.V.

Kinetics study on the flavonoid extraction process from trifolium pratense l. using the method of ultrasound extraction

POSTER PRESENTATIONS

Part 2: posters #41-79

July 2, 2019 (13.00-14.00)

No. Authors Title

41. Johanna Möller, Olaf Kelber, Karen Nieber Herbals at the forefront of the treatment of functional GI diseases in children: A systematic review

42. Raskopf E., Möller J, Greinert O., Zadoyan G., Schleicher S., Sha-Hosseini K., Wegener, T, Kelber O., Singh J. , Kraft K., Nieber K, Mösges R.

Phytopharmacotherapy – safe and useful also in children: Data from the PhytoVIS study, a NIS in 20,870 users of herbal medicinal products

43. J. Möller, E. Raskopf, O. Greinert, G. Zadoyan, S. Schleicher, K. Shah-Hosseini, T. Wegener, O. Kelber, J. Singh, R. Mösges, K. Kraft, K. Nieber

A herbal preparation in the treatment of functional gastrointestinal diseases: Epidemiological data from 1515 patients

44. J. Möller, E. Raskopf, O. Greinert, G. Zadoyan, S. Schleicher, K. Shah-Hosseini, O. Kelber, J. Singh, R. Mösges, K. Kraft, K. Nieber

St. John´s wort in a large epidemiological study on the use of herbal medicinal products

45. B. Vinson, S. Skeib, O. Kelber, K. Nieber Herbal medicinal products in the public pharmacy: A surveillance study with STW 5


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in Irritable Bowel Syndrome and other functional GI diseases

46. J. Möller, E. Raskopf, O. Greinert, G Zadoyan, S. Schleicher, K. Shah-Hosseini, T. Wegener, O. Kelber, J. Singh, K. Kraft, K. Nieber, R. Mösges

Althaea officinalis root extract in the light of the PhytoVIS study, a NIS in 20,870 users of herbal medicinal products

47. Olaf Kelber, Johanna Möller, Karen Nieber Althaeae radix: A medicinal plant with a great tradition

48. Nikulin A.V., Potanina O.G., Platonov E.A. Quantum-chemical study of reaction products in determining the reducing sugar amount

49. Yamshchikova S.I., Nikulin A.V., Potanina O.G., Dul V.N., Platonov E.A., Abramovich R.A.

Standardization of spissum extract of lichen genera Cladonia and Cladina

50. Obluchinskaya E.D. The effect of ultrasound-assisted extraction on the kinetics, molecular weight distribution and chemical composition of fucoidan

51. Thi Kim Quy Ha, Ha Thanh Tung Pham and Won-Keun Oh

12,23-Dione dammarane triterpenes from Gynostemma longipes and their muscle cell proliferation activities via activation of the AMPK pathway

52. A. Orlova, M. Povydysh, V. Chantseva, M. Dorn, T. Bilova, A. Frolov

Polyphenolic Compounds of Geum rivale L.

53. Seul Ji Lee, Gyu Hwan Hyun, Yoon Young Yang, Sung Won Kwon, Jeong Hill Park

Advanced Quality Control of Ginseng Using Acidic Polysaccharide as a Marker Compound

54. Paryaeva V.U., Chistyakov K.S. Prospects of using of remote sensing data for determination of content of anthocyans

55. N.S. Pivovarova, O.N. Abrosimova, T.S. Shebitchenco

Composition development and standardization of oral solution based on the biomass of polyscias strains

56. Nasser R.A., Potanina O.G., Nikulin A.V. Development and validation of the free organic acids determination procedure in Portulaca oleracea's aerial parts (Portulaca oleracea L.)

57. Hajjar Fadi, Potanina O.G., Abramovich R.A.

Flavonoids determination in the spissum extract of Polemonium Coeruleum L. herb.

58. José E. Quiroz-Hernandez, Victor E. Aguirre-Arzola, Antonio J. Ruiz-Oribe, Uziel Castillo-Velázquez, Ramiro Quintanilla-Licea

Evaluation of Anti-Quorum sensing and Antimicrobial activity against Gram-negative bacteria of medicinal plants used in Northeast Mexico

59. Tae-Hwan Kim, Muhammad Irfan and Man Hee Rhee

Anti-platelet activity of Ginsenoside-Rp3: Mediated via MAPK and cAMP signaling

60. Rud N.K. The composition choice of the soft gel capsules shell with supercritical carbon-dioxide extract of Nigēlla satīva L. of the buttercup seeds

61. Ho Jung Bae, Yulan Liao, Seo Yun Jung, Jihyun Kim, Jaehoon Kim, Nayeon Goo, Yongwoo Jeong, Jong Hoon Ryu

The effects of Bee pollen on the cholinergic blockade-induced cognitive impairment

62. Ho Jung Bae, In Ho Jung, Seo Yun Jung, Huiyoung Kwon, Jihyun Kim, Jaehoon Kim, Nayeon Goo, Yongwoo Jeong , Dong Hyun Kim, Jong Hoon Ryu

DHP1401 regulates synaptic components of NMDA receptor


Program, page 20

63. Salih Enass, Kanninen Markku, Luukkanen Olavi, Vuorela Heikki, Fyhrquist Pia

Antibacterial potential of the Rubiaceae species Xeromphis nilotica (Stapf) and Gardenia lutea Fresen

64. Jan Seibel, Kirill Kryshen, Martin D. Lehner

Anti-inflammatory, Mucus-normalizing and Cough-soothing Activity of Bronchipret

® Oral

Drops in an in vivo experimental setting

65. Noriko Yamabe, Ki Sung Kang, Sullim Lee, Myoung-Sook Shin

Pectic Polysaccharides isolated from Panax ginseng leaves inhibit tumor metastasis via macrophage and NK-cell activation

66. Novikova E.K., Strelkova A.V., Kaukhova I.E.

Development to technology for inulin production from roots Arctium lappa

67. Suina I.O., Terninko I.I., Pechnikova N.A., Semivelichenko E.D., Toporkova V.I.

Studying the antioxidant activity of Aristolochia Clematitis l. herb dry extracts

68. Suloev I.S., Ponkratova A.O., Teslov L.S., Luzhanin V.G.

The quantification of phenolic compounds in Canadian goldenrod grass (Solidago canadensis L.)

69. Sule Ozel, Ipek Suntar, Nilufer Ercan Gokay, Tugba Taskin Turkmenoglu, Murside Ayse Demirel

Investigating the activity of Teucrium chamaedrys L. in Experimental Rat Endometriosis Model

70. Adriana Trifana, Simon Vlad Luca, Sebastian Opitz, Roland Josuran, Samuel Peter, Sarah Bräm, Nadja Meier, Evelyn Wolfram

Symphytum officinale L. (comfrey) roots - characterization of main phenolic compounds

71. Gudrun Ulrich-Merzenich, Lisa Welslau, Olaf Kelber, Anastasiia Sherbakova, Christiane Esch, Thore Thiesler, Hans Peter Fischer, Glen Kristiansen, A.M. Kassem, Heba Aziz-Kalbhenn

Regulations of ASIC 4, 5-HTR and SERT in the esophageal mucosa under STW5 and omeprazole treatment support a corporate role in pain sensing

72. G. Ulrich-Merzenich, L. Welslau, H. Aziz-Kalbhenn, O. Kelber, A. Shcherbakova

The Identification of individual contributions of combination partners in complex mixtures – the example of STW5

73. Shcherbakova A, Nyugen L, Ulrich-Merzenich G

Lichen extracts with synergistic potential for the treatment of cancer cells

74. I.N. Urakova, A.A. Nikandrova , O.N. Pozharitskaya, A.N. Shikov

Antioxidant activity of bisnaphthazarin in experimental model of cataract ex vivo

75. Vasilii Vasil’ev, Tatyana Shishkina, Gennady Kalabin, Vasilii Ivlev, Rimma Abramovich

Rapid screening of flavonolignans content in Silybum marianum extracts by quantitative 1H NMR spectroscopy (q1НNMR)

76. Thi Phuong Duyen Vu, In Sook Cho, Young Ho Kim, Jong Seong Kang

Differences in phenolics composition between healthy and viroid-infected grapes (Vitis spp.) in Korea

77. Bing Tian Zhao, Duc Dat Le, Da Hye Sim, Si Whan Song, Jong Keun Son, Mi Hee Woo

Discrimination between steamed and Un-steamed Tubers of Gastrodia elata Blume by HPLC

78. Zhokhova E.V., Ditkovskaya Z.R., Balaban L.V.

Elemental composition of the above-ground part of dyer’s greenweed

79. Moritz Zürn, Imre Boldizsár Underground organs of Plantago spp.: new and rich sources for the isolation of valuable phenylethanoid glycosides plantamajoside, isoplantamajoside and acteoside

23th International Congress PHYTOPHARM 2019 Sankt-Petersburg, Russia, 1-3 July, 2019

Program, page 21

Wednesday, July 3, 2019 EXCURSION "Plantation of the State Chemical Pharmaceutical University"

Participation upon registration only – please mark in registration form. The schedule 10.00 am -Departure from St-Petersburg (Prof. Popov, 14, main building of The State Chemical Pharmaceutical University)

11.30 am – arrival to the plantation 12:00-14:00 – guided tour on the plantation 14:00-15:00 – lunch 15:30 – departure to St-Petersburg 17:00 (approximately) – arrival to the city


Program, page 22

Vth Courses "GxP in Biomedical research"

(in Russian only)

V Школа

"GxP в биомедицинских исследованиях"


Program, page 23

Понедельник, 1 июля, 2019

16.20-16.50 - Проф., д.ф.н. Ковалева Е.Л., зам. директора центра

экспертизы и контроля готовых лекарственных средств Центра экспертизы и контроля готовых лекарственных средств ФГБУ "НЦЭСМП" Минздрава России: «Современные требования к оценке качества лекарственных средств»

16.50-17.20 - Проф., к.б.н., Енгалычева Г.Н. Зам. начальника управления экспертизы лекарственных средств Центра экспертизы и контроля готовых лекарственных средств ФГБУ "НЦЭСМП" Минздрава России: "Доклинические исследования безопасности при разработке лекарственных средств для детей"

17.20-17.40 - Проф., д.фарм.н. Флисюк Е.В. Проректор по научной работе СПФХУ, зав. кафедрой технологии лекарственных форм: “Актуальный подход к обучению уполномоченных лиц по качеству ”

17.40-18.00 - Др., к.б.н., Крышень К.Л. Руководитель отдела токсикологии и микробиологии ООО «ИДкИ»: «Подготовка программы доклинических исследований в соответствии с требованиями Евразийской Экномической Комиссии (ЕЭК)»

Вторник, 2 июля, 2019

11.00-13.20

-

Секция B (Холл С)

11.00-11.20 - Проф., д.фарм.н. Раменская Г.В., Директор Института Фармации ПМГМУ им. И.М. Сеченова, Москва, Россия: «Гармонизация требований по обеспечению качества, эффективности и безопасности лекарственных средств»

16.20-18.00 Секция А (Холл С)


Program, page 24

11.20-11.40 - Др., к.б.н., Лужанин В.Г., Проректор по административно-кадровой и воспитательной работе, зав. кафедрой фармакогнозии СПХФУ: “Разработка фармацевтических и пищевых субстанций растительного происхождения в системе многоуровневого цикла СПХФУ ”

11.40-12.00

-

Проф., д.фарм.н. Тернинко И. И., Директор Центра контроля качества лек средств СПХФУ: «Научные направления фитохимического изучения ЛРС с целью дальнейшей стандартизации и доказательной эффективности фитопрепаратов»

12.00-12.20 - Др., к.ф.н., Шигарова Л.В., ведущий научный сотрудник ОНИР СПХФУ: «Системы качества как элемент обеспечения соответствия надлежащим практикам»

12.20-12.40 - Др. Гудкова А.А., Доцент фармацевтического факультета, ВГУ, Россия: "Использование методов микроскопического анализа для идентификации близкородственных видов на примере рода Persicaria Mill."

12.40-13.00

13.00-13.20

-

-

Др., к.ф.н., Ивкин Д.Ю., директор Центра экспериментальной фармакологии СПХФУ, "Элементы надлежащей лабораторной практики в исследованиях специфической активности". Вручение дипломов Лужанин В.Г. Проректор по административно-кадровой и воспитательной работе СПХФУ


Program, page 25

GENERAL INFORMATION

LANGUAGE: The official language of the Congress is English. No simultaneous translation

will be provided.

INTERNET: WLAN will be not available at the area of the Congress venue.

CERTIFICATE OF ATTENDANCE: A certificate of attendance will be given to all registered participants during

registration to the congress.

CANCELLATION POLICY: No refunds. However, another delegate can be nominated as a replacement. BADGES: Congress badges must be visible at all time during the meeting. Local

organizers, staff and speakers can be recognized by their colored name

badges.

VOLTAGE: Electricity in Russia is 220 Volt.

INSURANCE: The Organizing Committee cannot accept any liability. Participants should make

their own arrangements with respect to health, accident and travel insurance.

IMPORTANT LINKS: -Phytopharm 2019 web-site: www.phytopharm.pro

- Visit St-Petersburg tourist information: www.visit-petersburg.ru/en/

- Russian Railway: www.rzd.ru

- Airport Pulkovo: www.pulkovoairport.ru/en/

DISCLAIMER: The congress organizers cannot be held responsible for any loss, theft,

damage or injury to any person or property during the congress, whatever

the cause may be. The liability of persons and enterprises providing means of

transportation or other services, however, remains unaffected. The customer

takes part in all tours and trips at his/her own risk.

http://www.phytopharm2018.ch/

http://www.sbb.ch/


Program, page 26

SOCIAL PROGRAM

GETTING AROUND IN SAINT-PETERSBURG REGION:

Travel within the larger St-Petersburg Area is best done via public

transportation:

NOTES

Welcome Reception - Get-Together

Monday, July 1, 2019, 18:30 - 19:30

Restaurant “U Gorchakova”

Congress Dinner

Tuesday, July 2, 2019, 19:00 - 22:00

At Parkking (“Imperatorhall”)

Aleksandronsky park, 4

Documents

XXIIIth International Congress Phytopharm 2019 · 16.20-16.40 - Dr. Abdelhameed Elameen, Norwegian Institute of Bioeconomy Research, Hoghskoleveien (Norway): “First draft of the