Yeast genome Gazetteer p35-65wiki.yeastgenome.org/images/e/e7/gazetteer.pdfYIR030c DCG1 involved in nitrogen-catabolite metabolism YBR213w MET8 involved in the expression of PAPS reductase

NATURE | VOL 387 | SUPP | 29 MAY 1997 35

gazetteer

Metabolismamino-acid metabolism

aammiinnoo--aacciidd bbiioossyynntthheessiiss

[[OORRFF]] [[GGeennee]] [[EEnnccooddeedd oorr rreellaatteedd pprrootteeiinn]]YHR037w PUT2 1-pyrroline-5-carboxylate dehydrogenaseYDR035w ARO3 2-dehydro-3-deoxyphosphoheptonate

aldolase, phenylalanine-inhibitedYBR249c ARO4 2-dehydro-3-deoxyphosphoheptonate

aldolase, tyrosine-inhibitedYNL104c LEU4 2-isopropylmalalate synthaseYGL009c LEU1 3-isopropylmalate dehydrataseYPR167c MET16 3’-phosphoadenylylsulphate reductaseYGR019w UGA1 4-aminobutyrate aminotransferase (GABA

transaminase)YER091c MET6 5-methyltetrahydropteroyltriglutamate-

homocysteine methyltransferaseYMR108w ILV2 acetolactate synthaseYCL009c ILV6 acetolactate synthase, regulatory subunitYER069w ARG5,6 acetylglutamate kinase and

acetylglutamyl-phosphate reductaseYJL071w ARG2 acetylglutamate synthaseYOL140w ARG8 acetylornithine aminotransferaseYDR234w LYS4 aconitate hydrataseYER086w ILV1 anabolic serine and threonine

dehydratase YDR354w TRP4 anthranilate phosphoribosyltransferaseYER090w TRP2 anthranilate synthase component IYKL211c TRP3 anthranilate synthase component IIYJR109c CPA2 arginine-specific carbamoylphosphate

synthase, large subunitYOR303w CPA1 arginine-specific carbamoylphosphate

synthase, small subunitYOL058w ARG1 argininosuccinate synthetaseYHR018c ARG4 arginosuccinate lyaseYDR127w ARO1 arom pentafunctional enzymeYPR145w ASN1 asparagine synthetaseYGR124w ASN2 asparagine synthetaseYLR027c AAT2 aspartate aminotransferase, cytosolicYKL106w AAT1 aspartate transaminase, mitochondrialYDR158w HOM2 aspartate-semialdehyde dehydrogenaseYFR030w MET10 assimilatory sulphite reductase flavin-

binding subunitYER055c HIS1 ATP phosphoribosyltransferaseYCL018w LEU2 β-isopropyl-malate dehydrogenaseYJR148w TWT2 branched-chain amino acid

aminotransferase, cytosolicYHR208w TWT1 branched-chain amino acid

aminotransferase, mitochondrialYGR204w ADE3 C1-tetrahydrofolate synthase, cytoplasmic

YBR084w MIS1 C1-tetrahydrofolate synthase,mitochondrial

YPR060c ARO7 chorismate mutaseYGL148w ARO2 chorismate synthaseYGR155w CYS4 cystathionine β-synthaseYAL012w CYS3 cystathionine γ-lyaseYER023w PRO3 δ 1-pyrroline-5-carboxylate reductaseYHR068w DYS1 deoxyhypusine synthaseYOR236w DFR1 dihydrofolate reductaseYFL018c LPD1 dihydrolipoamide dehydrogenase YJR016c ILV3 dihydroxy-acid dehydrataseYLR172c DPH5 diphthamide methyltransferaseYKL191w DPH2 diphtheria toxin resistance proteinYOR323c PRO2 γ-glutamyl phosphate reductaseYDR300c PRO1 glutamate 5-kinaseYDL171c GLT1 glutamate synthase (NAPDPH) (GOGAT)YPR035w GLN1 glutamate-ammonia ligaseYBR248c HIS7 glutamine amidotransferase/cyclaseYFR025c HIS2 histidinol phosphataseYIL116w HIS5 histidinol-phosphate aminotransferaseYMR038c LYS7 homocitrate dehydrogenaseYDL182w LYS20 homocitrate synthaseYJR139c HOM6 homoserine dehydrogenaseYHR025w THR1 homoserine kinaseYNL277w MET2 homoserine O-acetyltransferaseYOR202w HIS3 imidazoleglycerol-phosphate dehydrataseYLR355c ILV5 ketol-acid reducto-isomeraseYBR115c LYS2 L-aminoadipate-semialdehyde

dehydrogenase, large subunitYGL154c LYS5 L-aminoadipate-semialdehyde

dehydrogenase, small subunitYER052c HOM3 L-aspartate 4-P-transferaseYLR303w MET25 O-acetylhomoserine sulphydrylaseYLR438w CAR2 ornithine aminotransferaseYJL088w ARG3 ornithine carbamoyltransferaseYCL030c HIS4 phosphoribosyl-AMP

cyclohydrolase/phosphoribosyl-ATPpyrophosphatase/histidinoldehydrogenase

YDR007w TRP1 phosphoribosylanthranilate isomeraseYGR208w SER2 phosphoserine phosphataseYOR184w SER1 phosphoserine transaminaseYNL316c PHA2 prephenate dehydrataseYBR166c TYR1 prephenate dehydrogenase (NADP+)YLR142w PUT1 proline oxidaseYOL064c MET22 protein ser/thr phosphataseYCR054c CTR86 putative threonine biosynthesis pathway

proteinYEL046c GLY1 required for glycine prototrophy in SHMT1

and SHMT2 double mutantYIR034c LYS1 saccharopine dehydrogenaseYNR050c LYS9 saccharopine dehydrogenase (NADP+, L-

glutamate forming)

YCL009c similarity to acetolactate synthase III smallsubunit

YLR089c similarity to alanine transaminasesYGL184c similarity to cystathionine β-lyaseYHR112c similarity to cystathionine γ-synthasesYIL074c similarity to E. coli phosphoglycerate

dehydrogenaseYGR012w similarity to E. nidulans cysteine synthaseYMR250w similarity to glutamate decarboxylasesYMR062c similarity to glutamate N-acetyltransferaseYDL131w similarity to homocitrate synthases and

isopropylmalate synthasesYIL094c similarity to isopropyl malate and tartrate

dehydrogenasesYEL038w UTR4 similarity to K. oxytoca enolase-

phosphatase E-1YML082w similarity to N. crassa

O-succinylhomoserine (thiol)-lyaseYJR130c similarity to O-succinylhomoserine

(thiol)-lyaseYKL215c similarity to P. aeruginosa hyuA and hyuBYOR280c similarity to S. pombe dihydrofolate

reductaseYFL030w similarity to several transaminasesYOR108w strong similarity to 2-isopropylmalate

synthaseYAL004w strong similarity to A. klebsiana glutamate

dehydrogenaseYDR111c strong similarity to alanine transaminaseYFR055w strong similarity to β-cystathionasesYHR033w strong similarity to glutamate 5-kinaseYHR070w strong similarity to N. crassa met-10+

proteinYLL058w strong similarity to N. crassa

O-succinylhomoserine (thiol)-lyaseYER081w strong similarity to phosphoglycerate

dehydrogenasesYJR010w MET3 sulphate adenylyltransferaseYCR053w THR4 threonine synthase (o-p-homoserine

p-lyase)YPR074c TKL1 transketolase 1YBR117c TKL2 transketolase 2YGL026c TRP5 tryptophan synthaseYML096w weak similarity to asparagine synthases

rreegguullaattiioonn ooff aammiinnoo--aacciidd mmeettaabboolliissmmYDR173c ARG82 arginine metabolism transcription factorYKL112w ABF1 ARS-binding factorYER055c HIS1 ATP phosphoribosyltransferaseYBR253w SRB6 DNA-directed RNA polymerase II

suppressor proteinYNL236w SIN4 global regulator protein

Metabolism 35amino-acid metabolismnitrogen and sulphur metabolismnucleotide metabolismphosphate metabolismcarbohydrate metabolismlipid, fatty-acid and sterol metabolismbiosynthesis of vitamins, cofactors and

prosthetic groupsionic homeostasis

Energy 40glycolysisgluconeogenesispentose-phosphate pathwaytricarboxylic-acid pathwayrespirationfermentationmetabolism of energy reserves (glycogen

and trehalose)other energy-generation activities

Cell growth, cell division and DNAsynthesis 41

cell growthbudding, cell polarity and filament formationpheromone response and mating-type

determinationsporulation and germinationmeiosisDNA synthesis and replicationrecombination and DNA repaircell-cycle control and mitosiscytokinesisother cell-growth, cell-division and DNA-

synthesis activities

Transcription 45rRNA synthesis rRNA processingother rRNA-transcription activitiestRNA synthesistRNA processing

tRNA modificationother tRNA-transcription activitiesmRNA synthesismRNA processing (splicing)mRNA processing (5’-end, 3’-end processing

and mRNA degradation)other mRNA-transcription activitiesRNA transportother transcription activities

Protein synthesis 48ribosomal proteinstranslation (initiation,elongation and

termination)translational controltRNA synthetasesother protein-synthesis activities

Protein destination 49protein folding and stabilizationprotein targeting, sorting and translocationprotein modification (glycosylation, acylation,

myristylation, palmitylation, farnesylationand processing)

assembly of protein complexesproteolysisother protein-destination activities

Transport facilitation 51ion channelsion transporterssugar and carbohydrate transportersamino-acid transporterslipid transporterspurine and pyrimidine transportersallantoin and allantoate transporterstransport ATPasesABC transportersdrug transportersother transport-facilitators

Intracellular transport 53nuclear transport

mitochondrial transportvesicular transport (Golgi network, etc.)peroxisomal transportvacuolar transportextracellular transportcellular importother intracellular-transport activities

Cellular organization and biogenesis 54organization and biogenesis of cell wall and

plasma membraneorganization and biogenesis of

cytoskeletonorganization and biogenesis of endoplasmic

reticulum and Golgiorganization and biogenesis of chromosome

structuremitochondrial organization and biogenesisperoxisomal organization and biogenesisendosomal organization and biogenesisvacuolar and lysosomal organization and

biogenesisother cellular organization and biogenesis

activities

Signal transduction 58pheromone response generationmorphogenesisosmosensing nutritional response other signal-transduction activities

Cell rescue 59stress response generationDNA repair (direct repair, base excision

repair and nucleotide excision repair)detoxificatoncell death and ageingdegradation of exogenous polynucleotidesother cell-rescue activities

Unclassified proteins 60

YFL010w-a AUA1 involved in ammonia regulation of amino-acid transport

YIL046w MET30 involved in regulation of sulphurassimilation genes

YJR060w CBF1 kinetochore proteinYDR159w SAC3 leucine permease transcriptional regulatorYDR207c UME6 negative transcriptional regulatorYKL015w PUT3 positive activator of the proline utilisation

pathwayYCR028c FEN2 similarity to allantoate permease

transporterYMR116c strong similarity to N. crassa CPC2

proteinYKR099w BAS1 transcription factorYLR098c CHA4 transcription factorYLR451w LEU3 transcription factorYMR042w ARG80 transcription factor involved in arginine

metabolismYML099c ARG81 transcription factor involved in arginine

metabolismYMR043w MCM1 transcription factor of the MADS box

familyYIR023w DAL81 transcriptional activator for allantoin and

GABA catabolic genesYEL009c GCN4 transcriptional activator of amino acid

biosynthetic genesYDR034c LYS14 transcriptional activator of lysine pathway

genesYIR017c MET28 transcriptional activator of sulphur amino

acid metabolismYNL103w MET4 transcriptional activator of sulphur

metabolism

aammiinnoo--aacciidd ttrraannssppoorrttYBR068c BAP2 amino-acid permeaseYEL063c CAN1 amino-acid permeaseYBR069c VAP1 amino-acid permeaseYCL025c AGP1 asparagine and glutamine permeaseYPL265w DIP5 dicarboxylic amino-acid permeaseYKR039w GAP1 general amino-acid permeaseYDR508c GNP1 high-affinity glutamine permeaseYGR055w MUP1 high-affinity methionine permeaseYNL270c ALP1 high-affinity permease for basic amino

acidsYOL020w SCM2 high-affinity tryptophan transport proteinYGR191w HIP1 histidine permeaseYLR375w STP3 involved in pre-tRNA splicing and in

uptake of branched-chain amino acidsYDL048c STP4 involved in pre-tRNA splicing and in

uptake of branched-chain amino acidsYNL268w LYP1 lysine-specific high affinity permeaseYOR130c ARG11 member of the mitochondrial carrier

family (MCF)YHL036w MUP3 methionine permeaseYOR348c PUT4 proline and γ-aminobutyrate permeaseYFL055w similarity to Gap1p and other amino-acid

permeasesYDR160w similarity to lysine transport protein LYP1YLL061w strong similarity to amino-acid transport

protein Gap1pYPL274w strong similarity to amino-acid transport

proteinsYDR046c (PAP1) strong similarity to amino-acid transport

proteinsYBR132c strong similarity to amino-acid permeases

aammiinnoo--aacciidd ddeeggrraaddaattiioonn YPL111w CAR1 arginaseYDR321w ASP1 asparaginaseYOR375c GDH1 glutamate dehydrogenase (NADP+)YMR189w GSD2 glycine decarboxylase subunitYDR019c GCV1 glycine decarboxylase T subunitYDR272w GLO2 glyoxalase IIYOR040w GLO4 glyoxalase IIYLR155c ASP3A L-asparaginase IIYLR157c ASP3B L-asparaginase IIYLR158c ASP3C L-asparaginase IIYLR160c ASP3D L-asparaginase IIYCL064c CHA1 L-serine/L-threonine deaminaseYAL062w GDH3 NADP-glutamate dehydrogenaseYDL215c GDH2 NAD-specific glutamate dehydrogenase

(NAD)YKL184w ORD1 ornithine decarboxylaseYLR142w PUT1 proline oxidaseYLR180w SAM1 S-adenosylmethionine synthetase 1YDR502c SAM2 S-adenosylmethionine synthetase 2YIL167w SDL1 serine dehydrataseYDR294c similarity to glutamate decarboxylasesYJR078w similarity to indoleamine 2,3-dioxygenaseYIL042c similarity to rat branched-chain α-ketoacid

dehydrogenase kinaseYGL202w similarity to rat kynurenine/

α-aminoadipate aminotransferaseYHR137w similarity to rat kynurenine/

α-aminoadipate aminotransferaseYFL030w similarity to several transaminasesYDR111c strong similarity to alanine transaminaseYBR006w strong similarity to E. coli succinate

semialdehyde dehydrogenaseYAL044c GCV3 strong similarity to human glycine

cleavage system protein HYIL168w SDL1 strong similarity to L-serine dehydratase

Cha1pYLR231c strong similarity to rat kynureninaseYKL218c strong similarity to threonine dehydrataseYBR208c DUR1,2 urea amidolyase

ootthheerr aammiinnoo--aacciidd mmeettaabboolliissmm aaccttiivviittiieessYKL157w APE2 aminopeptidase yscIIYGL017w ATE1 arginyl tRNA transferaseYPR069c SPE3 putrescine aminopropyltransferase

(spermidine synthase)YFR018c similarity to human glutaminyl-peptide

cyclotransferase

nitrogen and sulphur metabolism

nniittrrooggeenn aanndd ssuullpphhuurr uuttiilliizzaattiioonnYPR167c MET16 3’-phosphoadenylylsulphate reductaseYIR027c DAL1 allantoinaseYIR029w DAL2 allantoinaseYDR242w AMD2 amidaseYOL058w ARG1 argininosuccinate synthetaseYLR027c AAT2 aspartate aminotransferase, cytosolicYFR030w MET10 assimilatory sulphite reductase flavin-

binding subunitYKL001c MET14 ATP adenosine-5’-phosphosulphate

3’-phosphotransferaseYHR176w FMO flavin-containing monooxygenaseYOR375c GDH1 glutamate dehydrogenase (NADP+)YDL171c GLT1 glutamate synthase (NAPDPH) (GOGAT)YPR035w GLN1 glutamate-ammonia ligaseYJL172w CPS1 Gly-X carboxypeptidase YSCS YAL062w GDH3 NADP-glutamate dehydrogenaseYDL215c GDH2 NAD-specific glutamate dehydrogenase

(NAD)YLR438w CAR2 ornithine aminotransferaseYJR149w similarity to 2-nitropropane dioxygenaseYLR089c similarity to alanine transaminasesYMR293c similarity to amidasesYFL061w similarity to M. verrucaria cyanamide

hydrataseYFL030w similarity to several transaminasesYOR251c similarity to thiosulphate

sulphurtransferasesYDR111c strong similarity to alanine transaminaseYER057c strong similarity to Azotobacter nitrogen

fixation vnfA proteinYIL051c strong similarity to Azotobacter nitrogen

fixation vnfA proteinYJL060w strong similarity to kynurenine

aminotransferaseYPL135w strong similarity to nitrogen fixation

protein (nifU)YOR226c strong similarity to nitrogen fixation

proteinsYJR010w MET3 sulphate adenylyltransferaseYJR137c sulphite reductaseYBR208c DUR1,2 urea amidolyaseYIR032c DAL3 ureidoglycolate hydrolaseYJL035c weak similarity to B. japonicum nitrogen

fixation proteinYKL040c weak similarity to nitrogen fixation protein

nifU

rreegguullaattiioonn ooff nniittrrooggeenn aanndd ssuullpphhuurr uuttiilliizzaattiioonnYGR019w UGA1 4-aminobutyrate aminotransferase (GABA

transaminase)YPL111w CAR1 arginaseYKL112w ABF1 ARS-binding factorYNL216w RAP1 DNA-binding protein with repressor and

activator activityYFL010w-a AUA1 involved in ammonia regulation of amino

acid transportYIR030c DCG1 involved in nitrogen-catabolite metabolismYBR213w MET8 involved in the expression of PAPS

reductase and sulphite reductaseYDR207c UME6 negative transcriptional regulatorYNL229c URE2 nitrogen catabolite repression regulatorYEL062w NPR2 nitrogen permease regulatorYNL183c NPR1 ser/thr protein kinaseYCR028c FEN2 similarity to allantoate permease

transporterYLR013w similarity to nitrogen regulatory proteinsYGL254w FZF1 sulphite resistance proteinYFL021w GAT1 transcription factor for nitrogen regulationYER040w GLN3 transcription factor for positive nitrogen

regulationYMR042w ARG80 transcription factor involved in arginine


metabolismYMR043w MCM1 transcription factor of the MADS box

familyYIR023w DAL81 transcriptional activator for allantoin and

GABA catabolic genesYDL170w UGA3 transcriptional activator for GABA

catabolic genesYNL103w MET4 transcriptional activator of sulphur

metabolismYKR034w DAL80 transcriptional repressor for allantoin and

GABA catabolic genes

nniittrrooggeenn aanndd ssuullpphhuurr ttrraannssppoorrttYGR121c MEP1 ammonia permease of high capacity and

moderate affinityYNL142w MEP2 high-affinity low-capacity ammonia

permeaseYBR294w SUL1 high-affinity sulphate transport proteinYPR003c similarity to sulphate transporter proteinsYPR138c MEP3 strong similarity to ammonium transport

proteinsYLR092w SEL2 strong similarity to Sul1pYHL016c DUR3 urea transport protein

nucleotide metabolism

ppuurriinnee--rriibboonnuucclleeoottiiddee mmeettaabboolliissmmYLR028c ADE16 5-aminoimidazole-4-carboxamide ribotide

transformylaseYGR061c ADE6 5’-phosphoribosylformyl glycinamidine

synthetaseYML022w APT1 adenine phosphoribosyltransferaseYDR441c APT2 adenine phosphoribosyltransferaseYNL220w ADE12 adenylosuccinate synthetaseYIR027c DAL1 allantoinaseYIR029w DAL2 allantoinaseYMR300c ADE4 amidophosphoribosyltransferaseYML035c AMD1 AMP deaminaseYGR204w ADE3 C1-tetrahydrofolate synthase, cytoplasmicYBR084w MIS1 C1-tetrahydrofolate synthase,

mitochondrialYOR236w DFR1 dihydrofolate reductaseYMR217w GUA1 GMP synthase (glutamine-hydrolyzing)YHR216w PUR5 IMP dehydrogenaseYIR031c DAL7 malate synthase 2YKR080w MTD1 methylenetetrahydrofolate dehydrogenase

(NAD+)YAR015w ADE1 phosphoribosylamidoimidazole-

succinocarboxamide synthaseYGL234w ADE5,7 phosphoribosylamine-glycine ligase and

phosphoribosylformylglycinamidine cyclo-ligase

YOR128c ADE2 phosphoribosylaminoimidazolecarboxylase

YDR408c ADE8 phosphoribosylglycinamideformyltransferase (GART)

YKL181w PRPS1 ribose-phosphate pyrophosphokinaseYER099c PRS2 ribose-phosphate pyrophosphokinaseYHL011c PRS3 ribose-phosphate pyrophosphokinaseYBL068w PRS4 ribose-phosphate pyrophosphokinaseYLR058c SHM2 serine hydroxymethyltransferase,

cytoplasmicYBR263w SHM1 serine hydroxymethyltransferase,

mitochondrialYNL141w similarity to adenosine deaminaseYBR284w similarity to AMP deaminaseYJL070c similarity to AMP deaminasesYLR017w similarity to human 5’-

methylthioadenosine phosphorylaseYOL061w similarity to ribose-phosphate

pyrophosphokinasesYOR280c similarity to S. pombe dihydrofolate

reductaseYDR020c similarity to uridine kinases and

phosphoribulokinasesYLR359w strong similarity to adenylosuccinate

lyaseYMR120c strong similarity to chicken purH

bifunctional enzymeYJR105w strong similarity to human adenosine

kinaseYAR075w strong similarity to IMP dehydrogenasesYML056c strong similarity to IMP dehydrogenasesYAR073w FUN63 strong similarity to IMP dehydrogenasesYLR432w strong similarity to IMP dehydrogenases,

Pur5p and YML056cYLR209c strong similarity to purine-nucleoside

phosphorylasesYBR208c DUR1,2 urea amidolyaseYIR032c DAL3 ureidoglycolate hydrolase

ppyyrriimmiiddiinnee--rriibboonnuucclleeoottiiddee mmeettaabboolliissmmYBL039c URA7 CTP synthase 1YJR103w URA8 CTP synthase 2YHR144c DCD1 deoxycytidylate deaminaseYLR420w URA4 dihydroorotaseYKL216w URA1 dihydroorotate dehydrogenaseYJR057w CDC8 dTMP kinaseYBR252w DUT1 dUTP pyrophosphatase, mitochondrialYJL130c URA2 multifunctional pyrimidine biosynthesis

proteinYML106w URA5 orotate phosphoribosyltransferase 1YMR271c URA10 orotate phosphoribosyltransferase 2YEL021w URA3 orotidine-5’-phosphate decarboxylaseYFL058w THI5 pyrimidine biosynthesis proteinYKL181w PRPS1 ribose-phosphate pyrophosphokinaseYER099c PRS2 ribose-phosphate pyrophosphokinaseYHL011c PRS3 ribose-phosphate pyrophosphokinaseYBL068w PRS4 ribose-phosphate pyrophosphokinaseYOL061w similarity to ribose-phosphate

pyrophosphokinasesYOR280c similarity to S. pombe dihydrofolate

reductaseYLR245c strong similarity to B. subtilis cytidine

deaminaseYNL332w strong similarity to Thi5p, YJR156c,

YDL244w and A. parasiticus, S. pombeNmt1p

YDL244w strong similarity to Thi5p, YJR156c,YNL332w and A. parasiticus, S. pombenmt1 protein

YJR156c THI11 thiamine regulated gene, homologous tonmt1a in S. pombe

YHR128w FUR1 uracil phosphoribosyltransferaseYNR012w URK1 uridine kinaseYKL024c URA6 uridine-monophosphate kinase

ddeeooxxyyrriibboonnuucclleeoottiiddee mmeettaabboolliissmmYDR513w TTR1 glutaredoxinYER070w RNR1 ribonucleoside-diphosphate reductase,

large subunit

36 NATURE | VOL 387 | SUPP | 29 MAY 1997

gazetteer

YJL026w RNR2 ribonucleoside-diphosphate reductase,small subunit

YGR180c RNR4 ribonucleotide reductase small subunitYIL066c RNR3 ribonucleotide reductase, repair inducible

large subunitYBR014c similarity to glutaredoxinYPL059w similarity to glutaredoxinsYOR269w PAC1 similarity to human LIS-1 proteinYDL010w similarity to hypothetical protein YBR014c

and glutaredoxinsYCL035c strong similarity to glutaredoxinYDR353w strong similarity to thioredoxin reductase

(NADPH)YHR106w strong similarity to thioredoxin reductasesYOR074c CDC21 thymidylate synthase

mmeettaabboolliissmm ooff ccyycclliicc aanndd uunnuussuuaall nnuucclleeoottiiddeessYJL005w CYR1 adenylate cyclaseYCL050c APA1 ATP adenylyltransferase IYDR530c APA2 ATP adenylyltransferase IIYOL081w IRA2 GTPase-activating protein for RAS

proteinsYOR360c PDE2 high affinity 3’,5’-cyclic-nucleotide

phosphodiesteraseYPL212c PUS1 pseudouridine synthase 1YGL063w PUS2 pseudouridine synthase 2

rreegguullaattiioonn ooff nnuucclleeoottiiddee mmeettaabboolliissmmYOL081w IRA2 GTPase-activating protein for RAS

proteinsYOR101w RAS1 GTP-binding proteinYNL098c RAS2 GTP-binding proteinYDL106c GRF10 homeodomain proteinYGL248w PDE1 low-affinity 3’,5’-cyclic-nucleotide

phosphodiesteraseYNL076w MKS1 negative regulator of RAS-cAMP pathwayYJL096w putative regulator of purine and/or

pyrimidine biosynthesisYOL110w SHR5 RAS suppressorYKR099w BAS1 transcription factorYLR014c PPR1 transcription factor regulating pyrimidine

pathwayYIR023w DAL81 transcriptional activator for allantoin and

GABA catabolic genesYNL314w DAL82 transcriptional activator for allantoin

catabolic genes

ppoollyynnuucclleeoottiiddee ddeeggrraaddaattiioonnYMR287c MSU1 3’-5’ exonuclease for RNA 3’ ss-tail,

mitochondrialYPL029w SUV3 ATP-dependent RNA helicase,

mitochondrialYOR033c DHS1 exonuclease, interacting with Msh2pYKL149c DBR1 lariat-debranching enzymeYGL173c KEM1 multifunctional nucleaseYLR363c NMD4 Nam7p/Upf1p-interacting proteinYJR132w NMD5 Nam7p/Upf1p-interacting proteinYMR080c NAM7 nonsense-mediated mRNA decay proteinYGR072w UPF3 nonsense-mediated mRNA decay proteinYHR077c NMD2 nonsense-mediated mRNA decay protein

2YJL208c NUC1 nuclease, mitochondrialYMR234w RNH1 ribonuclease HYPL123c similarity to ribonucleasesYGR195w weak similarity to P. aeruginosa RNase

PH

nnuucclleeoottiiddee ttrraannssppoorrttYMR056c AAC1 ADP/ATP carrier protein (MCF)YBL030c AAC2 ADP/ATP carrier protein (MCF)YBR085w AAC3 ADP/ATP carrier protein (MCF)YER056c FCY2 purine-cytosine permeaseYER060w FCY21 purine-cytosine permeaseYOR222w similarity to ADP/ATP carrier proteinsYPR011c similarity to ADP/ATP carrier proteins and

Graves disease carrier proteinYOR071c similarity to allantoin or uracil transport

proteinsYOR192c similarity to allantoin or uracil transport

proteinsYLR237w similarity to allantoin transport proteinYGR096w similarity to bovine Graves disease carrier

proteinYHR002w similarity to bovine mitochondrial carrier

protein/Grave’s disease carrier proteinYGL186c similarity to hypothetical protein YER060w

and weak similarity to Fcy2pYBL042c strong similarity to allantoin and uracil

transport proteinsYER060w-a FCY22 strong similarity to Fcy2pYBR021w FUR4 uracil permease

ootthheerr nnuucclleeoottiiddee--mmeettaabboolliissmm aaccttiivviittiieessYDR226w ADK1 adenylate kinase, cytosolicYER170w ADK2 adenylate kinase, mitochondrialYDR454c GUK1 guanylate kinaseYKL067w YNK1 nucleoside diphosphate kinaseYDL125c HNT1 similarity to protein kinase C inhibitor-IYDR305c HNT2 strong similarity to S. pombe diadenosine

5’,5’’’-P1,P4-tetraphosphate asymmetricalhydrolase

phosphate metabolism

pphhoosspphhaattee uuttiilliizzaattiioonnYHR044c DOG1 2-deoxyglucose-6-phosphate

phosphatase

YHR043c DOG2 2-deoxyglucose-6-phosphatephosphatase

YMR282c AEP2 2’-O-ribosyl phosphate transferaseYBR092c PHO3 constitutive acid phosphatase YHR201c PPX1 exopolyphosphataseYBR011c IPP1 inorganic pyrophosphatase, cytoplasmicYMR267w PPA2 inorganic pyrophosphatase, mitochondrialYBR093c PHO5 repressible acid phosphatase YAR071w PHO11 secreted acid phosphataseYHR215w PHO12 secreted acid phosphataseYDL024c strong similarity to acid phosphataseYNL330c RPD3 transcription modifier proteinYBR243c ALG7 UDP-N-acetylglucosamine-1-phosphate

transferase

rreegguullaattiioonn ooff pphhoosspphhaattee uuttiilliizzaattiioonnYOL001w PHO80 cyclinYGR233c PHO81 cyclin-dependent kinase inhibitorYPL031c PHO85 cyclin-dependent protein kinaseYML121w GTR1 GTP-binding proteinYDL106c GRF10 homeodomain proteinYBR106w PHO88 involved in phosphate transportYFR034c PHO4 transcription factor

pphhoosspphhaattee ttrraannssppoorrttYLR348c dicarboxylate carrier proteinYML123c PHO84 high-affinity inorganic phosphate/H+

symporterYJL117w PHO86 inorganic phospate transporterYBR106w PHO88 involved in phosphate transportYCR037c PHO87 member of the phosphate permease

familyYJR077c MIR1 phosphate transport protein,

mitochondrial (MCF)YNR013c similarity to membrane protein Pho87p

and hypothetical protein YJL198wYCR098c GIT1 similarity to phosphate transporter

proteinsYER053c strong similarity to mitochondrial

phosphate carrier proteinYJL198w strong similarity to Pho87pYBR296c strong similarity to phosphate-repressible

phosphate permease

ootthheerr pphhoosspphhaattee--mmeettaabboolliissmm aaccttiivviittiieessYDL236w PHO13 4-nitrophenylphosphataseYOR008c SLG1 weak similarity to L. mexicana lmsap2

gene

carbohydrate metabolism

ccaarrbboohhyyddrraattee uuttiilliizzaattiioonnYLR342w FKS1 1,3-—D-glucan synthase, catalytic subunit YGR032w GSC2 1,3-—D-glucan synthase, subunitYEL011w GLC3 1,4-glucan branching enzyme (glycogen

branching enzyme)YHR044c DOG1 2-deoxyglucose-6-phosphate

phosphataseYHR043c DOG2 2-deoxyglucose-6-phosphate

phosphataseYIL125w KGD1 2-oxoglutarate dehydrogenase complex

E1 componentYDR148c KGD2 2-oxoglutarate dehydrogenase complex

E2 componentYGR240c PFK1 6-phosphofructokinase, α subunitYMR205c PFK2 6-phosphofructokinase, β subunitYIL107c PFK26 6-phosphofructose-2-kinase, isoenzyme 1YOL136c PFK27 6-phosphofructose-2-kinase, isoenzyme 2YHR183w GND1 6-phosphogluconate dehydrogenaseYBR001c NTH2 α,α-trehalaseYDR074w TPS2 α,α-trehalose-phosphate synthase, 105K

subunitYMR261c TPS3 α,α-trehalose-phosphate synthase, 115K

subunitYML100w TSL1 α,α-trehalose-phosphate synthase, 123K

subunitYBR126c TPS1 α,α-trehalose-phosphate synthase, 56K

subunitYJR131w MNS1 α-1,2-mannosidaseYDR483w KRE2 α-1,2-mannosyltransferaseYER001w MNN1 α-1,3-mannosyltransferaseYGL038c OCH1 α-1,6-mannosyltransferaseYAL054c ACS1 acetyl-CoA synthetaseYLR153c ACS2 acetyl-CoA synthetaseYPR026w ATH1 acid trehalase, vacuolarYBR299w MAL32 α-glucosidaseYGR292w MAL12 α-glucosidase of the MAL1 locusYOR377w ATF1 alcohol acetyltransferaseYOL086c ADH1 alcohol dehydrogenase IYMR303c ADH2 alcohol dehydrogenase IIYMR083w ADH3 alcohol dehydrogenase IIIYGL256w ADH4 alcohol dehydrogenase IVYBR145w ADH5 alcohol dehydrogenase VYGR177c ATF2 alcohol O-acetyltransferaseYCL040w GLK1 aldohexose specific glucokinaseYGL156w AMS1 α-mannosidaseYGL027c CWH41 β-1,6-glucan assembly proteinYHR101c BIG1 big cells phenotypeYBR110w ALG1 β-mannosyltransferaseYBR084w MIS1 C1-tetrahydrofolate synthase,

mitochondrialYNL322c KRE1 cell-wall proteinYJL174w KRE9 cell-wall synthesis proteinYJL099w CHS6 chitin biosynthesis proteinYNL192w CHS1 chitin synthase IYBR038w CHS2 chitin synthase IIYBR023c CHS3 chitin synthase IIIYNR001c CIT1 citrate (si)-synthase, mitochondrial

YPR001w CIT3 citrate (si)-synthase, mitochondrialYCR005c CIT2 citrate (si)-synthase, peroxisomalYML086c ALO D-arabinino-1,4-lactone oxidaseYNL071w LAT1 dihydrolipoamide S-acetyltransferaseYDL174c DLD1 D-lactate ferricytochrome c

oxidoreductase (D-LCR)YER062c HOR2 DL-glycerol phosphataseYIL053w RHR2 DL-glycerol phosphataseYPL227c ALG5 dolichol-P-glucose synthetaseYPR183w DPM1 dolichyl-phosphate β-D-

mannosyltransferaseYJR143c PMT4 dolichyl-phosphate-mannose-protein

O-mannosyl transferaseYOR095c RKI1 D-ribose-5-phosphate ketol-isomeraseYJL121c POS18 D-ribulose-5-phosphate 3-epimeraseYGR282c BGL2 endo-1,3-—glucanase of the cell wallYLR286c CTS1 endochitinaseYGR254w ENO1 enolase I (2-phosphoglycerate

dehydratase)YHR174w ENO2 enolase II (2-phosphoglycerate

dehydratase)YOR393w ERR1 enolase-related proteinYPL281c ERR2 enolase-related proteinYOR190w SPR1 exo-1,3-—glucanase YDR261c EXG2 exo-1,3-—glucanase minor isoformYLR300w EXG1 exo-1,3-—glucanase(I/II), major isoformYIR019c STA1 extracellular α-1,4-glucan glucosidaseYLR377c FBP1 fructose-1,6-bisphosphataseYJL155c FBP26 fructose-2,6-bisphosphataseYKL060c FBA1 fructose-bisphosphate aldolase YDL049c KNH1 functional homologue of Kre9pYBR020w GAL1 galactokinaseYDR009w GAL3 galactokinaseYOR120w GCY1 galactose-induced protein of aldo/keto

reductase familyYPR159w KRE6 glucan synthase subunitYGR143w SKN1 glucan synthase subunitYKL104c GFA1 glucosamine-fructose-6-phosphate

transaminaseYNL241c ZWF1 glucose-6-phosphate dehydrogenaseYBR196c PGI1 glucose-6-phosphate isomeraseYBR229c ROT2 glucosidase II, catalytic subunitYOR002w ALG6 glucosyltransferaseYOR067c ALG8 glucosyltransferaseYJL052w TDH1 glyceraldehyde-3-phosphate

dehydrogenase 1YJR009c TDH2 glyceraldehyde-3-phosphate

dehydrogenase 2YGR192c TDH3 glyceraldehyde-3-phosphate

dehydrogenase 3YHL032c GUT1 glycerol kinaseYDL022w GPD1 glycerol-3-phosphate dehydrogenase

(NAD+), cytoplasmic YOL059w GPD3 glycerol-3-phosphate dehydrogenase

(NAD+), mitochondrialYIL155c GUT2 glycerol-3-phosphate dehydrogenase,

mitochondrialYPR160w GPH1 glycogen phosphorylaseYFL014w HSP12 heat-shock proteinYFR053c HXK1 hexokinase IYGL253w HXK2 hexokinase IIYDL013w HEX3 hexose metabolism-related proteinYDL182w LYS20 homocitrate synthaseYOR126c EST2 isoamyl acetate hydrolytic enzymeYNL037c IDH1 isocitrate dehydrogenase (NAD+) subunit

1, mitochondrialYOR136w IDH2 isocitrate dehydrogenase (NAD+) subunit

2, mitochondrialYDL066w IDP1 isocitrate dehydrogenase (NADP+),

mitochondrialYLR174w IDP2 isocitrate dehydrogenase, cytosolicYER065c ICL1 isocitrate lyaseYOR336w KRE5 killer toxin-resistance proteinYML054c CYB2 lactate dehydrogenase cytochrome b2YDL168w SFA1 long-chain alcohol dehydrogenaseYOL126c MDH2 malate dehydrogenase, cytoplasmicYKL085w MDH1 malate dehydrogenase, mitochondrialYDL078c MDH3 malate dehydrogenase, peroxisomalYNL117w MLS1 malate synthase 1YIR031c DAL7 malate synthase 2YDL055c PSA1 mannose-1-phosphate guanyltransferaseYER003c PMI40 mannose-6-phosphate isomeraseYGL065c ALG2 mannosyltransferaseYNL219c ALG9 mannosyltransferaseYKR061w KTR2 mannosyltransferaseYDL095w PMT1 mannosyltransferaseYAL023c PMT2 mannosyltransferaseYOR321w PMT3 mannosyltransferaseYBL082c RHK1 mannosyltransferaseYJL139c YUR1 mannosyltransferaseYJL153c INO1 myo-inositol-1-phosphate synthaseYPL175w SPT14 N-acetylglucosaminyltransferaseYDR001c NTH1 neutral trehalase (α,α-trehalase)YPR006c ICL2 non-functional isocitrate lyaseYJL002c OST1 oligosaccharyltransferase α subunitYEL002c WBP1 oligosaccharyltransferase β subunit YMR149w SWP1 oligosaccharyltransferase δ subunitYOR103c OST2 oligosaccharyltransferase ε subunitYOR085w OST3 oligosaccharyltransferase γ subunitYDL232w OST4 oligosaccharyltransferase subunitYGL022w STT3 oligosaccharyltransferase subunitYEL058w PCM1 phosphoacetylglucosamine mutaseYKR097w PCK1 phosphoenolpyruvate carboxykinaseYMR105c PGM2 phosphoglucomutase, major isoformYKL127w PGM1 phosphoglucomutase, minor isoformYGR256w GND2 phosphogluconate dehydrogenaseYCR012w PGK1 phosphoglycerate kinaseYKL152c GPM1 phosphoglycerate mutase


gazetteer

YOL056w GPM3 phosphoglycerate mutaseYFL045c SEC53 phosphomannomutaseYCR034w GNS1 probable 1,3-—glucan synthase subunitYIL045w PIG2 Protein interacting with Gsy2pYIL085c KTR7 putative α-1,2-mannosyltransferaseYNL029c KTR5 putative mannosyltransferaseYGR199w PMT6 putative mannosyltransferaseYGL062w PYC1 pyruvate carboxylase, isozyme 1YBR218c PYC2 pyruvate carboxylase, isozyme 2YDR081c PDC2 pyruvate decarboxylase regulatory proteinYLR044c PDC1 pyruvate decarboxylase, isozyme 1YLR134w PDC5 pyruvate decarboxylase, isozyme 2YGR087c PDC6 pyruvate decarboxylase, isozyme 3YER178w PDA1 pyruvate dehydrogenase (lipoamide)

α subunit YBR221c PDB1 pyruvate dehydrogenase (lipoamide)

β subunit YGR193c PDX1 pyruvate dehydrogenase complex protein

XYAL038w CDC19 pyruvate kinaseYNL048w ALG11 required for asparagine-linked

glycosylationYCR036w RBK1 ribokinaseYJL137c GLG2 self-glucosylating initiator of glycogen

synthesisYMR306w similarity to 1,3-—glucan synthasesYAL060w FUN49 similarity to alcohol/sorbitol

dehydrogenaseYAL061w FUN50 similarity to alcohol/sorbitol

dehydrogenaseYMR318c similarity to alcohol-dehydrogenaseYDL124w similarity to aldose reductasesYHR204w similarity to α-mannosidasesYPL088w similarity to aryl-alcohol dehydrogenasesYML070w similarity to C. feundii dihydroxyacetone

kinaseYIL124w similarity to C. perfringens nanH proteinYDR371w similarity to chitinasesYIR036c similarity to E. coli 3-ketoacyl-ACP

reductaseYBR149w similarity to Gcy1p and aldose reductasesYBR056w similarity to glucan 1,3-—glucosidaseYIL169c similarity to glucan 1,4-—glucosidaseYOL155c similarity to glucan 1,4-—glucosidase

Mal5pYNL274c similarity to glycerate- and formate-

dehydrogenasesYPL113c similarity to glycerate dehydrogenasesYPR184w similarity to glycogen debranching

enzymesYDL131w similarity to homocitrate synthases and

isopropylmalate synthasesYJR096w similarity to Leishmania reductaseYKR096w similarity to mitochondrial aldehyde

dehydrogenase Ald1pYGL257c similarity to Mnn1pYIL014w similarity to Mnn1pYEL020c similarity to O. formigenes oxalyl-CoA

decarboxylaseYDL093w PMT5 similarity to O-mannosyltransferases

Pmt1p-Pmt4pYMR278w similarity to phosphomannomutasesYDR307w similarity to Pmt1pYDR380w similarity to pyruvate decarboxylasesYDR245w MNN10 similarity to S. pombe

galactosyltransferaseYLR070c similarity to sugar dehydrogenasesYNR059w similarity to to α-1,3-mannosyltransferaseYHL012w similarity to UDP glucose

pyrophosphorylaseYJR159w SOR1 sorbitol dehydrogenaseYIL099w SGA1 sporulation specific glucan

1,4-—glucosidaseYER096w SHC1 sporulation-specific proteinYLR307w CDA1 sporulation-specific chitin deacetylaseYLR308w CDA2 sporulation-specific chitin deacetylaseYNL331c strong similarity to aryl-alcohol reductaseYCR107w strong similarity to aryl-alcohol reductasesYPL017c strong similarity to dihydrolipoamide

dehydrogenasesYBR205w KTR3 strong similarity to

α-1,2-mannosyltransferaseYBR199w KTR4 strong similarity to

α-1,2-mannosyltransferaseYPL053c KTR6 strong similarity to

α-1,2-mannosyltransferase Kre2pYJL221c FSP2 strong similarity to α-D-glucosidaseYOL157c strong similarity to α-glucosidasesYCR105w strong similarity to alcohol

dehydrogenasesYDL243c strong similarity to aryl-alcohol

dehydrogenaseYJR155w strong similarity to aryl-alcohol

dehydrogenaseYFL056c strong similarity to aryl-alcohol

dehydrogenasesYFL057c strong similarity to aryl-alcohol

dehydrogenasesYOL165c strong similarity to aryl-alcohol

dehydrogenasesYKR027w strong similarity to Chs6pYHR104w strong similarity to D-xylose

1-dehydrogenaseYEL070w strong similarity to E. coli D-mannonate

oxidoreductaseYNR073c strong similarity to E. coli D-mannonate

oxidoreductase, identical to YEL070w

YJL218w strong similarity to E. coli galactoside O-acetyltransferase

YDR248c strong similarity to E. coli thermoresistantgluconokinase

YIL172c strong similarity to Fsp2pYDL037c strong similarity to glucan

1,4-—glucosidaseYDR516c strong similarity to glucokinaseYOR299w strong similarity to hypothetical protein

YMR237w and similarity to Chs6pYMR237w strong similarity to hypothetical protein

YOR299w and similarity to CHS6 proteinYNL009w strong similarity to isocitrate

dehydrogenaseYJL216c strong similarity to Mal62pYGR287c strong similarity to maltaseYOR099w KTR1 strong similarity to mannosyltransferasesYDR368w YPR1 strong similarity to members of the

aldo/keto reductase familyYDL021w GPM2 strong similarity to phosphoglycerate

mutase Gpm1pYMR323w strong similarity to phosphopyruvate

hydratasesYJR153w strong similarity to polygalacturonasesYDL080c strong similarity to pyruvate

decarboxylasesYOR347c strong similarity to pyruvate kinaseYGR244c strong similarity to rumen fungus

β-succinyl-CoA synthetaseYKL029c strong similarity to S. pombe malate

oxireductaseYBL001c strong similarity to S. xylosus glucose

kinaseYLR164w strong similarity to Sdh4pYDL246c strong similarity to Sor1pYJL045w strong similarity to succinate

dehydrogenase flavoproteinYGR043c strong similarity to transaldolaseYNR071c strong similarity to UDP-glucose

4-epimerase Gal10pYDR384c strong similarity to Y. lipolytica GPR1

geneYHR210c strong similarity UDP-glucose-4-epimeraseYKL148c SDH1 succinate dehydrogenase flavoprotein YDR178w SDH4 succinate dehydrogenase membrane

anchor subunit for Sdh2pYIL162w SUC2 sucrose hydrolyzing enzymeYJR075w HOC1 suppressor of pkc1YLR354c TAL1 transaldolaseYPR074c TKL1 transketolase 1YBR117c TKL2 transketolase 2YDR050c TPI1 triose-phosphate isomeraseYBR019c GAL10 UDP-glucose 4-epimeraseYBR018c GAL7 UDP-glucose-hexose-1-phosphate

uridylyltransferaseYFR015c GSY1 UDP-glucose-starch glucosyltransferase,

isoform 1YLR258w GSY2 UDP-glucose-starch glucosyltransferase,

isoform 2YBR243c ALG7 UDP-N-acetylglucosamine-1-phosphate

transferaseYKL035w UGP1 UTP-glucose-1-phosphate

uridylyltransferaseYKR043c weak similarity to phosphoglycerate

mutaseYOR283w weak similarity to phosphoglycerate

mutases

rreegguullaattiioonn ooff ccaarrbboohhyyddrraattee uuttiilliizzaattiioonnYGR240c PFK1 6-phosphofructokinase, α subunitYMR205c PFK2 6-phosphofructokinase, β subunitYIL107c PFK26 6-phosphofructose-2-kinase, isoenzyme 1YOL136c PFK27 6-phosphofructose-2-kinase, isoenzyme 2YBR126c TPS1 α,α-trehalose-phosphate synthase, 56K

subunitYHR047c AAP1 alanine/arginine aminopeptidaseYGR229c KNR4 β-1,3-glucan synthesis proteinYOL067c RTG1 basic helix-loop-helix transcription factorYOR344c TYE7 basic helix-loop-helix transcription factorYGR166w KRE11 β-glucan synthesis-associated proteinYBL103c RTG3 bHLH/zip transcription factorYPL161c BEM4 bud emergence proteinYGL209w MIG2 C2H2 zinc-finger proteinYIL033c SRA1 cAMP dependent protein kinase,

regulatory subunitYDR477w SNF1 carbon catabolite derepressing ser/thr

protein kinaseYCR002c CDC10 cell division control proteinYLR330w CHS5 chitin synthesis proteinYDR073w SNF11 component of SWI/SNF transcription

activator complexYOR290c SNF2 component of SWI/SNF transcription

activator complexYBR289w SNF5 component of SWI/SNF transcription

activator complexYPL016w SWI1 component of SWI/SNF transcription

activator complexYPL042c SSN3 cyclin-dependent ser/thr protein kinaseYNL216w RAP1 DNA-binding protein with repressor and

activator activityYOL051w GAL11 DNA-directed RNA polymerase II

holoenzyme and Kornberg’s mediator(SRB) subcomplex subunit

YDR443c SCA1 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit

YCR081w SRB8 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit

YNL025c SSN8 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit, cyclin Chomologue

YLR071c RGR1 DNA-directed RNA polymerase IIholoenzyme subunit

YBR253w SRB6 DNA-directed RNA polymerase IIsuppressor protein

YOR047c STD1 dosage-dependent modulator of glucoserepression

YJL155c FBP26 fructose-2,6-bisphosphataseYPL037c EGD1 GAL4 DNA-binding enhancer proteinYDR009w GAL3 galactokinaseYLL016w SDC25 GDP/GTP exchange factorYLR310c CDC25 GDP/GTP exchange factor for Ras1p and

Ras2pYGR070w ROM1 GDP/GTP exchange protein for Rho1pYLR371w ROM2 GDP/GTP exchange protein for Rho1pYDR176w NGG1 general transcriptional adaptor or co-

activatorYER054c GIP2 Glc7p-interacting proteinYNL236w SIN4 global regulator proteinYHL025w SNF6 global transcription activatorYER027c GAL83 glucose repression proteinYNL199c GCR2 glycolytic genes transcriptional activatorYOR101w RAS1 GTP-binding proteinYNL098c RAS2 GTP-binding proteinYPR165w RHO1 GTP-binding protein of the RHO subfamily

of RAS-like proteinsYNL090w RHO2 GTP-binding protein of the RHO subfamily

of RAS-like proteinsYDR420w HKR1 Hansenula MrakII k9 killer toxin-resistance

proteinYGL253w HXK2 hexokinase IIYPL002c SNF8 involved in glucose derepressionYOR125c CAT5 involved in glucose repressionYML048w EFF2 involved in glucose repressionYNL201c involved in regulation of carbon

metabolismYGR227w DIE2 ITR1 expression promoting proteinYBR297w MAL33 maltose fermentation regulatory proteinYGR288w MAL13 maltose pathway regulatory proteinYLR131c ACE2 metallothionein expression activatorYDR422c SIP1 multicopy suppressor of snf1YML051w GAL80 negative regulator for expression of

galactose-induced genesYNL076w MKS1 negative regulator of RAS-cAMP pathwayYIL119c RPI1 negative regulator of RAS-cAMP pathwayYLR025w SNF7 nuclear proteinYGL115w SNF4 nuclear regulatory proteinYLR273c PIG1 protein interacting with Gsy2pYIL045w PIG2 protein Interacting with Gsy2pYDL006w PTC1 protein ser/thr phosphatase 2cYDL134c PPH21 protein ser/thr phosphatase PP2A-1YDL188c PPH22 protein ser/thr phosphatase PP2A-2YBL061c SKT5 protoplast regeneration and killer toxin

resistance proteinYOL110w SHR5 RAS suppressorYJR095w ACR1 regulator of acetyl-CoA synthetase activityYKL038w RGT1 regulator of glucose induced genesYDR028c REG1 regulatory subunit for protein

phosphatase Glc7pYMR311c GLC8 regulatory subunit for protein ser/thr

phosphatase Glc7pYBR050c REG2 regulatory subunit of type I protein

phosphataseYDR277c MTH1 repressor of hexose transport genesYNR052c POP2 required for glucose derepressionYJR090c GRR1 required for glucose repression and for

glucose and cation transportYGL252c RTG2 retrograde regulation proteinYJR076c CDC11 septinYHR107c CDC12 septinYER133w GLC7 ser/thr phosphoprotein phosphatase 1,

catalytic subunitYOR178c GAC1 ser/thr phosphoprotein phosphatase 1,

regulatory subunit YLR113w HOG1 ser/thr protein kinase of MAP kinase

(MAPK) familyYLR345w similarity to 6-phosphofructo-2-kinaseYCR028c FEN2 similarity to allantoate permease

transporterYFL053w similarity to C. freundii dihydroxyacetone

kinaseYDL225w similarity to Cdc11p, Cdc3p and human

CDC10 proteinYHR193c EGD2 similarity to human α-NACYDL203c similarity to Skt5pYNL257c SIP3 Snf1p protein kinase interacting proteinYLR150w MPT4 specific affinity for guanine-rich

quadruplex nucleic acidsYFL052w strong similarity to Mal63p, Mal23p and

Mal33pYHR155w strong similarity to Snf1p-interacting

protein Sip3pYNR002c FUN34 strong similarity to Y. lipolytica glyoxylate

pathway regulator GPR1YCR010c strong similarity to Y. lipolytica GPR1

protein and Fun34pYIL154c (IMP2) sugar utilization regulatory proteinYPL026c SKS1 suppressor kinase of snf3YPL129w ANC1 TFIIF subunit (transcription initiation

factor), 30KYPL248c GAL4 transcription factorYMR125w GCR3 transcription factor for glycolytic genes


gazetteer

YMR280c CAT8 transcription factor involved ingluconeogenesis

YMR043w MCM1 transcription factor of the MADS boxfamily

YJL176c SWI3 transcription regulatory proteinYPL075w GCR1 transcriptional activatorYOL116w MSN1 transcriptional activatorYKL062w MSN4 transcriptional activatorYGL035c MIG1 transcriptional repressorYIL147c SLN1 two-component signal transducerYLR006c SSK1 two-component signal transducerYJL128c PBS2 tyrosine protein kinase of the MAP kinase

kinase familyYLR258w GSY2 UDP-glucose-starch glucosyltransferase,

isoform 2YDR216w ADR1 zinc-finger transcription factor

ccaarrbboohhyyddrraattee ttrraannssppoorrttYCL040w GLK1 aldohexose specific glucokinaseYKL217w JEN1 carboxylic acid transporter proteinYBR291c CTP1 citrate transport protein, mitochondrial

(MCF)YLR348c dicarboxylate carrier proteinYLR081w GAL2 galactose (and glucose) permeaseYGR289c AGT1 general α-glucoside permeaseYLL043w FPS1 glycerol channel proteinYNL318c HXT14 hexose transport proteinYJL214w HXT8 hexose transport proteinYJL219w HXT9 hexose transport proteinYFL011w HXT10 hexose transporterYDL194w SNF3 high-affinity glucose transporterYEL069c HXT13 high-affinity hexose transporterYMR011w HXT2 high-affinity hexose transporterYDR343c HXT6 high-affinity hexose transporterYDR342c HXT7 high-affinity hexose transporterYOL156w HXT11 low-affinity glucose transporterYHR094c HXT1 low-affinity hexose transporterYDR345c HXT3 low-affinity hexose transporterYDR497c ITR1 major myo-inositol permeaseYBR298c MAL31 maltose permeaseYHR092c HXT4 moderate- to low-affinity glucose

transporterYOL103w ITR2 myo-inositol transport proteinYIR035c similarity to C. lanceolata 3-oxoacyl-[acyl-

carrier-protein] reductaseYBR241c similarity to glucose transport proteinsYGL104c similarity to glucose transport proteinsYPR021c similarity to human citrate transporter

proteinYDR387c similarity to Itr1p and Itr2pYDL199c similarity to sugar transporter proteinsYFL040w similarity to yeast glucose transport

proteinsYHR096c HXT5 strong similarity to hexose transportersYDL245c HXT15 strong similarity to Hxt17p and Haxt7pYJR160c strong similarity to Mal3TpYDR536w STL1 strong similarity to members of the sugar

permease familyYDL247w strong similarity to sugar transport

proteinsYIL170w HXT12 strong similarity to sugar transport


proteinsYJR158w HXT16 strong similarity to sugar transport

proteinsYNR072w HXT17 sugar transport proteinYDL138w RGT2 suppressor of snf3 mutant

lipid, fatty-acid and sterol metabolism

lliippiidd,, ffaattttyy--aacciidd aanndd sstteerrooll bbiioossyynntthheessiissYML075c HMG1 3-hydroxy-3-methylglutaryl-CoA

reductase 1YLR450w HMG2 3-hydroxy-3-methylglutaryl-CoA

reductase 2YML126c HMGS 3-hydroxy-3-methylglutaryl-CoA synthaseYPL028w ERG10 acetyl-CoA C-acetyltransferase, cytosolicYNR016c ACC1 acetyl-CoA carboxylaseYCR048w ARE1 acyl-CoA sterol acyltransferaseYNR019w ARE2 acyl-CoA sterol acyltransferaseYIL009w FAA3 acyl-CoA synthaseYGR037c ACB1 acyl-CoA-binding protein (diazepam-

binding inhibitor)YBR222c PCS60 AMP-binding protein, peroxisomalYER061c CEM1 β-keto-acyl-ACP synthaseYNL280c ERG24 C-14 sterol reductaseYMR015c ERG5 C-22 sterol desaturaseYGR060w ERG25 C-4 sterol methyl oxidaseYLR056w ERG3 C-5 sterol desaturaseYMR202w ERG2 C-8 sterol isomeraseYML042w CAT2 carnitine O-acetyltransferaseYPR113w PIS1 CDP diacylglycerol-inositol

3-phosphatidyltransferaseYER026c CHO1 CDP-diacylglycerol serine

O-phosphatidyltransferaseYBR029c CDS1 CDP-diacylglycerol synthaseYLR133w CKI1 choline kinaseYGR007w MUQ1 choline phosphate cytidylyltransferaseYGR202c PCT1 cholinephosphate cytidylyltransferaseYNL111c CYB5 cytochrome b5YHR007c ERG11 cytochrome P450 lanosterol

14a-demethylaseYHR190w ERG9 farnesyl-diphosphate farnesyltransferaseYJL167w ERG20 farnesyl-pyrophosphate synthetaseYDL052c SLC1 fatty acyltransferaseYPL231w FAS2 fatty-acyl-CoA synthase, α subunitYKL182w FAS1 fatty-acyl-CoA synthase, β subunit

YPL069c BTS1 geranylgeranyl diphosphate synthaseYGL126w SCS3 inositol phospholipid synthesis proteinYOR237w HES1 involved in ergosterol biosynthesisYPL145c KES1 involved in ergosterol biosynthesisYPL117c IDI1 isopentenyl-diphosphate δ-isomeraseYHR072w ERG7 lanosterol synthaseYMR246w FAA4 long-chain-fatty-acid-CoA ligaseYNL219c ALG9 mannosyltransferaseYJR073c OPI3 methylene-fatty-acyl-phospholipid

synthaseYNR043w MVD1 mevalonate pyrophosphate

decarboxylaseYPL076w GPI2 N-acetylglucosaminyl-phosphatidylinositol

biosynthetic proteinYPL175w SPT14 N-acetylglucosaminyltransferaseYGR157w CHO2 phosphatidylethanolamine

N-methyltransferaseYDL142c PGS1 phosphatidylglycerophosphate synthaseYNL169c PSD1 phosphatidylserine decarboxylase 1YGR170w PSD2 phosphatidylserine decarboxylase 2YCL004w PEL1 phosphatidylserine synthaseYMR220w ERG8 phosphomevalonate kinaseYCR034w GNS1 probable 1,3-—glucan synthase subunitYGL001c putative 3-—hydroxysteroid dehydrogenaseYJL196c ELO1 required for elongation of fatty acidsYGR216c GPI1 required for N-acetylglucosaminyl

phosphatidylinositol synthesisYML008c ERG6 S-adenosyl-methionine δ-24-sterol-c-

methyltransferaseYMR296c LCB1 serine C-palmitoyltransferase subunitYDR062w LCB2 serine C-palmitoyltransferase subunitYLR058c SHM2 serine hydroxymethyltransferase,

cytoplasmicYBR263w SHM1 serine hydroxymethyltransferase,

mitochondrialYMR207c HFA1 similarity to acetyl-CoA carboxylaseYDR147w similarity to choline kinaseYBR159w similarity to human 17-—hydroxysteroid

dehydrogenaseYDR376w ARH1 similarity to human adrenodoxin

reductaseYML131w similarity to human leukotriene b4

12-hydroxydehydrogenaseYAR042w OSH1 similarity to human oxysterol binding

proteinYDR208w MSS4 similarity to human PI P 5-kinaseYHR001w similarity to Kes1pYKR003w similarity to Kes1p, Hes1p and Osh1pYDL019c similarity to Osh1pYHR073w similarity to Osh1p, Hes1p, Kes1pYGR175c ERG1 squalene monooxygenaseYGL055w OLE1 stearoyl-CoA desaturaseYGL012w ERG4 sterol C-24 reductaseYLR372w SUR4 sterol isomeraseYKL192c strong similarity to acyl-carrier proteinsYNL045w strong similarity to human leukotriene-A4

hydrolase

bbrreeaakkddoowwnn ooff lliippiiddss aanndd pphhoosspphhoolliippiiddssYPL268w PLC1 1-phosphatidylinositol-4,5-bisphosphate

phosphodiesteraseYGL205w POX1 acyl-CoA oxidaseYMR008c PLB1 phospholipase B (lysophospholipase)YKR031c SPO14 phospholipase DYLR020c similarity to triacylglycerol lipaseYLL012w similarity to triacylglycerol lipasesYJL068c strong similarity to human esterase DYOL011w strong similarity to phospholipasesYMR006c strong similarity to Plb1pYKL140w TGL1 triacylglycerol lipaseYDR058c TGL2 triacylglycerol lipaseYJR107w weak similarity to acylglycerol lipaseYBR204c weak similarity to peroxisomal serine-

active lipase

lliippiidd,, ffaattttyy--aacciidd aanndd sstteerrooll uuttiilliizzaattiioonnYIL160c POT1 acetyl-CoA C-acyltransferase, peroxisomalYIL009w FAA3 acyl-CoA synthaseYMR013c SEC59 dolichol kinaseYDR331w GPI8 essential for GPI-anchor attachmentYDR410c STE14 farnesyl cysteine carboxyl-

methyltransferaseYPL172c COX10 farnesyl transferaseYOR370c MSI4 geranylgeranyltransferase regulatory

subunitYGL155w CDC43 geranylgeranyltransferase type I β subunitYPR176c BET2 geranylgeranyltransferase type II β subunitYJL031c BET4 geranylgeranyltransferase, α subunitYFL014w HSP12 heat-shock proteinYBR003w COQ1 hexaprenyl pyrophosphate synthetase YKR009c FOX2 hydratase-dehydrogenase-epimerase,

peroxisomalYOR317w FAA1 long-chain-fatty-acid-CoA ligaseYER015w FAA2 long-chain-fatty-acid-CoA ligaseYMR246w FAA4 long-chain-fatty-acid-CoA ligaseYDL078c MDH3 malate dehydrogenase, peroxisomalYLR195c NMT1 N-myristoyltransferaseYJR066w TOR1 phosphatidylinositol 3-kinaseYKL019w RAM2 protein farnesyltransferase, α subunitYDL090c RAM1 protein farnesyltransferase, β subunitYHR013c ARD1 protein N-acetyltransferase subunitYDL040c NAT1 protein N-acetyltransferase subunit

rreegguullaattiioonn ooff lliippiidd,, ffaattttyy--aacciidd aanndd sstteerrooll bbiioossyynntthheessiissYBL015w ACH1 acetyl-CoA hydrolaseYDR123c INO2 basic helix-loop-helix (BHLH) transcription

factorYOL108c INO4 basic helix-loop-helix transcription factor

YGL162w SUT1 hypoxic protein involved in sterol uptakeYMR208w ERG12 mevalonate kinaseYHL020c OPI1 negative regulator of phospholipid

biosynthesis pathwayYDR207c UME6 negative transcriptional regulatorYAL051w OAF1 peroxisome proliferating transcription

factorYOR363c PIP2 peroxisome proliferating transcription

factorYNL169c PSD1 phosphatidylserine decarboxylase 1YAL013w DEP1 regulator of phospholipid metabolismYMR207c HFA1 similarity to acetyl-CoA carboxylaseYCR028c FEN2 similarity to allantoate permease

transporterYMR043w MCM1 transcription factor of the MADS box

familyYOL004w SIN3 transcription regulatory protein

lliippiidd aanndd ffaattttyy--aacciidd ttrraannssppoorrttYGR037c ACB1 acyl-CoA-binding protein (diazepam-

binding inhibitor)YNL130c CPT1 diacylglycerol cholinephosphotransferaseYBR041w FAT1 fatty-acid transporterYKL188c PAT1 long-chain-fatty-acid transporterYPL147w PXA1 long-chain-fatty-acid transporterYOR317w FAA1 long-chain-fatty-acid-CoA ligaseYER015w FAA2 long-chain-fatty-acid-CoA ligaseYMR246w FAA4 long-chain-fatty-acid-CoA ligaseYAR035w YAT1 outer carnitine acetyltransferase,

mitochondrialYCL043c PDI1 protein disulphide-isomerase YER024w similarity to carnitine O-acetyltransferase

Yat1pYKL174c similarity to choline transport protein

Ctr1pYNR056c similarity to choline transport protein

Ctr1pYHR123w EPT1 sn-1,2-diacylglycerol ethanolamine- and

cholinephosphotransferase

lliippiidd aanndd ffaattttyy--aacciidd bbiinnddiinnggYHR001w similarity to Kes1pYMR020w FMS1 suppressor of fenpropimorph resistance

mutation fen2

ootthheerr lliippiidd,, ffaattttyy--aacciidd aanndd sstteerrooll mmeettaabboolliissmm aaccttiivviittiieessYBR036c CSG2 calcium dependent regulatory proteinYMR079w SEC14 phosphatidylinositol/phosphatidylcholine

transfer proteinYNL264c similarity to Sec14pYKL091c strong similarity to Sec14pYIL002c SJH1 synaptojanin homologue 1YDR302w weak similarity to human GPI-anchor

biosynthesis protein

biosynthesis of vitamins, cofactors andprosthetic groups

mmeettaabboolliissmm ooff vviittaammiinnss,, ccooffaaccttoorrss aanndd pprroosstthheettiicc ggrroouuppssYOL096c COQ3 3,4-dihydroxy-5-hexaprenylbenzoate

methyltransferaseYDR232w HEM1 5-aminolevulinate synthaseYOL143c RIB4 6,7-dimethyl-8-ribityllumazine synthaseYGR286c BIO2 biotin synthetaseYGR204w ADE3 C1-tetrahydrofolate synthase, cytoplasmicYBR084w MIS1 C1-tetrahydrofolate synthase,

mitochondrialYDR044w HEM13 coproporphyrinogen III oxidaseYPL132w COX11 cytochrome c oxidase assembly proteinYNR058w BIO3 DAPA aminotransferaseYDR487c RIB3 DBP synthaseYOL066c RIB2 DRAP deaminaseYPL172c COX10 farnesyl transferaseYOR176w HEM15 ferrochelatase YDL045c FAD1 flavin adenine dinucleotide (FAD)

synthetaseYGR267c FOL2 GTP cyclohydrolase IYBL033c RIB1 GTP cyclohydrolase IIYBR003w COQ1 hexaprenyl pyrophosphate synthetase YBR153w RIB7 HTP reductaseYOR196c LIP5 lipoic acid synthaseYHR042w NCP1 NADPH-cytochrome P450 reductaseYOR209c NPT1 nicotinate phosphoribosyltransferaseYNR033w ABZ1 para-aminobenzoate synthaseYNR041c COQ2 para-hydroxybenzoate-

polyprenyltransferaseYOR184w SER1 phosphoserine transaminaseYDL205c HEM3 porphobilinogen deaminaseYGL040c HEM2 porphobilinogen synthaseYER014w HEM14 protoporphyrinogen oxidase,

mitochondrialYNR057c BIO4 putative dethiobiotin synthetaseYBR035c PDX3 pyridoxamine-phosphate oxidaseYBR256c RIB5 riboflavin synthase, α subunitYER043c SAH1 S-adenosyl-L-homocysteine hydrolaseYNL256w similarity to bacterial dihydropteroate

synthaseYKL027w similarity to E. coli molybdopterin-

converting factor chlNYIL145c similarity to E. coli pantothenate

synthetaseYGR255c similarity to E. coli ubiH proteinYMR113w similarity to folylpolyglutamate

synthetases and strong similarity tohypothetical protein YKL132c

YGL125w similarity to humanmethylenetetrahydrofolate reductase


gazetteer

YPL023c similarity to humanmethylenetetrahydrofolate reductase

YFR047c similarity to human quinolinatephosphoribosyltransferase

YHR111w similarity to molybdopterin biosynthesisproteins

YOL151w similarity to plant dihydroflavonol-4-reductases

YMR222c similarity to S. pombe dihydrofolatereductase

YOR241w similarity to tetrahydrofolylpolyglutamatesynthase

YJR142w similarity to thiamin pyrophosphokinaseYKR069w similarity to uroporphyrinogen

methyltransferasesYGL039w similarity to V. vinifera dihydroflavonol

reductaseYBR176w strong similarity to E. coli 3-methyl-2-

oxobutanoate hydroxymethyltransferaseYHR003c strong similarity to molybdopterin-

converting factor homologue YKL027wYDL036c strong similarity to Rib2pYOL049w strong similarity to S. pombe Gsa1pYOR143c THI80 thiamin pyrophosphokinaseYPL214c THI6 thiamin-phosphate pyrophosphorylase

and hydroxyethylthiazole kinaseYDR047w HEM12 uroporphyrinogen decarboxylaseYOR278w HEM4 uroporphyrinogen III synthase

uuttiilliizzaattiioonn ooff vviittaammiinnss,, ccooffaaccttoorrss aanndd pprroosstthheettiicc ggrroouuppssYDL141w BPL1 biotin holocarboxylase synthetaseYBR092c PHO3 constitutive acid phosphatase YAL039c CYC3 holocytochrome c synthase (cytochrome

c haem lyase)YKL087c CYT2 holocytochrome c1 synthaseYML120c NDI1 NADH-ubiquinone-6 oxidoreductaseYBR093c PHO5 repressible acid phosphatase YKL132c similarity to B. subtilis folC protein and

strong similarity to hypothetical proteinYMR113w

rreegguullaattiioonn ooff vviittaammiinnss,, ccooffaaccttoorrss aanndd pprroosstthheettiicc ggrroouuppssYPR065w ROX1 haem-dependent transcriptional repressor

of hypoxic genesYOR125c CAT5 involved in glucose repression

ttrraannssppoorrtt ooff vviittaammiinnss,, ccooffaaccttoorrss aanndd pprroosstthheettiicc ggrroouuppssYIL134w FLX1 FAD carrier protein, mitochondrial (MCF)YIL006w similarity to Flx1p

ootthheerr vviittaammiinn,, ccooffaaccttoorr aanndd pprroosstthheettiicc--ggrroouupp aaccttiivviittiieessYDR541c similarity to dihydroflavonol-4-reductasesYGL157w similarity to E. gunnii cinnamyl alcohol

dehydrogenaseYER183c similarity to formyltetrahydrofolate cyclo-

ligaseYHL018w similarity to human pterin-4-—

carbinolamine dehydrataseYGR169c similarity to Rib2pYGR144w THI4 thiamine-repressed protein

ionic homeostasis

hhoommeeoossttaassiiss ooff mmeettaall iioonnssYNL259c ATX1 antioxidant protein and metal

homeostasis factorYJR049c UTR1 associated with ferric reductase activityYMR058w FET3 cell-surface ferroxidaseYOR316c COT1 cobalt accumulation proteinYPL177c CUP9 copper homeostasis proteinYDR515w SLF1 copper homeostasis proteinYPR124w CTR1 copper transport proteinYHR175w CTR2 copper transport proteinYLR411w CTR3 copper transport protein YGL166w CUP2 copper-dependent transcription factorYLR214w FRE1 ferric (and cupric) reductaseYKL220c FRE2 ferric (and cupric) reductaseYOR176w HEM15 ferrochelatase YGL255w ZRT1 high-affinity zinc-transport proteinYLL009c COX17 interacts genetically with SCO1 and SCO2

in cytochrome oxidase assemblyYBR037c SCO1 involved in stabilization of Cox1p and

Cox2pYGL071w RCS1 iron-regulated transcriptional repressorYLR130c ZRT2 low-affininty zinc transporterYMR319c FET4 low-affinity Fe(II) iron transport proteinYOL122c SMF1 manganese transporterYBR290w BSD2 metal homeostasis proteinYKL064w MNR2 overexpression overcomes manganese

toxicityYDR270w CCC2 probable copper-transporting ATPaseYBR295w PCA1 P-type Cu2+-transporting ATPaseYGL096w similarity to copper homeostasis protein

Cup9pYDR506c similarity to Fet3pYOL152w similarity to Fre1p and Fre2pYGL160w similarity to hypothetical protein YLR047c

and Fre2pYJR126c similarity to transferrin receptor proteinYFL041w strong similarity to cell-surface ferroxidase

Fet3pYLL051c strong similarity to ferric reductase Fre2pYOR381w strong similarity to ferric reductase Fre2pYOR384w strong similarity to ferric reductase Fre2pYNR060w strong similarity to Fre2p and hypothetical

protein YOR381w, and similarity to Fre1pYBR024w SCO2 strong similarity to Sco1p

YOR031w CRS5 suppressor of cup1 deletion,metallothionein-like protein

YCL037c SRO9 suppressor of rho3YMR243c ZRC1 zinc- and cadmium-resistance protein

hhoommeeoossttaassiiss ooff ootthheerr iioonnssYDL128w VCX1 Ca2+-transport (H+/Ca2+ exchange) protein,

vacuolarYGL006w PMC1 Ca2+-transporting P-type ATPaseYGL167c PMR1 Ca2+-transporting P-type ATPaseYGR217w CCH1 calcium channel proteinYLR348c dicarboxylate carrier proteinYKL016c ATP7 F1F0-ATPase complex, F0 D subunitYBL099w ATP1 F1F0-ATPase complex, F1 α subunitYJR121w ATP2 F1F0-ATPase complex, F1 β subunitYDL004w ATP16 F1F0-ATPase complex, F1 δ subunitYPL078c ATP4 F1F0-ATPase complex, F1 δ subunitYPL271w ATP15 F1F0-ATPase complex, F1 ε subunitYBR039w ATP3 F1F0-ATPase complex, F1 γ subunitYDR298c ATP5 F1F0-ATPase complex, OSCP subunitYLR295c ATP14 F1F0-ATPase complex, subunit hYCR024c-a PMP1 H+-ATPase subunit, plasma membraneYEL017c-a PMP2 H+-ATPase subunit, plasma membraneYMR054w STV1 H+-ATPase V0 domain 102K subunit,

vacuolar YHR039c-a VMA10 H+-ATPase V0 domain 13K subunit,

vacuolar YEL027w CUP5 H+-ATPase V0 domain 17K subunit,

vacuolar YPL234c TFP3 H+-ATPase V0 domain 17K subunit,

vacuolar YLR447c VMA6 H+-ATPase V0 domain 36K subunit,

vacuolar YOR270c VPH1 H+-ATPase V0 domain 95K subunit,

vacuolar YGR020c VMA7 H+-ATPase V1 domain 14K subunit,

vacuolar YOR332w VMA4 H+-ATPase V1 domain 27K subunit,

vacuolar YEL051w VMA8 H+-ATPase V1 domain 32K subunit,

vacuolar YKL080w VMA5 H+-ATPase V1 domain 42K subunit,

vacuolar YPR036w VMA13 H+-ATPase V1 domain 54K subunit,

vacuolar YBR127c VMA2 H+-ATPase V1 domain 60K subunit,

vacuolar YDL185w TFP1 H+-ATPase V1 domain 69K subunit,

vacuolar YGL008c PMA1 H+-transporting P-type ATPaseYPL036w PMA2 H+-transporting P-type ATPase 2YML123c PHO84 high affinity inorganic phosphate/H+

symporterYJL129c TRK1 high-affinity potassium transport proteinYBR294w SUL1 high-affinity sulphate transport proteinYJL117w PHO86 inorganic phospate transporterYLR220w CCC1 involved in calcium regulationYCR037c PHO87 member of the phosphate permease

familyYJL093c TOK1 outward-rectifier potassium channelYJR077c MIR1 phosphate transport protein,

mitochondrial (MCF)YEL031w SPF1 P-type ATPaseYDR040c ENA1 P-type ATPase involved in Na+ and Li+

effluxYDR039c ENA2 P-type ATPase involved in Na+ effluxYDR038c ENA5 P-type ATPase involved in Na+ effluxYLR138w NHA1 putative Na+/H+ antiporterYBR235w similarity to bumetanide-sensitive Na+-K+-

Cl- cotransport proteinYJL094c similarity to E. hirae Na+/H+-antiporter

NapAYNR013c similarity to membrane protein Pho87p

and hypothetical protein YJL198wYDR456w similarity to NA+/H+ antiportersYPR003c similarity to sulphate transporter proteinsYER053c strong similarity to mitochondrial


phosphate permeaseYLR092w SEL2 strong similarity to Sul1pYHL016c DUR3 urea transport proteinYJR040w GEF1 voltage-gated chloride channel protein

Energyglycolysis

YGR240c PFK1 6-phosphofructokinase, α subunitYMR205c PFK2 6-phosphofructokinase, β subunitYIL107c PFK26 6-phosphofructose-2-kinase, isoenzyme 1YOL136c PFK27 6-phosphofructose-2-kinase, isoenzyme 2YNL071w LAT1 dihydrolipoamide S-acetyltransferaseYGR254w ENO1 enolase I (2-phosphoglycerate

dehydratase)YHR174w ENO2 enolase II (2-phosphoglycerate

dehydratase)YOR393w ERR1 enolase-related proteinYPL281c ERR2 enolase-related proteinYKL060c FBA1 fructose-bisphosphate aldolase YBR196c PGI1 glucose-6-phosphate isomeraseYJL052w TDH1 glyceraldehyde-3-phosphate

dehydrogenase 1YJR009c TDH2 glyceraldehyde-3-phosphate

dehydrogenase 2

YGR192c TDH3 glyceraldehyde-3-phosphatedehydrogenase 3

YOL059w GPD3 glycerol-3-phosphate dehydrogenase(NAD+), mitochondrial

YFR053c HXK1 hexokinase IYGL253w HXK2 hexokinase IIYCR012w PGK1 phosphoglycerate kinaseYKL152c GPM1 phosphoglycerate mutaseYOL056w GPM3 phosphoglycerate mutaseYER178w PDA1 pyruvate dehydrogenase (lipoamide)



XYAL038w CDC19 pyruvate kinaseYLR345w similarity to 6-phosphofructo-2-kinaseYDL021w GPM2 strong similarity to phosphoglycerate

mutase Gpm1pYMR323w strong similarity to phosphopyruvate

hydratasesYOR347c strong similarity to pyruvate kinaseYKL029c strong similarity to S. pombe malate

oxireductaseYMR125w GCR3 transcription factor for glycolytic genesYDR050c TPI1 triose-phosphate isomeraseYKR043c weak similarity to phosphoglycerate

mutaseYOR283w weak similarity to phosphoglycerate

mutases

gluconeogenesis

YOR393w ERR1 enolase-related proteinYPL281c ERR2 enolase-related proteinYLR377c FBP1 fructose-1,6-bisphosphataseYBR196c PGI1 glucose-6-phosphate isomeraseYER065c ICL1 isocitrate lyaseYKR097w PCK1 phosphoenolpyruvate carboxykinaseYCR012w PGK1 phosphoglycerate kinaseYGL062w PYC1 pyruvate carboxylase 1YBR218c PYC2 pyruvate carboxylase 2YIL167w SDL1 serine dehydrataseYOR347c strong similarity to pyruvate kinaseYMR280c CAT8 transcription factor involved in

gluconeogenesisYDR050c TPI1 triose-phosphate isomerase

pentose-phosphate pathway

YHR183w GND1 6-phosphogluconate dehydrogenaseYOR095c RKI1 D-ribose-5-phosphate ketol-isomeraseYJL121c POS18 D-ribulose-5-phosphate 3-epimeraseYNL241c ZWF1 glucose-6-phosphate dehydrogenaseYGR256w GND2 phosphogluconate dehydrogenaseYGR043c strong similarity to transaldolaseYLR354c TAL1 transaldolaseYPR074c TKL1 transketolase 1YBR117c TKL2 transketolase 2

tricarboxylic-acid pathway

YIL125w KGD1 2-oxoglutarate dehydrogenase complexE1 component

YDR148c KGD2 2-oxoglutarate dehydrogenase complexE2 component

YLR304c ACO1 aconitate hydrataseYNR001c CIT1 citrate (si)-synthase, mitochondrialYPR001w CIT3 citrate (si)-synthase, mitochondrialYFL018c LPD1 dihydrolipoamide dehydrogenase YPL262w FUM1 fumarate hydrataseYNL009w homology to isocitrate dehydrogenaseYNL037c IDH1 isocitrate dehydrogenase (NAD+)

subunit 1, mitochondrialYOR136w IDH2 isocitrate dehydrogenase (NAD+)

subunit 2, mitochondrialYLR174w IDP2 isocitrate dehydrogenase, cytosolicYOL126c MDH2 malate dehydrogenase, cytoplasmicYOR297c similarity to SDH4 proteinYJL200c strong similarity to aconitate hydrataseYGR244c strong similarity to rumen fungus

β-succinyl-CoA synthetaseYLR164w strong similarity to Sdh4pYMR118c strong similarity to succinate

dehydrogenaseYJL045w strong similarity to succinate

dehydrogenase flavoproteinYOR142w strong similarity to succinate-CoA ligase

α subunitYKL148c SDH1 succinate dehydrogenase flavoprotein YLL041c SDH2 succinate dehydrogenase iron-sulphur

protein subunitYDR178w SDH4 succinate dehydrogenase membrane

anchor subunit for Sdh2p

respiration

YMR282c AEP2 2’-O-ribosyl phosphate transferaseYGR008c STF2 ATPase stabilizing factorYDL130w-a STF1 ATPase stabilizing factor, 10KYDR377w ATP17 ATPase synthase subunit fYER061c CEM1 β-keto-acyl-ACP synthaseYIL043c CBR1 cytochrome b5 reductaseYKL150w MCR1 cytochrome b5 reductaseYKL141w SDH3 cytochrome b560 subunit of respiratory

complex IIYJR048w CYC1 cytochrome c isoform 1YEL039c CYC7 cytochrome c isoform 2


gazetteer

YML129c COX14 cytochrome c oxidase assembly proteinYDR079w PET100 cytochrome c oxidase assembly proteinYGL187c COX4 cytochrome c oxidase subunit IVYNL052w COX5A cytochrome c oxidase subunit V.A YIL111w COX5B cytochrome c oxidase subunit VbYHR051w COX6 cytochrome c oxidase subunit VIYGL191w COX13 cytochrome c oxidase subunit VIaYLR038c COX12 cytochrome c oxidase subunit VIBYMR256c COX7 cytochrome c oxidase subunit VIIYDL067c COX9 cytochrome c oxidase subunit VIIAYLR395c COX8 cytochrome c oxidase subunit VIIIYOR065w CYT1 cytochrome c1YER154w OXA1 cytochrome oxidase biogenesis proteinYGR207c ETF-β electron-transferring flavoprotein,

β subunitYKL016c ATP7 F1F0-ATPase complex, F0 D subunitYBL099w ATP1 F1F0-ATPase complex, F1 α subunitYJR121w ATP2 F1F0-ATPase complex, F1 β subunitYDL004w ATP16 F1F0-ATPase complex, F1 δ subunitYPL078c ATP4 F1F0-ATPase complex, F1 δ subunitYPL271w ATP15 F1F0-ATPase complex, F1 ε subunitYBR039w ATP3 F1F0-ATPase complex, F1 γ subunitYDR298c ATP5 F1F0-ATPase complex, OSCP subunitYLR295c ATP14 F1F0-ATPase complex, subunit hYEL053c MAK10 glucose-repressible proteinYLL009c COX17 interacts genetically with SCO1 and SCO2

in cytochrome oxidase assemblyYJR034w PET191 involved in assembly of cytochrome

oxidaseYMR165c SMP2 involved in plasmid maintenance,

respiration and cell proliferationYML054c CYB2 lactate dehydrogenase cytochrome b2YBR192w RIM2 mitochondrial carrier protein (MCF)YMR089c YTA12 protease of the SEC18/CDC48/PAS1

family of ATPases (AAA)YLR044c PDC1 pyruvate decarboxylase, isozyme 1YGR062c COX18 required for activity of mitochondrial

cytochrome oxidaseYBR185c MBA1 respiratory chain assembly proteinYDL107w MSS2 ser/thr protein kinaseYPR048w similarity to M. domestica NADPH-

ferrihemoprotein reductase andmammalian nitric-oxide synthases

YGL226w similarity to N. crassa cytochrome coxidase subunit V

YMR244w similarity to NCA3 and SUN4 proteinYML087c strong similarity to cytochrome b5- and

nitrate reductasesYML125c strong similarity to cytochrome b5- and

nitrate reductasesYPR004c strong similarity to electron transfer

flavoproteins α subunitYOR356w strong similarity to human electron

transfer flavoprotein-ubiquinoneoxidoreductase

YDL085w strong similarity to NADH dehydrogenase(ubiquinone)

YMR145c strong similarity to NADH dehydrogenase(ubiquinone)

YDL080c strong similarity to pyruvatedecarboxylases

YDR178w SDH4 succinate dehydrogenase membraneanchor subunit for Sdh2p

YNL118c PSU1 suppressor protein of a yeast pet mutantYFR033c QCR6 ubiquinol-cytochrome c reductase 17K

proteinYPR191w QCR2 ubiquinol-cytochrome c reductase 40K

subunit IIYBL045c COR1 ubiquinol-cytochrome c reductase 44K

core proteinYHR001w-a QCR10 ubiquinol-cytochrome c reductase 8.5K

subunitYGR174c CBP4 ubiquinol-cytochrome c reductase

assembly factorYGL119w ABC1 ubiquinol-cytochrome c reductase

complex assembly proteinYEL024w RIP1 ubiquinol-cytochrome c reductase iron-

sulphur protein YDR529c QCR7 ubiquinol-cytochrome c reductase

subunit 7YGR183c QCR9 ubiquinol-cytochrome c reductase

subunit 9YJL166w QCR8 ubiquinol-cytochrome c reductase

subunit VIIIYMR073c weak similarity to C-terminal part of

cytochrome b5 and b2YNL237w YTP1 weak similarity to mitochondrial electron

transport proteins

fermentation

YOL086c ADH1 alcohol dehydrogenase IYMR303c ADH2 alcohol dehydrogenase IIYMR083w ADH3 alcohol dehydrogenase IIIYGL256w ADH4 alcohol dehydrogenase IVYBR145w ADH5 alcohol dehydrogenase VYER073w aldehyde dehydrogenase (NAD+)YPL061w ALD6 aldehyde dehydrogenase, cytosolicYDL174c DLD1 D-lactate ferricytochrome c

oxidoreductase (D-LCR)YML004c GLO1 glyoxalase IYOR126c EST2 isoamyl acetate hydrolytic enzymeYPL275w putative formate dehydrogenase/putative

pseudogeneYPL276w putative formate dehydrogenase/putative

pseudogeneYDR081c PDC2 pyruvate decarboxylase regulatory proteinYLR044c PDC1 pyruvate decarboxylase, isozyme 1

YLR134w PDC5 pyruvate decarboxylase, isozyme 2YGR087c PDC6 pyruvate decarboxylase, isozyme3YAL060w FUN49 similarity to alcohol/sorbitol

dehydrogenaseYAL061w FUN50 similarity to alcohol/sorbitol

dehydrogenaseYMR318c similarity to alcohol-dehydrogenaseYHR039c similarity to aldehyde dehydrogenasesYPL088w similarity to aryl-alcohol dehydrogenasesYMR285c similarity to Ccr4pYHL008c similarity to M. formicicum formate

dehydrogenaseYKR096w similarity to mitochondrial aldehyde

dehydrogenase Ald1pYDR380w similarity to pyruvate decarboxylasesYNL331c strong similarity aryl-alcohol reductaseYCR107w strong similarity aryl-alcohol reductasesYCR105w strong similarity to alcohol

dehydrogenasesYMR169c ALD4 strong similarity to aldehyde

dehydrogenaseYDL243c strong similarity to aryl-alcohol

dehydrogenaseYJR155w strong similarity to aryl-alcohol

dehydrogenaseYFL056c strong similarity to aryl-alcohol

dehydrogenasesYFL057c strong similarity to aryl-alcohol

dehydrogenasesYOL165c strong similarity to aryl-alcohol

dehydrogenasesYOR388c strong similarity to H. polymorpha formate

dehydrogenase

metabolism of energy reserves (glycogen andtrehalose)

YEL011w GLC3 1,4-glucan branching enzyme (glycogenbranching enzyme)

YBR001c NTH2 α,α-trehalaseYDR074w TPS2 α,α-trehalose-phosphate synthase, 105K

subunitYMR261c TPS3 α,α-trehalose-phosphate synthase, 115K

subunitYML100w TSL1 α,α-trehalose-phosphate synthase, 123K


subunitYPR026w ATH1 acid trehalase, vacuolarYBR299w MAL32 α-glucosidaseYHR047c AAP1 alanine/arginine aminopeptidaseYPL031c PHO85 cyclin-dependent protein kinaseYLR071c RGR1 DNA-directed RNA polymerase II

holoenzyme subunitYER054c GIP2 Glc7p-interacting proteinYBR229c ROT2 glucosidase II, catalytic subunitYPR160w GPH1 glycogen phosphorylaseYPL240c HSP82 heat-shock proteinYKL128c PMU1 high copy suppressor of ts tps2 mutant

phenotypeYDR001c NTH1 neutral trehalase (α,α-trehalase)YMR105c PGM2 phosphoglucomutase, major isoformYKL127w PGM1 phosphoglucomutase, minor isoformYNR032w PPG1 phosphoprotein phosphatase PPG

catalytic subunitYBL058w SHP1 potential regulatory subunit for Glc7pYLR273c PIG1 protein interacting with Gsy2pYIL045w PIG2 protein interacting with Gsy2pYJL137c GLG2 self-glucosylating initiator of glycogen

synthesisYKR058w GLG1 self-glycosylating initiator of glycogen

synthesisYER133w GLC7 ser/thr phosphoprotein phosphatase 1,


regulatory subunit YPR184w similarity to glycogen debranching

enzymesYJL221c FSP2 strong similarity to α-D-glucosidaseYOL157c strong similarity to α-glucosidasesYIL172c strong similarity to Fsp2pYJL216c strong similarity to Mal62pYFR015c GSY1 UDP glucose-starch glucosyltransferase,

isoform 1YLR258w GSY2 UDP-glucose-starch glucosyltransferase,

isoform 2YKL035w UGP1 UTP-glucose-1-phosphate

uridylyltransferase

other energy-generation activities

YIL160c POT1 acetyl-CoA C-acyltransferase, peroxisomalYGL205w POX1 acyl-CoA oxidaseYMR170c ALD5 aldehyde dehydrogenase 2 (NAD+),

mitochondrialYML035c AMD1 AMP deaminaseYCR005c CIT2 citrate (si)-synthase, peroxisomalYKR009c FOX2 hydratase-dehydrogenase-epimerase,

peroxisomalYMR267w PPA2 inorganic pyrophosphatase, mitochondrialYDL066w IDP1 isocitrate dehydrogenase (NADP+),

mitochondrialYER065c ICL1 isocitrate lyaseYKL085w MDH1 malate dehydrogenase, mitochondrialYDL078c MDH3 malate dehydrogenase, peroxisomalYNL117w MLS1 malate synthase 1YIR031c DAL7 malate synthase 2

YHR179w OYE2 NAPDH dehydrogenase (old yellowenzyme), isoform 1

YPL171c OYE3 NAPDH dehydrogenase (old yellowenzyme), isoform 3

YPR006c ICL2 non-functional isocitrate lyaseYOL079w similarity to NADH dehydrogenaseYEL020c similarity to O. formigenes oxalyl-CoA

decarboxylaseYDR384c strong similarity to Y. lipolytica GPR1

gene

Cell growth, cell division andDNA synthesiscell growth

YPL268w PLC1 1-phosphatidylinositol-4,5-bisphosphatephosphodiesterase

YCR088w ABP1 actin-binding proteinYDL029w ACT2 actin-like proteinYOL052c SPE2 adenosylmethionine decarboxylase YNL138w SRV2 adenylate cyclase-associated protein, 70KYER170w ADK2 adenylate kinase, mitochondrialYBR109c CMD1 calmodulinYHR135c YCK1 casein kinase I isoformYNL154c YCK2 casein kinase I isoformYJL174w KRE9 cell-wall synthesis proteinYNL327w EGT2 cell-cycle regulation proteinYLR175w CBF5 centromere/microtubule binding proteinYGR167w CLC1 clathrin light chainYDR251w PAM1 coiled-coil protein multicopy suppressor

of loss of PP2AYBL007c SLA1 cytoskeleton assembly control proteinYFL001w DEG1 depressed growth-rate proteinYLR300w EXG1 exo-1,3-—glucanase (I/II), major isoformYDR261c EXG2 exo-1,3-—glucanase minor isoformYPR159w KRE6 glucan synthase subunitYBR212w NGR1 glucose-repressible RNA-binding proteinYOR043w WHI2 growth regulation proteinYKL021c MAK11 involved in cell growth and replication of

M1 dsRNA virusYMR165c SMP2 involved in plasmid maintenance,

respiration and cell proliferationYNL197c WHI3 involved in regulation of cell sizeYDR293c SSD1 involved in the tolerance to high

concentration of Ca2+

YOR336w KRE5 killer toxin-resistance proteinYDR480w DIG2 MAP kinase-associated proteinYJR032w CPR7 member of the cyclophilin familyYGR029w ERV1 mitochondrial biogenesis and cell viability

proteinYBR089c-a NHP6B nonhistone chromosomal proteinYPR052c NHP6A nonhistone chromosomal protein related

to mammalian HMG1YKL203c TOR2 phosphatidylinositol 3-kinaseYCR034w GNS1 probable 1,3-—glucan synthase subunitYOR149c SMP3 protein kinase C pathway proteinYPL140c MKK2 protein kinase of the MAP kinase kinase

(MEK) familyYDR151c CTH1 protein of the inducible CCCH zinc-finger

familyYDR075w PPH3 protein ser/thr phosphataseYDL006w PTC1 protein ser/thr phosphatase 2cYDL134c PPH21 protein ser/thr phosphatase PP2A-1YDL188c PPH22 protein ser/thr phosphatase PP2A-2YDR137w RGP1 reduced growth phenotype proteinYJR090c GRR1 required for glucose repression and for

glucose and cation transportYGL190c CDC55 ser/thr phosphatase 2A regulatory

subunit BYAL016w TPD3 ser/thr phosphatase 2A, regulatory

subunit AYOR231w MKK1 ser/thr protein kinaseYPR161c SGV1 ser/thr protein kinaseYHR030c SLT2 ser/thr protein kinase of MAP kinase

familyYJL095w BCK1 ser/thr protein kinase of the MEKK familyYER167w BCK2 ser/thr protein kinase of the protein

kinase C pathwayYNL180c similarity to S. pombe Cdc42p and other

GTP-binding proteinsYOR027w STI1 stress-induced proteinYGL106w strong similarity to calmodulinsYER177w BMH1 strong similarity to mammalian 14-3-3

proteinsYPL032c strong similarity to Pam1pYKL161c strong similarity to ser/thr-specific protein

kinase Slt2pYDL224c strong similarity to WHI3 proteinYDR099w BMH2 suppressor of clathrin deficiencyYJR075w HOC1 suppressor of pkc1YOR075w UFE1 syntaxin (T-SNARE) of the ERYHR206w SKN7 transcription factor with similarity to Hsf1pYNL079c TPM1 tropomyosin 1YLR337w VRP1 verprolinYLR403w SFP1 zinc-finger protein

budding, cell polarity and filament formation

YFL039c ACT1 actinYDR129c SAC6 actin filament bundling protein, fimbrinYCR088w ABP1 actin-binding proteinYDL029w ACT2 actin-like proteinYNL138w SRV2 adenylate cyclase-associated protein, 70KYOR304c-a BAT2 AIP3 binding protein


gazetteer

YBL085w BOI1 BEM1 protein-binding proteinYBR200w BEM1 bud emergence mediatorYPL161c BEM4 bud emergence proteinYDR351w SBE2 bud growth proteinYLR319c BUD6 bud site selection proteinYNL271c BNI1 budding proteinYER114c BOI2 budding proteinYJR092w BUD4 budding proteinYLR353w BUD8 budding proteinYGR041w BUD9 budding proteinYBR109c CMD1 calmodulinYHR135c YCK1 casein kinase I isoformYNL154c YCK2 casein kinase I isoformYPL255w BBP1 cell division control proteinYDR182w CDC1 cell division control proteinYLR314c CDC3 cell division control proteinYFL009w CDC4 cell division control proteinYJL174w KRE9 cell-wall synthesis proteinYBR038w CHS2 chitin synthase IIYBR023c CHS3 chitin synthase IIIYLR330w CHS5 chitin synthesis proteinYLL050c COF1 cofilin, actin binding and severing proteinYDR251w PAM1 coiled-coil protein multicopy suppressor

of loss of PP2AYPL256c CLN2 cyclin, G1/S specificYBR160w CDC28 cyclin-dependent protein kinaseYNL243w SLA2 cytoskeleton assembly control proteinYLR071c RGR1 DNA-directed RNA polymerase II

holoenzyme subunitYKL007w CAP1 F-actin capping protein, α subunitYIL034c CAP2 F-actin capping protein, β subunitYJL157c FAR1 factor arrest proteinYAL041w CDC24 GDP/GTP exchange factor for Cdc42pYCR038c BUD5 GDP/GTP exchange factor for

Rsr1p/Bud1pYGR070w ROM1 GDP/GTP exchange protein for Rho1pYLR371w ROM2 GDP/GTP exchange protein for Rho1pYGL155w CDC43 geranylgeranyltransferase type I β subunitYER155c BEM2 GTPase-activating proteinYKL092c BUD2 GTPase-activating protein for

Bud1p/Rsr1pYPL115c BEM3 GTPase-activating protein for Cdc42p and

Rho1pYGR152c RSR1 GTP-binding proteinYLR229c CDC42 GTP-binding protein of RAS superfamilyYIL118w RHO3 GTP-binding protein of the RHO familyYKR055w RHO4 GTP-binding protein of the RHO familyYPR165w RHO1 GTP-binding protein of the RHO subfamily


of RAS-like proteinsYOR156c NFI1 interacts with Cdc12p in 2-hybrid assayYKR063c LAS1 involved in cell morphogenesis,

cytoskeletal regulation and bud formationYLL021w SPA2 involved in cell polarityYDR085c AFR1 involved in morphogenesis of the mating

projectionYMR273c ZDS1 involved in negative regulation of cell

polarityYER149c PEA2 involved in oriented growth towards

mating partnerYDR293c SSD1 involved in the tolerance to high


YKL079w SMY1 kinesin-related proteinYOR198c BFR1 maintenance of normal ploidyYJL158c member of the Pir1p/Hsp150p/Pir3p

familyYJL159w member of the Pir1p/Hsp150p/Pir3p

familyYJL160c member of the Pir1p/Hsp150p/Pir3p

familyYOR188w MSB1 morphogenesis-related proteinYGR014w MSB2 multicopy suppressor of a cdc24 bud

emergence defectYHR023w MYO1 myosin 1 isoform (type II myosin) heavy

chainYOR326w MYO2 myosin heavy chainYAL029c MYO4 myosin heavy chain, unconventional

(class V) isoformYMR109w MYO5 myosin IYKL129c MYO3 myosin type IYBR089c-a NHP6B nonhistone chromosomal proteinYPR052c NHP6A nonhistone chromosomal protein related

to mammalian HMG1YCR057c PWP2 periodic tryptophan proteinYBL058w SHP1 potential regulatory subunit for Glc7pYCR034w GNS1 probable 1,3-—glucan synthase subunitYER108c FLO8 probable transcriptional activator of Flo1pYOR122c PFY1 profilinYPR122w AXL1 proteaseYOR149c SMP3 protein kinase C pathway proteinYPL140c MKK2 protein kinase of the MAP kinase kinase

(MEK) familyYDL047w SIT4 protein ser/thr phosphataseYDL006w PTC1 protein ser/thr phosphatase 2cYDL134c PPH21 protein ser/thr phosphatase PP2A-1YDL188c PPH22 protein ser/thr phosphatase PP2A-2YDR388w RVS167 reduced viability upon starvation proteinYMR016c SOK2 regulatory protein in the PKA signal

transduction pathwayYCL014w BUD3 required for axial buddingYIL140w SRO4 required for axial pattern of buddingYER109c FLO8 required for diploid filamentous growthYNL084c END3 required for endocytosis and cytoskeletal

organizationYJR090c GRR1 required for glucose repression and for

glucose and cation transport

YDL135c RDI1 RHO GDP dissociation inhibitor withactivity toward Rho1p

YOR127w RGA1 RHO-type GTPase-activating protein forCdc42p

YKL181w PRPS1 ribose-phosphate pyrophosphokinaseYJR076c CDC11 septinYHR107c CDC12 septinYGL190c CDC55 ser/thr phosphatase 2A regulatory


subunit AYER133w GLC7 ser/thr phosphoprotein phosphatase 1,


regulatory subunit YKL048c ELM1 ser/thr protein kinaseYOR231w MKK1 ser/thr protein kinaseYBL105c PKC1 ser/thr protein kinaseYHR030c SLT2 ser/thr protein kinase of MAP kinase

familyYJL095w BCK1 ser/thr protein kinase of the MEKK familyYLR362w STE11 ser/thr protein kinase of the MEKK familyYER167w BCK2 ser/thr protein kinase of the protein

kinase C pathwayYDL159w STE7 ser/thr/tyr protein kinase of MAP kinase

kinase familyYDL225w similarity to Cdc11p, Cdc3p and human

CDC10 proteinYGL054c similarity to D. melanogaster cni proteinYCR009c RVS161 similarity to human amphiphysin and

Rvs167pYDR208w MSS4 similarity to human PI P 5-kinaseYDR409w similarity to Nfi1pYDL125c YHI1 similarity to protein kinase C inhibitor-IYDR245w MNN10 similarity to S. pombe

galactosyltransferaseYFR040w SAP155 Sit4p-associated proteinYKR028w SAP190 Sit4p-associated proteinYJL098w SAP185 Sit4p-associating proteinYLR372w SUR4 sterol isomeraseYHR103w SBE22 strong similarity to budding protein Sbe2pYGL106w strong similarity to calmodulinsYBR210w strong similarity to D. melanogaster

cornichon proteinYPL032c strong similarity to Pam1pYNL320w strong similarity to S. pombe Bem46pYKL161c strong similarity to ser/thr-specific protein

kinase Slt2pYBR161w strong similarity to Sur1pYJR075w HOC1 suppressor of pkc1YDR297w SUR2 suppressor of rvs161 and rvs167

mutationsYPL057c SUR1 suppressor of rvs161, rvs167, and cls2

mutationsYKL043w PHD1 transcription factorYGL181w GTS1 transcription factor of the

Gcs1p/Glo3p/Sps18p familyYHR084w STE12 transcriptional activatorYNL079c TPM1 tropomyosin 1YIL138c TPM2 tropomyosin 2YBR083w TEC1 Ty transcription activatorYGL095c VPS45 vacuolar protein sorting-associated

proteinYLR337w VRP1 verprolin

pheromone response and mating-typedetermination

YJR004c SAG1 α-agglutininYNR044w AGA1 α-agglutinin anchor subunitYGL032c AGA2 α-agglutinin binding subunitYDR264c AKR1 ankyrin repeat-containing proteinYKL209c STE6 ATP-binding cassette transporter proteinYIL015w BAR1 barrier pepsin YBR200w BEM1 bud emergence mediatorYPL161c BEM4 bud emergence proteinYML057w CMP2 calcineurin B, catalytic subunitYLR433c CNA1 calcineurin B, catalytic subunitYKL190w CNB1 calcineurin B, regulatory subunitYBR109c CMD1 calmodulinYCR002c CDC10 cell division control proteinYLR314c CDC3 cell division control proteinYNL188w KAR1 cell division control proteinYCL027w FUS1 cell fusion proteinYJL174w KRE9 cell-wall synthesis proteinYNL192w CHS1 chitin synthase IYBR023c CHS3 chitin synthase IIIYLR330w CHS5 chitin synthesis proteinYDR073w SNF11 component of SWI/SNF transcription




activator complexYPL256c CLN2 cyclin, G1/S specificYNL243w SLA2 cytoskeleton assembly control proteinYER095w RAD51 DNA repair proteinYDR076w RAD55 DNA repair proteinYDR004w RAD57 DNA repair proteinYAR007c RFA1 DNA replication factor A, 69K subunitYOL051w GAL11 DNA-directed RNA polymerase II




YNL053w MSG5 dual-specifity protein phosphataseYNL238w KEX2 endoproteinase of late Golgi

compartmentYLR300w EXG1 exo-1,3-—glucanase (I/II), major isoformYDR261c EXG2 exo-1,3-—glucanase minor isoformYKL007w CAP1 F-actin capping protein, α subunitYIL034c CAP2 F-actin capping protein, β subunitYJL157c FAR1 factor arrest proteinYAL041w CDC24 GDP/GTP exchange factor for Cdc42pYGL097w SRM1 GDP/GTP exchange factor for

Gsp1p/Gsp2pYNL236w SIN4 global regulator proteinYHL025w SNF6 global transcription activatorYKL104c GFA1 glucosamine-fructose-6-phosphate

transaminaseYPL115c BEM3 GTPase-activating protein for Cdc42p and

Rho1pYHR005c GPA1 GTP-binding protein α subunit of the

pheromone pathwayYOR212w STE4 GTP-binding protein β subunit of the

pheromone pathwayYJR086w STE18 GTP-binding protein γ subunit of the

pheromone pathwayYLR229c CDC42 GTP-binding protein of RAS superfamilyYNL173c MDG1 GTP-binding protein of the pheromone

pathwayYER020w GPA2 guanine nucleotide-binding regulatory

proteinYDL227c HO homothallic switching endonucleaseYNL291c MID1 involved in Ca2+ influx during matingYLL021w SPA2 involved in cell polarityYLR452c SST2 involved in desensitization to α-factor

pheromoneYDR085c AFR1 involved in morphogenesis of the mating

projectionYER149c PEA2 involved in oriented growth toward mating

partnerYMR052w FAR3 involved in pheromone-mediated cell

cycle arrestYMR127c SAS2 involved in silencing at HMRYPR141c KAR3 kinesin-related proteinYPL187w MFα1 mating pheromone α-1 factorYGL089c MFα2 mating pheromone α-2 factorYDR461w MFA1 mating pheromone a-factor 1YNL145w MFA2 mating pheromone a-factor 2YLR332w MID2 mating process proteinYHR066w SSF1 mating proteinYDR143c SAN1 mating type regulatory proteinYCR040w MATα1 mating type regulatory protein (expressed

copy at MAT locus)YCR039c MATα2 mating type regulatory protein (expressed

copy at MAT locus)YCL066w α1 mating type regulatory protein (silenced

copy at HML locus)YCL067c α2 mating type regulatory protein (silenced

copy at HML locus)YCR097w A1 mating type regulatory protein (silenced

copy at HMR locus)YCR096c A2 mating type regulatory protein (silenced

copy at HMR locus)YIL047c SYG1 member of the major facilitator

superfamilyYBL016w FUS3 mitogen-activated protein kinase (MAP

kinase)YGL151w NUT1 negative regulator of HO endonucleaseYPR168w NUT2 negative regulator of HO endonucleaseYKL185w ASH1 negative regulator of HO expressionYCL029c BIK1 nuclear fusion proteinYML065w ORC1 origin recognition complex, 104K subunitYNL261w ORC5 origin recognition complex, 50K subunitYHR118c ORC6 origin recognition complex, 50K subunitYPR162c ORC4 origin recognition complex, 56K subunitYLL004w ORC3 origin recognition complex, 62K subunitYBR060c RRR1 origin recognition complex, 72K subunitYFL026w STE2 pheromone α-factor receptorYKL178c STE3 pheromone α-factor receptorYCL032w STE50 pheromone response pathway proteinYDR103w STE5 pheromone signal transduction pathway

proteinYCR034w GNS1 probable 1,3-—glucan synthase subunitYLR389c STE23 protease involved in α-factor processingYML032c RAD52 recombination and DNA repair proteinYDR392w SPT3 regulatory proteinYCL055w KAR4 regulatory protein required for pheromone

induction of karyogamy genesYMR232w FUS2 required for cell fusion during matingYBR040w FIG1 required for efficient matingYCR089w FIG2 required for efficient matingYNL084c END3 required for endocytosis and cytoskeletal

organizationYKL130c SHE2 required for mother cell-specific

expression of HOYOR035c SHE4 required for mother cell-specific gene

expressionYOR127w RGA1 RHO-type GTPase-activating protein for

Cdc42pYLR441c RP10A ribosomal protein S3a.eYJR076c CDC11 septinYHR107c CDC12 septinYPR161c SGV1 ser/thr protein kinaseYGR040w KSS1 ser/thr protein kinase of the MAP kinase

familyYLR362w STE11 ser/thr protein kinase of the MEKK familyYHL007c STE20 ser/thr protein kinase of the pheromone

pathway


gazetteer

YDL159w STE7 ser/thr/tyr protein kinase of MAP kinasekinase family

YOL068c HST1 silencing proteinYBL052c SAS3 silencing proteinYKR101w SIR1 silencing regulatory proteinYDL042c SIR2 silencing regulatory proteinYLR442c SIR3 silencing regulatory proteinYDR227w SIR4 silencing regulatory proteinYNL283c similarity to a-agglutinin core protein

Aga1pYDL225w similarity to Cdc11p, Cdc3p and human

CDC10 proteinYDR191w HST4 similarity to Hst3p,Hst1p and Sir2pYGR023w similarity to Mid2pYHR146w similarity to pheromone-response G-

protein YNL173cYKL117w Ste5p-associated proteinYGL106w strong similarity to calmodulinsYJL212c strong similarity to S. pombe isp4 proteinYDR312w SSF2 strong similarity to SSF1 proteinYPL129w ANC1 TFIIF subunit (transcription initiation

factor), 30KYDR146c SWI5 transcription factorYMR043w MCM1 transcription factor of the MADS box

familyYNL330c RPD3 transcription modifier proteinYOL004w SIN3 transcription regulatory proteinYJL176c SWI3 transcription regulatory proteinYHR084w STE12 transcriptional activatorYER068w MOT2 transcriptional repressorYNL079c TPM1 tropomyosin 1YOR219c STE13 type IV dipeptidyl aminopeptidaseYMR022w QRI8 ubiquitin-conjugating enzymeYBR082c UBC4 ubiquitin-conjugating enzymeYDR059c UBC5 ubiquitin-conjugating enzymeYER100w UBC6 ubiquitin-conjugating enzymeYJR117w STE24 zinc metallo-protease

sporulation and germination

YGR032w GSC2 1,3-—D-glucan synthase, subunitYPR103w PRE2 26S proteasome subunitYGR253c PUP2 26S proteasome subunitYBL015w ACH1 acetyl-CoA hydrolaseYCR048w ARE1 acyl-CoA sterol acyltransferaseYNR019w ARE2 acyl-CoA sterol acyltransferaseYOL052c SPE2 adenosylmethionine decarboxylase YDR173c ARG82 arginine metabolism transcription factorYIL033c SRA1 cAMP dependent protein kinase,

regulatory subunitYDR182w CDC1 cell division control proteinYFL009w CDC4 cell division control proteinYNL192w CHS1 chitin synthase IYBR023c CHS3 chitin synthase IIIYDR402c DIT2 cytochrome P450 56YML110c DBI56 DBF2 interacting proteinYOL051w GAL11 DNA-directed RNA polymerase II



YMR013c SEC59 dolichol kinaseYOR190w SPR1 exo-1,3-—glucanase YLR300w EXG1 exo-1,3-—glucanase (I/II), major isoformYDR261c EXG2 exo-1,3-—glucanase minor isoformYBR045c GIP1 Glc7p-interacting proteinYNL236w SIN4 global regulator proteinYDL240w LRG1 GTPase-activating protein of the

RHO/RAC familyYNL098c RAS2 GTP-binding proteinYPL240c HSP82 heat-shock proteinYJL146w IDS2 IME2-dependent signaling proteinYER044c-a MEI4 meiosis-specific proteinYBR057c MUM2 meiotic proteinYAL009w SPO7 meiotic proteinYLR025w SNF7 nuclear proteinYKR031c SPO14 phospholipase DYGL192w IME4 positive transcription factor for IME2YCR034w GNS1 probable 1,3-—glucan synthase subunitYIR026c YVH1 protein tyrosine phosphataseYOR208w PTP2 protein-tyrosine-phosphataseYBL066c SEF1 putative transcription factorYNR052c POP2 required for glucose derepressionYDR218c SPR28 septin-related sporulation proteinYJL106w IME2 ser/thr protein kinaseYDR523c SPS1 ser/thr protein kinaseYNL307c MCK1 ser/thr/tyr protein kinaseYDR403w DIT1 spore-wall maturation proteinYBR148w YSW1 spore-specific proteinYKL165c sporulation proteinYLR399c BDF1 sporulation proteinYHR152w SPO12 sporulation proteinYHR153c SPO16 sporulation proteinYIL099w SGA1 sporulation specific glucan

1,4-—glucosidaseYDR108w GSG1 sporulation-specific proteinYER096w SHC1 sporulation-specific proteinYLR307w CDA1 sporulation-specific chitin deacetylaseYLR308w CDA2 sporulation-specific chitin deacetylaseYPR054w SMK1 sporulation-specific MAP kinaseYER115c SPR6 sporulation-specific proteinYNL202w SPS19 sporulation-specific proteinYDR522c SPS2 sporulation-specific proteinYOR313c SPS4 sporulation-specific proteinYGR059w SPR3 sporulation-specific septinYHR139c SPS100 sporulation-specific wall maturation

proteinYNL204c SPS18 sporulation-specific zinc-finger protein

YBR078w strong similarity to sporulation-specificSps2p

YCL048w strong similarity to sporulation-specificSps2p

YDR055w strong similarity to Sps2pYOR075w UFE1 syntaxin (T-SNARE) of the ERYMR043w MCM1 transcription factor of the MADS box

familyYJR094c IME1 transcription factor required for

sporulationYNL330c RPD3 transcription modifier proteinYOL004w SIN3 transcription regulatory proteinYNL012w SPO1 transcriptional regulator involved in

sporulationYLL039c UBI4 ubiquitin YGL058w RAD6 ubiquitin-conjugating enzymeYDR177w UBC1 ubiquitin-conjugating enzymeYER125w RSP5 ubiquitin-protein ligaseYML115c VAN1 vanadate resistance protein

meiosis

YPR103w PRE2 26S proteasome subunitYGR253c PUP2 26S proteasome subunitYKL112w ABF1 ARS-binding factorYFL037w TUB2 β-tubulinYOR265w RBL2 β-tubulin binding proteinYPL204w HRR25 casein kinase I, ser/thr/tyr protein kinaseYBR136w ESR1 cell cycle checkpoint proteinYPL255w BBP1 cell division control proteinYDL220c CDC13 cell division control proteinYPL042c SSN3 cyclin-dependent ser/thr protein kinaseYOR368w RAD17 DNA damage checkpoint control proteinYMR224c MRE11 DNA repair and meiotic recombination

proteinYNL250w RAD50 DNA repair proteinYDR076w RAD55 DNA repair proteinYDR004w RAD57 DNA repair proteinYDR369c XRS2 DNA repair proteinYLR234w TOP3 DNA topoisomerase IIIYGL163c RAD54 DNA-dependent ATPase of the Snf2p

familyYNL025c SSN8 DNA-directed RNA polymerase II

holoenzyme and Kornberg’s mediator(SRB) subcomplex subunit, cyclin Chomolog

YKL017c DIP1 Dom34p Interacting ProteinYLR129w DIP2 Dom34p-interacting proteinYBR045c GIP1 Glc7-interacting proteinYPL240c HSP82 heat-shock proteinYJL146w IDS2 IME2-dependent signaling proteinYOR198c BFR1 maintenance of normal ploidyYHL022c SPO11 meiosis-specific proteinYER179w DMC1 meiosis-specific proteinYIL072w HOP1 meiosis-specific proteinYER180c ISC10 meiosis-specific proteinYER044c-a MEI4 meiosis-specific proteinYDL154w MSH5 meiosis-specific proteinYHR124w NDT80 meiosis-specific proteinYHR157w REC104 meiosis-specific proteinYLR263w RED1 meiosis-specific proteinYHR079c-a SAE3 meiosis-specific proteinYHR014w SPO13 meiosis-specific proteinYPL121c MEI5 meiotic proteinYBR057c MUM2 meiotic proteinYAL009w SPO7 meiotic proteinYNL210w MER1 meiotic recombination proteinYHR086w NAM8 meiotic recombination proteinYLR329w REC102 meiotic recombination proteinYJR021c REC107 meiotic recombination proteinYMR133w REC114 meiotic recombination proteinYGL175c SAE2 meiotic recombination proteinYHL027w RIM101 meiotic regulatory proteinYDR207c UME6 negative transcriptional regulatorYBL058w SHP1 potential regulatory subunit for Glc7pYMR076c PDS5 precocious dissociation of sister

chromatidsYDL017w CDC7 protein kinaseYIR026c YVH1 protein tyrosine phosphataseYOR208w PTP2 protein tyrosine phosphataseYBR073w RDH54 required for meiosisYER133w GLC7 ser/thr phosphoprotein phosphatase 1,


regulatory subunit YJL106w IME2 ser/thr protein kinaseYMR139w MDS1 ser/thr protein kinaseYOR351c MEK1 ser/thr protein kinaseYDR523c SPS1 ser/thr protein kinaseYNL307c MCK1 ser/thr/tyr protein kinaseYDL028c MPS1 ser/thr/tyr protein kinaseYNL001w DOM34 similarity to D. melanogaster pelota

proteinYFL003c MSH4 similarity to MSH proteinsYHR152w SPO12 sporulation proteinYHR153c SPO16 sporulation proteinYDR108w GSG1 sporulation-specific proteinYNL202w SPS19 sporulation-specific proteinYDR522c SPS2 sporulation-specific proteinYNL204c SPS18 sporulation-specific zinc-finger proteinYBR078w strong similarity to sporulation-specific

Sps2pYCL048w strong similarity to sporulation-specific

Sps2pYDR055w strong similarity to Sps2pYGR258c RAD2 structure-specific nuclease of the

nucleotide excision repairosomeYDR285w ZIP1 synaptonemal complex protein

YJR094c IME1 transcription factor required forsporulation

YGR044c RME1 zinc-finger transcription factor

DNA synthesis and replication

YKL112w ABF1 ARS-binding factorYFL009w CDC4 cell division control proteinYDR364c CDC40 cell division control proteinYLR274w CDC46 cell division control proteinYBR202w CDC47 cell division control proteinYJL194w CDC6 cell division control proteinYML102w CAC2 chromatin assembly complex, subunit YBR195c MSI1 chromatin assembly complex, subunit

p50YPR018w RLF2 chromatin assembly complex, subunit

p90YPR120c CLB5 cyclin, B-typeYGR109c CLB6 cyclin, B-typeYPL256c CLN2 cyclin, G1/S specificYBR160w CDC28 cyclin-dependent protein kinaseYER176w DNA dependent ATPase/DNA helicase BYHR164c DNA2 DNA helicaseYDL164c CDC9 DNA ligaseYJL173c RFA3 DNA replication factor A, 13K subunitYNL312w RFA2 DNA replication factor A, 36K subunitYAR007c RFA1 DNA replication factor A, 69K subunitYOL094c RFC4 DNA replication factor C, 37K subunitYNL290w RFC3 DNA replication factor C, 40K subunitYBR087w RFC5 DNA replication factor C, 40K subunit YJR068w RFC2 DNA replication factor C, 41K subunitYOR217w RFC1 DNA replication factor C, 95K subunitYJR006w HUS2 DNA replication proteinYOL006c TOP1 DNA topoisomerase IYNL088w TOP2 DNA topoisomerase II (ATP-hydrolysing)YNL102w CDC17 DNA-directed DNA polymerase α, 180K

subunitYIR008c PRI1 DNA-directed DNA polymerase α, 48K

subunit (DNA primase)YKL045w PRI2 DNA-directed DNA polymerase α, 58K

subunit (DNA primase)YPR135w POB1 DNA-directed DNA polymerase α-binding

proteinYDL102w CDC2 DNA-directed DNA polymerase δ,

catalytic 125K subunitYNL262w POL2 DNA-directed DNA polymerase ε, catalytic

subunit AYPR175w DPB2 DNA-directed DNA polymerase ε, subunit

BYBR278w DPB3 DNA-directed DNA polymerase ε, subunit

CYOR330c MIP1 DNA-directed DNA polymerase γ, catalytic

subunit, mitochondrialYPL167c REV3 DNA-directed DNA polymerase ζYFL036w RPO41 DNA-directed RNA polymerase,

mitochondrialYMR072w ABF2 high-mobility group proteinYJL090c DPB11 involved in DNA replication and S-phase

checkpointYDR068w DOS1 involved in genome stabilityYMR001c CDC5 involved in regulation of DNA replicationYPR019w CDC54 member of the Cdc46p/Mcm2p/Mcm3p

familyYBL023c MCM2 member of the Mcm2p,Mcm3p,Cdc46p

familyYML065w ORC1 origin recognition complex, 104K subunitYNL261w ORC5 origin recognition complex, 50K subunitYHR118c ORC6 origin recognition complex, 50K subunitYPR162c ORC4 origin recognition complex, 56K subunitYLL004w ORC3 origin recognition complex, 62K subunitYBR060c RRR1 origin recognition complex, 72K subunitYGR132c PHB1 prohibitin, antiproliferative proteinYBR088c POL30 proliferating cell nuclear antigen (PCNA)YDL017w CDC7 protein kinaseYFR028c CDC14 protein-tyrosine-phosphataseYDR052c DBF4 regulatory subunit for Cdc7p protein

kinaseYEL032w MCM3 replication initiation proteinYIL139c REV7 required for DNA damage-induced

mutagenesisYLR103c CDC45 required for minichromosome

maintenance and initiation ofchromosomal DNA replication

YIL150c DNA43 required for S-phase initiation orcompletion

YER070w RNR1 ribonucleoside-diphosphate reductase,large subunit

YJL026w RNR2 ribonucleoside-diphosphate reductase,small subunit

YIL066c RNR3 ribonucleotide reductase, repair inducibleYJL065c similarity to DNA-directed DNA

polymerase II subunit CYDR206w similarity to EST1 proteinYOR005c similarity to human mRNA for DNA ligase

IVYOL095c similarity to S. aureus DNA helicase

PCRAYGL201c similarity with rat intestinal DNA

replication proteinYKL113c RAD27 ssDNA endonuclease and

5’-3’exonucleaseYCR028c-a RIM1 ssDNA-binding protein, mitochondrialYGR231c strong similarity to prohibitinsYBL035c POL12 subunit of DNA polymerase α-primase

complexYLR233c EST1 telomere elongation proteinYCR077c (PAT1) topoisomerase II-associated proteinYOL115w TRF4 topoisomerase I-related protein


gazetteer

YLR182w SWI6 transcription factorYDR054c CDC34 ubiquitin-conjugating enzymeYGL058w RAD6 ubiquitin-conjugating enzyme

recombination and DNA repair

YGL127c SOH1 allows hpr1 null mutant to grow at 37ºC YBR136w ESR1 cell-cycle checkpoint proteinYER173w RAD24 cell-cycle checkpoint proteinYDR182w CDC1 cell-division control proteinYMR106c HDF2 component of DNA end-joining repair

pathwayYKL011c CCE1 cruciform-cutting endonuclease,

mitochondrialYER176w DNA-dependent ATPase/DNA helicase BYLR032w RAD5 DNA helicaseYMR190c SGS1 DNA helicaseYML061c PIF1 DNA helicase involved in mitochondrial

DNA repair and telomere lengthYDL164c CDC9 DNA ligaseYMR167w MLH1 DNA mismatch repair proteinYOL090w MSH2 DNA mismatch repair proteinYNL082w PMS1 DNA mismatch repair proteinYHR120w MSH1 DNA mismatch repair protein,

mitochondrialYCR014c POL4 DNA polymeraseYMR224c MRE11 DNA repair and meiotic recombination

proteinYJR035w RAD26 DNA repair and recombination proteinYEL019c MMS21 DNA repair proteinYML095c RAD10 DNA repair proteinYCR066w RAD18 DNA repair proteinYNL250w RAD50 DNA repair proteinYER095w RAD51 DNA repair proteinYDR076w RAD55 DNA repair proteinYDR004w RAD57 DNA repair proteinYDR369c XRS2 DNA repair proteinYAR007c RFA1 DNA replication factor A, 69K subunitYOL006c TOP1 DNA topoisomerase IYNL088w TOP2 DNA topoisomerase II (ATP-hydrolysing)YGL163c RAD54 DNA-dependent ATPase of the Snf2p

familyYFR023w PES4 DNA-directed DNA polymerase ε

suppressorYPL167c REV3 DNA-directed DNA polymerase ζYCR092c MSH3 DNA-repair proteinYKR056w RNC1 endo-exonucleaseYOR033c DHS1 exonuclease, interacting with Msh2pYLR288c MEC3 G2-specific checkpoint proteinYMR284w HDF1 high-affinity DNA-binding proteinYDR138w HPR1 hyperrecombination protein related to

Top1pYHL022c SPO11 meiosis-specific proteinYER179w DMC1 meiosis-specific proteinYIL072w HOP1 meiosis-specific proteinYHR157w REC104 meiosis-specific proteinYLR263w RED1 meiosis-specific proteinYPL121c MEI5 meiotic proteinYNL210w MER1 meiotic recombination proteinYHR086w NAM8 meiotic recombination proteinYLR329w REC102 meiotic recombination proteinYJR021c REC107 meiotic recombination proteinYGL175c SAE2 meiotic recombination proteinYBR114w RAD16 nucleotide excision repair proteinYGL025c PGD1 probable transcription factorYBR088c POL30 proliferating cell nuclear antigen (PCNA)YML032c RAD52 recombination and DNA repair proteinYDL059c RAD59 recombination and DNA repair proteinYLR383w RHC18 recombination repair proteinYBR073w RDH54 required for meiosisYIL066c RNR3 ribonucleotide reductase, repair inducibleYMR228w MTF1 RNA polymerase specific factor,

mitochondrialYOR351c MEK1 ser/thr protein kinaseYPL164c similarity to mismatch repair protein

Mlh1pYOR077w RTS2 similarity to mouse KIN17 proteinYFL003c MSH4 similarity to MSH proteinsYDR097c MSH6 similarity to MSH proteinsYHR031c similarity to Pif1pYGL043w DST1 TFIIS (transcription elongation factor)YCR077c (PAT1) topoisomerase II-associated proteinYGR063c SPT4 transcription initiation proteinYGR116w SPT6 transcription initiation proteinYML021c UNG1 uracil-DNA glycosylase

cell-cycle control and mitosis

YFR052w NIN1 26S proteasome regulatory subunitYPR103w PRE2 26S proteasome subunitYGL048c SUG1 26S proteasome subunitYKL145w YTA3 26S proteasome subunitYJL005w CYR1 adenylate cyclaseYPL239w YAR1 ankyrin repeat-containing proteinYHR101c BIG1 big cells phenotypeYHR208w TWT1 branched-chain amino-acid

aminotransferase, mitochondrialYFL037w TUB2 β-tubulinYBR200w BEM1 bud emergence mediatorYBR109c CMD1 calmodulinYOR061w CKA2 casein kinase II α‘ subunitYIL035c CKA1 casein kinase II, catalytic α subunitYER123w YCK3 casein kinase, isoform 3YLR178c TFS1 cdc25-dependent nutrient- and ammonia-

response cell-cycle regulatorYGR049w SCM4 cdc4 suppressorYFL029c CAK1 cdk-activating protein kinaseYMR055c BUB2 cell-cycle arrest protein

YOR026w BUB3 cell-cycle arrest proteinYPL178w SAE1 cell-cycle block in meiotic prophaseYBR136w ESR1 cell-cycle checkpoint proteinYPR111w DBF20 cell-cycle protein kinase related to Dbf2pYDR113c PDS1 cell-cycle regulatorYBR215w HPC2 cell-cycle regulatory proteinYOR373w NUD1 cell-cycle regulatory proteinYPL255w BBP1 cell division control proteinYDR182w CDC1 cell division control proteinYCR002c CDC10 cell division control proteinYDL220c CDC13 cell division control proteinYGL116w CDC20 cell division control proteinYLR314c CDC3 cell division control proteinYDR168w CDC37 cell division control proteinYFL009w CDC4 cell division control proteinYDR364c CDC40 cell division control proteinYLR274w CDC46 cell division control proteinYBR202w CDC47 cell division control proteinYJL194w CDC6 cell division control proteinYNL188w KAR1 cell division control proteinYDL226c GCS1 cell proliferation zinc-finger proteinYNL327w EGT2 cell-cycle regulation proteinYHR129c ACT5 centractinYLR175w CBF5 centromere/microtubule binding proteinYDR254w CHL4 chromosome segregation proteinYOR349w CIN1 chromosome segregation proteinYFL008w SMC1 chromosome segregation proteinYFR031c SMC2 chromosome segregation proteinYMR028w TAP42 component of the Tor signalling pathwayYIL106w MOB1 conditional mutants arrest in late mitosisYDL132w CDC53 controls G1/S transitionYPR120c CLB5 cyclin, B-typeYGR109c CLB6 cyclin, B-typeYMR199w CLN1 cyclin, G1/S specificYPL256c CLN2 cyclin, G1/S specificYAL040c CLN3 cyclin, G1/S specificYNL289w PCL1 cyclin, G1/S specificYDL127w PCL2 cyclin, G1/S specificYGR108w CLB1 cyclin, G2/M-specificYPR119w CLB2 cyclin, G2/M-specificYDL155w CLB3 cyclin, G2/M-specificYLR210w CLB4 cyclin, G2/M-specificYBR135w CKS1 cyclin-dependent kinase regulatory

subunitYBR160w CDC28 cyclin-dependent protein kinaseYPL031c PHO85 cyclin-dependent protein kinaseYDL108w KIN28 cyclin-dependent ser/thr protein kinaseYGL215w CLG1 cyclin-like proteinYOR368w RAD17 DNA damage checkpoint control proteinYDR217c RAD9 DNA repair checkpoint proteinYOR217w RFC1 DNA replication factor C, 95K subunitYLR234w TOP3 DNA topoisomerase IIIYKL017c DIP1 Dom34p-interacting proteinYLR129w DIP2 Dom34p-interacting proteinYNL053w MSG5 dual-specifity protein phosphataseYKR054c DYN1 dynein heavy chain, cytosolicYDR172w SUP35 eukaryotic peptide chain release factor

GTP-binding subunitYNL292w EXM1 exit from mitosisYDL087c EXM2 exit from mitosisYJL157c FAR1 factor arrest proteinYLR212c TUB4 γ tubulinYLR288c MEC3 G2-specific checkpoint proteinYAL024c LTE1 GDP/GTP exchange factorYLL016w SDC25 GDP/GTP exchange factorYAL041w CDC24 GDP/GTP exchange factor for Cdc42pYLR310c CDC25 GDP/GTP exchange factor for Ras1p and

Ras2pYGL207w SPT16 general chromatin factorYGL155w CDC43 geranylgeranyltransferase type I β subunitYER155c BEM2 GTPase-activating proteinYMR138w CIN4 GTP-binding proteinYNL098c RAS2 GTP-binding proteinYLR229c CDC42 GTP-binding protein of RAS superfamilyYML064c TEM1 GTP-binding protein of the RAS

superfamilyYNL007c SIS1 heat-shock proteinYBR133c HSL7 histone synthetic lethalityYJL080c SCP160 histone-like proteinYOL076w DEC1 interacts genetically with CIN8YOR156c NFI1 interacts with Cdc12p in 2-hybrid assayYNR010w CSE2 interacts with centromeric element CDEIIYML104c MDM1 intermediate filament proteinYKR072c SIS2 involved in cell cycle-specific gene

expressionYKR063c LAS1 involved in cell morphogenesis,

cytoskeletal regulation and bud formationYPL241c CIN2 involved in chromosome segregationYPL018w CTF19 involved in chromosome segregationYJL090c DPB11 involved in DNA replication and S-phase

checkpointYMR273c ZDS1 involved in negative regulation of cell

polarityYMR052w FAR3 involved in pheromone-mediated cell

cycle arrestYMR052w FAR3 involved in pheromone-mediated cell

cycle arrestYMR001c CDC5 involved in regulation of DNA replicationYMR127c SAS2 involved in silencing at HMRYKR042w UTH1 involved in the aging processYDR293c SSD1 involved in the tolerance to high


YNL189w SRP1 karyopherin-α or importinYEL061c CIN8 kinesin-related proteinYPR141c KAR3 kinesin-related proteinYBL063w KIP1 kinesin-related proteinYJR060w CBF1 kinetochore protein

YGR140w CBF2 kinetochore protein complex CBF3, 110Ksubunit

YMR094w CTF13 kinetochore protein complex CBF3, 58Ksubunit

YMR168c CEP3 kinetochore protein complex CBF3, 71Ksubunit

YDR328c SKP1 kinetochore protein complex CBF3,subunit D

YOR198c BFR1 maintenance of normal ploidyYLR332w MID2 mating process proteinYER179w DMC1 meiosis-specific proteinYHR079c-a SAE3 meiosis-specific proteinYPR019w CDC54 member of the Cdc46p/Mcm2p/Mcm3p

familyYDL126c CDC48 microsomal protein of

CDC48/PAS1/SEC18 family of ATPasesYOR058c ASE1 microtubule-associated proteinYNL064c YDJ1 mitochondrial and ER import proteinYGR029w ERV1 mitochondrial biogenesis and regulation

of cell cycleYBL016w FUS3 mitogen-activated protein kinase (MAP

kinase)YMR294w JNM1 mitosis protein, involved in nuclear

migrationYMR036c MIH1 M-phase inducing protein tyrosine

phosphataseYGL178w MPT5 multicopy suppressor of pop2YML109w ZDS2 multicopy suppressor of sin4YGL173c KEM1 multifunctional nucleaseYDR207c UME6 negative transcriptional regulatorYBL020w RFT1 nuclear division proteinYNL299w TRF5 nuclear division proteinYML031w NDC1 nuclear envelope proteinYJR112w NNF1 nuclear envelope proteinYCL029c BIK1 nuclear fusion proteinYJL034w KAR2 nuclear fusion proteinYDR150w NUM1 nuclear migration proteinYAL025c MAK16 nuclear viral propagation proteinYKR048c NAP1 nucleosome assembly protein IYLR079w SIC1 p40 inhibitor of Cdc28p-Clb protein kinase

complexYJR066w TOR1 phosphatidylinositol 3-kinaseYKL203c TOR2 phosphatidylinositol 3-kinaseYLR305c STT4 phosphatidylinositol-4-kinaseYCL004w PEL1 phosphatidylserine synthaseYBL058w SHP1 potential regulatory subunit for Glc7pYGL238w CSE1 probable kinetochore proteinYGR132c PHB1 prohibitin, antiproliferative proteinYDL017w CDC7 protein kinaseYOR149c SMP3 protein kinase C pathway proteinYPL140c MKK2 protein kinase of the MAP kinase kinase

(MEK) familyYAR019c CDC15 protein kinase of the MAP kinase kinase

kinase familyYHR013c ARD1 protein N-acetyltransferase subunitYPL008w CHL1 protein of the DEAH box familyYDL047w SIT4 protein ser/thr phosphataseYDL134c PPH21 protein ser/thr phosphatase PP2A-1YDL188c PPH22 protein ser/thr phosphatase PP2A-2YBR267w PPS1 protein tyrosine phosphataseYFR028c CDC14 protein-tyrosine-phosphataseYOL021c DIS3 Ran binding proteinYDR137w RGP1 reduced growth phenotype proteinYDR052c DBF4 regulatory subunit for Cdc7p protein

kinaseYKL193c SDS22 regulatory subunit for the mitotic function

of type I protein phosphataseYMR078c CHL12 required for accurate chromosome

transmission in mitosis and maintenanceof normal telomere length

YOL145c CTR9 required for G1 cyclin expressionYLR103c CDC45 required for minichromosome

maintenance and initiation ofchromosomal DNA replication

YKL089w MIF2 required for normal chromosomesegregation and spindle integrity

YGR098c ESP1 required for normal spindle structureYIL150c DNA43 required for S-phase initiation or

completionYJL074c SMC3 required for structural maintenance of

chromosomesYGR078c PAC10 required in the absence of Cin8pYDR488c PAC11 required in the absence of Cin8pYLR075w GRC5 ribosomal proteinYJR076c CDC11 septinYHR107c CDC12 septinYAL016w TPD3 ser/thr phosphatase 2A, regulatory

subunit AYER133w GLC7 ser/thr phosphoprotein phosphatase 1,


regulatory subunit YGR188c BUB1 ser/thr protein kinaseYKL048c ELM1 ser/thr protein kinaseYJL106w IME2 ser/thr protein kinaseYPL209c IPL1 ser/thr protein kinaseYOR231w MKK1 ser/thr protein kinaseYBL105c PKC1 ser/thr protein kinaseYPR161c SGV1 ser/thr protein kinaseYJL141c YAK1 ser/thr protein kinaseYMR104c YPK2 ser/thr protein kinaseYHR030c SLT2 ser/thr protein kinase of MAP kinase


kinase C pathwayYGR092w DBF2 ser/thr protein kinase related to Dbf20p


gazetteer

YKL101w HSL1 ser/thr protein kinase that interactsgenetically with histone mutations

YHR102w NRK1 ser/thr protein kinase that interacts withCdc31p

YNL307c MCK1 ser/thr/tyr protein kinaseYDL028c MPS1 ser/thr/tyr protein kinaseYPL153c SPK1 ser/thr/tyr protein kinaseYJL187c SWE1 ser/tyr dual-specifity protein kinaseYGL003c similarity to C. elegans CDC20 protein

and human p55CDCYDL225w similarity to Cdc11p, Cdc3p and human

CDC10 proteinYDL179w similarity to cyclin G1 homologue HCS26YNL001w DOM34 similarity to D. melanogaster pelota

proteinYNL246w similarity to D. melanogaster SET proteinYAR003w FUN16 similarity to human RB protein binding

proteinYKL179c similarity to Nuf1pYDL125c YHI1 similarity to protein kinase C inhibitor-IYMR262w similarity to S. pombe scn1 proteinYLR356w similarity to SCM4 proteinYIL095w PRK1 similarity to ser/thr protein kinaseYLR179c similarity to Tfs1p and Nsp1pYOL080c similarity to X. laevis XPMC2 proteinYFR040w SAP155 Sit4p-associated proteinYKR028w SAP190 Sit4p-associated proteinYGL229c SAP4 Sit4p-associated proteinYJL098w SAP185 Sit4p-associating proteinYGL086w MAD1 spindle assembly checkpoint proteinYMR198w CIK1 spindle pole body associated proteinYDR356w NUF1 spindle pole body componentYKL042w SPC42 spindle pole body componentYNL126w SPC98 spindle pole body componentYOR257w CDC31 spindle pole body component, centrinYOL069w NUF2 spindle pole body proteinYJL030w MAD2 spindle-assembly checkpoint proteinYJL013c MAD3 spindle-assembly checkpoint proteinYGL106w strong similarity to calmodulinsYHR205w SCH9 strong similarity to cAMP-dependent

protein kinaseYER066w strong similarity to cell division control

protein Cdc4pYLR117c strong similarity to D. melanogaster

putative cell-cycle control protein crnYIR012w strong similarity to Dbf8pYBR238c strong similarity to general chromatin

factor Spt16pYKL049c CSE4 strong similarity to histone H3YGR231c strong similarity to prohibitinsYLR215c strong similarity to rat cell cycle

progression related D123 proteinYKL161c strong similarity to ser/thr-specific protein

kinase Slt2pYNL172w APC1 subunit of anaphase-promoting complex

(cyclosome)YKL022c CDC16 subunit of anaphase-promoting complex

(cyclosome)YHR166c CDC23 subunit of anaphase-promoting complex

(cyclosome)YFR036w CDC26 subunit of anaphase-promoting complex

(cyclosome)YBL084c CDC27 subunit of anaphase-promoting complex

(cyclosome)YOR213c subunit of the RSC complexYCR052w RSC6 subunit of the RSC complexYFR037c RSC8 subunit of the RSC complexYLR321c SFH1 subunit of the RSC complexYIL126w STH1 subunit of the RSC complexYJR091c JSN1 suppresses the high-temperature lethality

of tub2-150YIL031w SMT4 suppressor of mif2 temperature-sensitive

mutationYDR285w ZIP1 synaptonemal complex proteinYPL129w ANC1 TFIIF subunit (transcription initiation

factor), 30KYPR025c CCL1 TFIIH subunit (transcription initiation

factor), cyclin C component YLR043c TRX1 thioredoxin IYGR209c TRX2 thioredoxin IIYOL115w TRF4 topoisomerase I-related proteinYDL165w CDC36 transcription factorYER111c SWI4 transcription factorYLR182w SWI6 transcription factorYGL181w GTS1 transcription factor of the

Gcs1p/Glo3p/Sps18p familyYMR043w MCM1 transcription factor of the MADS box

familyYHR206w SKN7 transcription factor with similarity to Hsf1pYDL056w MBP1 transcription factor, subunit of the MBF

factorYOR028c CIN5 transcriptional activatorYNL012w SPO1 transcriptional regulator involved in

sporulationYOR361c PRT1 translation initiation factor eIF3 subunitYHR165c PRP8 U5 snRNP protein, pre-mRNA splicing

factorYDR054c CDC34 ubiquitin-conjugating enzymeYDL064w UBC9 ubiquitin-conjugating enzymeYMR276w DSK2 ubiquitin-like proteinYML115c VAN1 vanadate resistance proteinYHR071w weak similarity to cyclin G1 homolog

HCS26 proteinYER122c GLO3 zinc-finger proteinYLR403w SFP1 zinc-finger proteinYGR044c RME1 zinc-finger transcription factor

cytokinesis

YDL029w ACT2 actin-like proteinYPL255w BBP1 cell division control proteinYCR002c CDC10 cell division control proteinYLR314c CDC3 cell division control proteinYNL327w EGT2 cell-cycle regulation proteinYNL192w CHS1 chitin synthase IYLR286c CTS1 endochitinaseYOR156c NFI1 interacts with Cdc12p in 2-hybrid assayYNL225c involved in cytokinesisYLR131c ACE2 metallothionein expression activatorYAL029c MYO4 myosin heavy chain, unconventional

(class V) isoformYHR023w MYO1 myosin-1 isoform (type II myosin) heavy

chainYCR057c PWP2 periodic tryptophan proteinYNL267w PIK1 phosphatidylinositol 4-kinaseYJR076c CDC11 septinYHR107c CDC12 septinYGL190c CDC55 ser/thr phosphatase 2A regulatory


subunit AYNL298w CLA4 ser/thr protein kinaseYDL225w similarity to Cdc11p, Cdc3p and human

CDC10 proteinYMR197c similarity to Nuf1p

other cell-growth, cell-division and DNA-synthesis activities

YLR248w RCK2 Ca2+/calmodulin-dependent ser/thrprotein kinase

YOR101w RAS1 GTP-binding proteinYNL098c RAS2 GTP-binding proteinYBR138c HDR1 high-dosage reductional segregation

defectiveYHL003c LAG1 longevity-assurance proteinYDL003w MCD1 mitotic chromosome determinantYGL091c NBP35 nucleotide-binding proteinYOL110w SHR5 RAS suppressorYGL158w RCK1 ser/thr protein kinaseYKL189w similarity to mouse MO25 gene

TranscriptionrRNA synthesis

YJR063w RPA12 DNA-directed RNA polymerase I, 13.7KYPR010c RPA135 DNA-directed RNA polymerase I, 135K

subunitYOR341w RPA190 DNA-directed RNA polymerase I, 190K

α subunitYOR340c RPA43 DNA-directed RNA polymerase I, 36K

subunitYNL248c RPA49 DNA-directed RNA polymerase I, 49K

α subunitYDR156w RPA14 DNA-directed RNA polymerase I, A14

subunitYOR224c RPB8 DNA-directed RNA polymerase I, II, III 16K

subunitYPR187w RPO26 DNA-directed RNA polymerase I, II, III 18K

subunitYBR154c RPB5 DNA-directed RNA polymerase I, II, III 25K

subunitYHR143w-a RPC10 DNA-directed RNA polymerase I, II, III 7.7K

subunitYOR210w RPB10 DNA-directed RNA polymerase I, II, III

8.3K subunitYPR110c RPC40 DNA-directed RNA polymerase I, III 40K

subunitYNL113w RPC19 DNA-directed RNA polymerase I, III, 16K

subunitYOR207c RPC128 DNA-directed RNA polymerase III, 130K

subunitYOR116c RPO31 DNA-directed RNA polymerase III, 160K

subunitYKL144c RPC25 DNA-directed RNA polymerase III, 25K

subunitYNL151c RPC31 DNA-directed RNA polymerase III, 31K

subunitYNR003c RPC34 DNA-directed RNA polymerase III, 34K

subunitYDL150w RPC53 DNA-directed RNA polymerase III, 47K

subunitYPR190c RPC82 DNA-directed RNA polymerase III, 82K

subunitYLR039c RIC1 involved in transcription of ribosomal

proteins and ribosomal RNAYKL125w RRN3 RNA polymerase I specific transcription

factorYBL025w RRN10 RNA polymerase I specific transcription

initiation factorYML043c RRN11 RNA polymerase I specific transcription

initiation factorYLR141w RRN5 RNA polymerase I specific transcription

initiation factorYBL014c RRN6 RNA polymerase I specific transcription

initiation factorYJL025w RRN7 RNA polymerase I specific transcription

initiation factorYMR270c RRN9 RNA polymerase I specific transcription

initiation factorYER148w SPT15 TFIID and TFIIIB subunit

YPR186c TFC2 TFIIIA subunit (transcription initiationfactor)

YGR246c BRF1 TFIIIB subunit, 70KYNL039w TFC5 TFIIIB subunit, 90KYGR047c TFC4 TFIIIC subunit (transcription initiation

factor), 131KYAL001c TFC3 TFIIIC subunit (transcription initiation

factor), 138KYBR123c TFC1 TFIIIC subunit (transcription initiation

factor), 95KYBR049c REB1 transcription factor

rRNA processing

YOR048c RAT1 5’-3’ exoribonucleaseYBR142w MAK5 ATP-dependent RNA helicaseYNL112w DBP2 ATP-dependent RNA helicase of DEAD

box familyYFL002c SPB4 ATP-dependent RNA helicase of DEAH

box familyYPL029w SUV3 ATP-dependent RNA helicase,

mitochondrialYJL033w HCA4 can suppress the U14 snoRNA rRNA

processing functionYMR239c RNT1 double-stranded ribonucleaseYDL014w NOP1 fibrillarinYGL097w SRM1 GDP/GTP exchange factor for

Gsp1p/Gsp2pYMR235c RNA1 GTPase-activating proteinYLL011w SOF1 involved in 18S pre-rRNA productionYGR158c MTR3 involved in mRNA transportYGL173c KEM1 multifunctional nucleaseYGR159c NSR1 nuclear localization sequence binding

proteinYPL043w NOP4 nucleolar proteinYDR432w NPL3 nucleolar proteinYCR018c SRD1 nucleolar proteinYHR089c GAR1 nucleolar rRNA processing proteinYLR223c IFH1 pre-rRNA processing machinery control

proteinYMR229c RRP5 processing of pre-ribosomal RNAYNL221c POP1 protein component of ribonuclease P and

ribonuclease MRPYHR065c RRP3 required for maturation of the 35S primary

transcriptYLL008w DRS1 RNA helicase of the DEAD box familyYPL266w DIM1 rRNA (adenine-N6,N6-)-

dimethyltransferaseYOR201c PET56 rRNA (guanosine-2’-O-)-methyltransferaseYPL021w SRD2 similarity to Srd1pYHL034c SBP1 single-strand nucleic acid binding proteinYLR059c YNT20 suppressor of rna12 yme2

other rRNA-transcription activities

YNL216w RAP1 DNA-binding protein with repressor andactivator activity

YMR302c PRP12 involved in early maturation of pre-rRNA

tRNA synthesis

YGL019w CKB1 casein kinase II, β subunitYOR224c RPB8 DNA-directed RNA polymerase I, II, III 16K





8.3K subunitYPR110c RPC40 DNA-directed RNA polymerase I, III 40K

subunitYNL113w RPC19 DNA-directed RNA polymerase I, III, 16K

subunitYOR207c RPC128 DNA-directed RNA polymerase III, 130K

subunitYOR116c RPO31 DNA-directed RNA polymerase III, 160K

subunitYKL144c RPC25 DNA-directed RNA polymerase III, 25K

subunitYNL151c RPC31 DNA-directed RNA polymerase III, 31K

subunitYNR003c RPC34 DNA-directed RNA polymerase III, 34K

subunitYDL150w RPC53 DNA-directed RNA polymerase III, 47K

subunitYPR190c RPC82 DNA-directed RNA polymerase III, 82K

subunitYER148w SPT15 TFIID and TFIIIB subunitYPR186c TFC2 TFIIIA subunit (transcription initiation

factor)YGR246c BRF1 TFIIIB subunit, 70KYNL039w TFC5 TFIIIB subunit, 90KYGR047c TFC4 TFIIIC subunit (transcription initiation

factor), 131KYAL001c TFC3 TFIIIC subunit (transcription initiation

factor), 138KYBR123c TFC1 TFIIIC subunit (transcription initiation

factor), 95K

tRNA processing

YIL075c SEN3 26S proteasome regulatory subunitYGL097w SRM1 GDP/GTP exchange factor for

Gsp1p/Gsp2pYMR235c RNA1 GTPase activating protein


gazetteer

YHR006w STP2 involved in pre-tRNA splicingYLR375w STP3 involved in pre-tRNA splicing and in

uptake of branched-chain amino acidsYDL048c STP4 involved in pre-tRNA splicing and in

uptake of branched-chain amino acidsYCL017c NFS1 involved in tRNA processing and

mitochondrial metabolsimYNR034w SOL1 multicopy suppressor of los1-1YCR073w-a SOL2 multicopy suppressor of los1-1YMR047c NUP116 nuclear pore proteinYGL092w NUP145 nuclear pore proteinYJR042w NUP85 nuclear pore proteinYLR430w SEN1 positive effector of tRNA-splicing

endonucleaseYAL043c PTA1 pre-tRNA processing proteinYKL205w LOS1 pre-tRNA splicing proteinYDR463w STP1 pre-tRNA splicing proteinYNL221c POP1 protein component of ribonuclease P and

ribonuclease MRPYML091c RPM2 ribonuclease P, mitochondrialYFR004w MPR1 strong similarity to S. pombe pad1 proteinYGR248w SOL4 strong similarity to Sol3pYJL087c TRL1 tRNA ligaseYLR105c SEN2 tRNA splicing endonuclease β subunitYHR163w SOL3 weak multicopy suppressor of los1-1

tRNA modification

YGR204w ADE3 C1-tetrahydrofolate synthase, cytoplasmicYMR283c RIT1 initiator tRNA phosphoribosyl-transferaseYDR120c TRM1 N2,N2-dimethylguanine tRNA

methyltransferaseYGL105w G4P1 protein with specific affinity for G4

quadruplex nucleic acidsYPL212c PUS1 pseudouridine synthase 1YGL063w PUS2 pseudouridine synthase 2YFR010w similarity to C. elegans tRNA-guanine

transglycosylaseYBL013w similarity to methionyl-tRNA

formyltransferaseYOR274w MOD5 tRNA isopentenyltransferaseYER168c CCA1 tRNA nucleotidyltransferase

other tRNA-transcription activities

YOR061w CKA2 casein kinase II α‘ subunitYOR039w CKB2 casein kinase II β‘ subunitYJL041w NSP1 nuclear pore protein

mRNA synthesis

ggeenneerraall ttrraannssccrriippttiioonn aaccttiivviittiieessYDL108w KIN28 cyclin-dependent ser/thr protein kinaseYIL143c SSL2 DNA helicaseYER171w RAD3 DNA helicase/ATPaseYOR224c RPB8 DNA-directed RNA polymerase I, II, III 16K





8.3K subunitYOL051w GAL11 DNA-directed RNA polymerase II


YDR443c SCA1 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit

YHR041c SRB2 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit

YER022w SRB4 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit

YGR104c SRB5 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit

YDR308c SRB7 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit

YCR081w SRB8 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit

YNL025c SSN8 DNA-directed RNA polymerase IIholoenzyme and Kornberg’s mediator(SRB) subcomplex subunit, cyclin Chomologue



YOL005c RPB11 DNA-directed RNA polymerase II, 13.6Ksubunit

YGL070c RPB9 DNA-directed RNA polymerase II, 14.2Ksubunit

YOR151c RPB2 DNA-directed RNA polymerase II, 140Ksubunit

YDR404c RPB7 DNA-directed RNA polymerase II, 19Ksubunit

YDL140c RPO21 DNA-directed RNA polymerase II, 215Ksubunit

YJL140w RPB4 DNA-directed RNA polymerase II, 32Ksubunit

YFL036w RPO41 DNA-directed RNA polymerase,mitochondrial

YIL021w RPB3 DNA-directed RNA-polymerase II, 45KYIL128w MMS19 involved in repair and RNA polymerase

transcriptionYMR228w MTF1 RNA polymerase specific factor,

mitochondrialYPR056w similarity to human transcription factor

BTF2/TFIIH subunit p34YPL046c strong similarity to human DNA-directed

RNA polymerase II elongation factor SIII,p15

YDR045c strong similarity to S. acidocaldariustranscription elongation factor tfs

YKL058w TOA2 TFIIA subunit (transcription initiationfactor), 13.5K

YOR194c TOA1 TFIIA subunit (transcription initiationfactor), 32K

YPR086w SUA7 TFIIB subunit (transcription initiationfactor), factor E

YER148w SPT15 TFIID and TFIIIB subunitYGR274c TAF145 TFIID subunit (TBP-associated factor),

145KYMR236w TAF17 TFIID subunit (TBP-associated factor), 17K YML098w TAF19 TFIID subunit (TBP-associated factor), 19KYDR167w TAF23 TFIID subunit (TBP-associated factor), 23KYML015c TAF40 TFIID subunit (TBP-associated factor), 40KYGL112c TAF60 TFIID subunit (TBP-associated factor), 60KYDR145w TAF61 TFIID subunit (TBP-associated factor), 61KYMR227c TAF67 TFIID subunit (TBP-associated factor), 67KYBR198c TAF90 TFIID subunit (TBP-associated factor), 90KYKR062w TFA2 TFIIE subunit (transcription initiation

factor), 43K YKL028w TFA1 TFIIE subunit (transcription initiation

factor), 66K YGR186w TFG1 TFIIF subunit (transcription initiation

factor), 105K YPL129w ANC1 TFIIF subunit (transcription initiation

factor), 30KYGR005c TFG2 TFIIF subunit (transcription initiation

factor), 54K YDR311w TFB1 TFIIH subunit (transcription initiation


factor), cyclin C component YLR005w SSL1 TFIIH subunit (transcription initiation

factor), factor BYPL122c TFB2 TFIIH subunit (transcription/repair factor)YDR460w TFB3 TFIIH subunit (transcription/repair factor)YGL043w DST1 TFIIS (transcription elongation factor)YGR063c SPT4 transcription initiation proteinYML010w SPT5 transcription initiation proteinYGR116w SPT6 transcription initiation protein

ttrraannssccrriippttiioonnaall ccoonnttrroollYOR259c CRL13 26S proteasome subunitYJL115w ASF1 anti-silencing proteinYDL197c ASF2 anti-silencing proteinYDR173c ARG82 arginine metabolism transcription factorYKL112w ABF1 ARS-binding factorYDR123c INO2 basic helix-loop-helix (BHLH) transcription

factorYOL108c INO4 basic helix-loop-helix transcription factorYOL067c RTG1 basic helix-loop-helix transcription factorYOR344c TYE7 basic helix-loop-helix transcription factorYBL103c RTG3 bHLH/zip transcription factorYHL009c bZip DNA binding proteinYGL209w MIG2 C2H2 zinc-finger proteinYKL190w CNB1 calcineurin B, regulatory subunitYML112w CTK3 carboxy terminal domain (CTD) kinase,

γ subunitYJL006c CTK2 carboxy-terminal domain (CTD) kinase ,

β subunitYKL139w CTK1 carboxy-terminal domain (CTD) kinase,

α subunitYIL035c CKA1 casein kinase II, catalytic α subunitYGL237c HAP2 CCAAT-binding factor subunitYBL021c HAP3 CCAAT-binding factor subunitYKL109w HAP4 CCAAT-binding factor subunitYOR358w HAP5 CCAAT-binding factor subunitYJR122w CAF17 CCR4-associated factorYKR036c CAF4 CCR4-associated factorYBR215w HPC2 cell-cycle regulatory proteinYDL220c CDC13 cell division control proteinYDR073w SNF11 component of SWI/SNF transcription

activator complexYNR023w SNF12 component of SWI/SNF transcription




activator complexYCR042c TSM1 component of TAF(II) complexYPL177c CUP9 copper homeostasis proteinYGL166w CUP2 copper-dependent transcription factorYNL167c SKO1 cre-binding bzip proteinYPL042c SSN3 cyclin-dependent ser/thr protein kinaseYLR176c RFX1 DNA binding proteinYDR217c RAD9 DNA repair checkpoint proteinYNL216w RAP1 DNA-binding protein with repressor and

activator activityYLR418c CDC73 DNA-directed RNA polymerase II

accessory proteinYBR279w PAF1 DNA-directed RNA polymerase II

regulatorYGL208w SIP2 dominant suppressor of some ts

mutations rpo21 and prp4

YOR047c STD1 dosage-dependent modulator of glucoserepression

YER159c NCB1 functional homologue of human NC2αYDR397c YNC2β functional homologue of human

NC2β/Dr1YPL037c EGD1 GAL4 DNA-binding enhancer proteinYJL110c GZF3 GATA zinc-finger protein 3YIL038c NOT3 general negative regulator of transcription,

subunit 3YBR112c CYC8 general repressor of transcriptionYCR084c TUP1 general transcription repressorYDR176w NGG1 general transcriptional adaptor or co-

activatorYBR045c GIP1 Glc7p-interacting proteinYNL236w SIN4 global regulator proteinYHL025w SNF6 global transcription activatorYER027c GAL83 glucose repression proteinYNL199c GCR2 glycolytic genes transcriptional activatorYGL073w HSF1 heat shock transcription factorYPR065w ROX1 heme-dependent transcriptional repressor

of hypoxic genesYDR006c SOK1 high copy suppressor of a cyclic AMP-

dependent protein kinase mutantYMR070w HMS1 high-copy suppressor of mot1 spt3

synthetic lethalityYGR252w GCN5 histone acetyltransferaseYDR225w HTA1 histone H2AYBL003c HTA2 histone H2A.2YDR224c HTB1 histone H2BYBL002w HTB2 histone H2B.2YBR010w HHT1 histone H3YNL031c HHT2 histone H3YBR009c HHF1 histone H4YNL030w HHF2 histone H4YBL008w HIR1 histone transcription regulatorYOR038c HIR2 histone transcription regulatorYER161c SPT2 HMG-like chromatin proteinYDL106c GRF10 homeodomain proteinYDR138w HPR1 hyperrecombination protein related to

Top1pYJL089w SIP4 interacts with SNF1 protein kinaseYKL032c IXR1 intrastrand crosslink recognition protein

and transcription factorYBR081c SPT7 involved in alteration of transcription start

site selectionYKR072c SIS2 involved in cell cycle-specific gene

expressionYNL251c NRD1 involved in regulation of nuclear pre-

mRNA abundanceYIL046w MET30 involved in regulation of sulphur

assimilation genesYDL153c SAS10 involved in silencingYMR127c SAS2 involved in silencing at HMRYGR097w ASK10 involved in Skn7p-dependent transcriptionYLR039c RIC1 involved in transcription of ribosomal

proteins and ribosomal RNAYGL071w RCS1 iron-regulated transcriptional repressorYJR060w CBF1 kinetochore proteinYDR159w SAC3 leucine permease transcriptional regulatorYGR100w MIC1 Mac1p interacting proteinYBR297w MAL33 maltose fermentation regulatory proteinYGR288w MAL13 maltose pathway regulatory proteinYCR040w MATα1 mating type regulatory protein (expressed

copy at MAT locus)YCR039c MATα2 mating type regulatory protein (expressed

copy at MAT locus)YCL067c α2 mating type regulatory protein (silenced

copy at HML locus)YHL027w RIM101 meiotic regulatory proteinYLR216c CPR6 member of the cyclophilin familyYJR032w CPR7 member of the cyclophilin familyYLR136c TIS11 member of the inducible ccch zinc-finger

familyYOL148c SPT20 member of the TBP class of SPT proteins

that alter transcription site selectionYMR021c MAC1 metal binding activatorYLR131c ACE2 metallothionein expression activatorYBR026c (MRF1) mitochondrial respiratory function proteinYML051w GAL80 negative regulator for expression of

galactose-induced genesYGL151w NUT1 negative regulator of HO endonucleaseYPR168w NUT2 negative regulator of HO endonucleaseYKL185w ASH1 negative regulator of HO expressionYHL020c OPI1 negative regulator of phospholipid

biosynthesis pathwayYDR464w SPP41 negative regulator of PRP3 and PRP4

gene expressionYNL076w MKS1 negative regulator of RAS-cAMP pathwayYDR207c UME6 negative transcriptional regulatorYGL221c NIF3 Ngg1p-interacting factor 3YGL115w SNF4 nuclear regulatory proteinYCR093w CDC39 nuclear transmembrane proteinYML065w ORC1 origin recognition complex, 104K subunitYNL261w ORC5 origin recognition complex, 50K subunitYHR118c ORC6 origin recognition complex, 50K subunitYPR162c ORC4 origin recognition complex, 56K subunitYLL004w ORC3 origin recognition complex, 62K subunitYBR060c RRR1 origin recognition complex, 72K subunitYAL051w OAF1 peroxisome proliferating transcription

factorYOR363c PIP2 peroxisome proliferating transcription

factorYBL005w PDR3 pleiotropic drug resistance regulatory

proteinYKL015w PUT3 positive activator of the proline utilization

pathwayYGL192w IME4 positive transcription factor for IME2


gazetteer

YDR017c KCS1 potential transcription factor of the BZIPtype

YGL025c PGD1 probable transcription factorYER108c FLO8 probable transcriptional activator of Flo1pYGL194c RTL1 putative deacetylase YJL103c putative regulatory proteinYBL066c SEF1 putative transcription factorYHR056c putative transcription regulatorYBR275c RIF1 Rap1p-interacting factor 1YKL038w RGT1 regulator of glucose induced genesYDR257c RMS1 regulatory proteinYDR392w SPT3 regulatory proteinYMR016c SOK2 regulatory protein in the PKA signal

transduction pathwayYCL055w KAR4 regulatory protein required for pheromone

induction of karyogamy genesYNR052c POP2 required for glucose derepressionYMR179w SPT21 required for normal transcription at a

number of lociYKL093w MBR1 required for optimal growth on glycerolYOL068c HST1 silencing proteinYOR025w HST3 silencing proteinYBL052c SAS3 silencing proteinYKR101w SIR1 silencing regulatory proteinYDL042c SIR2 silencing regulatory proteinYLR442c SIR3 silencing regulatory proteinYDR227w SIR4 silencing regulatory proteinYKL070w similarity to B. subtilis transcriptional

regulatory proteinYDL070w similarity to bromodomain protein BDF1YIL131c FKH1 similarity to D. melanogaster fork head

proteinYJL056c similarity to developmental control

proteinsYBR061c similarity to E. coli ftsJ proteinYJR147w similarity to heat-shock transcription

factorsYGR249w MGA1 similarity to heat-shock transcription

factorsYPL015c HST2 similarity to Hst1p and Sir2pYDR191w HST4 similarity to Hst3p,Hst1p and Sir2pYNL107w similarity to human AF-9 proteinYHR193c EGD2 similarity to human α-NACYAR003w FUN16 similarity to human RB protein binding

proteinYER169w similarity to human retinoblastoma

binding protein 2YJR119c similarity to human retinoblastoma

binding protein 2YLR116w similarity to human ZFM1 protein and

mouse CW17R proteinYJL206c similarity to hypothetical protein YIL130p

and Put3pYOL133w similarity to Lotus RING-finger proteinYER130c similarity to Msn2p and Msn4pYER184c similarity to multidrug resistance protein

PDR3YIL050w similarity to N. crassa regulatory protein

preg(+)YLR013w similarity to nitrogen regulatory proteinsYDR334w similarity to nuclear Sth1p, Snf2p and

related proteinsYPR115w similarity to probable transcription factor

Ask10p, and to hypothetical proteinsYNL047c and YIL105c

YIL130w similarity to Put3p and to hypotheticalprotein YJL206c

YCR020c PET18 similarity to regulatory proteinYBR182c similarity to Rlm1p,Mcm1p, and hMEF2YKR008w similarity to S. pombe bromodomain

proteinYGL150c similarity to Snf2p and human SNF2αYLR228c similarity to transcription activator Lys14pYLL054c similarity to transcription factor Pip2pYLR266c similarity to transcription factorsYLR278c similarity to transcription factorsYDR303c similarity to transcriptional regulator

proteinsYMR019w STB4 SIN3 binding proteinYHR178w STB5 SIN3 binding proteinYKL072w STB6 SIN3 binding proteinYNL309w STB1 Sin3p binding proteinYMR053c STB2 Sin3p binding proteinYLR399c BDF1 sporulation proteinYNL204c SPS18 sporulation-specific zinc-finger proteinYMR037c stress responsive regulatory proteinYDR026c strong similarity to DNA-binding protein

Reb1pYDR252w BTT1 strong similarity to Egd1p and to human

Btf3 proteinYHR211w FLO5 strong similarity to Flo1pYOR304w strong similarity to human Snf2p

homologueYOL055c strong similarity to hypothetical proteins

YPL258c, YPR121w, similarity to B. subtilistranscriptional activator tenA

YFL052w strong similarity to Mal63p, Mal23p andMal33p

YPR196w strong similarity to regulatory proteinMal63p

YBR245c strong similarity to SNF2/SWI2 DNAbinding regulatory protein

YDR253c strong similarity to zinc-finger proteinsYML081w strong similarity to ZMS1 proteinYEL056w HAT2 subunit of the major yeast histone

acetyltransferaseYOR213c subunit of the RSC complexYCR052w RSC6 subunit of the RSC complex

YFR037c RSC8 subunit of the RSC complexYLR321c SFH1 subunit of the RSC complexYIL126w STH1 subunit of the RSC complexYGL254w FZF1 sulphite resistance proteinYNL222w SSU72 suppressor of cs mutant sua7YDR310c SUM1 suppressor of mar1-1YKR099w BAS1 transcription factorYDL165w CDC36 transcription factorYLR098c CHA4 transcription factorYPL248c GAL4 transcription factorYFL031w HAC1 transcription factorYLR256w HAP1 transcription factorYCR065w HCM1 transcription factorYLR451w LEU3 transcription factorYGL013c PDR1 transcription factorYKL043w PHD1 transcription factorYFR034c PHO4 transcription factorYBR049c REB1 transcription factorYBL093c ROX3 transcription factorYOR140w SFL1 transcription factorYLR055c SPT8 transcription factorYER111c SWI4 transcription factorYDR146c SWI5 transcription factorYLR182w SWI6 transcription factorYFL021w GAT1 transcription factor for nitrogen regulationYER040w GLN3 transcription factor for positive nitrogen

regulationYMR042w ARG80 transcription factor involved in arginine


metabolismYMR280c CAT8 transcription factor involved in

gluconeogenesisYGL181w GTS1 transcription factor of the


familyYPL089c RLM1 transcription factor of the MADS box

familyYLR014c PPR1 transcription factor regulating pyrimidine

pathwayYJR094c IME1 transcription factor required for

sporulationYHR206w SKN7 transcription factor with similarity to Hsf1pYDL056w MBP1 transcription factor, subunit of the MBF

factorYNL330c RPD3 transcription modifier proteinYOL004w SIN3 transcription regulatory proteinYJL127c SPT10 transcription regulatory proteinYJL176c SWI3 transcription regulatory proteinYPL082c MOT1 transcriptional accessory proteinYDR423c CAD1 transcriptional activatorYOR028c CIN5 transcriptional activatorYPL075w GCR1 transcriptional activatorYOL116w MSN1 transcriptional activatorYKL062w MSN4 transcriptional activatorYHR084w STE12 transcriptional activatorYIR023w DAL81 transcriptional activator for allantoin and

GABA catabolic genesYNL314w DAL82 transcriptional activator for allantoin

catabolic genesYDL170w UGA3 transcriptional activator for GABA

catabolic genesYML007w YAP1 transcriptional activator involved in

oxidative stress responseYEL009c GCN4 transcriptional activator of amino acid

biosynthetic genesYDR034c LYS14 transcriptional activator of lysine pathway

genesYIR017c MET28 transcriptional activator of sulphur amino

acid metabolismYNL103w MET4 transcriptional activator of sulphur

metabolismYPR104c FHL1 transcriptional activator of the

forkhead/hnf3 familyYDR448w ADA2 transcriptional adaptorYMR039c SUB1 transcriptional coactivatorYAL021c CCR4 transcriptional regulatorYER164w CHD1 transcriptional regulatorYIL084c SDS3 transcriptional regulatorYNL012w SPO1 transcriptional regulator involved in

sporulationYGL035c MIG1 transcriptional repressorYER068w MOT2 transcriptional repressorYKR034w DAL80 transcriptional repressor for allantoin and

GABA catabolic genesYMR182c RGM1 transcriptional repressor proteinYCL054w transcriptional silencing proteinYBR083w TEC1 Ty transcription activatorYOR337w TEA1 TY1 enhancer activatorYER151c UBP3 ubiquitin-specific proteinaseYER088c weak similarity human transforming

proteins (B-myb)YBR240c weak similarity to regulatory proteinsYML076c weak similarity to transcription factorYCR106w weak similarity to transcription factor

Pip2pYBR033w weak similarity to transcription factorsYKR064w weak similarity to transcription factorsYOL089c weak similarity to transcription factorsYKL222c weak similarity to transcription factors,

similarity to finger proteins YOR162c,YOR172w and YLR266c

YBL054w weak similarity transforming protein (B-myb)

YER122c GLO3 zinc-finger proteinYDR216w ADR1 zinc-finger transcription factorYGR044c RME1 zinc-finger transcription factor

cchhrroommaattiinn mmooddiiffiiccaattiioonnYBR195c MSI1 chromatin assembly complex, subunit

p50YML102w CAC2 chromatin assembly complex, subunit


p90YGL207w SPT16 general chromatin factorYGR252w GCN5 histone acetyltransferaseYGL194c RTL1 putative deacetylase YHR119w YTX1 regulatory proteinYBR238c strong similarity to general chromatin

factor Spt16pYFR004w MPR1 strong similarity to S. pombe pad1 proteinYOR213c subunit of the RSC complexYCR052w RSC6 subunit of the RSC complexYFR037c RSC8 subunit of the RSC complexYLR321c SFH1 subunit of the RSC complexYIL126w STH1 subunit of the RSC complexYGR274c TAF145 TFIID subunit (TBP-associated factor),

145KYGR063c SPT4 transcription initiation proteinYML010w SPT5 transcription initiation proteinYGR116w SPT6 transcription initiation protein

mRNA processing (splicing)

YBL074c AAR2 A1 cistron splicing factorYHL038c CBP2 apo-cytochrome b pre-mRNA processing

protein 2YPL119c DBP1 ATP-dependent RNA helicaseYOR204w DED1 ATP-dependent RNA helicaseYBR142w MAK5 ATP-dependent RNA helicaseYPL029w SUV3 ATP-dependent RNA helicase,

mitochondrialYNL286w CUS2 cold sensitive U2 snRNA suppressorYIR021w MRS1 involved in mitochondrial RNA splicing of

COB mRNAYOR148c SPP2 involved in pre-mRNA processingYPR057w BRR1 involved in snRNP biogenesisYLR382c NAM2 leucine-tRNA ligase, mitochondrialYNL210w MER1 meiotic recombination proteinYHR086w NAM8 meiotic recombination proteinYMR023c MSS1 mitochondrial GTPase involved in

expression of COX1YLL036c PRP19 non-snRNP sliceosome component

required for DNA repairYBR237w PRP5 pre-mRNA processing RNA-helicaseYKL074c MUD2 pre-mRNA splicing factorYDL043c PRP11 pre-mRNA splicing factorYJL203w PRP21 pre-mRNA splicing factorYER013w PRP22 pre-mRNA splicing factorYMR268c PRP24 pre-mRNA splicing factorYGR075c PRP38 pre-mRNA splicing factorYML046w PRP39 pre-mRNA splicing factorYDL030w PRP9 pre-mRNA splicing factor (snRNA-

associated protein)YDR088c SLU7 pre-mRNA splicing factor affecting 3’

splice site choiceYDR243c PRP28 pre-mRNA splicing factor RNA helicase of

DEAD box familyYGR091w PRP31 pre-mRNA splicing proteinYDL044c MTF2 protein involved in mRNA splicing and

protein synthesis, mitochondrialYBR091c MRS5 regulator of intron splicing, mitochondrialYDR028c REG1 regulatory subunit for protein

phosphatase Glc7pYDR478w SNM1 RNA binding protein of RNase MRPYDR194c MSS116 RNA helicase of the DEAD box family,

mitochondrialYER172c BRR2 RNA helicase-related proteinYOR334w MRS2 RNA splicing protein and member of the

mitochondrial carrier family (MCF)YJL133w MRS3 RNA splicing protein and member of the

mitochondrial carrier family (MCF)YKR052c MRS4 RNA splicing protein and member of the

mitochondrial carrier family (MCF)YKR086w PRP16 RNA-dependent ATPaseYNR011c PRP2 RNA-dependent ATPase of DEAH box

familyYHR004c-a similarity to mitochondrial splicing protein

Mrs5pYKR024c similarity to pre-mRNA processing protein

Prp5pYGR074w SMD1 snRNA-associated proteinYPR182w SMX3 snRNA-associated protein of the SM

familyYBR055c PRP6 snRNP(U4/U6)-associated splicing factorYKL012w PRP40 splicing factorYPR134w MSS18 splicing proteinYGR222w PET54 splicing protein and translational activator,

mitochondrialYKL078w strong similarity to ATP-dependent RNA

helicasesYOR159c SME1 strong similarity to human small nuclear

ribonucleoprotein EYLR275w strong similarity to human snRNP subunit

D2 involved in systemic lupuserythematosus

YPL060w strong similarity to Mrs2pYGL120c strong similarity to Prp22pYLR147c SMD3 strong similarity to small nuclear

ribonucleoprotein D3YIR009w MSL1 strong similarity to small nuclear

ribonucleoproteinsYIL061c SNP1 U1 small nuclear ribonucleoproteinYBR119w MUD1 U1 snRNP-specific A proteinYMR240c CUS1 U2 snRNP protein


gazetteer

YPR178w PRP4 U4/U6 snRNP 52K proteinYGR006w PRP18 U5 snRNA-associated proteinYHR165c PRP8 U5 snRNP protein, pre-mRNA splicing

factorYER112w USS1 U6 snRNA associated protein

mRNA processing (5’-end, 3’-end processingand mRNA degradation)

YJL209w CBP1 apo-cytochrome b pre-mRNA processingprotein

YBR120c CBP6 apo-cytochrome b pre-mRNA processingprotein

YPL178w SAE1 cell cycle block in meiotic prophaseYGL094c PAN2 component of Pab1p-stimulated poly(A)

ribonucleaseYMR061w RNA14 component of pre-mRNA 3’-end

processing factorYGL044c RNA15 component of pre-mRNA 3’-end

processing factorYJR093c FIP1 component of pre-mRNA polyadenylation

factorYKL025c PAN3 component of the Pab1p-dependent poly

(A)YOL149w DCP1 component of the yeast decapping

enzymeYGL097w SRM1 GDP/GTP exchange factor for

Gsp1p/Gsp2pYGR158c MTR3 involved in mRNA transportYBR236c ABD1 methyltransferaseYGL130w CEG1 mRNA guanylyltransferase (mRNA

capping enzyme, α subunit)YER165w PAB1 mRNA polyadenylate-binding proteinYLR277c BRR5 mRNA processing proteinYKR002w PAP1 poly(A) polymeraseYGL122c NAB2 poly(A)-binding proteinYPL190c NAB3 polyadenylated RNA-binding proteinYDR301w CFT1 pre-mRNA 3’-end processing factorYJR017c ESS1 processing/termination factor 1YDR195w REF2 RNA 3’-end formation proteinYOR179c similarity to BRR5 proteinYOR319w HSH49 similarity to human SAP49 and RNA-

binding proteinsYHR015w similarity to PES4 PAB-like proteinYOR159c SME1 strong similarity to human small nuclear

ribonucleoprotein E

other mRNA-transcription activities

YGL171w ROK1 ATP-dependent RNA helicaseYOL006c TOP1 DNA topoisomerase IYGL251c HFM1 DNA/RNA helicaseYNL037c IDH1 isocitrate dehydrogenase (NAD+) subunit


2, mitochondrialYNL016w PUB1 major polyadenylated RNA-binding protein

of nucleus and cytoplasmYHR170w NMD3 nonsense-mediated mRNA decay proteinYMR064w AEP1 nuclear control of ATPase messenger

RNA expression proteinYOL123w HRP1 polyadenylated RNA-binding proteinYLR067c PET309 required for stability and translation of

COX1 mRNAYAL016w TPD3 ser/thr phosphatase 2A, regulatory

subunit AYOL042w similarity to CCR4 proteinYER146w similarity to human snRNP EYER029c similarity to human snRNP-associated

protein BYER028c similarity to Mig1pYDR429c similarity to nuclear RNA binding proteinsYJR127c ZMS1 similarity to regulatory protein ADR1YDL031w similarity to RNA helicasesYNL147w similarity to snRNP proteinsYNL021w similarity to transcription factor Rpd3pYPR068c similarity to transcription factor Rpd3pYPL213w similarity to U2 snRNP protein A’YBL026w SNP3 snRNP-related proteinYDL160c DHH1 strong similarity to RNA helicases of the

DEAD box familyYLR147c SMD3 strong similarity to small nuclear

ribonucleoprotein D3YLR139c SLS1 suppresses lethality of SSM4 deletion

RNA transport

YGL097w SRM1 GDP/GTP exchange factor forGsp1p/Gsp2p

YMR235c RNA1 GTPase activating proteinYOR185c GSP2 GTP-binding proteinYLR293c GSP1 GTP-binding protein of the ras

superfamilyYOR160w MTR10 involved in mRNA transportYGR158c MTR3 involved in mRNA transportYJL050w MTR4 involved in nucleocytoplasmic transport of

mRNAYKL186c MTR2 mRNA transport proteinYKL068w NUP100 nuclear pore proteinYKL057c NUP120 nuclear pore proteinYKR082w NUP133 nuclear pore proteinYGL092w NUP145 nuclear pore proteinYDR192c NUP42 nuclear pore proteinYGL172w NUP49 nuclear pore proteinYJL061w NUP82 nuclear pore proteinYDR432w NPL3 nucleolar proteinYGL122c NAB2 poly(A)-binding proteinYKL205w LOS1 pre-tRNA splicing protein

YER110c KAP123 RAN-binding proteinYDR002w YRB1 ran-specific GTPase-activating proteinYER107c GLE2 required for nuclear pore complex

structure and functionYIR011c STS1 required for transport of Rna15p from the

cytoplasm to the nucleusYDL207w GLE1 RNA export mediatorYLR119w SRN2 suppressor of rna1-1 mutation

other transcription activities

YGL127c SOH1 allows hpr1 null mutant to grow at 37ºCYOR113w AZF1 asparagine-rich zinc-finger proteinYPR198w SGE1 drug resistance proteinYBR212w NGR1 glucose-repressible RNA-binding proteinYML027w YOX1 homoeodomain proteinYNL068c FKH2 homology to D. melanogaster forkhead

proteinYIL030c SSM4 involved in mRNA turnoverYNL282w (POP2) involved in processsing RNAsYCR087c-a nucleic acid-binding proteinYDL051w YLA1 RNA binding proteinYMR164c similarity to CYC8 proteinYGL014w similarity to D. melanogaster pumilio

protein and HTR1 proteinYIR001c similarity to D. melanogaster RNA binding

proteinYNL004w HRB1 similarity to Gbp2pYBR233w similarity to human hnRNP-E1 proteinYPR031w similarity to human zinc-finger protein

BR140YCL033c similarity to M. capricolum transcription

repressorYIR005w similarity to RNA-binding proteinsYMR213w similarity to S. pombe putative

transcription factor cdc5YNL175c similarity to S. pombe Rnp24pYOR244w similarity to SAS2 and SAS3 proteinYPR008w similarity to transcription factorYPL230w similarity to transcription factorsYPR013c similarity to transcription factorsYPR015c similarity to transcription factorsYNL027w similarity to zinc-finger proteinsYPL038w similarity to zinc-finger proteinsYDR169c STB3 SIN3 protein-binding proteinYPR107c strong similarity to D. melanogaster zinc-

finger proteinYIL105c strong similarity to hypothetical protein

YNL047c, similarity to hypothetical proteinYPR115w and to probable transcriptionfactor Ask10p

YNL255c strong similarity to nucleic acid-bindingproteins

YHR169w strong similarity to RNA helicaseYGL078c strong similarity to RNA helicase DBP2

proteinYCR004c YCP4 strong similarity to S. pombe protein obr1YFL017w-a SNP2 strong similarity to snRNP EYDR451c strong similarity to Yox1pYML017w PSP2 suppressor of DNA polymerase α

mutationYKR092c SRP40 suppressor of mutant AC40 of RNA

polymerase I and IIIYKL005c weak similarity to D. melanogaster

transcription elongation factor DmS-IIYNR063w weak similarity to CYC1/CYP3

transcription activatorYJL124c weak similarity to human Sm protein GYDR043c weak similarity to K. marxianus Mig1 and

other regulatory proteinsYIR018w weak similarity to transcription activator

Pdr4pYPR199c weak similarity to transcription activator

Yap1pYBR239c weak similarity to transcription factor

Put3pYBR150c weak similarity to transcription factorsYGR067c weak similarity to transcription factorsYPL133c weak similarity to transcription factorsYER116c zinc-finger protein

Protein synthesisribosomal proteins

YGR214w NAB1A 40S ribosomal protein p40 homologue AYLR048w NAB1B 40S ribosomal protein p40 homologue BYCR031c CRY1 40S ribosomal protein S14.eYGL189c RPS26A 40S ribosomal protein S26e.c7YML009c MRPL39A 60S ribosomal protein, mitochondrialYDL081c RPLA1 acidic ribosomal protein a1YLR340w RPLA0 acidic ribosomal protein L10.eYDL130w RPLA3 acidic ribosomal protein L44primeYDR382w RPLA4 acidic ribosomal protein L45YOL039w RPLA2 acidic ribosomal protein P2.βYOR369c RS12 acidic ribosomal protein S12YGL068w probable ribosomal protein L12YLR325c putative ribosomal protein L38YFL034c-a ribosomal proteinYFR032c-a ribosomal proteinYLR061w ribosomal proteinYMR142c ribosomal proteinYPL183w-a ribosomal proteinYLR075w GRC5 ribosomal proteinYIL133c RP22 ribosomal proteinYNL069c RP23 ribosomal protein

YOR096w RP30 ribosomal proteinYKL006w RPL14A ribosomal proteinYHL001w RPL14B ribosomal proteinYMR242c RPL18A ribosomal proteinYOR312c RPL18B ribosomal proteinYDR471w RPL27B ribosomal proteinYLR344w RPL33A ribosomal proteinYMR194w RPL39A ribosomal proteinYDL184c RPL47A ribosomal proteinYDL133c-a RPL47B ribosomal proteinYPL198w RPL6B ribosomal proteinYOL040c RPS21 ribosomal proteinYLR287c-a RPS30A ribosomal proteinYDL191w SOS1 ribosomal proteinYDL136w SOS2 ribosomal proteinYPL220w SSM1A ribosomal proteinYGL135w SSM1B ribosomal proteinYGL123w SUP44 ribosomal proteinYIL148w UBI1 ribosomal proteinYKR094c UBI2 ribosomal proteinYHL015w URP2 ribosomal proteinYML073c YL16A ribosomal proteinYLR448w YL16B ribosomal proteinYDR500c RPL35B ribosomal protein L.37.eYPR102c RPL16A ribosomal protein L11.eYDR418w RPL15A ribosomal protein L12.eYEL054c RPL15B ribosomal protein L12.eYDL082w ribosomal protein L13YKL170w MRPL38 ribosomal protein L14, mitochondrialYLR029c RPL13A ribosomal protein L15.e.c12YMR121c RPL13B ribosomal protein L15.e.c13YJL063c MRPL8 ribosomal protein L17, mitochondrialYKL180w RPL20A ribosomal protein L17.eYJL177w RPL20B ribosomal protein L17.eYNL301c RP28B ribosomal protein L18.eYBL027w RPL19A ribosomal protein L19.eYBR084c-a RPL19B ribosomal protein L19.eYPL079w URP1B ribosomal protein L21YBR191w URP1A ribosomal protein L21.eYBL087c RPL17A ribosomal protein L23.eYER117w RPL17B ribosomal protein L23.eYOL127w RPL25 ribosomal protein L23a.eYGL031c RPL30A ribosomal protein L24.e.AYGR148c RPL30B ribosomal protein L24.e.BYGR034w RPL33B ribosomal protein L26YHR010w RPL27A ribosomal protein L27.eYGL103w CYH2 ribosomal protein L27a.eYBR031w RPL2A ribosomal protein L2AYOR063w TCM1 ribosomal protein L3.eYGL030w RPL32 ribosomal protein L30.eYDL075w RPL43A ribosomal protein L31.eYLR406c RPL34B ribosomal protein L31.e.c12YBL092w ribosomal protein L32.eYIL052c ribosomal protein L34.eYOR234c RPL37B ribosomal protein L35a.e.c15YPL143w RPL37A ribosomal protein L35a.e.c16YNL162w RPL41A ribosomal protein L36a.eYHR141c RPL41B ribosomal protein L36a.eYLR185w RPL35A ribosomal protein L37.eYPR043w ribosomal protein L37a.eYJL189w RPL46 ribosomal protein L39.eYDR012w RPL2B ribosomal protein L4.e.BYPL131w RPL1 ribosomal protein L5.eYNL002c RLP7 ribosomal protein L7.eYGL076c RPL6A ribosomal protein L7.e.AYHL033c RPL4A ribosomal protein L7a.e.AYLL045c RPL4B ribosomal protein L7a.e.BYIL018w RPL5A ribosomal protein L8.eYFR031c-a RPL5B ribosomal protein L8.eYGL147c RPL9A ribosomal protein L9.eYNL067w RPL9B ribosomal protein L9.e.c14YGR076c MRPL25 ribosomal protein m (YML25),

mitochondrialYJR094w-a ribosomal protein of the large subunitYOR293w ribosomal protein S10.eYDR025w RPS18A ribosomal protein S11.eYBR048w RPS18B ribosomal protein S11.e.BYPR166c MRP2 ribosomal protein S14YJL191w CRY2 ribosomal protein S14.e.BYJL190c RPS24A ribosomal protein S15a.e.c10YLR367w RPS24B ribosomal protein S15a.e.c12YPL013c ribosomal protein S16, mitochondrialYMR143w RPS16A ribosomal protein S16.eYDL083c RPS16B ribosomal protein S16.eYML024w RP51A ribosomal protein S17.e.AYDR447c RP51B ribosomal protein S17.e.BYOL120c RP28A ribosomal protein S18.eYML026c RPS18EB ribosomal protein S18.e.c13YDR450w RPS18EA ribosomal protein S18.e.c4YOL121c RP55A ribosomal protein S19.eYNL302c RP55B ribosomal protein S19.eYKR057w RPS25A ribosomal protein S21.eYJL136c RPS25B ribosomal protein S21.eYGR118w RPS28A ribosomal protein S23.eYPR132w RPS28B ribosomal protein S23.eYER074w RP50A ribosomal protein S24.eYIL069c RP50B ribosomal protein S24.eYLR333c RPS31B ribosomal protein S25.e.c12YGR027c RPS31A ribosomal protein S25.e.c7YER131w RPS26B ribosomal protein S26e-c5YKL156w RPS27A ribosomal protein S27.eYHR021c RPS27B ribosomal protein S27.eYDR064w YS15 ribosomal protein S27AYLR264w RPS33B ribosomal protein S28.e.c12YOR167c RPS33A ribosomal protein S28.e.c15YLR388w YS29A ribosomal protein S29.e.AYDL061c YS29B ribosomal protein S29.e.BYNL178w RPS3 ribosomal protein S3.e


gazetteer

YLR441c RP10A ribosomal protein S3a.eYML063w RP10B ribosomal protein S3a.eYJR145c RPS7B ribosomal protein S4.e.c10YHR203c RPS7A ribosomal protein S4.e.c8YBR251w MRPS5 ribosomal protein S5, mitochondrialYJR123w RPS5 ribosomal protein S5.eYBR181c RPS101 ribosomal protein S6.eYPL090c RPS10B ribosomal protein S6.eYBL072c RPS8A ribosomal protein S8.eYER102w RPS8B ribosomal protein S8.eYBR146w MRPS9 ribosomal protein S9, mitochondrialYPL081w RPS13B ribosomal protein S9.e.AYBR189w SUP46 ribosomal protein S9.e.BYGR085c RPL16B ribosomal protein YL16.BYKR006c MRPL13 ribosomal protein YmL13, mitochondrialYNL005c MRPL2 ribosomal protein YmL2, mitochondrialYKR085c MRPL20 ribosomal protein YmL20, mitochondrialYBR282w MRPL27 ribosomal protein YmL27, mitochondrialYDR462w ribosomal protein YmL28, mitochondrialYNL252c ribosomal protein YmL30, mitochondrialYKL138c MRPL31 ribosomal protein YmL31, mitochondrialYCR003w MRPL32 ribosomal protein YmL32, mitochondrialYBR122c MRPL36 ribosomal protein YmL36, mitochondrialYBR268w MRPL37 ribosomal protein YmL37, mitochondrialYPL173w ribosomal protein YmL40, mitochondrialYMR225c MRPL44 ribosomal protein YmR44, mitochondrialYPL249c-a RPL39B ribosomal protein, cytoplasmicYML025c ribosomal protein, mitochondrialYDR347w MRP1 ribosomal protein, mitochondrialYGR084c MRP13 ribosomal protein, mitochondrialYKL003c MRP17 ribosomal protein, mitochondrialYDR405w MRP20 ribosomal protein, mitochondrialYHL004w MRP4 ribosomal protein, mitochondrialYKL167c MRP49 ribosomal protein, mitochondrialYKL142w MRP8 ribosomal protein, mitochondrialYLR312w-a MRPL15 ribosomal protein, mitochondrialYBL038w MRPL16 ribosomal protein, mitochondrialYMR193w MRPL24 ribosomal protein, mitochondrialYMR024w MRPL3 ribosomal protein, mitochondrialYMR286w MRPL33 ribosomal protein, mitochondrialYLR439w MRPL4 ribosomal protein, mitochondrialYHR147c MRPL6 ribosomal protein, mitochondrialYGR220c MRPL9 ribosomal protein, mitochondrialYDR337w MRPS28 ribosomal protein, mitochondrialYNL137c NAM9 ribosomal protein, mitochondrialYOR158w PET123 ribosomal protein, mitochondrialYCR046c PETCR46 ribosomal protein, mitochondrialYFR049w YMR31 ribosomal protein, mitochondrialYJR113c similarity to mitochondrial ribosomal

protein S7YHR148w similarity to ribosomal proteinYDR116c similarity to ribosomal protein L1YOR150w similarity to ribosomal protein L13YNL284c similarity to ribosomal protein L15YEL050c similarity to ribosomal protein L2YLR009w similarity to ribosomal protein L24.e.BYDR115w similarity to ribosomal protein L34YDR237w similarity to ribosomal protein L5YNL081c similarity to ribosomal protein S13YDR041w similarity to ribosomal proteinsYKL009w similarity to Rpl10p and S.solfataricus

ribosomal protein L10YDL208w NHP2 strong similarity to high-mobility group

(HMG) familyYEL026w strong similarity to high-mobility group-like

protein Nhp2pYOR182c RPS30B strong similarity to human ubiquitin-like

protein/ribosomal protein S30YNR037c strong similarity to Mycoplasma

ribosomal protein S19YNL185c strong similarity to ribosomal protein L11YER056c-a strong similarity to ribosomal protein

L34.eYMR230w strong similarity to ribosomal protein S10YNR036c strong similarity to ribosomal protein S12YNL096c strong similarity to ribosomal protein S7YLR167w UBI3 ubiquitin/ribosomal protein S27aYMR188c weak similarity to 30S ribosomal protein

S17YDL202w weak similarity to ribosomal protein

translation (initiation, elongation andtermination)

YDL081c RPLA1 acidic ribosomal protein a1YMR309c NIP1 associated with 40s ribosomal subunitYGL094c PAN2 component of Pab1p-stimulated poly(A)

ribonucleaseYDR172w SUP35 eukaryotic peptide chain release factor

GTP-binding subunitYNL007c SIS1 heat-shock proteinYBL091c MAP2 methionine aminopeptidase, isoform 2YMR023c MSS1 mitochondrial GTPase involved in

expression of COX1YGL143c MRF1 mitochondrial peptide chain release factorYGL049c TIF4632 mRNA cap-binding protein (eIF4F), 130K

subunitYGR162w TIF4631 mRNA cap-binding protein (eIF4F), 150K

subunitYOR276w CAF20 mRNA CAP-binding protein (eIF4F), 20K

subunitYER165w PAB1 mRNA polyadenylate-binding proteinYKL173w GIN10 similarity to elongation factor 2 eFT1YHR015w similarity to PES4 PAB-like proteinYGR201c similarity to Tef3p and Tef4pYPL226w similarity to translation elongation factor

eEF3

YLR289w GUF1 strong similarity to E. coli elongationfactor-type GTP-binding protein lepa

YDL084w strong similarity to nuclear RNA helicase(DEAD family)

YDR021w strong similarity to translation initiationfactor eIF4A

YKL010c SOS1 suppressor of sis1YLR005w SSL1 TFIIH subunit (transcription initiation

factor), factor BYKR084c HBS1 translation elongation factor eEF1

α subunit homologueYPR080w TEF1 translation elongation factor eEF1

α-A subunit, cytosolicYBR118w TEF2 translation elongation factor eEF1

α-A subunit, cytosolicYPL048w CAM1 translation elongation factor eEF1,

α subunitYKL081w TEF4 translation elongation factor eEF1,

γ subunitYAL003w EFB1 translation elongation factor eEF1βYOR133w EFT1 translation elongation factor eEF2YDR385w EFT2 translation elongation factor eEF2YLR249w YEF3 translation elongation factor eEF3YNL014w translation elongation factor eEF3

homologueYNL163c translation elongation factor eEF4YLR069c MEF1 translation elongation factor G,

mitochondrialYOR187w TUF1 translation elongation factor TU,

mitochondrialYJL102w MEF2 translation elongation factor,

mitochondrialYOL023w IFM1 translation initiation factor 2, mitochondrialYNL244c SUI1 translation initiation factor 3 (eIF3)YKR059w TIF1 translation initiation factor 4AYMR260c TIF11 translation initiation factor eIF1AYPL237w SUI3 translation initiation factor eIF2 β subunitYJR007w SUI2 translation initiation factor eIF2, α subunitYER025w GCD11 translation initiation factor eIF2, γ subunitYKR026c GCN3 translation initiation factor eIF2B, 34K,

α subunitYLR291c GCD7 translation initiation factor eIF2B, 43K

subunitYGR083c GCD2 translation initiation factor eIF2B, 71K (δ)

subunitYDR211w GCD6 translation initiation factor eIF2B, ε 81K

subunitYOR260w GCD1 translation initiation factor eIF2B, γ subunitYOR361c PRT1 translation initiation factor eIF3 subunitYMR146c TIF34 translation initiation factor eIF3, P39

subunitYNL062c GCD10 translation initiation factor eIF3, RNA-

binding subunitYJL138c TIF2 translation initiation factor eIF4AYPR163c TIF3 translation initiation factor eIF4BYOL139c CDC33 translation initiation factor eIF4EYPR041w TIF5 translation initiation factor eIF5YEL034w HYP2 translation initiation factor eIF5A.1YJR047c ANB1 translation initiation factor eIF5A.2YGL169w SUA5 translation initiation proteinYBR143c SUP45 translational release factor

translational control

YMR282c AEP2 2’-O-ribosyl phosphate transferaseYBR120c CBP6 apo-cytochrome b pre-mRNA processing

proteinYPL029w SUV3 ATP-dependent RNA helicase,

mitochondrialYOR017w PET127 component of mitochondrial translation

systemYMR028w TAP42 component of the Tor signalling pathwayYDR197w CBS2 cytochrome b translational activator

proteinYNL216w RAP1 DNA-binding protein with repressor and

activator activityYER054c GIP2 Glc7p-interacting proteinYMR080c NAM7 nonsense-mediated mRNA decay proteinYGR072w UPF3 nonsense-mediated mRNA decay proteinYHR077c NMD2 nonsense-mediated mRNA decay protein

2YMR064w AEP1 nuclear control of ATPase messenger

RNA expression proteinYPL179w PPQ1 phosphoprotein phosphataseYFR009w GCN20 positive effector of Gcn2pYLR203c MSS51 possibly involved in translational

activation of COX1 and COB mRNAYBL058w SHP1 potential regulatory subunit for Glc7pYNL139c RLR1 regulatory proteinYLR067c PET309 required for stability and translation of

COX1 mRNAYMR257c PET111 required for translation of COX2 mRNAYER133w GLC7 ser/thr phosphoprotein phosphatase 1,


regulatory subunit YDR283c GCN2 ser/thr protein kinaseYGR222w PET54 splicing protein and translational activator,

mitochondrialYBR024w SCO2 strong similarity to Sco1pYGL195w GCN1 translational activatorYDL069c CBS1 translational activator of cob mRNAYER153c PET122 translational activator of cytochrome c

oxidase subunit IIIYNR045w PET494 translational activator, mitochondrialYJL125c GCD14 translational repressor of GCN4

tRNA synthetases

YOR335c ALA1 alanyl-tRNA synthetase, cytosolicYHR091c MSR1 arginyl-tRNA synthetase, mitochondrialYCR024c asn-tRNA synthetase, mitochondrialYHR019c DED81 asparaginyl-tRNA-synthetaseYPL104w MSD1 aspartate-tRNA ligase, mitochondrialYLL018c DPS1 aspartyl-tRNA synthetase, cytosolicYOR168w GLN4 glutaminyl-tRNA synthetaseYOL033w MSE1 glutamyl-tRNA synthetase, mitochondrialYBR121c GRS1 glycine-tRNA ligaseYPR033c HTS1 histidine-tRNA ligase, mitochondrialYPL040c ISM1 isoleucine-tRNA ligase, mitochondrialYBL076c ILS1 isoleucyl-tRNA synthetaseYPL160w CDC60 leucine-tRNA ligase, cytosolicYLR382c NAM2 leucine-tRNA ligase, mitochondrialYDR037w KRS1 lysyl-tRNA synthetase, cytosolicYNL073w MSK1 lysyl-tRNA synthetase, mitochondrialYGR264c MES1 methionyl-tRNA synthetaseYGR171c MSM1 methionyl-tRNA synthetaseYPR047w MSF1 phenylalanine-tRNA ligase α subunit,

mitochondrialYFL022c FRS2 phenylalanine-tRNA ligase β subunit,

cytosolicYLR060w FRS1 phenylalanyl-tRNA synthetase, α subunit,

cytosolicYHR011w seryl-tRNA synthetaseYDR023w SES1 seryl-tRNA synthetase, cytosolicYNL247w similarity to cysteinyl-tRNA synthetasesYER087w similarity to E. coli prolyl-tRNA synthetaseYDR341c strong similarity to arginine-tRNA ligase

and mitochondrial arginyl-tRNAsynthetase

YGL245w strong similarity to glutamine-tRNA ligaseYPR081c strong similarity to glycyl-tRNA

synthetasesYHR020w strong similarity to human glutamyl-prolyl-

tRNA synthetaseYKL194c MST1 threonine-tRNA ligase, mitochondrialYIL078w THS1 threonyl tRNA synthetase, cytosolicYOL097c WRS1 tryptophan-tRNA ligaseYDR268w MSW1 tryptophanyl-tRNA synthetase,

mitochondrialYPL097w MSY1 tyrosyl-tRNA synthetaseYGR185c TYS1 tyrosyl-tRNA synthetaseYGR094w VAS1 valyl-tRNA synthetase

other protein-synthesis activities

YDL229w SSB1 heat-shock protein of HSP70 familyYNL209w SSB2 heat-shock protein of HSP70 family,

cytosolicYGR147c NAT2 N-acetyltransferase for N-terminal

methionineYJR066w TOR1 phosphatidylinositol 3-kinaseYDL044c MTF2 protein involved in mRNA splicing and

protein synthesis, mitochondrialYDL040c NAT1 protein N-acetyltransferase subunitYJL023c PET130 protein synthesis protein, mitochondrialYMR005w MPT1 required for protein synthesisYBL080c PET112 required to maintain RHO+ mitochondrial

DNAYHR189w similarity to peptidyl-tRNA hydrolasesYLL039c UBI4 ubiquitin

Protein destinationprotein folding and stabilization

YEL030w heat-shock protein of HSP70 familyYKL073w LHS1 chaperone of the ER lumenYIL142w CCT2 chaperonin of the TCP1 ring complex,

cytosolicYJL014w CCT3 chaperonin of the TCP1 ring complex,

cytosolicYDR212w CCT1 component of chaperonin-containing

T-complexYDL143w CCT4 component of chaperonin-containing

T-complexYJL111w CCT7 component of chaperonin-containing

T-complexYJL008c CCT8 component of chaperonin-containing

T-complexYDR188w CCT6 component of chaperonin-containing

T-complex (ζ subunit)YDR155c CPH1 cyclophilin (peptidylprolyl isomerase)YML078w CPR3 cyclophilin (peptidylprolyl isomerase),

mitochondrialYOR288c MPD1 disulphide isomerase related proteinYER048c CAJ1 dnaJ homologueYDR519w FKB2 FK506/rapamycin-binding protein of the

ERYFL016c MDJ1 heat-shock protein - chaperoneYOR232w MGE1 heat-shock protein - chaperoneYLR259c HSP60 heat-shock protein - chaperone,

mitochondrialYJR045c SSC1 heat-shock protein 70-related protein,

mitochondrialYAL005c SSA1 heat-shock protein of HSP70 familyYLL024c SSA2 heat-shock protein of HSP70 family,

cytosolicYDR171w HSP42 heat-shock protein with similarity to

Hsp26pYLR216c CPR6 member of the cyclophilin familyYJR032w CPR7 member of the cyclophilin familyYJL034w KAR2 nuclear fusion protein


gazetteer

YHR057c CYP2 peptidyl-prolyl cis-trans isomeraseYCR069w SCC3 peptidyl-prolyl cis-trans isomerase YDR304c CYP5 peptidyl-prolyl cis-trans isomerase D

(cyclophilin D) of the ERYNL135c FPR1 peptidyl-prolyl cis-trans isomerase, FK506-

binding proteinYML074c NPI46 proline cis-trans isomeraseYDR518w EUG1 protein disulphide isomeraseYCL043c PDI1 protein disulphide-isomerase YJR097w similarity to Caj1pYBR044c similarity to chaperonin HSP60 proteinsYOL088c similarity to disulphide isomerases and

ER60 proteasesYNL077w similarity to dnaJ protein homologue YDJ1YMR161w HLJ1 similarity to dnaJ proteinsYIR004w similarity to DNAJ-like proteinsYLR090w XDJ1 similarity to E. coli dnaJYJL073w similarity to heat-shock proteinsYNR028w similarity to peptidylprolyl isomerase

Scc3pYIL005w similarity to protein disulphide isomerasesYLR369w strong similarity to heat-shock protein 70-

related proteinsYLR449w strong similarity to peptidylprolyl

isomerase FRP3YJR064w CCT5 T-complex protein 1, ε subunitYFR041c weak similarity to dnaJ-like heat-shock

proteinsYNL227c weak similarity to dnaJ-like proteins

protein targeting, sorting and translocation

YKL073w LHS1 chaperone of the ER lumenYGL206c CHC1 clathrin heavy chainYOL062c APM4 clathrin-associate protein YAP54YPL259c APM1 clathrin-associated proteinYBR288c APM3 clathrin-associated protein complex,

medium subunitYDL212w SHR3 endoplasmic reticulum membrane proteinYBL040c ERD2 ER lumen protein-retaining receptorYER019c-a SEB2 ER protein-translocation complex subunitYLR378c SEC61 ER protein-translocation complex subunitYPL094c SEC62 ER protein-translocation complex subunitYOR254c SEC63 ER protein-translocation complex subunitYBR171w SEC66 ER protein-translocation complex subunitYLR292c SEC72 ER protein-translocation complex subunitYDR086c SSS1 ER protein-translocation complex subunitYOR089c VPS21 GTP-binding proteinYKR014c YPT52 GTP-binding protein of the RAB familyYNL093w YPT53 GTP-binding protein of the RAB family

(RAS superfamily)YOR270c VPH1 H+-ATPase V0 domain 95K subunit,

vacuolar YAL005c SSA1 heat-shock protein of HSP70 familyYCR075c ERS1 intracellular protein transport proteinYGR028w MSP1 intra-mitochondrial sorting proteinYOR069w VPS5 involved in Golgi retention and vacuolar

sortingYLR347c KAP95 karyopherin-βYOL122c SMF1 manganese transporterYKR001c VPS1 member of the dynamin family of

GTPasesYOR020c HSP10 mitochondrial chaperoninYNR017w MAS6 mitochondrial inner membrane import

translocase subunitYJL143w TIM17 mitochondrial inner membrane import

translocase subunitYIL022w TIM44 mitochondrial inner membrane import

translocase subunitYMR035w IMP2 mitochondrial inner membrane protease

subunitYNL131w TOM22 mitochondrial outer membrane import

receptor subunitYGR082w TOM20 mitochondrial outer membrane import

receptor subunit, 20KYMR060c TOM37 mitochondrial outer membrane import

receptor subunit, 37KYMR203w TOM40 mitochondrial outer membrane import

receptor subunit, 40KYOR045w TOM6 mitochondrial outer membrane import

receptor subunit, 6KYNL070w TOM7 mitochondrial outer membrane import

receptor subunit, 7KYNL121c TOM70 mitochondrial outer membrane

specialized import receptorYMR150c IMP1 mitochondrial proteaseYJL034w KAR2 nuclear fusion proteinYMR091c NPL6 nuclear protein localization factorYBR170c NPL4 nuclear protein localization factor and ER

translocation componentYDR432w NPL3 nucleolar proteinYLR191w PAS20 peroxisomal protein involved in protein

importYPR047w MSF1 phenylalanine-tRNA ligase α subunit,

mitochondrialYNL106c PIE3 phosphatidylinositol phosphate

phosphataseYBL069w AST1 PMA1 protein targeting proteinYLR168c (MSF1) probably involved in intramitochondrial

protein sortingYDR244w PAS10 putative peroxisomal targeting signal

receptorYCL001w RER1 required for correct localization of Sec12pYDR414c ERD1 required for retention of luminal ER

proteinsYDR005c MAF1 required for sorting of Mod5pYMR004w MVP1 required for vacuolar protein sortingYDR498c SEC20 secretory pathway protein

YBR162w-a YSY6 secretory pathway proteinYBR097w VPS15 ser/thr protein kinaseYPL243w SRP68 signal recognition particle proteinYPL210c SRP72 signal recognition particle proteinYDR292c SRP101 signal recognition particle receptor, α

subunitYML105c SEC65 signal recognition particle subunitYDL092w SRP14 signal recognition particle subunitYKL122c SRP21 signal recognition particle subunitYPR088c SRP54 signal recognition particle subunitYOR285w similarity to D. melanogaster heat-shock

protein 67B2YOR286w similarity to D. melanogaster heat-shock

protein 67B2YHR110w similarity to human gp25L2 proteinYAR002c-a similarity to mammalian gp25L proteinYKL154w similarity to mouse signal recognition

particle receptor β subunitYKL196c similarity to Sec22pYMR018w similarity to tetratricopeptide-repeat

protein PAS10YMR214w SCJ1 similarity to to E. coli dnaJYNL304w similarity to Ypt1p and other GTP-binding

proteinsYER101c AST2 strong similarity to Ast1pYOR016c strong similarity to FUN54 protein,

similarity to hamster COP-coated vesiclemembrane protein

YGL002w strong similarity to human gp25L2 proteinYER087c-a SEB1 strong similarity to mammalian Sec61β

subunitYCR099c strong similarity to Pep1pYCR100c strong similarity to Pep1pYCR101c strong similarity to Pep1pYIL173w strong similarity to Pep1pYJL222w strong similarity to Pep1pYBR283c strong similarity to Sec61pYOR327c SNC2 strong similarity to synaptobrevinYOR329c SCD5 suppressor of clathrin deficiencyYHR050w SMF2 suppressor of mitochondrial matrix

mutantYOR036w PEP12 syntaxin (T-SNARE)YLR148w PEP3 vacuolar membrane proteinYBL017c PEP1 vacuolar protein sorting/targeting proteinYJL053w PEP8 vacuolar protein sorting/targeting proteinYOR132w VPS17 vacuolar protein sorting-associated

proteinYNR006w VPS27 vacuolar protein sorting-associated

proteinYGL095c VPS45 vacuolar protein sorting-associated

proteinYJL154c VPS35 vacuolar protein-sorting proteinYDR323c PEP7 vacuolar segregation proteinYPL045w VPS16 vacuolar sorting proteinYDR495c VPS3 vacuolar sorting proteinYLR396c VPS33 vacuolar sorting proteinYAL002w VPS8 vacuolar sorting proteinYML097c VPS9 vacuolar sorting protein

protein modification (glycosylation, acylation,myristylation, palmitylation, farnesylation andprocessing)

YJR131w MNS1 α-1,2-mannosidaseYDR483w KRE2 α-1,2-mannosyltransferaseYER001w MNN1 α-1,3-mannosyltransferaseYGL038c OCH1 α-1,6-mannosyltransferaseYBR164c ARL1 ADP-ribosylation factorYKL157w APE2 aminopeptidase yscIIYJR062c NTA1 amino-terminal amidaseYGL017w ATE1 arginyl tRNA transferaseYPL154c PEP4 aspartyl proteaseYLR120c YAP3 aspergillopepsinYDL141w BPL1 biotin holocarboxylase synthetaseYBR110w ALG1 β-mannosyltransferaseYGL203c KEX1 carboxypeptidase (YSC-α)YPL227c ALG5 dolichol-P-glucose synthetaseYJR143c PMT4 dolichyl-phosphate-mannose-protein

O-mannosyl transferaseYDL212w SHR3 endoplasmic reticulum membrane proteinYNL238w KEX2 endoproteinase of late Golgi

compartmentYDR331w GPI8 essential for GPI-anchor attachmentYDR410c STE14 farnesyl cysteine carboxyl-

methyltransferaseYOR370c MSI4 geranylgeranyltransferase regulatory

subunitYGL155w CDC43 geranylgeranyltransferase type I β subunitYPR176c BET2 geranylgeranyltransferase type II β subunitYJL031c BET4 geranylgeranyltransferase, α subunitYOR002w ALG6 glucosyltransferaseYOR067c ALG8 glucosyltransferaseYEL042w GDA1 guanosine diphosphataseYGR252w GCN5 histone acetyltransferaseYPL001w HAT1 histone acetyltransferase subunitYBR034c HMT1 hnRNP methyltransferaseYAL039c CYC3 holocytochrome c synthase (cytochrome

c heme lyase)YKL087c CYT2 holocytochrome c1 synthaseYGL065c ALG2 mannosyltransferaseYDL095w PMT1 mannosyltransferaseYAL023c PMT2 mannosyltransferaseYOR321w PMT3 mannosyltransferaseYBL082c RHK1 mannosyltransferaseYLR244c MAP1 methionine aminopeptidase, isoform 1YBL091c MAP2 methionine aminopeptidase, isoform 2YMR035w IMP2 mitochondrial inner membrane protease

subunit

YKL134c (MIP1) mitochondrial intermediate peptidaseYLR163c MAS1 mitochondrial processing peptidaseYHR024c MAS2 mitochondrial processing peptidase,

catalytic 53K (α) subunitYMR150c IMP1 mitochondrial proteaseYPR051w MAK3 N-acetyltransferaseYGR147c NAT2 N-acetyltransferase for N-terminal

methionineYBR247c ENP1 N-glycosylation proteinYLR195c NMT1 N-myristoyltransferaseYJL002c OST1 oligosaccharyltransferase α subunitYEL002c WBP1 oligosaccharyltransferase β subunit YMR149w SWP1 oligosaccharyltransferase δ subunitYOR103c OST2 oligosaccharyltransferase ε subunitYOR085w OST3 oligosaccharyltransferase γ subunitYDL232w OST4 oligosaccharyltransferase subunitYGL022w STT3 oligosaccharyltransferase subunitYFL045c SEC53 phosphomannomutaseYPR122w AXL1 proteaseYEL060c PRB1 protease B, vacuolarYLR389c STE23 protease involved in a-factor processingYCL043c PDI1 protein disulphide-isomerase YKL019w RAM2 protein farnesyltransferase, α subunitYDL090c RAM1 protein farnesyltransferase, β subunitYHR013c ARD1 protein N-acetyltransferase subunitYDL040c NAT1 protein N-acetyltransferase subunitYIL085c KTR7 putative α-1,2-mannosyltransferaseYGL194c RTL1 putative deacetylase YNL029c KTR5 putative mannosyltransferaseYGR199w PMT6 putative mannosyltransferaseYKL193c SDS22 regulatory subunit for the mitotic function

of type I protein phosphataseYNL048w ALG11 required for asparagine-linked

glycosylationYLR088w GAA1 required for attachment of GPI anchor

onto proteinsYPL050c MNN9 required for complex N-glycosylationYJR010c-a SPC1 signal peptidase 10.8K subunitYML055w SPC2 signal peptidase 18K subunitYIR022w SEC11 signal sequence processing proteinYDL042c SIR2 silencing regulatory proteinYER005w similarity to Gda1pYMR223w similarity to human putative ubiquitin

carboxyl-terminal hydrolaseYDR098c similarity to Legionella glutaredoxin-like

proteinYER174c similarity to Legionella glutaredoxin-like

proteinYGL257c similarity to Mnn1pYIL014w similarity to Mnn1pYPR131c similarity to N-acetyltransferasesYDL093w PMT5 similarity to O-mannosyltransferases

Pmt1p-Pmt4pYDR307w similarity to Pmt1pYDR245w MNN10 similarity to S. pombe

galactosyltransferaseYLR066w similarity to signal peptidaseYNR059w similarity to to α-1,3-mannosyltransferaseYPL003w similarity to ubiquitin-activating enzymesYPR180w similarity to ubiquitin-activating enzymesYGL087c similarity to ubiquitin-protein ligaseYIR039c similarity to Yap3pYBR205w KTR3 strong similarity to α-1,2-

mannosyltransferaseYBR199w KTR4 strong similarity to α-1,2-

mannosyltransferaseYPL053c KTR6 strong similarity to α-1,2-

mannosyltransferase Kre2pYPL051w strong similarity to ADP-ribosylation

factorsYLR121c strong similarity to aspartylproteasesYOR099w KTR1 strong similarity to mannosyltransferasesYCR083w strong similarity to thioredoxinYOR339c strong similarity to ubiquitin conjugating

enzymesYPR066w strong similarity to ubiquitin-activating

enzymesYML111w strong similarity to ubiquitination protein

Bul1pYGL226c-a OST5 subunit of N-oligosaccharyltransferase,

ζ subunitYEL056w HAT2 subunit of the major yeast histone

acetyltransferaseYJR075w HOC1 suppressor of pkc1YLR043c TRX1 thioredoxin IYGR209c TRX2 thioredoxin IIYOR219c STE13 type IV dipeptidyl aminopeptidaseYMR275c BUL1 ubiquitination pathway proteinYDR054c CDC34 ubiquitin-conjugating enzymeYGR133w PAS2 ubiquitin-conjugating enzymeYMR022w QRI8 ubiquitin-conjugating enzymeYGL058w RAD6 ubiquitin-conjugating enzymeYDR177w UBC1 ubiquitin-conjugating enzymeYLR306w UBC12 ubiquitin-conjugating enzymeYDR092w UBC13 ubiquitin-conjugating enzymeYDR059c UBC5 ubiquitin-conjugating enzymeYER100w UBC6 ubiquitin-conjugating enzymeYEL012w UBC8 ubiquitin-conjugating enzymeYDL064w UBC9 ubiquitin-conjugating enzymeYDR139c ubiquitin-like proteinYER125w RSP5 ubiquitin-protein ligaseYKL210w UBA1 ubiquitin-protein ligaseYJR099w YUH1 ubiquitin-specific proteaseYBR243c ALG7 UDP-N-acetylglucosamine-1-phosphate

transferaseYKL035w UGP1 UTP-glucose-1-phosphate

uridylyltransferaseYDR495c VPS3 vacuolar sorting protein


gazetteer

YJR117w STE24 zinc metallo-protease

assembly of protein complexes

YGR214w NAB1A 40S ribosomal protein p40 homologue AYLR048w NAB1B 40S ribosomal protein p40 homologue BYPL195w YKS4 α- or γ- adaptin, large subunit of the

clathrin-associated protein(AP) complexYBL037w APL3 α-adaptin, large subunit of the clathrin-

associated protein(AP) complexYOR094w ARF3 ADP-ribosylation factor 3YBL022c PIM1 ATP-dependent protease, mitochondrialYKL135c APL2 β-adaptinYGR261c YKS5 β-adaptin, large subunit of the clathrin-

associated protein(AP) complexYBR195c MSI1 chromatin assembly complex, subunit


p90YLR170c APS1 clathrin-associated protein (AP) complex,

small subunit AP19YJR058c APS2 clathrin-associated protein 17, small

subunitYJR005w YAP80 clathrin-associated protein complex,

β subunitYJL024c APS3 clathrin-associated protein(AP) complex,

small subunitYER058w PET117 cytochrome c oxidase assembly factorYPL132w COX11 cytochrome c oxidase assembly proteinYML129c COX14 cytochrome c oxidase assembly proteinYDR079w PET100 cytochrome c oxidase assembly proteinYLR038c COX12 cytochrome c oxidase subunit VIBYMR256c COX7 cytochrome c oxidase subunit VIIYDL067c COX9 cytochrome c oxidase subunit VIIAYER141w COX15 cytochrome oxidase assembly factorYER154w OXA1 cytochrome oxidase biogenesis proteinYBL007c SLA1 cytoskeleton assembly control proteinYNL243w SLA2 cytoskeleton assembly control proteinYLR393w ATP10 F1F0 ATPase complex assembly proteinYNL315c ATP11 F1F0-ATPase complex assembly proteinYJL180c ATP12 F1F0-ATPase complex assembly proteinYPL172c COX10 farnesyl transferaseYPL231w FAS2 fatty-acyl-CoA synthase, α subunitYPR029c APL4 γ-adaptin, large subunit of the clathrin-

associated protein(AP) complexYDL192w ARF1 GTP-binding protein of the ARF familyYDL137w ARF2 GTP-binding protein of the ARF familyYKL119c VPH2 H+-ATPase assembly protein, vacuolarYPL234c TFP3 H+-ATPase V0 domain 17K subunit,





vacuolar YLL009c COX17 interacts genetically with SCO1 and SCO2

in cytochrome oxidase assemblyYJR034w PET191 involved in assembly of cytochrome

oxidaseYBR037c SCO1 involved in stabilization of Cox1p and

Cox2pYDR375c BCS1 mitochondrial protein of the

CDC48/PAS1/SEC18 (AAA) family ofATPases

YPL085w SEC16 multidomain vesicle coat proteinYKR048c NAP1 nucleosome assembly protein IYML102w CAC2 p60 subunit of the chromatin assembly

factor-I (CAF-I)YKL197c PAS1 peroxisomal assembly proteinYDR265w PAS4 peroxisomal assembly proteinYNL329c PAS8 peroxisomal assembly proteinYBR237w PRP5 pre-mRNA processing RNA-helicaseYJL203w PRP21 pre-mRNA splicing factorYER017c AFG3 protease of the SEC18/CDC48/PAS1

family of ATPases (AAA)YPR024w YME1 protease of the SEC18/CDC48/PAS1

family of ATPases (AAA)YMR089c YTA12 protease of the SEC18/CDC48/PAS1

family of ATPases (AAA)YPL215w CBP3 required for assembly of cytochrome bc1

complexYBR185c MBA1 respiratory chain assembly proteinYLL008w DRS1 RNA helicase of the DEAD box familyYBR227c similarity to E. coli ATP-binding protein

clpXYGR241c similarity to rat clathrin assembly proteinYHR161c similarity to rat clathrin assembly protein

AP180YGR074w SMD1 snRNA-associated proteinYBR024w SCO2 strong similarity to Sco1pYLR327c strong similarity to STF2pYOR134w BAG7 structural homologue of Sac7pYDR389w SAC7 suppressor of actin mutationYOR106w VAM3 syntaxin related proteinYDR460w TFB3 TFIIH subunit (transcription/repair factor)YPR178w PRP4 U4/U6 snRNP 52K proteinYGL119w ABC1 ubiquinol cytochrome c reductase

complex assembly proteinYPR191w QCR2 ubiquinol-cytochrome c reductase 40K

subunit IIYGR174c CBP4 ubiquinol-cytochrome c reductase

assembly factorYLL039c UBI4 ubiquitin YGR133w PAS2 ubiquitin-conjugating enzyme

YGR105w VMA21 vacuolar ATPase assembly integralmembrane protein

YHR060w VMA22 vacuolar ATPase assembly proteinYDR495c VPS3 vacuolar sorting protein

proteolysis

YPL149w APG5 involved in autophagy and nutrientstarvation

YOL013c HRD1 involved in degradation of Hmg2pYLR207w HRD3 involved in degradation of Hmg2pYMR174c PAI3 protease A (ysca) inhibitor IA3YNL015w PBI2 proteinase B inhibitor 2YCL052c PBN1 required for Prb1p expressionYHR132c similarity to carboxypeptidaseYNR069c similarity to central part of Bul1pYBR227c similarity to E. coli ATP-binding protein

clpXYNL186w similarity to human putative ubiquitin

carboxy-terminal hydrolaseYIL137c similarity to M. musculus aminopeptidaseYKR038c similarity to Qri7pYER047c similarity to regulatory subunit Yta6p of

26S proteasomeYCR045c similarity to serin proteasesYER078c similarity to X-Pro aminopeptidase IIYBR139w strong similarity to carboxypeptidaseYBL067c UBP13 ubiquitin carboxyl-terminal hydrolaseYOL111c weak similarity to human ubiquitin-like

protein GDX

ccyyttooppllaassmmiicc ddeeggrraaddaattiioonnYFR052w NIN1 26S proteasome regulatory subunitYIL075c SEN3 26S proteasome regulatory subunitYOR259c CRL13 26S proteasome subunitYPR103w PRE2 26S proteasome subunitYFR050c PRE4 26S proteasome subunitYOR157c PUP1 26S proteasome subunitYGR253c PUP2 26S proteasome subunitYER094c PUP3 26S proteasome subunitYGL048c SUG1 26S proteasome subunitYHR200w SUN1 26S proteasome subunitYER021w SUN2 26S proteasome subunitYOR117w YTA1 26S proteasome subunitYDR394w YTA2 26S proteasome subunitYKL145w YTA3 26S proteasome subunitYGR270w YTA7 26S proteasome subunitYOR362c PRE10 26S proteasome subunit C1YER012w PRE1 26S proteasome subunit C11YGR135w PRE9 26S proteasome subunit Y13YML092c PRE8 26S proteasome subunit Y7YGL011c SCL1 26S proteasome subunit YC7α/Y8YMR314w PRE5 26S proteasome subunit, α-typeYNL239w LAP3 aminopeptidase of cysteine protease

familyYJR062c NTA1 amino-terminal amidaseYGL017w ATE1 arginyl tRNA transferaseYDL132w CDC53 controls G1/S transitionYLR452c SST2 involved in desensitization to α-factor

pheromoneYKL213c DOA1 involved in ubiquitin-dependent

proteolysisYDL126c CDC48 microsomal protein of

CDC48/PAS1/SEC18 family of ATPasesYJL001w PRE3 multicatalytic endopeptidase complex

subunitYOL038w PRE6 multicatalytic endopeptidase complex

subunitYBL041w PRE7 multicatalytic endopeptidase complex

subunitYDL020c SON1 nuclear proteinYBR165w UBS1 positive regulator of Cdc34pYDL007w YTA5 probable component of 26S proteasome

complexYIL148w UBI1 ribosomal proteinYKR094c UBI2 ribosomal proteinYMR223w similarity to human putative ubiquitin

carboxyl-terminal hydrolaseYDR390c UBA2 similarity to Uba1pYPL003w similarity to ubiquitin-activating enzymesYPR180w similarity to ubiquitin-activating enzymesYGL087c similarity to ubiquitin-protein ligaseYPL074w YTA6 similarity to Vps4p and Yta4pYOR261c strong similarity to human 26S

proteasome regulatory subunit, p40YOR339c strong similarity to ubiquitin conjugating

enzymesYPR066w strong similarity to ubiquitin-activating

enzymesYML111w strong similarity to ubiquitination protein

Bul1pYHR027c HRD2 subunit of 26S proteasomeYKL022c CDC16 subunit of anaphase-promoting complex



(cyclosome)YLL039c UBI4 ubiquitin YIL156w UBP7 ubiquitin carboxy terminal hydrolaseYER098w UBP9 ubiquitin carboxyl-terminal hydrolaseYKR098c UBP11 ubiquitin C-terminal hydrolaseYJL197w UBP12 ubiquitin C-terminal hydrolaseYGR048w UFD1 ubiquitin fusion degradation proteinYDL190c UFD2 ubiquitin fusion degradation proteinYBR058c UBP14 ubiquitin specific proteaseYLR167w UBI3 ubiquitin/ribosomal protein S27aYMR275c BUL1 ubiquitination pathway protein

YDR054c CDC34 ubiquitin-conjugating enzymeYMR022w QRI8 ubiquitin-conjugating enzymeYDR177w UBC1 ubiquitin-conjugating enzymeYLR306w UBC12 ubiquitin-conjugating enzymeYDR092w UBC13 ubiquitin-conjugating enzymeYBR082c UBC4 ubiquitin-conjugating enzymeYDR059c UBC5 ubiquitin-conjugating enzymeYER100w UBC6 ubiquitin-conjugating enzymeYDL064w UBC9 ubiquitin-conjugating enzymeYDR139c ubiquitin-like proteinYER125w RSP5 ubiquitin-protein ligaseYKL210w UBA1 ubiquitin-protein ligaseYGR184c UBR1 ubiquitin-protein ligaseYDR069c DOA4 ubiquitin-specific proteaseYDL122w UBP1 ubiquitin-specific proteaseYER144c UBP5 ubiquitin-specific proteaseYJR099w YUH1 ubiquitin-specific proteaseYOR124c UBP2 ubiquitin-specific proteinaseYER151c UBP3 ubiquitin-specific proteinase

llyyssoossoommaall aanndd vvaaccuuoollaarr ddeeggrraaddaattiioonnYBR286w APE3 aminopeptidase Y, vacuolarYKL103c LAP4 aminopeptidase yscI, vacuolarYPL154c PEP4 aspartyl proteaseYMR297w PRC1 carboxypeptidase y, serine-type proteaseYHR028c DAP2 dipeptidyl aminopeptidase BYJL172w CPS1 Gly-X carboxypeptidase YSCS YEL060c PRB1 protease B, vacuolarYOR003w YSP3 subtilisin-like protease III

ootthheerr ssuubbcceelllluullaarr ddeeggrraaddaattiioonnYDR144c MKC7 aspartyl protease of the periplasmic

spaceYBL022c PIM1 ATP-dependent protease, mitochondrialYIL015w BAR1 barrierpepsin YBR201w DER1 involved in degradation proteins in the ERYER017c AFG3 protease of the SEC18/CDC48/PAS1



family of ATPases (AAA)YCL057w PRD1 proteinase yscDYHR113w similarity to vacuolar aminopeptidase

Lap4p/Ape1pYFR006w similarity to X-Pro dipeptidases

other protein-destination activities

YDR258c HSP78 heat-shock protein of clpb family of ATP-dependent proteases, mitochondrial

YDL104c QRI7 similarity to H. influenzaesialoglycoprotease (gcp)

YDR415c strong similarity to bacterial leucylaminopeptidase

Transport facilitationion channels

YGR217w CCH1 calcium channel proteinYLL052c member of mip family transmembrane

channelsYJL093c TOK1 outward-rectifier potassium channelYPR192w similarity to plasma membrane and water

channel proteinsYLL053c similarity to water channel proteinsYIL114c POR2 voltage-dependent anion channel

(YVDAC2)YJR040w GEF1 voltage-gated chloride channel protein

ion transporters

YNR055c HOL1 member of major facilitator superfamilymultidrug-resistance protein subfamily 1

YIL048w similarity to amino-phospholipids-ATPaseDrs2p

mmeettaall iioonn ttrraannssppoorrtteerrss ((CCuu,, FFee,, eettcc..))YOR316c COT1 cobalt accumulation proteinYPR124w CTR1 copper transport proteinYHR175w CTR2 copper transport proteinYLR411w CTR3 copper transport protein YGL255w ZRT1 high-affinity zinc transport proteinYLR130c ZRT2 low-affininty zinc transporterYMR319c FET4 low-affinity Fe(II) iron transport proteinYOL122c SMF1 manganese transporterYBR290w BSD2 metal homeostasis proteinYDR270w CCC2 probable copper-transporting ATPaseYBR295w PCA1 P-type Cu2+-transporting ATPaseYMR243c ZRC1 zinc- and cadmium resistance protein

ootthheerr ccaattiioonn ttrraannssppoorrtteerrss ((NNaa,, KK,, CCaa,, NNHH44,, eettcc..))YGR121c MEP1 ammonia permease of high capacity and

moderate affinityYDL128w VCX1 Ca2+-transport (H+/Ca2+ exchange) protein,

vacuolarYGL006w PMC1 Ca2+-transporting P-type ATPaseYGL167c PMR1 Ca2+-transporting P-type ATPaseYCR024c-a PMP1 H+-ATPase subunit, plasma membraneYEL017c-a PMP2 H+-ATPase subunit, plasma membraneYMR054w STV1 H+-ATPase V0 domain 102K subunit,


vacuolar


gazetteer

YEL027w CUP5 H+-ATPase V0 domain 17K subunit,vacuolar

YPL234c TFP3 H+-ATPase V0 domain 17K subunit,vacuolar

YLR447c VMA6 H+-ATPase V0 domain 36K subunit,vacuolar

YOR270c VPH1 H+-ATPase V0 domain 95K subunit,vacuolar

YGR020c VMA7 H+-ATPase V1 domain 14K subunit,vacuolar

YOR332w VMA4 H+-ATPase V1 domain 27K subunit,vacuolar

YEL051w VMA8 H+-ATPase V1 domain 32K subunit,vacuolar

YKL080w VMA5 H+-ATPase V1 domain 42K subunit,vacuolar

YPR036w VMA13 H+-ATPase V1 domain 54K subunit,vacuolar

YBR127c VMA2 H+-ATPase V1 domain 60K subunit,vacuolar

YDL185w TFP1 H+-ATPase V1 domain 69K subunit,vacuolar

YGL008c PMA1 H+-transporting P-type ATPaseYPL036w PMA2 H+-transporting P-type ATPase 2YNL142w MEP2 high-affinity low-capacity ammonia

permeaseYJL129c TRK1 high-affinity potassium transport proteinYAL026c DRS2 membrane-spanning P-type amino-

phospholipids-ATPaseYKR050w TRK2 moderate-affinity potassium transport

proteinYHR026w PPA1 proteolipid protein of proton-transporting

ATPaseYEL031w SPF1 P-type ATPaseYLR138w NHA1 putative Na+/H+ antiporterYBR235w similarity to bumetanide-sensitive Na+-K+-


NapAYDR456w similarity to Na+/H+ antiportersYPR138c MEP3 strong similarity to ammonium transport

proteinsYHL016c DUR3 urea transport protein

aanniioonn ttrraannssppoorrtteerrss ((CCll,, SSOO44 ,,PPOO44,, eettcc))YLR348c dicarboxylate carrier proteinYML123c PHO84 high-affinity inorganic phosphate/H+

symporterYBR294w SUL1 high-affinity sulphate transport proteinYJL117w PHO86 inorganic phospate transporterYCR037c PHO87 member of the phosphate permease

familyYJR077c MIR1 phosphate transport protein,

mitochondrial (MCF)YBR235w similarity to bumetanide-sensitive Na+-K+-


NapAYNR013c similarity to membrane protein Pho87p

and hypothetical protein YJL198wYCR098c GIT1 similarity to phosphate transporter

proteinsYPR003c similarity to sulphate transporter proteinsYER053c strong similarity to mitochondrial


phosphate permeaseYLR092w SEL2 strong similarity to Sul1p

sugar and carbohydrate transporters

YPR021c similarity to human citrate transporterprotein

YKL217w JEN1 carboxylic-acid transporter proteinYBR291c CTP1 citrate transport protein, mitochondrial

(MCF)YLR348c dicarboxylate carrier proteinYLR081w GAL2 galactose (and glucose) permeaseYGR289c AGT1 general α-glucoside permeaseYLL043w FPS1 glycerol channel proteinYNL318c HXT14 hexose transport proteinYJL214w HXT8 hexose transport proteinYJL219w HXT9 hexose transport proteinYFL011w HXT10 hexose transporterYDL194w SNF3 high-affinity glucose transporterYEL069c HXT13 high-affinity hexose transporterYMR011w HXT2 high-affinity hexose transporterYDR343c HXT6 high-affinity hexose transporterYDR342c HXT7 high-affinity hexose transporterYML123c PHO84 high-affinity inorganic phosphate/H+

symporterYOL156w HXT11 low-affinity glucose transporterYHR094c HXT1 low-affinity hexose transporterYDR345c HXT3 low-affinity hexose transporterYDR497c ITR1 major myo-inositol permeaseYBR298c MAL31 maltose permeaseYDL198c YHM1 member of the mitochondrial carrier

family (MCF)YHR092c HXT4 moderate- to low-affinity glucose

transporterYOL103w ITR2 myo-inositol transport proteinYBR241c similarity to glucose transport proteinsYGL104c similarity to glucose transport proteinsYDR387c similarity to Itr1p and Itr2pYFR045w similarity to mitochondrial citrate transport

proteins

YCR098c GIT1 similarity to phosphate transporterproteins

YDL199c similarity to sugar transporter proteinsYFL040w similarity to yeast glucose transport

proteinsYHR096c HXT5 strong similarity to hexose transportersYDL245c HXT15 strong similarity to Hxt17p and Haxt7pYJR160c strong similarity to Mal3TpYDR536w STL1 strong similarity to members of the sugar

permease familyYOR271c strong similarity to Rattus tricarboxylate

carrierYDL247w strong similarity to sugar transport

proteinsYIL171w strong similarity to sugar transport



proteinsYNR072w HXT17 sugar transport proteinYDL138w RGT2 suppressor of snf3 mutant

amino-acid transporters

YBR068c BAP2 amino-acid permeaseYEL063c CAN1 amino-acid permeaseYBR069c VAP1 amino-acid permeaseYCL025c AGP1 asparagine and glutamine permeaseYGL077c HNM1 choline permeaseYPL265w DIP5 dicarboxylic amino-acid permeaseYDL210w UGA4 GABA-specific high-affinity permeaseYKR039w GAP1 general amino-acid permeaseYDR508c GNP1 high-affinity glutamine permeaseYGR055w MUP1 high-affinity methionine permeaseYNL270c ALP1 high-affinity permease for basic amino

acidsYOL020w SCM2 high-affinity tryptophan transport proteinYGR191w HIP1 histidine permeaseYNL268w LYP1 lysine-specific high-affinity permeaseYOR130c ARG11 member of the mitochondrial carrier

family (MCF)YHL036w MUP3 methionine permeaseYOR348c PUT4 proline and γ-aminobutyrate permeaseYKL174c similarity to choline transport protein


Ctr1pYFL055w similarity to Gap1p and other amino-acid

permeasesYDR160w similarity to lysine transport protein LYP1YLL061w strong similarity to amino-acid transport

protein Gap1pYDR046c (PAP1) strong similarity to amino-acid transport

proteinsYBR132c strong similarity to amino-acid permeasesYPL274w strong similarity to amino-acid transport

proteins

lipid transporters

YBR041w FAT1 fatty-acid transporterYKL188c PAT1 long-chain-fatty-acid transporterYPL147w PXA1 long-chain-fatty-acid transporterYKL174c similarity to choline transport protein


Ctr1pYHR123w EPT1 sn-1,2-diacylglycerol ethanolamine- and

cholinephosphotransferase

purine and pyrimidine transporters

YMR056c AAC1 ADP/ATP carrier protein (MCF)YBL030c AAC2 ADP/ATP carrier protein (MCF)YBR085w AAC3 ADP/ATP carrier protein (MCF)YBR192w RIM2 mitochondrial carrier protein (MCF)YER056c FCY2 purine-cytosine permeaseYER060w FCY21 purine-cytosine permeaseYOR222w similarity to ADP/ATP carrier proteinsYPL134c similarity to ADP/ATP carrier proteinsYPR011c similarity to ADP/ATP carrier proteins and

Graves disease carrier proteinYOR071c similarity to allantoin or uracil transport

proteinsYOR192c similarity to allantoin or uracil transport

proteinsYGR096w similarity to bovine Graves disease carrier

proteinYHR002w similarity to bovine mitochondrial carrier

protein/Grave’s disease carrier proteinYGL186c similarity to hypothetical protein YER060w

and weak similarity to FCY2 proteinYBL042c strong similarity to allantoin and uracil

transport proteinsYER060w-a FCY22 strong similarity to Fcy2pYBR021w FUR4 uracil permease

allantoin and allantoate transporters

YJR152w DAL5 allantoate permeaseYIR028w DAL4 allantoin permeaseYIL166c similarity to allantoate permease Dal5pYCR028c FEN2 similarity to allantoate permease

transporterYGR260w similarity to allantoate transport proteinYLR004c similarity to allantoate transport protein

YOR071c similarity to allantoin or uracil transportproteins

YOR192c similarity to allantoin or uracil transportproteins

YLR237w similarity to allantoin transport proteinYLL055w similarity to Dal5pYBL042c strong similarity to allantoin and uracil

transport proteinsYAL067c SEO1 suppressor of sulphoxyde ethionine

resistance

transport ATPases

YGL006w PMC1 Ca2+-transporting P-type ATPaseYGL167c PMR1 Ca2+-transporting P-type ATPaseYKL016c ATP7 F1F0-ATPase complex, F0 D subunitYBL099w ATP1 F1F0-ATPase complex, F1 α subunitYJR121w ATP2 F1F0-ATPase complex, F1 β subunitYDL004w ATP16 F1F0-ATPase complex, F1 δ subunitYPL078c ATP4 F1F0-ATPase complex, F1 δ subunitYPL271w ATP15 F1F0-ATPase complex, F1 ε subunitYBR039w ATP3 F1F0-ATPase complex, F1 γ subunitYDR298c ATP5 F1F0-ATPase complex, OSCP subunitYLR295c ATP14 F1F0-ATPase complex, subunit hYCR024c-a PMP1 H+-ATPase subunit, plasma membraneYEL017c-a PMP2 H+-ATPase subunit, plasma membraneYMR054w STV1 H+-ATPase V0 domain 102K subunit,













vacuolar YGL008c PMA1 H+-transporting P-type ATPaseYPL036w PMA2 H+-transporting P-type ATPase 2YAL026c DRS2 membrane-spanning P-type amino-

phospholipids-ATPaseYDR270w CCC2 probable copper-transporting ATPaseYHR026w PPA1 proteolipid protein of proton-transporting

ATPaseYEL031w SPF1 P-type ATPaseYDR040c ENA1 P-type ATPase involved in Na+ and Li+

effluxYDR039c ENA2 P-type ATPase involved in Na+ effluxYDR038c ENA5 P-type ATPase involved in Na+ effluxYBR295w PCA1 P-type Cu2+-transporting ATPaseYIL048w similarity to amino-phospholipids-ATPase

Drs2pYER166w similarity to ATPase P. falciparum ATPase

2YMR162c similarity to ATPasesYDR093w similarity to P. falciparum ATPase 2

ABC transporters

YDR406w PDR15 ATP-binding cassette protein familymember

YLR188w MDL1 ATP-binding cassette transporter familymember

YPL270w MDL2 ATP-binding cassette transporter familymember

YKL209c STE6 ATP-binding cassette transporter proteinYGR281w YOR1 ATP-binding cassette transporter protein

required for oligomycin resistanceYMR301c ATM1 ATP-binding cassette transporter protein,

mitochondrialYCR011c ADP1 ATP-dependent permeaseYDR135c YCF1 glutathione S-conjugate transporter,

vacuolarYKL188c PAT1 long-chain-fatty-acid transporterYPL147w PXA1 long-chain-fatty-acid transporterYDR011w SNQ2 multidrug resistance proteinYPL058c PDR12 multidrug resistance transporterYOR153w PDR5 pleiotropic drug resistance proteinYOL075c similarity to A. gambiae ATP-binding-

cassette proteinYER036c similarity to members of the ABC

transporter familyYLL015w similarity to metal resistance proteinsYHL035c similarity to multidrug resistance proteinsYKR103w similarity to multidrug resistance proteinsYKR104w similarity to multidrug resistance proteinsYLL048c similarity to rat organic anion transporterYIL013c PDR11 similarity to Snq2p and other ATP-

dependent permeasesYOR328w PDR10 strong similarity to ABC transporter

proteinsYOR011w strong similarity to ATP-dependent

permeases


gazetteer

YDR091c strong similarity to human RNase Linhibitor and to M. jannaschii ABCtransporter

YNR070w strong similarity to Snq2p

drug transporters

YML116w ATR1 aminotriazole and 4-nitroquinolineresistance protein

YGR281w YOR1 ATP-binding cassette transporter proteinrequired for oligomycin resistance

YGR197c SNG1 involved in nitroguanidine resistanceYEL065w probably multidrug resistance proteinYMR123w PKR1 resistance against Pichia farinosa killer

toxin (SMK toxin) when expressed by amulticopy plasmid

YMR088c similarity multidrug resistance proteinsYDR119w similarity to B. subtilis tetracyclin

resistanceYBR293w similarity to multidrug resistance proteinsYGR138c similarity to multidrug resistance proteinsYHR048w similarity to multidrug resistance proteinsYPR156c similarity to multidrug resistance proteinsYNL065w similarity to resistance proteinsYIL013c PDR11 similarity to Snq2p and other ATP-

dependent permeasesYMR279c strong similarity to aminotriazole

resistance proteinYGR224w strong similarity to drug resistance protein

SGE1YBR052c strong similarity to S. pombe brefeldin A

resistance protein obr1YAL067c SEO1 suppressor of sulphoxyde ethionine

resistance

other transport-facilitators

YFL028c CAF16 ATP-binding cassette transporter proteinfamily member

YER019c-a SEB2 ER protein-translocation complex subunitYLR378c SEC61 ER protein-translocation complex subunitYPL094c SEC62 ER protein-translocation complex subunitYOR254c SEC63 ER protein-translocation complex subunitYBR171w SEC66 ER protein-translocation complex subunitYLR292c SEC72 ER protein-translocation complex subunitYDR086c SSS1 ER protein-translocation complex subunitYIL134w FLX1 FAD carrier protein, mitochondrial (MCF)YCR023c member of major facilitator superfamily

multidrug-resistance protein family 2YKL039w PTM1 member of the major facilitator

superfamilyYPR058w YMC1 mitochondrial carrier protein (MCF)YNR017w MAS6 mitochondrial inner membrane import



translocase subunitYNL131w TOM22 mitochondrial outer membrane import






receptor subunit, 7KYNL055c POR1 mitochondrial outer membrane porinYNL121c TOM70 mitochondrial outer membrane

specialized import receptorYAR035w YAT1 outer carnitine acetyltransferase,

mitochondrialYKR093w PTR2 peptide transporterYIL120w similarity to antibiotic resistance proteinsYIL121w similarity to antibiotic resistance proteinsYCL038c similarity to bacterial membrane

transporterYBR043c similarity to benomyl/methotrexate

resistance proteinYHL040c similarity to C. carbonum toxin pumpYHL047c similarity to C. carbonum toxin pumpYER024w similarity to carnitine O-acetyltransferase

Yat1pYOR291w similarity to cation translocating ATPasesYFL054c similarity to channel proteinsYBR180w similarity to drug resistance proteinsYIL006w similarity to Flx1pYOR306c similarity to human X-linked PEST-

containing transporterYIL056w similarity to hypothetical protein YER064cYNL003c PET8 similarity to mitochondrial rat

tricarboxylate transport protein YOL119c similarity to monocarboxylate transporter

proteinsYGR065c similarity to P. putida phthalate transporterYOL163w similarity to P. putida phthalate transporterYEL006w similarity to peroxisomal membrane and

mitochondrial carrier proteinsYJR124c similarity to Staphylococcus multidrug

resistance proteinYNL125c similarity to YKL221w and human X-linked

PEST-containing transporterYBR008c strong similarity to benomyl/methotrexate

resistance protein

YCL069w strong similarity to drug resistance proteinSGE1

YER087c-a SEB1 strong similarity to mammalian Sec61βsubunit

YKR067w strong similarity to Sct1pYBL011w SCT1 suppresses a choline-transport mutantYBL089w weak similarity to A. thaliana aminoacid

permease AAP3YIL088c weak similarity to A. thaliana aminoacid

permease AAP4YJR001w weak similarity to A. thaliana aminoacid

permease AAP4YER119c weak similarity to E. herbicola tyrosine

permeaseYKL221w weak similarity to human X-linked PEST-

containing transporterYEL064c weak similarity to members of the major

facilitator superfamilyYJR106w weak similarity to Na+/H+ antiporterYDL206w weak similarity to transporter proteinsYKL146w weak similarity to transporter proteins

Intracellular transportnuclear transport

YIL075c SEN3 26S proteasome regulatory subunitYOR048c RAT1 5’-3’ exoribonucleaseYGL097w SRM1 GDP/GTP exchange factor for

Gsp1p/Gsp2pYOR185c GSP2 GTP-binding proteinYLR293c GSP1 GTP-binding protein of the RAS

superfamilyYAL005c SSA1 heat-shock protein of HSP70 familyYOR160w MTR10 involved in mRNA transportYJL050w MTR4 involved in nucleocytoplasmic transport of

mRNAYBR017c KAP104 karyopherinYNL189w SRP1 karyopherin-α or importinYLR347c KAP95 karyopherin-βYKL186c MTR2 mRNA transport proteinYPL124w NIP29 nuclear import proteinYPL174c NIP80 nuclear import proteinYMR129w POM152 nuclear pore membrane glycoproteinYFR002w NIC96 nuclear pore proteinYJL041w NSP1 nuclear pore proteinYOR098c NUP1 nuclear pore proteinYKL068w NUP100 nuclear pore proteinYMR047c NUP116 nuclear pore proteinYKL057c NUP120 nuclear pore proteinYKR082w NUP133 nuclear pore proteinYGL092w NUP145 nuclear pore proteinYER105c NUP157 nuclear pore proteinYIL115c NUP159 nuclear pore proteinYBL079w NUP170 nuclear pore proteinYML103c NUP188 nuclear pore proteinYLR335w NUP2 nuclear pore proteinYDR192c NUP42 nuclear pore proteinYGL172w NUP49 nuclear pore proteinYGR119c NUP57 nuclear pore proteinYJL061w NUP82 nuclear pore proteinYDL116w NUP84 nuclear pore proteinYJR042w NUP85 nuclear pore proteinYGL100w SEH1 nuclear pore proteinYBR170c NPL4 nuclear protein localization factor and ER

translocation componentYER009w NTF2 nuclear transport factorYDR432w NPL3 nucleolar proteinYDR002w YRB1 ran-specific GTPase-activating proteinYER107c GLE2 required for nuclear pore complex

structure and functionYIR011c STS1 required for transport of Rna15p from the

cytoplasm to the nucleusYDL207w GLE1 RNA export mediatorYIL063c YRB2 similarity to Yrp1p and Nup2pYLR119w SRN2 suppressor of rna1-1 mutationYFL049w weak similarity to Npl6p

mitochondrial transport

YMR056c AAC1 ADP/ATP carrier protein (MCF)YBL030c AAC2 ADP/ATP carrier protein (MCF)YBR085w AAC3 ADP/ATP carrier protein (MCF)YMR301c ATM1 ATP-binding cassette transporter protein,

mitochondrialYML042w CAT2 carnitine O-acetyltransferaseYBR291c CTP1 citrate transport protein, mitochondrial

(MCF)YOR316c COT1 cobalt accumulation proteinYOR037w CYC2 cytochrome c mitochondrial import factorYLR348c dicarboxylate carrier proteinYKL016c ATP7 F1F0-ATPase complex, F0 D subunitYBL099w ATP1 F1F0-ATPase complex, F1 α subunitYJR121w ATP2 F1F0-ATPase complex, F1 β subunitYDL004w ATP16 F1F0-ATPase complex, F1 δ subunitYPL078c ATP4 F1F0-ATPase complex, F1 δ subunitYPL271w ATP15 F1F0-ATPase complex, F1 ε subunitYBR039w ATP3 F1F0-ATPase complex, F1 γ subunitYDR298c ATP5 F1F0-ATPase complex, OSCP subunitYLR295c ATP14 F1F0-ATPase complex, subunit hYIL134w FLX1 FAD carrier protein, mitochondrial (MCF)YOR232w MGE1 heat-shock protein - chaperoneYLL024c SSA2 heat-shock protein of HSP70 family,

cytosolicYGR028w MSP1 intra-mitochondrial sorting protein

YOR130c ARG11 member of the mitochondrial carrierfamily (MCF)

YDL198c YHM1 member of the mitochondrial carrierfamily (MCF)

YNL064c YDJ1 mitochondrial and ER import proteinYBR192w RIM2 mitochondrial carrier protein (MCF)YPR058w YMC1 mitochondrial carrier protein (MCF)YBR104w YMC2 mitochondrial carrier protein (MCF)YML062c MFT1 mitochondrial fusion target proteinYNR017w MAS6 mitochondrial inner membrane import



translocase subunitYNL131w TOM22 mitochondrial outer membrane import






receptor subunit, 7KYNL055c POR1 mitochondrial outer membrane porinYNL121c TOM70 mitochondrial outer membrane

specialized import receptorYAR035w YAT1 outer carnitine acetyltransferase,

mitochondrialYJR077c MIR1 phosphate transport protein,

mitochondrial (MCF)YBR091c MRS5 regulator of mitochondrial intron splicingYPL134c similarity to ADP/ATP carrier proteinsYER024w similarity to carnitine O-acetyltransferase

Yat1pYPR021c similarity to human citrate transporter

proteinYER053c strong similarity to mitochondrial

phosphate carrier proteinYLR034c strong similarity to SMF2 proteinYHR117w TOM71 strong similarity to Tom70p/Mas70pYHR050w SMF2 suppressor of mitochondrial matrix

mutantYIL114c POR2 voltage dependent anion channel

(YVDAC2)

vesicular transport (Golgi network, etc.)

YBR164c ARL1 ADP-ribosylation factorYOR094w ARF3 ADP-ribosylation factor 3YGL167c PMR1 Ca2+-transporting P-type ATPaseYGR167w CLC1 clathrin light chainYOL062c APM4 clathrin-associate protein YAP54YPL259c APM1 clathrin-associated proteinYBR288c APM3 clathrin-associated protein complex,

medium subunitYPL010w RET3 coatomer complex ζ subunitYDL145c RET1 coatomer complex α subunit of secretory

pathway vesiclesYGL137w SEC27 coatomer complex β‘ subunit (β‘-cop) of

secretory pathway vesiclesYDR238c SEC26 coatomer complex β subunit of secretory

pathway vesiclesYFR051c RET2 coatomer complex δ subunitYNL287w SEC21 coatomer complex γ subunit (γ-COP) of

secretory pathway vesiclesYDR170c SEC7 component of non-clathrin vesicle coatYPR181c SEC23 component of the COPII coat of ER-Golgi

vesiclesYDL195w SEC31 component of the COPII coat of ER-Golgi

vesiclesYGL200c EMP24 component of the COPII-coated vesicles,

24KYML012w ERV25 component of the COPII-coated vesicles,

25KYMR017w DBI9 Dbf2p interacting proteinYKR054c DYN1 dynein heavy chain, cytosolicYLR083c EMP70 endosomal proteinYBL040c ERD2 ER lumen protein-retaining receptorYJR031c GEA1 GDP/GTP exchange factor for ARFYEL022w GEA2 GDP/GTP exchange factor for ARFYNR026c SEC12 GDP/GTP exchange factor for Sar1pYPR017c DSS4 GDP/GTP exchange factor for Sec4pYDL192w ARF1 GTP-binding protein of the ARF familyYDL137w ARF2 GTP-binding protein of the ARF familyYPL218w SAR1 GTP-binding protein of the ARF familyYFL038c YPT1 GTP-binding protein of the RAB familyYER031c YPT31 GTP-binding protein of the RAB familyYLR262c YPT6 GTP-binding protein of the RAB familyYML001w YPT7 GTP-binding protein of the RAB familyYFL005w SEC4 GTP-binding protein of the RAS

superfamilyYLL024c SSA2 heat-shock protein of HSP70 family,

cytosolicYLR268w SEC22 high copy suppressor of ypt1 null

mutationYDR189w SLY1 hydrophilic suppressor of ypt1 and

member of the Sec1p familyYDL058w USO1 intracellular protein transport proteinYPL145c KES1 involved in ergosterol biosynthesisYKR068c BET3 involved in targeting and fusion of ER to

Golgi transport vesiclesYMR183c SSO2 involved in vesicle transport from Golgi to

plasma membraneYNL064c YDJ1 mitochondrial and ER import protein


gazetteer

YJL004c SYS1 multicopy suppressor of ypt6YPL085w SEC16 multidomain vesicle coat proteinYOR326w MYO2 myosin heavy chainYFL025c BST1 negative regulator of COPII vesicle

formationYMR079w SEC14 phosphatidylinositol/phosphatidylcholine

transfer proteinYCR067c SED4 protein of the endoplasmic reticulumYIL004c BET1 protein transport proteinYLR208w SEC13 protein transport proteinYNL272c SEC2 protein transport proteinYGR009c SEC9 protein transport proteinYGL145w TIP20 required for ER to Golgi transportYDR498c SEC20 secretory pathway proteinYBR097w VPS15 ser/thr protein kinaseYBR264c similarity to GTP-binding proteinsYKL196c similarity to Sec22pYJL193w similarity to Sly41pYGL210w YPT32 small GTP-binding proteinYKL006c-a SFT1 SNARE-like proteinYPL051w strong similarity to ADP-ribosylation

factorsYDR107c strong similarity to EMP70 proteinYAL030w SNC1 strong similarity to synaptic vesicle-

associated membrane proteinYOR327c SNC2 strong similarity to synaptobrevinYER039c strong similarity to vanadate resistance

protein Van2pYLR026c SED5 syntaxin (T-SNARE)YOR075w UFE1 syntaxin (T-SNARE) of the ERYPL232w SSO1 syntaxin-related proteinYBL050w SEC17 transport vesicle fusion proteinYLR396c VPS33 vacuolar sorting proteinYML097c VPS9 vacuolar sorting proteinYGL225w GOG5 vanadate-resistance proteinYGL233w SEC15 vesicular traffic control proteinYBR080c SEC18 vesicular-fusion protein, functional

homologue of NSFYLR093c weak similarity to synaptobrevinYLR078c BOS1 weak similarity to synaptobrevin

(V-SNARE)

peroxisomal transport

YML042w CAT2 carnitine O-acetyltransferaseYKL188c PAT1 long-chain-fatty-acid transporterYPL147w PXA1 long-chain-fatty-acid transporterYER015w FAA2 long-chain-fatty-acid-CoA ligaseYDR329c PAS3 peroxisomal assembly proteinYJL210w PAS5 peroxisomal assembly proteinYDR142c PAS7 peroxisomal import proteinYLR191w PAS20 peroxisomal protein involved in protein

importYDR244w PAS10 putative peroxisomal targeting signal

receptor

vacuolar transport

YDL128w VCX1 Ca2+-transport (H+/Ca2+ exchange) protein,vacuolar

YGL006w PMC1 Ca2+-transporting P-type ATPaseYDR135c YCF1 glutathione S-conjugate transporter,

vacuolarYOR089c VPS21 GTP-binding proteinYER031c YPT31 GTP-binding protein of the RAB familyYKR014c YPT52 GTP-binding protein of the RAB familyYNL093w YPT53 GTP-binding protein of the RAB family

(RAS superfamily)YMR054w STV1 H+-ATPase V0 domain 102K subunit,













vacuolar YPL066w VPS28 involved in vacuolar trafficYMR004w MVP1 required for vacuolar protein sortingYBR097w VPS15 ser/thr protein kinaseYJL222w strong similarity to Pep1pYOR036w PEP12 syntaxin (T-SNARE)YNR006w VPS27 vacuolar protein sorting-associated

proteinYGL095c VPS45 vacuolar protein sorting-associated

proteinYDR323c PEP7 vacuolar segregation proteinYPL045w VPS16 vacuolar sorting proteinYPR173c VPS4 vacuolar sorting proteinYAL002w VPS8 vacuolar sorting proteinYML097c VPS9 vacuolar sorting protein

extracellular transport

YJL085w EXO70 70K exocyst component proteinYDR129c SAC6 actin filament bundling protein, fimbrinYKL209c STE6 ATP-binding cassette transporter proteinYDL226c GCS1 cell proliferation zinc-finger proteinYER136w GDI1 GDP dissociation inhibitorYLL043w FPS1 glycerol channel proteinYJL044c GYP6 GTPase-activating proteinYLR262c YPT6 GTP-binding protein of the RAB familyYJL205c-a NCE1 involved in non-classical protein export

pathwayYPR149w NCE2 involved in non-classical protein export

pathwayYNL036w NCE3 involved in non-classical protein export

pathwayYOR326w MYO2 myosin heavy chainYJL093c TOK1 outward-rectifier potassium channelYMR308c PSE1 protein secretion enhancerYDR164c SEC1 protein transport proteinYNL272c SEC2 protein transport proteinYIL068c SEC6 protein transport proteinYPR055w SEC8 protein transport proteinYGR009c SEC9 protein transport proteinYKL212w SAC1 recessive suppressor of secretory defectYLR166c SEC10 required for exocytosisYDR166c SEC5 required for exocytosisYNR049c MSO1 secretion protein, multicopy suppressor of

sec1YER008c SEC3 secretory pathway proteinYOR307c SLY41 secretory pathway proteinYBR162w-a YSY6 secretory pathway proteinYLR250w SSP120 secretory proteinYCR032w similarity to human CDC4L proteinYER006w similarity to P. polycephalum myosin-

related protein mlpAYGR131w strong similarity to Nce2pYNL325c suppressor of sac1 mutationYPL232w SSO1 syntaxin-related proteinYGL233w SEC15 vesicular traffic control proteinYBR080c SEC18 vesicular-fusion protein, functional

homologue of NSF

cellular import

YPL195w YKS4 α- or γ- adaptin, large subunit of theclathrin-associated protein(AP) complex

YBL037w APL3 α-adaptin, large subunit of the clathrin-associated protein(AP) complex

YFL039c ACT1 actinYDR129c SAC6 actin filament bundling protein, fimbrinYDL029w ACT2 actin-like proteinYCL040w GLK1 aldohexose specific glucokinaseYJR152w DAL5 allantoate permeaseYIR028w DAL4 allantoin permeaseYBR068c BAP2 amino-acid permeaseYEL063c CAN1 amino-acid permeaseYBR069c VAP1 amino-acid permeaseYGR121c MEP1 ammonia permease of high capacity and

moderate affinityYKL135c APL2 β-adaptinYGR261c YKS5 β-adaptin, large subunit of the clathrin-

associated protein(AP) complexYBR109c CMD1 calmodulinYDL226c GCS1 cell proliferation zinc-finger proteinYMR058w FET3 cell-surface ferroxidaseYGL077c HNM1 choline permeaseYGL206c CHC1 clathrin heavy chainYGR167w CLC1 clathrin light chainYLR170c APS1 clathrin-associated protein (AP) complex,

small subunit AP19YJR058c APS2 clathrin-associated protein 17, small

subunitYJR005w YAP80 clathrin-associated protein complex,

β subunitYJL024c APS3 clathrin-associated protein(AP) complex,

small subunitYPR124w CTR1 copper transport proteinYHR175w CTR2 copper transport proteinYNL243w SLA2 cytoskeleton assembly control proteinYLL001w DNM1 dynamin-related proteinYDL210w UGA4 GABA-specific high-affinity permeaseYPR029c APL4 γ-adaptin, large subunit of the clathrin-

associated protein(AP) complexYLR081w GAL2 galactose (and glucose) permeaseYNR026c SEC12 GDP/GTP exchange factor for Sar1pYKR039w GAP1 general amino-acid permeaseYLL043w FPS1 glycerol channel proteinYOR089c VPS21 GTP-binding proteinYER031c YPT31 GTP-binding protein of the RAB familyYKR014c YPT52 GTP-binding protein of the RAB familyYML001w YPT7 GTP-binding protein of the RAB familyYNL093w YPT53 GTP-binding protein of the RAB family

(RAS superfamily)YNL318c HXT14 hexose transport proteinYJL214w HXT8 hexose transport proteinYJL219w HXT9 hexose transport proteinYFL011w HXT10 hexose transporterYDL194w SNF3 high-affinity glucose transporterYEL069c HXT13 high-affinity hexose transporterYMR011w HXT2 high-affinity hexose transporterYDR343c HXT6 high-affinity hexose transporterYDR342c HXT7 high-affinity hexose transporterYML123c PHO84 high-affinity inorganic phosphate/H+

symporterYNL142w MEP2 high-affinity low capacity ammonia

permeaseYGR055w MUP1 high-affinity methionine permease

YNL270c ALP1 high-affinity permease for basic aminoacids

YJL129c TRK1 high-affinity potassium transport proteinYBR294w SUL1 high-affinity sulphate transport proteinYOL020w SCM2 high-affinity tryptophan transport proteinYGR191w HIP1 histidine permeaseYMR319c FET4 low-affinity Fe(II) iron transport proteinYOL156w HXT11 low-affinity glucose transporterYHR094c HXT1 low-affinity hexose transporterYDR345c HXT3 low-affinity hexose transporterYNL268w LYP1 lysine-specific high-affinity permeaseYDR497c ITR1 major myo-inositol permeaseYBR298c MAL31 maltose permeaseYOL122c SMF1 manganese transporterYKR050w TRK2 moderate-affinity potassium transport

proteinYHR092c HXT4 moderate to low-affinity glucose

transporterYOL103w ITR2 myo-inositol transport proteinYLR240w VPS34 phosphatidylinositol 3-kinaseYOR348c PUT4 proline and γ-aminobutyrate permeaseYER056c FCY2 purine-cytosine permeaseYLR088w GAA1 required for attachment of GPI anchor

onto proteinsYNL084c END3 required for endocytosis and cytoskeletal

organizationYJR090c GRR1 required for glucose repression and for

glucose and cation transportYCR009c RVS161 similarity to human amphiphysin and

Rvs167pYDR046c (PAP1) strong similarity to amino-acid transport

proteinsYHR096c HXT5 strong similarity to hexose transportersYIL170w HXT12 strong similarity to sugar transport


proteinsYNR072w HXT17 sugar transport proteinYOR329c SCD5 suppressor of clathrin deficiencyYPR129w SCD6 suppressor of clathrin deficiencyYBR021w FUR4 uracil permeaseYMR231w PEP5 vacuolar biogenesis proteinYLR337w VRP1 verprolinYBR080c SEC18 vesicular-fusion protein, functional

homologue of NSFYJR040w GEF1 voltage-gated chloride channel proteinYMR243c ZRC1 zinc- and cadmium resistance protein

other intracellular-transport activities

YKR054c DYN1 dynein heavy chain, cytosolicYER019c-a SEB2 ER protein-translocation complex subunitYLR378c SEC61 ER protein-translocation complex subunitYPL094c SEC62 ER protein-translocation complex subunitYOR254c SEC63 ER protein-translocation complex subunitYBR171w SEC66 ER protein-translocation complex subunitYLR292c SEC72 ER protein-translocation complex subunitYDR086c SSS1 ER protein-translocation complex subunitYCR075c ERS1 intracellular protein transport proteinYHL019c APM2 involved in clathrin-dependent transport

processesYJL034w KAR2 nuclear fusion proteinYBR170c NPL4 nuclear protein localization factor and ER

translocation componentYKR093w PTR2 peptide transporterYKL198c PTK1 polyamine transport enhancing proteinYDR040c ENA1 P-type ATPase involved in Na+ and Li+

effluxYER060w FCY21 purine-cytosine permeaseYNL183c NPR1 ser/thr protein kinaseYOR100c similarity to mitochondrial carrier protein

YMC1YGL216w similarity to mouse kinesin-related protein

KIF3YPR009w similarity to sterol uptake protein Sut1pYHR123w EPT1 sn-1,2-diacylglycerol ethanolamine- and

cholinephosphotransferaseYER060w-a FCY22 strong similarity to Fcy2pYER087c-a SEB1 strong similarity to mammalian Sec61β

subunit

Cellular organization andbiogenesis organization and biogenesis of cell wall andplasma membrane

YLR342w FKS1 1,3-—D-glucan synthase, catalytic subunit YGR032w GSC2 1,3-—D-glucan synthase, subunitYOR362c PRE10 26S proteasome subunit C1YJR004c SAG1 α-agglutininYNR044w AGA1 α-agglutinin anchor subunitYGL032c AGA2 α-agglutinin binding subunitYDR077w SED1 abundant cell-surface glycoproteinYJL005w CYR1 adenylate cyclaseYCL007c CWH36 affects the mannoprotein layer of the cell

wallYOR335c ALA1 alanyl-tRNA synthetase, cytosolicYPL061w ALD6 aldehyde dehydrogenase, cytosolicYJR152w DAL5 allantoate permeaseYIR028w DAL4 allantoin permeaseYBR068c BAP2 amino-acid permeaseYEL063c CAN1 amino-acid permeaseYBR069c VAP1 amino-acid permease


gazetteer

YML116w ATR1 aminotriazole and 4-nitroquinolineresistance protein

YGR121c MEP1 ammonia permease of high capacity andmoderate affinity

YDR144c MKC7 aspartyl protease of the periplasmicspace

YLR120c YAP3 aspergillopepsinYKL209c STE6 ATP-binding cassette transporter proteinYGR281w YOR1 ATP-binding cassette transporter protein

required for oligomycin resistanceYCR011c ADP1 ATP-dependent permeaseYER123w YCK3 casein kinase, isoform 3YCL027w FUS1 cell fusion proteinYMR058w FET3 cell-surface ferroxidaseYKL096w CWP1 cell-wall mannoproteinYKL096w-a CWP2 cell-wall mannoproteinYNL322c KRE1 cell-wall proteinYAR050w FLO1 cell-wall protein involved in flocculationYNL192w CHS1 chitin synthase IYBR038w CHS2 chitin synthase IIYBR023c CHS3 chitin synthase IIIYGL077c HNM1 choline permeaseYOR010c TIR2 cold-shock induced proteinYER011w TIR1 cold-shock induced protein of the Tir1p,

Tip1p familyYPR124w CTR1 copper transport proteinYGR282c BGL2 endo-1,3-—glucanase of the cell wallYOR190w SPR1 exo-1,3-—glucanase YDR261c EXG2 exo-1,3-—glucanase minor isoformYLR214w FRE1 ferric (and cupric) reductaseYKL220c FRE2 ferric (and cupric) reductaseYDL210w UGA4 GABA-specific high-affinity permeaseYLR081w GAL2 galactose (and glucose) permeaseYLL016w SDC25 GDP/GTP exchange factorYLR310c CDC25 GDP/GTP exchange factor for Ras1p and

Ras2pYCR038c BUD5 GDP/GTP exchange factor for

Rsr1p/Bud1pYKR039w GAP1 general amino-acid permeaseYMR307w GAS1 glycophospholipid-anchored surface

glycoproteinYOL081w IRA2 GTPase-activating protein for RAS

proteinsYOR101w RAS1 GTP-binding proteinYNL098c RAS2 GTP-binding proteinYHR005c GPA1 GTP-binding protein α subunit of the



pheromone pathwayYLR229c CDC42 GTP-binding protein of RAS superfamilyYCR024c-a PMP1 H+-ATPase subunit, plasma membraneYEL017c-a PMP2 H+-ATPase subunit, plasma membraneYGL008c PMA1 H+-transporting P-type ATPaseYPL036w PMA2 H+-transporting P-type ATPase 2YDR420w HKR1 Hansenula MrakII k9 killer toxin-resistance

proteinYLL024c SSA2 heat-shock protein of HSP70 family,

cytosolicYNL318c HXT14 hexose transport proteinYJL214w HXT8 hexose transport proteinYJL219w HXT9 hexose transport proteinYFL011w HXT10 hexose transporterYDL194w SNF3 high-affinity glucose transporterYEL069c HXT13 high-affinity hexose transporterYMR011w HXT2 high-affinity hexose transporterYDR343c HXT6 high-affinity hexose transporterYDR342c HXT7 high-affinity hexose transporterYML123c PHO84 high-affinity inorganic phosphate/H+

symporterYNL142w MEP2 high-affinity low-capacity ammonia

permeaseYGR055w MUP1 high-affinity methionine permeaseYNL270c ALP1 high-affinity permease for basic amino

acidsYJL129c TRK1 high-affinity potassium transport proteinYBR294w SUL1 high-affinity sulphate transport proteinYOL020w SCM2 high-affinity tryptophan transport proteinYGR191w HIP1 histidine permeaseYBR140c IRA1 inhibitory regulator protein of the RAS-

cyclic AMP pathwayYNL291c MID1 involved in Ca2+ influx during matingYHL019c APM2 involved in clathrin-dependent transport

processesYLR452c SST2 involved in desensitization to α-factor

pheromoneYCL051w LRE1 involved in laminarinase resistanceYER118c SSU81 involved in the HOG1 high-osmolarity

signal transduction pathwayYMR183c SSO2 involved in vesicle transport from Golgi to

plasma membraneYLR155c ASP3A L-asparaginase IIYLR157c ASP3B L-asparaginase IIYLR158c ASP3C L-asparaginase IIYLR160c ASP3D L-asparaginase IIYMR319c FET4 low-affinity Fe(II) iron transport proteinYOL156w HXT11 low-affinity glucose transporterYHR094c HXT1 low-affinity hexose transporterYDR345c HXT3 low-affinity hexose transporterYNL268w LYP1 lysine-specific high-affinity permeaseYDR497c ITR1 major myo-inositol permeaseYBR298c MAL31 maltose permeaseYOL122c SMF1 manganese transporterYIL047c SYG1 member of the major facilitator

superfamilyYKR050w TRK2 moderate-affinity potassium transport

protein

YHR092c HXT4 moderate- to low-affinity glucosetransporter

YGR014w MSB2 multicopy suppressor of a cdc24 budemergence defect

YDR011w SNQ2 multidrug resistance proteinYOL103w ITR2 myo-inositol transport proteinYJL093c TOK1 outward-rectifier potassium channelYKR093w PTR2 peptide transporterYFL026w STE2 pheromone α-factor receptorYKL178c STE3 pheromone a-factor receptorYMR008c PLB1 phospholipase B (lysophospholipase)YOR153w PDR5 pleiotropic drug resistance proteinYCR034w GNS1 probable 1,3-—glucan synthase subunitYOR348c PUT4 proline and γ-aminobutyrate permeaseYPL140c MKK2 protein kinase of the MAP kinase kinase

(MEK) familyYGR009c SEC9 protein transport proteinYER056c FCY2 purine-cytosine permeaseYIL140w SRO4 required for axial pattern of buddingYCR089w FIG2 required for efficient matingYDR122w KIN1 ser/thr protein kinaseYLR096w KIN2 ser/thr protein kinaseYPL176c similarity to chinese hamster transferrin

receptor proteinYKR102w similarity to Flo1pYHL028w similarity to mucin and other ser-thr rich

proteinsYJR151c similarity to mucin proteinsYMR317w similarity to mucins, glucan 1,4-—

glucosidase and exo-—sialidaseYCR098c GIT1 similarity to phosphate transporter

proteinsYIL013c PDR11 similarity to Snq2p and other ATP-

dependent permeasesYIL063c YRB2 similarity to Yrp1p and Nup2pYNL126w SPC98 spindle pole body componentYHR139c SPS100 sporulation-specific wall maturation

proteinYOR328w PDR10 strong similarity to ABC transporter

proteinsYDR046c (PAP1) strong similarity to amino-acid transport

proteinsYDR134c strong similarity to Flo1pYAL063c FLO9 strong similarity to Flo1pYLR343w strong similarity to Gas1p and C. albicans

pH responsive proteinYOL030w strong similarity to glycoprotein GAS1YHR096c HXT5 strong similarity to hexose transportersYDR536w STL1 strong similarity to members of the sugar

permease familyYIL170w HXT12 strong similarity to sugar transport


proteinsYNR072w HXT17 sugar transport proteinYPL232w SSO1 syntaxin-related proteinYBR067c TIP1 temp.shock induced protein of the

Srp1p/Tip1p familyYJR007w SUI2 translation initiation factor eIF2, α subunitYIL147c SLN1 two-component signal transducerYER125w RSP5 ubiquitin-protein ligaseYBR021w FUR4 uracil permeaseYHL016c DUR3 urea transport proteinYGL233w SEC15 vesicular traffic control proteinYJR040w GEF1 voltage-gated chloride channel proteinYMR243c ZRC1 zinc- and cadmium resistance protein

organization and biogenesis of cytoskeleton

YML085c TUB1 α-1 tubulinYML124c TUB3 α-3 tubulinYFL039c ACT1 actinYMR092c AIP1 actin cytoskeleton componentYDR129c SAC6 actin filament bundling protein, fimbrinYDL178w AIP2 actin interacting protein 2YJR065c ACT4 actin-related proteinYCR088w ABP1 actin-binding proteinYDL029w ACT2 actin-like proteinYDR106w ARP10 actin-related proteinYNL059c ARP5 actin-related proteinYLR085c ARP6 actin-related proteinYOR141c ARP8 actin-related proteinYNR033w ARP9 actin-related proteinYNL138w SRV2 adenylate cyclase-associated protein, 70KYAL020c ATS1 α-tubulin suppressorYER016w BIM1 binding to microtubulesYFL037w TUB2 β-tubulinYOR265w RBL2 β-tubulin binding proteinYBR200w BEM1 bud emergence mediatorYLR319c BUD6 bud site selection proteinYNL271c BNI1 budding proteinYBR109c CMD1 calmodulinYCR002c CDC10 cell division control proteinYGL116w CDC20 cell division control proteinYLR314c CDC3 cell division control proteinYFL009w CDC4 cell division control proteinYHR129c ACT5 centractinYLR175w CBF5 centromere/microtubule binding proteinYOR349w CIN1 chromosome segregation proteinYLL050c COF1 cofilin, actin binding and severing proteinYBL007c SLA1 cytoskeleton assembly control proteinYNL243w SLA2 cytoskeleton assembly control proteinYLL001w DNM1 dynamin-related proteinYKR054c DYN1 dynein heavy chain, cytosolicYDR424c DYN2 dynein light chain 1, cytosolicYKL007w CAP1 F-actin capping protein, α subunitYIL034c CAP2 F-actin capping protein, β subunitYLR212c TUB4 γ tubulin

YMR138w CIN4 GTP-binding proteinYOR156c NFI1 interacts with Cdc12p in 2-hybrid assayYML104c MDM1 intermediate filament proteinYLL021w SPA2 involved in cell polarityYPL241c CIN2 involved in chromosome segregationYDR085c AFR1 involved in morphogenesis of the mating

projectionYEL061c CIN8 kinesin-related proteinYPR141c KAR3 kinesin-related proteinYBL063w KIP1 kinesin-related proteinYPL155c KIP2 kinesin-related proteinYKL079w SMY1 kinesin-related proteinYBR172c SMY2 kinesin-related proteinYOR058c ASE1 microtubule-associated proteinYJL042w MHP1 microtubule-associated proteinYMR294w JNM1 mitosis protein, involved in nuclear

migrationYBL034c STU1 mitotic spindle proteinYOR326w MYO2 myosin heavy chainYAL029c MYO4 myosin heavy chain, unconventional

(class V) isoformYMR109w MYO5 myosin IYKL129c MYO3 myosin type IYHR023w MYO1 myosin-1 isoform (type II myosin) heavy

chainYCL029c BIK1 nuclear fusion proteinYOR122c PFY1 profilinYDR164c SEC1 protein transport proteinYDR388w RVS167 reduced viability upon starvation proteinYNL084c END3 required for endocytosis and cytoskeletal

organizationYBR130c SHE3 required for mother cell-specific

expression of HOYGR078c PAC10 required in the absence of Cin8pYDR488c PAC11 required in the absence of Cin8pYER007w PAC2 required in the absence of Cin8pYJR076c CDC11 septinYHR107c CDC12 septinYDR218c SPR28 septin-related sporulation proteinYNL059c similarity to actinYLR085c similarity to actin and actin-related

proteinsYLR429w similarity to actin binding protein coroninYPR034w similarity to actinsYGL003c similarity to C. elegans CDC20 protein

and human p55CDCYCR009c RVS161 similarity to human amphiphysin and

Rvs167pYER018c similarity to laminsYOR367w similarity to mammalian smooth muscle

protein SM22YIL149c similarity to Mlp1p and myosin heavy

chainsYGL216w similarity to mouse kinesin-related protein

KIF3YKL179c similarity to Nuf1pYJR134c similarity to paramyosin, myosinYPL105c similarity to Smy2pYDR356w NUF1 spindle pole body componentYNL126w SPC98 spindle pole body componentYOL069w NUF2 spindle pole body proteinYGR059w SPR3 sporulation-specific septinYEL071w strong similarity to Aip2pYOR134w BAG7 structural homologue of Sac7pYAL047c SPI6 Stu2p InteractantYKL022c CDC16 subunit of anaphase-promoting complex



(cyclosome)YDR484w SAC2 suppressor of actin mutationYDR389w SAC7 suppressor of actin mutationYNL079c TPM1 tropomyosin 1YIL138c TPM2 tropomyosin 2YPL045w VPS16 vacuolar sorting proteinYLR337w VRP1 verprolin

organization and biogenesis of endoplasmicreticulum and Golgi

YML075c HMG1 3-hydroxy-3-methylglutaryl-CoA reductase1

YLR450w HMG2 3-hydroxy-3-methylglutaryl-CoA reductase2

YJR131w MNS1 α-1,2-mannosidaseYDR483w KRE2 α-1,2-mannosyltransferaseYER001w MNN1 α-1,3-mannosyltransferaseYGL038c OCH1 α-1,6-mannosyltransferaseYGL027c CWH41 β-1,6-glucan assembly proteinYBR110w ALG1 β-mannosyltransferaseYMR015c ERG5 C-22 sterol desaturaseYGR060w ERG25 C-4 sterol methyl oxidaseYLR056w ERG3 C-5 sterol desaturaseYMR202w ERG2 C-8 sterol isomeraseYGL167c PMR1 Ca2+-transporting P-type ATPaseYBR036c CSG2 calcium dependent regulatory proteinYGL203c KEX1 carboxypeptidase (YSC-α)YPR113w PIS1 CDP diacylglycerol-inositol

3-phosphatidyltransferaseYER026c CHO1 CDP-diacylglycerol serine

O-phosphatidyltransferaseYBR029c CDS1 CDP-diacylglycerol synthaseYKL073w LHS1 chaperone of the ER lumenYGR202c PCT1 cholinephosphate cytidylyltransferaseYOL062c APM4 clathrin-associate protein YAP54YPL259c APM1 clathrin-associated protein


gazetteer

YDL195w SEC31 component of the COPII coat of ER-Golgivesicles

YGL200c EMP24 component of the COPII-coated vesicles,24K

YML012w ERV25 component of the COPII-coated vesicles,25K

YHR007c ERG11 cytochrome P450 lanosterol 14a-demethylase

YNL130c CPT1 diacylglycerol cholinephosphotransferaseYMR013c SEC59 dolichol kinaseYPL227c ALG5 dolichol-P-glucose synthetaseYPR183w DPM1 dolichyl-phosphate

β-D-mannosyltransferaseYJR143c PMT4 dolichyl-phosphate-mannose-protein

O-mannosyl transferaseYDL212w SHR3 endoplasmic reticulum membrane proteinYNL238w KEX2 endoproteinase of late Golgi

compartmentYBL040c ERD2 ER lumen protein-retaining receptorYLR378c SEC61 ER protein-translocation complex subunitYPL094c SEC62 ER protein-translocation complex subunitYOR254c SEC63 ER protein-translocation complex subunitYBR171w SEC66 ER protein-translocation complex subunitYLR292c SEC72 ER protein-translocation complex subunitYDR086c SSS1 ER protein-translocation complex subunitYDR331w GPI8 essential for GPI-anchor attachmentYHR190w ERG9 farnesyl-diphosphate farnesyltransferaseYDR519w FKB2 FK506/rapamycin-binding protein of the

ERYJR031c GEA1 GDP/GTP exchange factor for ARFYEL022w GEA2 GDP/GTP exchange factor for ARFYNR026c SEC12 GDP/GTP exchange factor for Sar1pYPR159w KRE6 glucan synthase subunitYGR143w SKN1 glucan synthase subunitYOR067c ALG8 glucosyltransferaseYFL048c EMP47 Golgi membrane proteinYDL192w ARF1 GTP-binding protein of the ARF familyYPL218w SAR1 GTP-binding protein of the ARF familyYFL038c YPT1 GTP-binding protein of the RAB familyYLR262c YPT6 GTP-binding protein of the RAB familyYPR165w RHO1 GTP-binding protein of the RHO subfamily


of RAS-like proteinsYEL042w GDA1 guanosine diphosphataseYDR189w SLY1 hydrophilic suppressor of ypt1 and

member of the Sec1p familyYCR075c ERS1 intracellular protein transport proteinYDL058w USO1 intracellular protein transport proteinYLR220w CCC1 involved in calcium regulationYBR201w DER1 involved in degradation proteins in the ERYOR069w VPS5 involved in Golgi retention and vacuolar

sortingYOR336w KRE5 killer toxin-resistance proteinYHR072w ERG7 lanosterol synthaseYKR061w KTR2 mannosyltransferaseYDL095w PMT1 mannosyltransferaseYAL023c PMT2 mannosyltransferaseYOR321w PMT3 mannosyltransferaseYBL082c RHK1 mannosyltransferaseYJL139c YUR1 mannosyltransferaseYKR001c VPS1 member of the dynamin family of

GTPasesYJR073c OPI3 methylene-fatty-acyl-phospholipid

synthaseYNL064c YDJ1 mitochondrial and ER import proteinYPL085w SEC16 multidomain vesicle coat proteinYHR042w NCP1 NADPH-cytochrome P450 reductaseYFL025c BST1 negative regulator of COPII vesicle

formationYJL034w KAR2 nuclear fusion proteinYJL002c OST1 oligosaccharyltransferase α subunitYEL002c WBP1 oligosaccharyltransferase β subunit YMR149w SWP1 oligosaccharyltransferase δ subunitYOR103c OST2 oligosaccharyltransferase ε subunitYOR085w OST3 oligosaccharyltransferase γ subunitYGL022w STT3 oligosaccharyltransferase subunitYHR057c CYP2 peptidyl-prolyl cis-trans isomeraseYCR069w SCC3 peptidyl-prolyl cis-trans isomerase YDR304c CYP5 peptidyl-prolyl cis-trans isomerase D

(cyclophilin D) of the ERYGR157w CHO2 phosphatidylethanolamine

N-methyltransferaseYGR170w PSD2 phosphatidylserine decarboxylase 2YDR518w EUG1 protein disulphide isomeraseYCL043c PDI1 protein disulphide-isomerase YHR079c IRE1 protein kinaseYEL036c ANP1 protein of the endoplasmatic reticulumYCR067c SED4 protein of the endoplasmic reticulumYIL004c BET1 protein transport proteinYDR040c ENA1 P-type ATPase involved in Na+ and Li+

effluxYKL212w SAC1 recessive suppressor of secretory defectYLR088w GAA1 required for attachment of GPI anchor

onto proteinsYPL050c MNN9 required for complex N-glycosylationYCL001w RER1 required for correct localization of Sec12pYGL145w TIP20 required for ER to Golgi transportYDR414c ERD1 required for retention of luminal ER

proteinsYMR004w MVP1 required for vacuolar protein sortingYDR498c SEC20 secretory pathway proteinYJR010c-a SPC1 signal peptidase 10.8K subunitYML055w SPC2 signal peptidase 18K subunitYDR292c SRP101 signal recognition particle receptor,

α subunitYIR022w SEC11 signal sequence processing proteinYAL058w CNE1 similarity to calnexin

YDR245w MNN10 similarity to S. pombegalactosyltransferase

YMR214w SCJ1 similarity to to E. coli dnaJYHR123w EPT1 sn-1,2-diacylglycerol ethanolamine- and

cholinephosphotransferaseYKL006c-a SFT1 SNARE-like proteinYGR175c ERG1 squalene monooxygenaseYGL055w OLE1 stearoyl-CoA desaturaseYLR080w strong similarity to Emp47pYER087c-a SEB1 strong similarity to mammalian Sec61β

subunitYOR099w KTR1 strong similarity to mannosyltransferasesYGL226c-a OST5 subunit of N-oligosaccharyltransferase,

ζ subunitYDR297w SUR2 suppressor of rvs161 and rvs167

mutationsYBL102w SFT2 suppressor of sed5 ts mutantsYLR026c SED5 syntaxin (T-SNARE)YOR075w UFE1 syntaxin (T-SNARE) of the ERYOR219c STE13 type IV dipeptidyl aminopeptidaseYMR022w QRI8 ubiquitin-conjugating enzymeYER100w UBC6 ubiquitin-conjugating enzymeYBR243c ALG7 UDP-N-acetylglucosamine-1-phosphate

transferaseYGR105w VMA21 vacuolar ATPase assembly integral

membrane proteinYBL017c PEP1 vacuolar protein sorting/targeting proteinYGL225w GOG5 vanadate-resistance protein

organization and biogenesis of chromosomestructure

YJL081c ACT3 actin-related proteinYDL220c CDC13 cell division control proteinYBR195c MSI1 chromatin assembly complex, subunit

p50YML102w CAC2 chromatin assembly complex, subunit


p90YGR218w CRM1 chromosome region maintenance proteinYNL216w RAP1 DNA-binding protein with repressor and

activator activityYER159c NCB1 functional homologue of human NC2αYMR072w ABF2 high-mobility group proteinYPL127c HHO1 histone H1 proteinYDR225w HTA1 histone H2AYBL003c HTA2 histone H2A.2YDR224c HTB1 histone H2BYBL002w HTB2 histone H2B.2YBR010w HHT1 histone H3YNL031c HHT2 histone H3YBR009c HHF1 histone H4YNL030w HHF2 histone H4YER161c SPT2 HMG-like chromatin proteinYPL254w HFI1 interacts functionally with histone H2AYNR010w CSE2 interacts with centromeric element CDEIIYGR099w TEL2 involved in controlling telomere length

and position effectYJR060w CBF1 kinetochore proteinYGR140w CBF2 kinetochore protein complex CBF3, 110K

subunit YMR094w CTF13 kinetochore protein complex CBF3, 58K

subunitYMR168c CEP3 kinetochore protein complex CBF3, 71K

subunit YDR328c SKP1 kinetochore protein complex CBF3,

subunit DYIL072w HOP1 meiosis-specific proteinYLR263w RED1 meiosis-specific proteinYLR457c NBP1 Nap1p-binding proteinYDR162c NBP2 Nap1p-binding proteinYBR089c-a NHP6B nonhistone chromosomal proteinYPR052c NHP6A nonhistone chromosomal protein related

to mammalian HMG1YDR174w HMO1 nonhistone proteinYDL002c HMO2 nonhistone proteinYKR048c NAP1 nucleosome assembly protein IYCL011c GBP2 potential telomere-associated proteinYGL238w CSE1 probable kinetochore proteinYGL194c RTL1 putative deacetylase YBR275c RIF1 Rap1p-interacting factor 1YKL089w MIF2 required for normal chromosome

segregation and spindle integrityYJL074c SMC3 required for structural maintenance of

chromosomesYLR086w similarity to chromosome condensation

proteinsYML069w POB3 similarity to HMG proteinsYOR053w similarity to protaminesYNL206c similarity to structure-specific recognition

proteinsYDL208w NHP2 strong similarity to high mobility group

(HMG) familyYEL026w strong similarity to high mobility group-like

protein Nhp2pYOL012c HTA3 strong similarity to histone H2A proteinYKL049c CSE4 strong similarity to histone H3YOR213c subunit of the RSC complexYCR052w RSC6 subunit of the RSC complexYFR037c RSC8 subunit of the RSC complexYLR321c SFH1 subunit of the RSC complexYIL126w STH1 subunit of the RSC complexYDR285w ZIP1 synaptonemal complex proteinYLR233c EST1 telomere elongation proteinYBL088c TEL1 telomere length control proteinYPL128c TBF1 telomere TTAGGG repeat-binding factor 1

YGR274c TAF145 TFIID subunit (TBP-associated factor),145K

YGR187c HGH1 weak similarity to human Hmg1p andHmg2p

YGR285c ZUO1 zuotin (Z-DNA binding protein)

mitochondrial organization and biogenesis

YHR037w PUT2 1-pyrroline-5-carboxylate dehydrogenaseYNL104c LEU4 2-isopropylmalalate synthaseYMR282c AEP2 2’-O-ribosyl phosphate transferaseYIL125w KGD1 2-oxoglutarate dehydrogenase complex

E1 componentYDR148c KGD2 2-oxoglutarate dehydrogenase complex

E2 componentYOL096c COQ3 3,4-dihydroxy-5-hexaprenylbenzoate

methyltransferaseYMR287c MSU1 3’-5’ exonuclease for RNA 3’ ss-tail,

mitochondrialYDR232w HEM1 5-aminolevulinate synthaseYML009c MRPL39 60S ribosomal protein, mitochondrialYMR108w ILV2 acetolactate synthaseYCL009c ILV6 acetolactate synthase, regulatory subunitYAL054c ACS1 acetyl-CoA synthetaseYER069w ARG5,6 acetylglutamate kinase and

acetylglutamyl-phosphate reductaseYOL140w ARG8 acetylornithine aminotransferaseYLR304c ACO1 aconitate hydrataseYDR234w LYS4 aconitate hydrataseYER170w ADK2 adenylate kinase, mitochondrialYMR056c AAC1 ADP/ATP carrier protein (MCF)YBL030c AAC2 ADP/ATP carrier protein (MCF)YBR085w AAC3 ADP/ATP carrier protein (MCF)YMR083w ADH3 alcohol dehydrogenase IIIYER073w aldehyde dehydrogenase (NAD+)YMR170c ALD5 aldehyde dehydrogenase 2 (NAD+),

mitochondrialYER086w ILV1 anabolic serine and threonine

dehydratase YJL209w CBP1 apo-cytochrome b pre-mRNA processing

proteinYBR120c CBP6 apo-cytochrome b pre-mRNA processing

proteinYHL038c CBP2 apo-cytochrome b pre-mRNA processing

protein 2YHR091c MSR1 arginyl-tRNA synthetase, mitochondrialYCR024c asn-tRNA synthetase, mitochondrialYKL106w AAT1 aspartate transaminase, mitochondrialYPL104w MSD1 aspartate-tRNA ligase, mitochondrialYGR008c STF2 ATPase stabilizing factorYDL130w-a STF1 ATPase stabilizing factor, 10KYDR377w ATP17 ATPase synthase subunit fYMR301c ATM1 ATP-binding cassette transporter protein,

mitochondrialYBL022c PIM1 ATP-dependent protease, mitochondrialYPL029w SUV3 ATP-dependent RNA helicase,

mitochondrialYER061c CEM1 β-keto-acyl-ACP synthaseYHR208w TWT1 branched chain amino-acid

aminotransferase, mitochondrialYBR084w MIS1 C1-tetrahydrofolate synthase,

mitochondrialYML042w CAT2 carnitine O-acetyltransferaseYER026c CHO1 CDP-diacylglycerol serine

O-phosphatidyltransferaseYNR001c CIT1 citrate (si)-synthase, mitochondrialYPR001w CIT3 citrate (si)-synthase, mitochondrialYBR291c CTP1 citrate transport protein, mitochondrial

(MCF)YOR316c COT1 cobalt accumulation proteinYOR017w PET127 component of mitochondrial translation

systemYPR155c NCA2 control of mitochondrial synthesis of

Atp6p and Atp8pYKL011c CCE1 cruciform-cutting endonuclease,

mitochondrialYML078w CPR3 cyclophilin (peptidylprolyl isomerase),

mitochondrialYDR197w CBS2 cytochrome b translational activator

proteinYIL043c CBR1 cytochrome b5 reductaseYKL150w MCR1 cytochrome b5 reductaseYKL141w SDH3 cytochrome b560 subunit of respiratory

complex IIYJR048w CYC1 cytochrome c isoform 1YEL039c CYC7 cytochrome c isoform 2YOR037w CYC2 cytochrome c mitochondrial import factorYER058w PET117 cytochrome c oxidase assembly factorYPL132w COX11 cytochrome c oxidase assembly proteinYML129c COX14 cytochrome c oxidase assembly proteinYDR079w PET100 cytochrome c oxidase assembly proteinYGL187c COX4 cytochrome c oxidase subunit IVYNL052w COX5A cytochrome c oxidase subunit V.A YIL111w COX5B cytochrome c oxidase subunit VbYHR051w COX6 cytochrome c oxidase subunit VIYGL191w COX13 cytochrome c oxidase subunit VIaYLR038c COX12 cytochrome c oxidase subunit VIBYMR256c COX7 cytochrome c oxidase subunit VIIYDL067c COX9 cytochrome c oxidase subunit VIIAYLR395c COX8 cytochrome c oxidase subunit VIIIYKR066c CCP1 cytochrome c peroxidase YOR065w CYT1 cytochrome c1YER141w COX15 cytochrome oxidase assembly factorYER154w OXA1 cytochrome oxidase biogenesis proteinYOR386w PHR1 deoxyribodipyrimidine photo-lyaseYLR348c dicarboxylate carrier proteinYFL018c LPD1 dihydrolipoamide dehydrogenase YNL071w LAT1 dihydrolipoamide S-acetyltransferase


gazetteer

YJR016c ILV3 dihydroxy-acid dehydrataseYDL174c DLD1 D-lactate ferricytochrome c

oxidoreductase (D-LCR)YML061c PIF1 DNA helicase involved in mitochondrial

DNA repair and telomere lengthYHR120w MSH1 DNA mismatch repair protein,

mitochondrialYOR330c MIP1 DNA-directed DNA polymerase γ, catalytic

subunit, mitochondrialYFL036w RPO41 DNA-directed RNA polymerase,

mitochondrialYBR252w DUT1 dUTP pyrophosphatase, mitochondrialYOR211c MGM1 dynamin-like proteinYGR207c ETF-β electron-transferring flavoprotein,

β subunitYLR393w ATP10 F1F0 ATPase complex assembly proteinYNL315c ATP11 F1F0-ATPase complex assembly proteinYJL180c ATP12 F1F0-ATPase complex assembly proteinYKL016c ATP7 F1F0-ATPase complex, F0 D subunitYBL099w ATP1 F1F0-ATPase complex, F1 α subunitYJR121w ATP2 F1F0-ATPase complex, F1 β subunitYDL004w ATP16 F1F0-ATPase complex, F1 δ subunitYPL078c ATP4 F1F0-ATPase complex, F1 δ subunitYPL271w ATP15 F1F0-ATPase complex, F1 ε subunitYBR039w ATP3 F1F0-ATPase complex, F1 γ subunitYDR298c ATP5 F1F0-ATPase complex, OSCP subunitYLR295c ATP14 F1F0-ATPase complex, subunit hYIL134w FLX1 FAD carrier protein, mitochondrial (MCF)YPL172c COX10 farnesyl transferaseYOR176w HEM15 ferrochelatase YPL262w FUM1 fumarate hydrataseYOL033w MSE1 glutamyl-tRNA synthetase, mitochondrialYOL059w GPD3 glycerol-3-phosphate dehydrogenase

(NAD+), mitochondrialYIL155c GUT2 glycerol-3-phosphate dehydrogenase,

mitochondrialYMR189w GSD2 glycine decarboxylase subunitYDR019c GCV1 glycine decarboxylase T subunitYFL016c MDJ1 heat-shock protein - chaperoneYOR232w MGE1 heat-shock protein - chaperoneYLR259c HSP60 heat-shock protein - chaperone,


mitochondrialYDR258c HSP78 heat-shock protein of clpb family of ATP-

dependent proteases, mitochondrialYBR003w COQ1 hexaprenyl pyrophosphate synthetase YMR072w ABF2 high mobility group proteinYAL039c CYC3 holocytochrome c synthase (cytochrome

c haem lyase)YKL087c CYT2 holocytochrome c1 synthaseYMR038c LYS7 homocitrate dehydrogenaseYDL181w INH1 inhibitor of mitochondrial ATPaseYMR267w PPA2 inorganic pyrophosphatase, mitochondrialYLL009c COX17 interacts genetically with SCO1 and SCO2

in cytochrome oxidase assemblyYGR028w MSP1 intra-mitochondrial sorting proteinYJR034w PET191 involved in assembly of cytochrome

oxidaseYMR302c PRP12 involved in early maturation of pre-rRNAYOL009c MDM12 involved in mitochondrial inheritanceYAL010c MDM10 involved in mitochondrial morphology and

inheritanceYIR021w MRS1 involved in mitochondrial RNA splicing of

COB mRNAYBR037c SCO1 involved in stabilization of Cox1p and

Cox2pYNL066w SUN4 involved in the aging processYCL017c NFS1 involved in tRNA processing and

mitochondrial metabolsimYNL037c IDH1 isocitrate dehydrogenase (NAD+) subunit


2, mitochondrialYDL066w IDP1 isocitrate dehydrogenase (NADP+),

mitochondrialYPL040c ISM1 isoleucine-tRNA ligase, mitochondrialYLR355c ILV5 ketol-acid reducto-isomeraseYML054c CYB2 lactate dehydrogenase cytochrome b2YLR382c NAM2 leucine-tRNA ligase, mitochondrialYOR196c LIP5 lipoic acid synthaseYNL073w MSK1 lysyl-tRNA synthetase, mitochondrialYKL085w MDH1 malate dehydrogenase, mitochondrialYOR130c ARG11 member of the mitochondrial carrier

family (MCF)YDL198c YHM1 member of the mitochondrial carrier

family (MCF)YGR171c MSM1 methionyl-tRNA synthetaseYGR029w ERV1 mitochondrial biogenesis and regulation

of cell cycleYBR192w RIM2 mitochondrial carrier protein (MCF)YPR058w YMC1 mitochondrial carrier protein (MCF)YBR104w YMC2 mitochondrial carrier protein (MCF)YOR020c HSP10 mitochondrial chaperoninYJR144w MGM101 mitochondrial genome maintenance

proteinYMR023c MSS1 mitochondrial GTPase involved in

expression of COX1YNR017w MAS6 mitochondrial inner membrane import



translocase subunitYMR035w IMP2 mitochondrial inner membrane protease

subunitYKL134c (MIP1) mitochondrial intermediate peptidase

YNL131w TOM22 mitochondrial outer membrane importreceptor subunit

YGR082w TOM20 mitochondrial outer membrane importreceptor subunit, 20K

YMR060c TOM37 mitochondrial outer membrane importreceptor subunit, 37K

YMR203w TOM40 mitochondrial outer membrane importreceptor subunit, 40K

YOR045w TOM6 mitochondrial outer membrane importreceptor subunit, 6K

YNL070w TOM7 mitochondrial outer membrane importreceptor subunit, 7K

YNL055c POR1 mitochondrial outer membrane porinYNL121c TOM70 mitochondrial outer membrane

specialized import receptorYGL143c MRF1 mitochondrial peptide chain release factorYLR163c MAS1 mitochondrial processing peptidaseYHR024c MAS2 mitochondrial processing peptidase,

catalytic 53K (α) subunitYMR150c IMP1 mitochondrial proteaseYDR375c BCS1 mitochondrial protein of the

CDC48/PAS1/SEC18 (AAA) family ofATPases

YDR120c TRM1 N2,N2-dimethylguanine tRNAmethyltransferase

YML120c NDI1 NADH-ubiquinone-6 oxidoreductaseYOR355w GDS1 nam9-1 suppressorYJL208c NUC1 nuclease, mitochondrialYAR035w YAT1 outer carnitine acetyltransferase,

mitochondrialYNR041c COQ2 para-hydroxybenzoate-

polyprenyltransferaseYPR047w MSF1 phenylalanine-tRNA ligase α subunit,

mitochondrialYJR077c MIR1 phosphate transport protein,

mitochondrial (MCF)YNL169c PSD1 phosphatidylserine decarboxylase 1YLR203c MSS51 possibly involved in translational

activation of COX1 and COB mRNAYGL068w probable ribosomal protein L12YLR168c (MSF1) probably involved in intramitochondrial

protein sortingYLR142w PUT1 proline oxidaseYER017c AFG3 protease of the SEC18/CDC48/PAS1



family of ATPases (AAA)YDL044c MTF2 protein involved in mRNA splicing and

protein synthesis, mitochondrialYIL136w OM45 protein of the outer mitochondrial

membraneYAL011w FUN36 protein of unknown functionYJL023c PET130 protein synthesis protein, mitochondrialYER014w HEM14 protoporphyrinogen oxidase,

mitochondrialYER178w PDA1 pyruvate dehydrogenase (lipoamide)



XYJR095w ACR1 regulator of acetyl-CoA synthetase activityYBR091c MRS5 regulator of mitochondrial intron splicingYPL215w CBP3 required for assembly of cytochrome bc1

complexYEL059c-a SOM1 required for mitochondrial Imp1 peptidase

functionYLL006w MMM1 required for mitochondrial shape and

structureYKL093w MBR1 required for optimal growth on glycerolYLR067c PET309 required for stability and translation of

COX1 mRNAYMR257c PET111 required for translation of COX2 mRNAYBL080c PET112 required to maintain RHO+ mitochondrial

DNAYBR185c MBA1 respiratory chain assembly proteinYML091c RPM2 ribonuclease P, mitochondrialYKL170w MRPL38 ribosomal protein L14, mitochondrialYJL063c MRPL8 ribosomal protein L17, mitochondrialYPR166c MRP2 ribosomal protein S14YPL013c ribosomal protein S16, mitochondrialYBR251w MRPS5 ribosomal protein S5, mitochondrialYBR146w MRPS9 ribosomal protein S9, mitochondrialYKR006c MRPL13 ribosomal protein YmL13, mitochondrialYNL005c MRPL2 ribosomal protein YmL2, mitochondrialYKR085c MRPL20 ribosomal protein YmL20, mitochondrialYBR282w MRPL27 ribosomal protein YmL27, mitochondrialYDR462w ribosomal protein YmL28, mitochondrialYNL252c ribosomal protein YmL30, mitochondrialYKL138c MRPL31 ribosomal protein YmL31, mitochondrialYCR003w MRPL32 ribosomal protein YmL32, mitochondrialYBR122c MRPL36 ribosomal protein YmL36, mitochondrialYBR268w MRPL37 ribosomal protein YmL37, mitochondrialYPL173w ribosomal protein YmL40, mitochondrialYGR076c MRPL25 ribosomal protein YmR26 (YML25),

mitochondrialYMR225c MRPL44 ribosomal protein YmR44, mitochondrialYML025c ribosomal protein, mitochondrialYDR347w MRP1 ribosomal protein, mitochondrialYGR084c MRP13 ribosomal protein, mitochondrialYKL003c MRP17 ribosomal protein, mitochondrialYDR405w MRP20 ribosomal protein, mitochondrialYHL004w MRP4 ribosomal protein, mitochondrialYKL167c MRP49 ribosomal protein, mitochondrialYKL142w MRP8 ribosomal protein, mitochondrialYLR312w-a MRPL15 ribosomal protein, mitochondrial

YBL038w MRPL16 ribosomal protein, mitochondrialYMR193w MRPL24 ribosomal protein, mitochondrialYMR024w MRPL3 ribosomal protein, mitochondrialYMR286w MRPL33 ribosomal protein, mitochondrialYLR439w MRPL4 ribosomal protein, mitochondrialYHR147c MRPL6 ribosomal protein, mitochondrialYGR220c MRPL9 ribosomal protein, mitochondrialYDR337w MRPS28 ribosomal protein, mitochondrialYNL137c NAM9 ribosomal protein, mitochondrialYOR158w PET123 ribosomal protein, mitochondrialYCR046c PETCR46 ribosomal protein, mitochondrialYFR049w YMR31 ribosomal protein, mitochondrialYDR194c MSS116 RNA helicase of the DEAD box family,

mitochondrialYMR228w MTF1 RNA polymerase specific factor,

mitochondrialYOR334w MRS2 RNA splicing protein and member of the

mitochondrial carrier family (MCF)YJL133w MRS3 RNA splicing protein and member of the

mitochondrial carrier family (MCF)YKR052c MRS4 RNA splicing protein and member of the

mitochondrial carrier family (MCF)YOR201c PET56 rRNA (guanosine-2’-O-)-methyltransferaseYBR263w SHM1 serine hydroxymethyltransferase,

mitochondrialYPR037c similarity to Erv1p and rat ALR proteinYDR376w ARH1 similarity to human adrenodoxin

reductaseYBL013w similarity to methionyl-tRNA

formyltransferaseYJR113c similarity to mitochondrial ribosomal

protein S7YKL120w PMT similarity to mitochondrial uncoupling

protein (MCF)YMR244w similarity to NCA3 and SUN4 proteinYOR150w similarity to ribosomal protein L13YPR134w MSS18 splicing proteinYGR222w PET54 splicing protein and translational activator,

mitochondrialYCR028c-a RIM1 ssDNA-binding protein, mitochondrialYKL192c strong similarity to acyl-carrier proteinsYBR024w SCO2 strong similarity to Sco1pYHR117w TOM71 strong similarity to Tom70p/Mas70pYKL148c SDH1 succinate dehydrogenase flavoprotein YLL041c SDH2 succinate dehydrogenase iron-sulphur

protein subunitYDR178w SDH4 succinate dehydrogenase membrane

anchor subunit for Sdh2pYHR008c SOD2 superoxide dismutase (Mn), mitochondrialYHR050w SMF2 suppressor of mitochondrial matrix

mutantYKL194c MST1 threonine-tRNA ligase, mitochondrialYLR069c MEF1 translation elongation factor G,

mitochondrialYOR187w TUF1 translation elongation factor TU,

mitochondrialYJL102w MEF2 translation elongation factor,

mitochondrialYOL023w IFM1 translation initiation factor 2, mitochondrialYDL069c CBS1 translational activator of cob mRNAYER153c PET122 translational activator of cytochrome c

oxidase subunit IIIYNR045w PET494 translational activator, mitochondrialYOR274w MOD5 tRNA isopentenyltransferaseYER168c CCA1 tRNA nucleotidyltransferaseYDR268w MSW1 tryptophanyl-tRNA synthetase,

mitochondrialYPL097w MSY1 tyrosyl-tRNA synthetaseYFR033c QCR6 ubiquinol-cytochrome c reductase 17K

proteinYPR191w QCR2 ubiquinol-cytochrome c reductase 40K

subunit IIYBL045c COR1 ubiquinol-cytochrome c reductase 44K

core proteinYHR001w-a QCR10 ubiquinol-cytochrome c reductase 8.5K

subunitYGR174c CBP4 ubiquinol-cytochrome c reductase

assembly factorYGL119w ABC1 ubiquinol-cytochrome c reductase

complex assembly proteinYEL024w RIP1 ubiquinol-cytochrome c reductase iron-

sulphur protein YDR529c QCR7 ubiquinol-cytochrome c reductase subunit

7YGR183c QCR9 ubiquinol-cytochrome c reductase subunit

9YJL166w QCR8 ubiquinol-cytochrome c reductase subunit

VIIIYML021c UNG1 uracil-DNA glycosylaseYGR094w VAS1 valyl-tRNA synthetaseYIL114c POR2 voltage-dependent anion channel

(YVDAC2)YNL237w YTP1 weak similarity to mitochondrial electron

transport proteins

peroxisomal organization and biogenesis

YIL160c POT1 acetyl-CoA C-acyltransferase, peroxisomalYAL054c ACS1 acetyl-CoA synthetaseYGL205w POX1 acyl-CoA oxidaseYBR222c PCS60 AMP-binding protein, peroxisomalYML042w CAT2 carnitine O-acetyltransferaseYDR256c CTA1 catalase A, peroxisomalYCR005c CIT2 citrate (si)-synthase, peroxisomalYKR009c FOX2 hydratase-dehydrogenase-epimerase,

peroxisomalYER065c ICL1 isocitrate lyaseYKL188c PAT1 long-chain-fatty-acid transporter


gazetteer

YPL147w PXA1 long-chain-fatty-acid transporterYER015w FAA2 long-chain-fatty-acid-CoA ligaseYDL078c MDH3 malate dehydrogenase, peroxisomalYNL117w MLS1 malate synthase 1YIR031c DAL7 malate synthase 2YDR329c PAS3 peroxisomal assembly proteinYDR265w PAS4 peroxisomal assembly proteinYJL210w PAS5 peroxisomal assembly proteinYNL329c PAS8 peroxisomal assembly proteinYDR142c PAS7 peroxisomal import proteinYOL147c PMP27 peroxisomal membrane proteinYLR191w PAS20 peroxisomal protein involved in protein

importYDR244w PAS10 putative peroxisomal targeting signal

receptorYLR109w similarity to C. boidinii peroxisomal

membrane protein 20K AYGR077c similarity to peroxisomal matrix protein

Per1pYLR251w similarity to peroxisomal rat membrane

protein PMP22YNL202w SPS19 sporulation-specific proteinYGR133w PAS2 ubiquitin-conjugating enzymeYBR204c weak similarity to peroxisomal serine-

active lipase

endosomal organization and biogenesis

YKL135c APL2 β-adaptinYNL192w CHS1 chitin synthase IYBR023c CHS3 chitin synthase IIIYJR058c APS2 clathrin-associated protein 17, small

subunitYJR005w APL1 clathrin-associated protein complex,

β subunitYBR288c APM3 clathrin-associated protein complex,

medium subunitYLR170c APS1 clathrin-associated protein complex, small

subunit AP19YDL145c RET1 coatomer complex α subunitYDR238c SEC26 coatomer complex β subunit of secretory

pathway vesiclesYGL137w SEC27 coatomer complex β́ subunitYFR051c RET2 coatomer complex δ subunitYNL287w SEC21 coatomer complex γ subunitYPL010w RET3 coatomer complex ζ subunitYPR181c SEC23 component of COPII coat of ER-golgi

vesiclesYDR170c SEC7 component of non-clathrin vesicle coatYLR083c EMP70 endosomal proteinYPR017c DSS4 GDP/GTP exchange factor for Sec4pYOR089c VPS21 GTP-binding proteinYDL137w ARF2 GTP-binding protein of the ARF familyYML001w YPT7 GTP-binding protein of the RAB familyYFL005w SEC4 GTP-binding protein of the RAS

superfamilyYLR268w SEC22 high copy suppressor of ypt1 null

mutationYPL085w SEC16 multidomain vesicle proteinYLR208w SEC13 protein transport proteinYKL196c similarity to Sec22pYLR080w strong similarity to Emp47pYDR107c strong similarity to Emp70pYAL030w SNC1 strong similarity to synaptic vesicle-

associated membrane proteinYOR327c SNC2 strong similarity to synaptobrevinYBL050w SEC17 transport vesicle fusion proteinYNR006w VPS27 vacuolar protein sorting-associated

proteinYBR080c SEC18 vesicular-fusion protein, functional

homologue of NSFYLR078c BOS1 weak similarity to synaptobrevin

(V-SNARE)

vacuolar and lysosomal organization andbiogenesis

YGL156w AMS1 α-mannosidaseYBR286w APE3 aminopeptidase Y, vacuolarYKL103c LAP4 aminopeptidase yscI, vacuolarYPL154c PEP4 aspartyl proteaseYDL128w VCX1 Ca2+-transport (H+/Ca2+ exchange) protein,

vacuolarYGL006w PMC1 Ca2+-transporting P-type ATPaseYMR297w PRC1 carboxypeptidase y, serine-type proteaseYHR028c DAP2 dipeptidyl aminopeptidase BYDR135c YCF1 glutathione S-conjugate transporter,

vacuolarYJL172w CPS1 Gly-X carboxypeptidase YSCS YKL119c VPH2 H+-ATPase assembly protein, vacuolarYHR039c-a VMA10 H+-ATPase V0 domain 13K subunit,









vacuolar

YPR036w VMA13 H+-ATPase V1 domain 54K subunit,vacuolar

YBR127c VMA2 H+-ATPase V1 domain 60K subunit,vacuolar

YDL185w TFP1 H+-ATPase V1 domain 69K subunit,vacuolar

YFR019w FAB1 probable PI P 5-kinaseYEL060c PRB1 protease B, vacuolarYDR481c PHO8 repressible vacuolar alkaline phosphataseYIL099w SGA1 sporulation specific glucan

1,4-—glucosidaseYOR036w PEP12 syntaxin (T-SNARE)YOR106w VAM3 syntaxin related proteinYMR231w PEP5 vacuolar biogenesis proteinYLR148w PEP3 vacuolar membrane proteinYGL212w VAM7 vacuolar morphogenesis proteinYJL053w PEP8 vacuolar protein-sorting/targeting proteinYJL154c VPS35 vacuolar protein-sorting proteinYDR323c PEP7 vacuolar segregation proteinYPL045w VPS16 vacuolar sorting proteinYDR495c VPS3 vacuolar sorting proteinYLR396c VPS33 vacuolar sorting proteinYPR173c VPS4 vacuolar sorting protein

other cellular organization and biogenesisactivities

YKL157w APE2 aminopeptidase yscIIYIL015w BAR1 barrier pepsin YJL174w KRE9 cell wall synthesis proteinYBR092c PHO3 constitutive acid phosphatase YLR286c CTS1 endochitinaseYLR300w EXG1 exo-1,3-—glucanase (I/II), major isoformYIR019c STA1 extracellular α-1,4-glucan glucosidaseYPL187w MFα1 mating pheromone α-1 factorYGL089c MFα2 mating pheromone α-2 factorYDR461w MFA1 mating pheromone a-factor 1YNL145w MFA2 mating pheromone a-factor 2YKL163w PIR3 member of the Pir1p/Pir2p/Pir3p familyYBR093c PHO5 repressible acid phosphatase YKL164c PIR1 required for tolerance to heat-shockYML008c ERG6 S-adenosyl-methionine δ-24-sterol-c-

methyltransferaseYAR071w PHO11 secreted acid phosphataseYHR215w PHO12 secreted acid phosphataseYNL160w YGP1 secreted glycoproteinYLR250w SSP120 secretory proteinYBR046c ZTA1 similarity to ζ-crystallinYMR215w similarity to GAS1 proteinYNL275w similarity to human band 3 anion

transport proteinYIL162w SUC2 sucrose hydrolyzing enzyme

Signal transductionpheromone response generation

YDR264c AKR1 ankyrin repeat-containing proteinYPL161c BEM4 bud emergence proteinYCL027w FUS1 cell fusion proteinYNL053w MSG5 dual-specifity protein phosphataseYJL157c FAR1 factor arrest proteinYAL041w CDC24 GDP/GTP exchange factor for Cdc42pYHR005c GPA1 GTP-binding protein α subunit of the



pheromone pathwayYLR229c CDC42 GTP-binding protein of RAS superfamilyYNL173c MDG1 GTP-binding protein of the pheromone

pathwayYER020w GPA2 guanine nucleotide-binding regulatory

proteinYLR452c SST2 involved in desensitization to α-factor

pheromoneYMR052w FAR3 involved in pheromone-mediated cell

cycle arrestYDR461w MFA1 mating pheromone a-factor 1YIL047c SYG1 member of the major facilitator

superfamilyYBL016w FUS3 mitogen-activated protein kinase (MAP

kinase)YFL026w STE2 pheromone α-factor receptorYKL178c STE3 pheromone α-factor receptorYCL032w STE50 pheromone response pathway proteinYDR103w STE5 pheromone signal transduction pathway

proteinYGR040w KSS1 ser/thr protein kinase of the MAP kinase

familyYLR362w STE11 ser/thr protein kinase of the MEKK familyYHL007c STE20 ser/thr protein kinase of the pheromone

pathwayYDL159w STE7 ser/thr/tyr protein kinase of MAP kinase

kinase familyYHR146w similarity to pheromone-response

G-protein YNL173cYHR084w STE12 transcriptional activator

morphogenesis

YBR200w BEM1 bud emergence mediatorYPL161c BEM4 bud emergence proteinYBR109c CMD1 calmodulinYAL041w CDC24 GDP/GTP exchange factor for Cdc42pYGR070w ROM1 GDP/GTP exchange protein for Rho1p

YLR371w ROM2 GDP/GTP exchange protein for Rho1pYPL115c BEM3 GTPase-activating protein for Cdc42p and

Rho1pYLR229c CDC42 GTP-binding protein of RAS superfamilyYPR165w RHO1 GTP-binding protein of the RHO subfamily


of RAS-like proteinsYPL106c SSE1 heat-shock protein of HSP70 familyYOR149c SMP3 protein kinase C pathway proteinYPL140c MKK2 protein kinase of the MAP kinase kinase

(MEK) familyYDL135c RDI1 RHO GDP dissociation inhibitor with

activity towards Rho1pYOR231w MKK1 ser/thr protein kinaseYBL105c PKC1 ser/thr protein kinaseYHR030c SLT2 ser/thr protein kinase of MAP kinase


kinase C pathwayYOL113w SKM1 Ste20p/PAK-like protein kinaseYGL106w strong similarity to calmodulinsYKL161c strong similarity to ser/thr-specific protein

kinase Slt2pYPL089c RLM1 transcription factor of the MADS box

familyYGL095c VPS45 vacuolar protein sorting-associated

protein

osmosensing

YDL022w GPD1 glycerol-3-phosphate dehydrogenase(NAD+), cytoplasmic

YFL014w HSP12 heat-shock proteinYER118c SSU81 involved in the HOG1 high-osmolarity

signal transduction pathwayYCR073c SSK22 MAP kinase kinase kinaseYNR031c SSK2 MAP kinase kinase kinase of the high-

osmolarity signal transduction pathwayYDL006w PTC1 protein ser/thr phosphatase 2cYLR113w HOG1 ser/thr protein kinase of MAP kinase

(MAPK) familyYHR030c SLT2 ser/thr protein kinase of MAP kinase

familyYKL161c strong similarity to ser/thr-specific protein

kinase Slt2pYIL147c SLN1 two-component signal transducerYLR006c SSK1 two-component signal transducerYJL128c PBS2 tyrosine protein kinase of the MAP kinase

kinase familyYDR069c DOA4 ubiquitin-specific protease

nutritional response

YJL005w CYR1 adenylate cyclaseYLR178c TFS1 cdc25-dependent nutrient- and ammonia-

response cell-cycle regulatorYBR195c MSI1 chromatin assembly complex, subunit

p50YLL016w SDC25 GDP/GTP exchange factorYLR310c CDC25 GDP/GTP exchange factor for Ras1p and

Ras2pYOR101w RAS1 GTP-binding proteinYNL098c RAS2 GTP-binding proteinYER020w GPA2 guanine nucleotide-binding regulatory

proteinYPL106c SSE1 heat-shock protein of HSP70 familyYBR140c IRA1 inhibitory regulator protein of the RAS-

cyclic AMP pathwayYIL119c RPI1 negative regulator of RAS-cAMP pathwayYIR026c YVH1 protein tyrosine phosphataseYOR208w PTP2 protein-tyrosine-phosphataseYOL110w SHR5 RAS suppressorYPL084w BRO1 required for normal response to nutrient

limitationYLR362w STE11 ser/thr protein kinase of the MEKK familyYDL159w STE7 ser/thr/tyr protein kinase of MAP kinase

kinase familyYHR084w STE12 transcriptional activator

other signal-transduction activities

YPL268w PLC1 1-phosphatidylinositol-4,5-bisphosphatephosphodiesterase

YNL138w SRV2 adenylate cyclase-associated protein, 70KYFR014c CMK1 Ca2+/calmodulin-dependent ser/thr

protein kinase, type IYOL016c CMK2 Ca2+/calmodulin-dependent ser/thr

protein kinase, type IIYPL203w TPK2 cAMP-dependent protein kinase 2,

catalytic subunitYKL166c TPK3 cAMP-dependent protein kinase 3,

catalytic subunitYJL164c SRA3 cAMP-dependent protein kinase, catalytic

subunit 1YMR028w TAP42 component of the Tor signalling pathwayYML064c TEM1 GTP-binding protein of the RAS

superfamilyYJL146w IDS2 IME2-dependent signalling proteinYJR066w TOR1 phosphatidylinositol 3-kinaseYKL203c TOR2 phosphatidylinositol 3-kinaseYLR240w VPS34 phosphatidylinositol 3-kinaseYNL267w PIK1 phosphatidylinositol 4-kinaseYNL106c PIE3 phosphatidylinositol phosphate

phosphataseYLR305c STT4 phosphatidylinositol-4-kinaseYDL101c DUN1 protein kinase


gazetteer

YHR079c IRE1 protein kinaseYMR016c SOK2 regulatory protein in the PKA signal

transduction pathwayYGR216c GPI1 required for N-acetylglucosaminyl

phosphatidylinositol synthesisYPL153c SPK1 ser/thr/tyr protein kinaseYHR046c similarity to bovine myo-inositol-1(or 4)-

monophosphataseYBR260c similarity to C. elegans GTPase-activating

proteinYGR136w similarity to chicken growth factor

receptor-binding protein GRB2 homologueYDR379w similarity to Dbm1pYDR208w MSS4 similarity to human PI P 5-kinaseYCR027c similarity to human Ras-related GTP-

binding proteinYDR287w similarity to inositol monophosphataseYLR150w MPT4 specific affinity for guanine-rich

quadruplex nucleic acidsYPR054w SMK1 sporulation-specific MAP kinaseYNL132w strong similarity to A. ambisexualis

antheridiol steroid receptorYHR206w SKN7 transcription factor with similarity to Hsf1p

Cell rescuestress response generation

YFR052w NIN1 26S proteasome regulatory subunitYIL075c SEN3 26S proteasome regulatory subunitYDR074w TPS2 α,α-trehalose-phosphate synthase, 105K


subunitYPR026w ATH1 acid trehalase, vacuolarYIL033c SRA1 cAMP dependent protein kinase,

regulatory subunitYDR477w SNF1 carbon catabolite derepressing ser/thr

protein kinaseYHR135c YCK1 casein kinase I isoformYNL154c YCK2 casein kinase I isoformYGR088w CTT1 catalase T, cytosolicYDR251w PAM1 coiled-coil protein multicopy suppressor

of loss of PP2AYOR010c TIR2 cold shock induced proteinYER011w TIR1 cold-shock induced protein of the Tir1p,

Tip1p familyYDR155c CPH1 cyclophilin (peptidylprolyl isomerase)YEL039c CYC7 cytochrome c isoform 2YER062c HOR2 DL-glycerol phosphataseYDR263c DIN7 DNA damage inducible proteinYGL021w ALK1 DNA damage-responsive proteinYAL015c NTG1 DNA repair proteinYDR519w FKB2 FK506/rapamycin-binding protein of the

ERYGR234w YHB1 flavohemoglobinYIR037w HYR1 glutathione peroxidaseYLL043w FPS1 glycerol channel proteinYNL098c RAS2 GTP-binding proteinYHR064c heat-shock proteinYMR173w DDR48 heat-shock proteinYOL052c-a DDRA2 heat-shock proteinYMR186w HSC82 heat-shock proteinYLL026w HSP104 heat-shock proteinYFL014w HSP12 heat-shock proteinYBR072w HSP26 heat-shock proteinYCR021c HSP30 heat-shock proteinYPL240c HSP82 heat-shock proteinYFL016c MDJ1 heat-shock protein - chaperoneYLR259c HSP60 heat-shock protein - chaperone,


mitochondrialYDR258c HSP78 heat-shock protein of clpb family of ATP-

dependent proteases, mitochondrialYEL030w heat-shock protein of HSP70 familyYAL005c SSA1 heat-shock protein of HSP70 familyYER103w SSA4 heat-shock protein of HSP70 familyYPL106c SSE1 heat-shock protein of HSP70 familyYLL024c SSA2 heat-shock protein of HSP70 family,

cytosolicYBL075c SSA3 heat-shock protein of HSP70 family,

cytosolicYBR169c SSE2 heat-shock protein of the HSP70 familyYGL073w HSF1 heat-shock transcription factorYMR251w-aHOR7 hyperosmolarity-responsive proteinYMR273c ZDS1 involved in negative regulation of cell

polarityYER118c SSU81 involved in the HOG1 high-osmolarity

signal transduction pathwayYDR293c SSD1 involved in the tolerance to high


YKL143w LTV1 low-temperature viability proteinYGR100w MIC1 Mac1p interacting proteinYCR073c SSK22 MAP kinase kinase kinaseYNR031c SSK2 MAP kinase kinase kinase of the high-

osmolarity signal transduction pathwayYJL158c member of the Pir1p/Hsp150p/Pir3p

familyYJL159w member of the Pir1p/Hsp150p/Pir3p

familyYJL160c member of the Pir1p/Hsp150p/Pir3p

familyYKL163w PIR3 member of the Pir1p/Pir2p/Pir3p familyYMR021c MAC1 metal binding activatorYNL064c YDJ1 mitochondrial and ER import protein

YGL178w MPT5 multicopy suppressor of pop2YGR159c NSR1 nuclear localization sequence binding

proteinYGL115w SNF4 nuclear regulatory proteinYJR051w OSM1 osmotic growth proteinYMR175w SIP18 osmotic stress proteinYBR070c SAT2 osmotolerance proteinYHR057c CYP2 peptidyl-prolyl cis-trans isomeraseYOR014w RTS1 potential regulatory subunit of protein

phosphatase 2AYMR174c PAI3 protease A (ysca) inhibitor IA3YHR079c IRE1 protein kinaseYPL140c MKK2 protein kinase of the MAP kinase kinase

(MEK) familyYOL064c MET22 protein ser/thr phosphataseYDL006w PTC1 protein ser/thr phosphatase 2cYDR436w PPZ2 protein ser/thr phosphatase of the PP-1

familyYOR208w PTP2 protein-tyrosine-phosphataseYJR090c GRR1 required for glucose repression and for

glucose and cation transportYPL084w BRO1 required for normal response to nutrient

limitationYKL164c PIR1 required for tolerance to heat-shockYPR005c HAL1 salt-induced proteinYNL160w YGP1 secreted glycoproteinYGL190c CDC55 ser/thr phosphatase 2A regulatory

subunit BYML016c PPZ1 ser/thr phosphatase required for normal

osmoregulationYJL165c HAL5 ser/thr protein kinaseYOR231w MKK1 ser/thr protein kinaseYBL105c PKC1 ser/thr protein kinaseYLR113w HOG1 ser/thr protein kinase of MAP kinase

(MAPK) familyYHR030c SLT2 ser/thr protein kinase of MAP kinase

familyYDL025c ser/thr protein kinase of the DEAD/DEAH

box familyYJL095w BCK1 ser/thr protein kinase of the MEKK familyYER167w BCK2 ser/thr protein kinase of the protein

kinase C pathwayYDR227w SIR4 silencing regulatory proteinYKL088w similarity to C. tropicalis hal3 protein, to C-

term. of Sis2p and to hypothetical proteinYOR054c

YBR044c similarity to chaperonin HSP60 proteinsYJR147w similarity to heat-shock transcription

factorsYGR249w MGA1 similarity to heat-shock transcription

factorsYBR054w YRO2 similarity to HSP30 heat-shock protein

Yro1pYAR020c similarity to members of the Srp1p/Tip1p

familyYCR008w SAT4 similarity to Npr1p and Hal5p protein

kinasesYOR009w similarity to SRP1 and TIR2 proteinsYCR060w similarity to stress inducible protein Sti1pYMR037c stress responsive regulatory proteinYOR027w STI1 stress-induced proteinYBL009w strong similarity to DNA damage

responsive Alk1pYLR369w strong similarity to heat-shock protein 70-

related proteinsYHL046c strong similarity to members of the

Srp1p/Tip1p familyYIL011w strong similarity to members of the

Srp1p/Tip1p familyYOL161c strong similarity to members of the

Srp1p/Tip1p familyYJL223c PAU1 strong similarity to members of the

Srp1p/Tip1p familyYEL049w PAU2 strong similarity to members of the

Srp1p/Tip1p familyYCR104w PAU3 strong similarity to members of the

Srp1p/Tip1p familyYFL020c PAU5 strong similarity to members of the

Srp1p/Tip1p familyYLR461w PAU4 strong similarity to members of the

Tir1p/Tip1p familyYNR076w PAU6 strong similarity to members of the

Tir1p/Tip1p familyYDR033w strong similarity to putative heat-shock

protein Yro2pYKL161c strong similarity to ser/thr-specific protein

kinase Slt2pYOR054c strong similarity to SIS2 protein and C.

tropicalis hal3 proteinYBR067c TIP1 temp.shock induced protein of the

Srp1p/Tip1p familyYGR144w THI4 thiamine-repressed proteinYBL093c ROX3 transcription factorYGL181w GTS1 transcription factor of the


familyYHR206w SKN7 transcription factor with similarity to Hsf1pYKL062w MSN4 transcriptional activatorYML007w YAP1 transcriptional activator involved in

oxidative stress responseYIL147c SLN1 two-component signal transducerYLR006c SSK1 two-component signal transducerYJL128c PBS2 tyrosine protein kinase of the MAP kinase

kinase familyYLL039c UBI4 ubiquitin YMR022w QRI8 ubiquitin-conjugating enzymeYBR082c UBC4 ubiquitin-conjugating enzyme

YDR059c UBC5 ubiquitin-conjugating enzymeYER125w RSP5 ubiquitin-protein ligaseYKL210w UBA1 ubiquitin-protein ligase

DNA repair (direct repair, base excision repairand nucleotide excision repair)

YER142c MAG1 3-methyladenine DNA glycosylaseYML060w OGG1 8-oxoguanine DNA glycosylaseYKL114c APN1 AP endonucleaseYJL092w HPR5 ATP-dependent DNA helicaseYPL204w HRR25 casein kinase I, ser/thr/tyr protein kinaseYPL022w RAD1 component of the nucleotide excision

repairosomeYDL108w KIN28 cyclin-dependent ser/thr protein kinaseYOR386w PHR1 deoxyribodipyrimidine photo-lyaseYOR368w RAD17 DNA damage checkpoint control proteinYER176w DNA dependent ATPase/DNA helicase BYLR032w RAD5 DNA helicaseYIL143c SSL2 DNA helicaseYML061c PIF1 DNA helicase involved in mitochondrial

DNA repair and telomere lengthYER171w RAD3 DNA helicase/ATPaseYDL164c CDC9 DNA ligaseYEL019c MMS21 DNA repair proteinYAL015c NTG1 DNA repair proteinYMR137c PSO2 DNA repair proteinYML095c RAD10 DNA repair proteinYCR066w RAD18 DNA repair proteinYER095w RAD51 DNA repair proteinYDR076w RAD55 DNA repair proteinYDR004w RAD57 DNA repair proteinYOR346w REV1 DNA repair proteinYDR369c XRS2 DNA repair proteinYGL163c RAD54 DNA-dependent ATPase of the Snf2p

familyYDL102w CDC2 DNA-directed DNA polymerase δ,

catalytic 125K subunitYFR023w PES4 DNA-directed DNA polymerase ε

suppressorYNL262w POL2 DNA-directed DNA polymerase ε, catalytic

subunit AYPL167c REV3 DNA-directed DNA polymerase ζYKR056w RNC1 endo-exonucleaseYOL043c NTG2 endonuclease III-like glycosylase 2YER162c RAD4 excision repair proteinYLR288c MEC3 G2-specific checkpoint proteinYFL014w HSP12 heat-shock proteinYIL128w MMS19 involved in repair and RNA polymerase

transcriptionYMR035w IMP2 mitochondrial inner membrane protease

subunitYKR095w MLP1 myosin-like protein related to Uso1pYMR201c RAD14 nucleotide excision repair proteinYBR114w RAD16 nucleotide excision repair proteinYEL037c RAD23 nucleotide excision repair proteinYJR052w RAD7 nucleotide excision repair proteinYDL200c MGT1 O6-methylguanine DNA repair

methyltransferaseYDL101c DUN1 protein kinaseYML032c RAD52 recombination and DNA repair proteinYIL139c REV7 required for DNA damage induced

mutagenesisYBR073w RDH54 required for meiosisYIL066c RNR3 ribonucleotide reductase, repair inducible

large subunitYPL153c SPK1 ser/thr/tyr protein kinaseYDR061w similarity to E. coli deoxyribodipyrimidine

photolyaseYAL019w FUN30 similarity to helicases of the Snf2/Rad54

familyYLR035c similarity to human mutL protein

homologueYPR056w similarity to human transcription factor

BTF2/TFIIH subunit p34YFR038w strong similarity to mouse lymphocyte

specific helicaseYOR206w strong similarity to Rad4pYGR258c RAD2 structure-specific nuclease of the

nucleotide excision repairosomeYDL088c ASM4 suppressor of temperature-sensitive

mutations in Pol3pYDR311w TFB1 TFIIH subunit (transcription initiation


factor), cyclin C component YLR005w SSL1 TFIIH subunit (transcription initiation

factor), factor BYPL122c TFB2 TFIIH subunit (transcription/repair factor)YDR460w TFB3 TFIIH subunit (transcription/repair factor)YGL058w RAD6 ubiquitin-conjugating enzyme

detoxificaton

YOL052c SPE2 adenosylmethionine decarboxylase YFL050c ALR2 aluminum resistance proteinYML116w ATR1 aminotriazole and 4-nitroquinoline

resistance proteinYNL259c ATX1 antioxidant protein and metal

homeostasis factorYLR398c SKI2 antiviral protein and putative helicaseYKL004w AUR1 aureobasidin-resistance proteinYDR256c CTA1 catalase A, peroxisomalYGR088w CTT1 catalase T, cytosolicYJR104c SOD1 copper-zinc superoxide dismutaseYKR066c CCP1 cytochrome c peroxidase YPR198w SGE1 drug resistance proteinYJL101c GSH1 glutamate-cysteine ligase


gazetteer

YDR513w TTR1 glutaredoxinYPL091w GLR1 glutathione reductase (NADPH)YDR135c YCF1 glutathione S-conjugate transporter,

vacuolarYGR197c SNG1 involved in nitroguanidine resistanceYDL168w SFA1 long-chain alcohol dehydrogenaseYCR023c member of major facilitator superfamily

multidrug-resistance protein family 2YNR055c HOL1 member of major facilitator superfamily

multidrug-resistance protein subfamily 1YHR053c CUP1A metallothioneinYHR055c CUP1B metallothioneinYOR079c ATX2 multicopy suppressor of SOD-linked

defectsYDR011w SNQ2 multidrug resistance proteinYHR042w NCP1 NADPH-cytochrome P450 reductaseYOR018w ROD1 O-dinitrobenzene,calcium and zinc

resistance proteinYKL064w MNR2 overexpression overcomes manganese

toxicityYOR266w PNT1 pentamidine resistance factorYDR538w PAD1 phenylacrylic acid decarboxylaseYOR153w PDR5 pleiotropic drug resistance proteinYBL005w PDR3 pleiotropic drug resistance regulatory

proteinYGL016w PDR6 pleiotropic drug resistance regulatory

proteinYIL120w similarity to antibiotic resistance proteinsYIL121w similarity to antibiotic resistance proteinsYLR299w similarity to B. subtilis

γ-glutamyltransferaseYHL040c similarity to C. carbonum toxin pumpYHL047c similarity to C. carbonum toxin pumpYBR180w similarity to drug resistance proteinsYDL100c similarity to E. coli arsenical pump-driving

ATPaseYLL015w similarity to metal resistance proteinsYBR293w similarity to multidrug resistance proteinsYGR138c similarity to multidrug resistance proteinsYHR048w similarity to multidrug resistance proteinsYKR103w similarity to multidrug resistance proteinsYKR104w similarity to multidrug resistance proteinsYLL028w similarity to multidrug resistance proteinsYPR156c similarity to multidrug resistance proteinsYOR273c similarity to resistance proteinsYOR251c similarity to thiosulphate

sulphurtransferasesYOR247w similarity to vanadate-sensitive

suppressor Svs1pYJR025c strong similarity to 3-hydroxyanthranilate

3,4-dioxygenaseYOL130w strong similarity to Alr2pYMR279c strong similarity to aminotriazole

resistance proteinYOR378w strong similarity to aminotriazole

resistance proteinYBR008c strong similarity to benomyl/methotrexate

resistance proteinYCL069w strong similarity to drug resistance protein

SGE1YKL026c strong similarity to glutathione peroxidaseYBR244w strong similarity to glutathione

peroxidasesYKL033w-a strong similarity to holacid-

halidohydrolaseYFR022w strong similarity to Rod1pYLR046c strong similarity to Rta1p and Rtm1p

proteinYER185w strong similarity to Rtm1pYKR105c strong similarity to Sge1p and

hypothetical protein YCL069wYJR015w strong similarity to Sng1pYNR070w strong similarity to Snq2pYBL064c strong similarity to thiol-specific

antioxidant enzymeYDR453c strong similarity to thiol-specific

antioxidant proteinYGL254w FZF1 sulphite resistance proteinYPL092w SSU1 sulphite sensitivity proteinYHR008c SOD2 superoxide dismutase (Mn), mitochondrialYOR031w CRS5 suppressor of cup1 deletion,

metallothionein-like proteinYML028w TSA1 thiol-specific antioxidantYLR043c TRX1 thioredoxin IYGR209c TRX2 thioredoxin IIYGL013c PDR1 transcription factorYMR043w MCM1 transcription factor of the MADS box

familyYDR423c CAD1 transcriptional activatorYPL163c SVS1 vanadate sensitive suppressorYLL060c weak similarity to glutathione transferaseYMR243c ZRC1 zinc- and cadmium resistance protein

ddeettooxxiiffiiccaattiioonn iinnvvoollvviinngg ccyyttoocchhrroommee PP445500YMR015c ERG5 C-22 sterol desaturaseYDR402c DIT2 cytochrome P450 56YHR007c ERG11 cytochrome P450 lanosterol 14a-

demethylaseYLL057c similarity to E. coli dioxygenaseYDR403w DIT1 spore wall maturation protein

cell death and ageing

YOR101w RAS1 GTP-binding proteinYNL098c RAS2 GTP-binding proteinYOL025w LAG2 involved in determining longevityYJL116c NCA3 involved in regulation of synthesis of

Atp6p and Atp8p

YNL066w SUN4 involved in the ageing processYKR042w UTH1 involved in the ageing processYHL003c LAG1 longevity-assurance proteinYER167w BCK2 ser/thr protein kinase of the protein

kinase C pathwayYDR227w SIR4 silencing regulatory proteinYKL008c strong similarity to Lag1pYIL123w strong similarity to Sun4p,Nca3p

degradation of exogenous polynucleotides

YGL213c SKI8 antiviral protein of the β-transducin (WD-40) repeat family

other cell-rescue activities

YPR189w SKI3 antiviral proteinYJR069c HAM1 controls 6-N-hydroxylaminopurine

sensitivity and mutagenesisYGR213c RTA1 involved in 7-aminocholesterol resistanceYKL110c KTI12 involved in resistance to K. lactis killer

toxinYER076c similarity to killer toxin Khr1pYER187w similarity to killer toxin KHS

Unclassified proteinsYEL052w AFG1 ATPase family geneYDR184c BAT1 binds Aip3pYCR072c β-transducin family (WD-40 repeat) proteinYLR459w CDC91 cell division control proteinYJL079c PRY1 contains homology to the plant PR-1

class of pathogen related proteinsYKR013w PRY2 contains homology to the plant PR-1

class of pathogen related proteinsYJL078c PRY3 contains homology to the plant PR-1

class of pathogen related proteinsYOR302w CPA1-l CPA1 leader peptideYML113w DAT1 datin, oligo(dA)/oligo(dT)-binding proteinYKL020c SPT23 dosage-dependent suppressor of Ty-

induced promotor mutationsYJL168c EZL1 enhancer of zeste-likeYOR123c LEO1 extremely hydrophilic proteinYLL065w GIN11 growth inhibitory proteinYDL213c has an RNA recognition domain in the N-

terminal regionYDR505c PSP1 high copy suppressor of ts of mutations

in DNA polymerase αYNL087w homology to YOR086cYLR161w identical to hypothetical proteins YLR156w

and YLR161wYLR156w identical to hypothetical proteins YLR159w

and YLR161wYLR159w identical to hypothetical proteins YLR161w

and YLR156wYHR212c identical with hypothetical protein

YAR060cYHR214w identical with hypothetical protein

YAR066wYAR066w identical with hypothetical protein YIL169cYCR020c-a MAK31 involved in stability of L-A dsRNA-

containing particlesYPL049c DIG1 MAP kinase-associated protein, down-

regulator of invasive growthYKL034w member of Kazal serine protease

inhibitors familyYLR397c AFG2 member of the Sec18p, Pas1p, Cdc48p,

TBP-1 family of ATPasesYCR007c member of the YBR302c familyYGL036w MTC2 Mtf1 two hybrid clone 2YMR200w ROT1 mutant suppresses tor2 mutationYAL059w SIM1 mutants are hypersensitive to calcofluor

whiteYCR019w MAK32 necessary for structural stability of L-A

dsRNA-containing particlesYNL061w NOP2 nucleolar proteinYFR011c ochre suppressor tyr-tRNAYLR196w PWP1 periodic tryptophan proteinYDL235c YPD1 phosphorelay intermediate between Sln1p

and Ssk1pYOR014w RTS1 potential regulatory subunit of protein

phosphatase 2AYOR181w LAS17 proline-rich proteinYER129w PAK1 protein kinaseYOR223w protein of unknown functionYHR093w AHT1 protein of unknown functionYDL167c ARP1 protein of unknown functionYHR191c CTF8 protein of unknown functionYAL008w FUN14 protein of unknown functionYAR002w FUN17 protein of unknown functionYAR014c FUN2 protein of unknown functionYAL031c FUN21 protein of unknown functionYAL014c FUN34 protein of unknown functionYAR008w FUN4 protein of unknown functionYAL033w FUN53 protein of unknown functionYDL234c GYP7 protein of unknown functionYPL054w LEE1 protein of unknown functionYDR335w MSN5 protein of unknown functionYIR006c PAN1 protein of unknown functionYDL105w QRI2 protein of unknown functionYLR204w QRI5 protein of unknown functionYLL003w SFI1 protein of unknown functionYDR350c TCM10 protein of unknown functionYDL169c UGX2 protein of unknown functionYJR050w UTR3 protein of unknown functionYEL035c UTR5 protein of unknown function

YJR067c YAE1 protein of unknown functionYGR172c YIP1 protein of unknown functionYNL044w YIP3 protein of unknown functionYBR111c YSA1 protein of unknown functionYGR123c PPT1 protein ser/thr phosphataseYDL230w PTP1 protein tyrosine phosphataseYER075c PTP3 protein tyrosine phosphataseYPR073c LTP1 protein-tyrosine-phosphataseYNL128w putative phosphataseYCL039w regulatory protein of the β-transducin

familyYJR055w HIT1 required for growth at high temperatureYNL085w MKT1 required for propagation of M2 dsRNA

satellite of L-A virusYLL046c RNP1 ribonucleoproteinYOR046c DBP5 RNA helicaseYDR466w ser/thr protein kinaseYDR490c ser/thr protein kinaseYGL179c ser/thr protein kinaseYGL180w ser/thr protein kinaseYKL168c ser/thr protein kinaseYKL171w ser/thr protein kinaseYLR063w ser/thr protein kinaseYMR291w ser/thr protein kinaseYNL161w ser/thr protein kinaseYOL045w ser/thr protein kinaseYOL100w ser/thr protein kinaseYAR018c KIN3 ser/thr protein kinaseYOR233w KIN4 ser/thr protein kinaseYCR091w KIN82 ser/thr protein kinaseYLL019c KNS1 ser/thr protein kinaseYHR082c KSP1 ser/thr protein kinaseYDL079c MRK1 ser/thr protein kinaseYOR267c ser/thr protein kinase with similarity to

Npr1pYMR216c ser/thr protein kinase with similarity to S.

pombe dsk1YKL116c ser/thr protein kinase with similarity to S.

pombe nim1 proteinYBL056w PTC3 ser/thr protein phosphatase PP2CYDR507c GIN4 ser/thr-protein kinaseYKL126w YPK1 ser/thr-specific protein kinaseYOR007c similarities to protein phosphatasesYOR119c RIO1 similarity to a C. elegans ZK632.3 proteinYLR405w similarity to A. brasilense nifR3 proteinYML079w similarity to A. brasilense nifR3 proteinYML080w similarity to A. brasilense nifR3 proteinYDR205w similarity to A. eutrophus cation efflux

system membrane protein czcD, rat zinctransport protein ZnT-1 and Cot1p

YDL228c similarity to A. klebsiana glutamatedehydrogenase

YLL005c similarity to A. thaliana hyp1 proteinYMR266w similarity to A. thaliana hyp1 proteinYOL084w similarity to A. thaliana hyp1 proteinYNL317w similarity to A. thaliana PRL1 proteinYOL105c similarity to a-agglutinin core protein

AGA1 and mucin proteinsYPL252c similarity to adrenodoxin and ferrodoxinYMR110c similarity to aldehyde dehydrogenaseYIL112w similarity to ankyrin and coiled-coil

proteinsYLR064w similarity to Anopheles NADH-ubiquinone

oxidoreductase, subunit 4YMR153w similarity to Asm4pYDR349c similarity to aspartyl proteasesYDR072c similarity to Aur1pYMR305c similarity to B. japonicum putative β-(-6)

glucan transferaseYDR291w similarity to B. subtilis helicasesYPR201w similarity to B. subtilis hypothetical proteinYPR002w similarity to B. subtilis mmgE proteinYPL258c similarity to B. subtilis transcriptional

activator tenA, and strong similarity tohypothetical proteins YOL055c andYPR121w

YPR121w similarity to B. subtilis transcriptionalactivator tenA, strong similarity tohypothetical proteins YPL258c andYOL055c

YIL159w similarity to BNI1 proteinYDL119c similarity to bovine Graves disease carrier

proteinYNR068c similarity to Bul1pYNL218w similarity to C. burnetii trxB, spoIIIE and

serS genesYCR102c similarity to C. carbonum toxD geneYNL134c similarity to C. carbonum toxD geneYJR013w similarity to C. elegans B0491.1 proteinYPR040w similarity to C. elegans C02C2.6 proteinYGR257c similarity to C. elegans C16C10.1YGR054w similarity to C. elegans E04D5.1 proteinYMR012w similarity to C. elegans hypothetical

139.9K protein F55H2.6YLR022c similarity to C. elegans hypothetical

proteinYNL127w similarity to C. elegans hypothetical

proteinYKL095w YJU2 similarity to C. elegans hypothetical

proteinYML014w similarity to C. elegans hypothetical

protein C14B1.5YKL099c similarity to C. elegans hypothetical

protein C16C10.2YEL004w similarity to C. elegans hypothetical

protein C53B4.6YHL030w similarity to C. elegans hypothetical

protein D2045.2


gazetteer

YOL093w similarity to C. elegans hypotheticalprotein F25H8.1

YDL008w similarity to C. elegans hypotheticalprotein F35G12.9

YKL151c similarity to C. elegans hypotheticalprotein R107.2

YDR196c similarity to C. elegans hypotheticalprotein T05G5.5

YJL029c similarity to C. elegans hypotheticalprotein T05G5.8

YNL223w similarity to C. elegans hypotheticalprotein ZK792.1

YOL003c similarity to C. elegans hypotheticalprotein, YDR126w, YNL326c and YLR246w

YDR049w similarity to C. elegans K06H7.3 proteinYGR278w similarity to C. elegans LET-858YHR004c similarity to C. elegans SPAC2F7.02c

proteinYML059c similarity to C. elegans ZK370.4 proteinYNL168c similarity to C. elegans ZK688.3 protein

and E. coli hpcEpYPR188c similarity to calmodulin and calmodulin-

related proteinsYPR128c similarity to carrier protein FLX1YPL202c similarity to cell size regulation protein

Rcs1pYPR154w similarity to chicken growth factor

receptor-binding protein GRB2 homologueYNL091w similarity to chicken h-caldesmon, Uso1p

and hypothetical protein YKL201cYPL176c similarity to chinese hamster transferrin

receptor proteinYDR259c similarity to Cin5pYGL241w similarity to Cse1pYNL305c similarity to C-term. of A. nidulans

regulatory protein (qutR)YPR127w similarity to C-term. of N. tabacum auxin-

induced proteinYDL112w similarity to C-terminus of human TRP-185

proteinYMR304w similarity to D. melanogaster fat facets

geneYGR003w similarity to D. melanogaster lin19 proteinYLL013c similarity to D. melanogaster pumilio

proteinYNL023c similarity to D. melanogaster shuttle craft

proteinYKL201c similarity to D. melanogaster sperm-tail-

specific proteinYCL001w-a similarity to Dom34pYIL103w similarity to Dph2 proteinYGL018c similarity to E. coli dnaJ homologueYHL014c YLF2 similarity to E. coli GTP-binding proteinYLR011w similarity to E. coli hypothetical 20.4K

proteinYGL037c similarity to E. coli hypothetical 23K

proteinYOR131c similarity to E. coli hypothetical 27K

proteinYDR400w similarity to E. coli hypothetical 33.7K

protein in nfo-frua intergenic regionYDR539w similarity to E. coli hypothetical 55.3K

protein in rfah-rfe intergenic regionYDR332w similarity to E. coli hypothetical proteinYGR021w similarity to E. coli hypothetical proteinYJL046w similarity to E. coli lipoate-protein ligase AYIL003w similarity to E. coli MRP proteinYOR165w similarity to E. histolytica surface lectinYNR015w SMM1 similarity to E. histolytica nitrogen fixation

regulatory protein-3 homologueYER113c similarity to Emp70pYDR036c similarity to enoyl-CoA hydrataseYOR172w similarity to finger protein YKL222c,

YOR162c and YLR266c, weak similarity totranscription factors

YOR162c similarity to finger proteins YKL222c,YOR162c and YLR266c, weak similarity totranscription factors

YOR338w similarity to FUN19 proteinYLR193c similarity to G. gallus px19YKL054c similarity to glutenin, high molecular

weight subunitYOL132w similarity to glycophospholipid-anchored

surface glycoprotein GAS1YHR168w similarity to GTP-binding proteinsYDL033c similarity to H. influenzae hypothetical

protein HI0174YLL027w similarity to H. influenzae hypothetical

protein HI0376YLR419w similarity to helicasesYMR128w similarity to helicasesYGR271w similarity to Hfm1pYDR080w similarity to human (clone S53) mRNA, 3’

end of cdsYLR051c similarity to human acidic 82K proteinYCR026c similarity to human autotaxin YJL059w YHC3 similarity to human Batten disease-related

protein CLN3YHR099w similarity to human DNA-PKYOL114c similarity to human DS-1 proteinYJR036c similarity to human E6-associated proteinYBR265w similarity to human FVT1 proteinYPL120w similarity to human GT197 (partial ORF)YPR023c similarity to human hypothetical proteinYGL141w similarity to human hypothetical protein 1YPL217c similarity to human hypothetical protein

KIAA0187YJR125c similarity to human KIAA0171 protein

YLR050c similarity to human MAC30 C-terminusYCR071c similarity to human NOF1 proteinYOR001w similarity to human nucleolar 100K

polymyositis-scleroderma proteinYEL016c similarity to human nucleotide

pyrophosphataseYIL153w similarity to human phosphotyrosyl

phosphatase activatorYDR280w similarity to human PM-Scl-75 autoantigenYPR108w similarity to human protein GPS1YLR206w similarity to human protein KIAA0171 and

hypothetical protein YDL161wYNL265c similarity to human protein KIAA0174YGR163w similarity to human ragA proteinYDR096w GIS1 similarity to human retinoblastoma

binding protein 2YDR378c similarity to human Sm protein FYGR112w similarity to human SURF-1 proteinYGR080w similarity to human tyrosine kinase A6YDL060w similarity to hypothetical C. elegans

proteinYDR183w similarity to hypothetical C. elegans

proteinYDR427w similarity to hypothetical C. elegans

proteinYDR473c similarity to hypothetical C. elegans

proteinYER051w similarity to hypothetical C. elegans

proteinYGR145w similarity to hypothetical C. elegans

proteinYGR194c similarity to hypothetical C. elegans

proteinYGR245c similarity to hypothetical C. elegans

proteinYHL010c similarity to hypothetical C. elegans

proteinYJR070c similarity to hypothetical C. elegans

proteinYML094w similarity to hypothetical C. elegans

proteinYMR002w similarity to hypothetical C. elegans

proteinYJR072c similarity to hypothetical C. elegans

protein and YLR243wYOL060c similarity to hypothetical C. elegans

protein M02F4.4YDL097c similarity to hypothetical C. elegans

proteinsYER004w similarity to hypothetical E. coli and C.

elegans proteinsYDL238c similarity to hypothetical E. coli proteinYDR013w similarity to hypothetical human KIAA0186

proteinYDR496c similarity to hypothetical human proteinYDR524c similarity to hypothetical human proteinYHR098c similarity to hypothetical human proteinYOR294w similarity to hypothetical human proteinYOR215c similarity to hypothetical M. xanthus

proteinYDR105c similarity to hypothetical mouse proteinYDL193w similarity to hypothetical N. crassa 32K

proteinYOR324c similarity to hypothetical protein YAL028wYOR371c similarity to hypothetical protein YAL056wYJR115w similarity to hypothetical protein YBL043wYER093c-a similarity to hypothetical protein YBL059wYPR030w similarity to hypothetical protein YBL101cYMR101c similarity to hypothetical protein YBR002cYGR066c similarity to hypothetical protein YBR105cYJL171c similarity to hypothetical protein YBR162cYER145c similarity to hypothetical protein YBR207wYLR387c similarity to hypothetical protein YBR267wYJL048c similarity to hypothetical protein YBR273cYFR044c similarity to hypothetical protein YBR281cYDL177c similarity to hypothetical protein YCR059cYDR282c similarity to hypothetical protein YDL001w,

YFR048w and S. pombe hypotheticalprotein SPAC12G12.14

YDR425w similarity to hypothetical protein YDL113cYLR426w similarity to hypothetical protein YDL114wYJL151c similarity to hypothetical protein YDL123wYDR233c similarity to hypothetical protein YDL204wYER139c similarity to hypothetical protein YDR066cYNL249c MPA43 similarity to hypothetical protein YDR109cYLR099c similarity to hypothetical protein YDR125cYJL149w similarity to hypothetical protein YDR131cYLR238w similarity to hypothetical protein YDR200cYDL204w similarity to hypothetical protein YDR233cYHR061c similarity to hypothetical protein YDR309cYHR080c similarity to hypothetical protein YDR326c,

YFL042c and YLR072wYOR012w similarity to hypothetical protein YDR391cYDL113c similarity to hypothetical protein YDR425wYML018c similarity to hypothetical protein YDR438wYML033w similarity to hypothetical protein YDR458cYML034w similarity to hypothetical protein YDR458cYOR019w similarity to hypothetical protein YDR474cYLR183c similarity to hypothetical protein YDR501wYCL036w similarity to hypothetical protein YDR514cYNR027w similarity to hypothetical protein YEL029cYGL197w similarity to hypothetical protein YER132cYDR066c similarity to hypothetical protein YER139cYBR207w similarity to hypothetical protein YER145cYHR209w similarity to hypothetical protein YER175cYGL262w similarity to hypothetical protein YER187w

and killer toxin KHS YPL100w similarity to hypothetical protein YFR021w

YGL228w similarity to hypothetical protein YFR039cYBR281c similarity to hypothetical protein YFR044cYDL001w similarity to hypothetical protein YFR048w,

YDR282c and S. pombe hypotheticalprotein SPAC12G12.14

YPL216w similarity to hypothetical protein YGL133wYPL219w similarity to hypothetical protein YGL134wYDR444w similarity to hypothetical protein YGL144c

and YDL1009cYLR047c similarity to hypothetical protein YGL160wYER132c similarity to hypothetical protein YGL197wYFR039c similarity to hypothetical protein YGL228wYHR036w similarity to hypothetical protein YGL247wYGR031w similarity to hypothetical protein YGR015cYGR015c similarity to hypothetical protein YGR031wYBR105c similarity to hypothetical protein YGR066cYLR373c similarity to hypothetical protein YGR071cYPR158w similarity to hypothetical protein YGR142wYHR149c similarity to hypothetical protein YGR221cYHR158c similarity to hypothetical protein YGR238cYMR295c similarity to hypothetical protein YGR273cYMR310c similarity to hypothetical protein YGR283cYDR338c similarity to hypothetical protein YHR032wYGL247w similarity to hypothetical protein YHR036wYDR309c similarity to hypothetical protein YHR061cYNL075w similarity to hypothetical protein YHR088wYDR348c similarity to hypothetical protein YHR097cYNL144c similarity to hypothetical protein YHR131cYNL156c similarity to hypothetical protein YHR133cYGR221c similarity to hypothetical protein YHR149cYOR147w similarity to hypothetical protein YHR194wYER175c similarity to hypothetical protein YHR209wYJR108w similarity to hypothetical protein YIL015c-aYER064c similarity to hypothetical protein YIL056wYLR036c similarity to hypothetical protein YIL089wYFL034c-b similarity to hypothetical protein YIL106wYNL058c similarity to hypothetical protein YIL117cYNL074c YMK1 similarity to hypothetical protein YIL135cYKR100c similarity to hypothetical protein YIL158wYKR015c similarity to hypothetical protein YJL043wYBR273c similarity to hypothetical protein YJL048cYLL031c similarity to hypothetical protein YJL062wYKR010c similarity to hypothetical protein YJL076wYKR019c similarity to hypothetical protein YJL083wYKR029c similarity to hypothetical protein YJL105pYDR131c similarity to hypothetical protein YJL149wYDL123w similarity to hypothetical protein YJL151cYBR162c similarity to hypothetical protein YJL171cYJR030c similarity to hypothetical protein YJL181wYJL181w similarity to hypothetical protein YJR030cYPR114w similarity to hypothetical protein YJR116wYKL002w similarity to hypothetical protein YKL041wYMR031c similarity to hypothetical protein YKL050c

and human restinYMR086w similarity to hypothetical protein YKL105cYMR171c similarity to hypothetical protein YKL124wYMR115w similarity to hypothetical protein YKL133cYNL101w similarity to hypothetical protein YKL146wYJL076w similarity to hypothetical protein YKR010cYJL043w similarity to hypothetical protein YKR015cYJL083w similarity to hypothetical protein YKR019cYJL105w similarity to hypothetical protein YKR029cYIL158w similarity to hypothetical protein YKR100cYLR019w similarity to hypothetical protein YLL010cYNL328c similarity to hypothetical protein YLR008cYPL063w similarity to hypothetical protein YLR019w

and S. pombe hypothetical proteinSPAC2F7.02c

YIL089w similarity to hypothetical protein YLR036cYLL023c similarity to hypothetical protein YLR064wYFL043c similarity to hypothetical protein YLR072wYNR067c similarity to hypothetical protein YLR144cYDR501w similarity to hypothetical protein YLR183cYNL278w similarity to hypothetical protein YLR187wYDR200c similarity to hypothetical protein YLR238wYOR262w similarity to hypothetical protein YLR243wYDR126w similarity to hypothetical protein YLR246w

and YOL003cYOR137c similarity to hypothetical protein YLR361cYGR071c similarity to hypothetical protein YLR373cYPR117w similarity to hypothetical protein YLR454wYDR458c similarity to hypothetical protein YML034wYJR054w similarity to hypothetical protein YML047cYPL184c similarity to hypothetical protein YML117wYKL050c similarity to hypothetical protein YMR031cYKL105c similarity to hypothetical protein

YMR086wYKL133c similarity to hypothetical protein YMR115wYNL008c similarity to hypothetical protein YMR119wYLR031w similarity to hypothetical protein YMR124wYPL228w similarity to hypothetical protein YMR180cYML118w similarity to hypothetical protein YMR285cYGR273c similarity to hypothetical protein YMR295cYGR283c similarity to hypothetical protein YMR310cYMR119w similarity to hypothetical protein YNL008cYIL117c similarity to hypothetical protein YNL058cYHR088w similarity to hypothetical protein YNL075wYHR131c similarity to hypothetical protein YNL144cYHR133c similarity to hypothetical protein YNL156cYDL211c similarity to hypothetical protein YNL176cYLR187w similarity to hypothetical protein YNL278wYDR214w similarity to hypothetical protein YNL281wYLR008c similarity to hypothetical protein YNL328cYEL029c similarity to hypothetical protein YNR027wYFR012w similarity to hypothetical protein YOL019wYMR063w similarity to hypothetical protein YOL019wYOL083w similarity to hypothetical protein YOL082wYDR474c similarity to hypothetical protein YOR019w


gazetteer

YKR078w similarity to hypothetical protein YOR069wYHR194w similarity to hypothetical protein YOR147wYAL028w similarity to hypothetical protein YOR324cYLR361c similarity to hypothetical protein

YOR3329cYAL034c FUN19 similarity to hypothetical protein YOR338wYAL056w similarity to hypothetical protein YOR371cYFR021w similarity to hypothetical protein YPL100wYML117w similarity to hypothetical protein YPL184cYGL133w similarity to hypothetical protein YPL216wYGL134w similarity to hypothetical protein YPL219wYMR180c similarity to hypothetical protein YPL228wYMR181c similarity to hypothetical protein YPL229wYJR116w similarity to hypothetical protein YPR114wYLR454w similarity to hypothetical protein YPR117wYOL027c similarity to hypothetical protein YPR125wYGR142w similarity to hypothetical protein YPR158wYOL048c similarity to hypothetical proteins YAL018c

and YOL047cYOL047c similarity to hypothetical proteins YAL018c

and YOL048cYMR210w similarity to hypothetical proteins YBR177c

and YPL095cYML052w similarity to hypothetical proteins

YDL222c and YNL194cYLR246w similarity to hypothetical proteins

YDR126w, YNL326c and YOL003cYER072w similarity to hypothetical proteins

YFL004w and YPL019cYLR072w similarity to hypothetical proteins

YFL042c, YFL043c, YDR326c andYHR080c

YGL028c similarity to hypothetical proteinsYGR279c and YMR305c

YFL042c similarity to hypothetical proteinsYHR080c, YDR326c and YLR072w

YNL097c similarity to hypothetical proteinsYHR090c and YHR090c

YJR061w similarity to hypothetical proteins YKL200cand YKL201c

YMR313c similarity to hypothetical proteins YKR089cand YOR081c

YOL019w similarity to hypothetical proteinsYMR063w and YFR012w

YPR027c similarity to hypothetical proteins YNL019cand YNL033w

YNL056w similarity to hypothetical proteinsYNL032w and YNL099c

YNL099c similarity to hypothetical proteinsYNL032w, YNL056w and YDR067c

YNL032w similarity to hypothetical proteinsYNL099c, YNL056w and YDR067c

YOL101c similarity to hypothetical proteinsYOL002c and YDR492w

YNL326c similarity to hypothetical proteinsYOL003c, YLR246w and C. eleganshypothetical protein ZK757.1

YML072c similarity to hypothetical proteinsYOR3141c and YNL087w and weaksimilarity to synaptogamines

YLR152c similarity to hypothetical proteinsYOR3165w and YNL095c

YNL165w similarity to hypothetical proteinsYOR385w and YMR316w

YMR316w similarity to hypothetical proteinsYOR385w and YNL165w

YDR083w similarity to hypothetical S. pombe proteinYDR346c similarity to hypothetical S. pombe proteinYGR272c similarity to hypothetical S. pombe proteinYLR241w similarity to hypothetical S. pombe proteinYML005w similarity to hypothetical S. pombe proteinYOL098c similarity to hypothetical S. pombe proteinYOR091w similarity to hypothetical S. pombe protein

D83992_GYOL071w similarity to hypothetical S. pombe protein

SPAC12B10.06cYFR048w similarity to hypothetical S. pombe protein

SPAC12G12.14 and to YDL001w andYDR282c

YOR322c similarity to hypothetical S. pombe proteinSPAC1F12.05

YOR250c similarity to hypothetical S. pombe proteinSPAC22H10.05c

YER143w similarity to hypothetical S. pombe proteinSPAC56F8.08

YDR504c similarity to hypothetical T. brucei proteinYDR223w similarity to Ifh1pYAL035w FUN12 similarity to Ifm1pYOR109w similarity to inositol polyphosphate 5-

phosphatasesYEL013w similarity to intracellular attachement

proteinsYPR042c similarity to Jsn1pYMR226c similarity to ketoreductasesYGR232w similarity to L. mactans α-latroinsectotoxin YER010c similarity to L. pneumophila dlpA proteinYGR210c similarity to M. capricolum hypothetical

protein SGC3YMR095c similarity to M. leprae hisH proteinYBR079c similarity to M. musculus p162 proteinYNL335w similarity to M. verrucaria cyanamide

hydratase, identical to hypothetical proteinYFL061w

YLL034c similarity to mammalian valosinYMR166c similarity to members of the mitochondrial

carrier protein familyYIR041w similarity to members of the Srp1p/Tip1p

family

YNL006w similarity to Met30pYNL293w similarity to Mic1p and human

transforming protein tre-2, and strongsimilarity to hypothetical protein YOL112w

YNR047w similarity to microtubule-associatedser/thr protein kinases

YPL137c similarity to microtubule-interacting proteinMhp1p and to hypothetical proteinYOR227w

YIL151c similarity to mitochondrial aldehydedehydrogenase Ald1p

YGR058w similarity to mouse calcium-bindingprotein

YBL047c similarity to mouse eps15R proteinYLR200w YKE2 similarity to mouse KE2 proteinYIL023c similarity to mouse MHC H-2K/t-w5-linked

ORF YCR033w similarity to mouse nuclear receptor co-

repressor N-CorYER030w similarity to mouse nucleolinYDR060w similarity to mouse putative CCAAT

binding factor 1YBR187w similarity to mouse putative

transmembrane protein FT27YGR284c similarity to mouse Surf-4 proteinYGR127w similarity to mouse T10 proteinYMR192w similarity to mouse Tbc1 proteinYPL249c similarity to mouse Tbc1 proteinYHR181w similarity to mouse TEG-261 proteinYDR109c similarity to MPA43pYDL038c similarity to mucin proteinsYER085c similarity to myosinsYJL112w similarity to N. crassa sulphur controller-2YDR395w similarity to NMD and CSE1 proteinsYPR072w similarity to N-terminal part of Cdc39pYBL024w similarity to nucleolar Nop2pYDR071c similarity to O. aries arylalkylamine

N-acetyltransferaseYOL164w similarity to P. aeruginosa alkyl

sulphataseYMR099c similarity to P. ciliare possible apospory-

associated proteinYNR029c similarity to P. denitrificans cobW proteinYDR472w similarity to P. falciparum 41-2 protein

antigenYNL136w similarity to P. falciparum mature-parasite-

infected erythrocyte surface antigenMESA

YIL010w similarity to P. falciparum merozoite capprotein-1

YLR107w similarity to P. troglodytes prot GORYOL065c similarity to Pie3p and hypothetical

proteins YIL002c YNL047c similarity to probable transcription factor

Ask10p and hypothetical protein YPR115w,and strong similarity to hypotheticalprotein YIL105c

YBR125c similarity to protein phosphatase 2CYNR038w similarity to Prp5pYER150w similarity to putative cell surface

glycoprotein Sed1pYGL099w similarity to putative human GTP-binding

protein HSR1YPR062w similarity to R. corallinus N-ethylammeline

chlorohydrolase trzAYJL055w similarity to R. fascians hypothetical

protein 6YOR191w similarity to RAD5 proteinYGL059w similarity to rat branched-chain α-ketoacid

dehydrogenase kinaseYBR053c similarity to rat regucalcinYDL015c similarity to rat synaptic glycoprotein SC2YDR457w similarity to rat URE-B1YBR028c similarity to ribosomal protein kinasesYLR276c similarity to RNA helicasesYPR112c similarity to RNA-binding proteinsYPR016c similarity to S. acidocaldarius ao2sac

proteinYOL154w similarity to S. fumigata Asp FIIYHR029c similarity to S. lincolnensis lmbX proteinYFL033c similarity to S. pombe cek1

serine/threonine protein kinaseYIL144w similarity to S. pombe hypothetical proteinYKR051w similarity to S. pombe hypothetical proteinYOL087c similarity to S. pombe hypothetical proteinYBR004c similarity to S. pombe hypothetical protein

SPAC18B11.05YKR079c similarity to S. pombe hypothetical protein

SPAC1D4.10YNL308c similarity to S. pombe hypothetical protein

SPAC22G7.05YAL042w FUN9 similarity to S. pombe hypothetical protein

SPAC24B11.08cYNL310c similarity to S. pombe hypothetical protein

SPAC24H6.02cYGR125w similarity to S. pombe hypothetical protein

SPAC24H6.11cYMR075w similarity to S. pombe hypothetical protein

SPAC2F7.07cYDR175c similarity to S. pombe hypothetical protein

SPAC2F7.15YFL047w similarity to S. pombe hypothetical protein

SPAC2F7.18cYLR023c similarity to S. pombe hypothetical protein

SPAC30D11.11YDR180w similarity to S. pombe hypothetical protein

SPAC31A2.05c

YGL164c similarity to S. pombe hypothetical proteinSPAC31A2.10

YPL236c similarity to S. pombe hypothetical proteinSPAC3H1.13

YAL032c FUN20 similarity to S. pombe hypothetical proteinSPAC8A4.06

YEL007w similarity to S. pombe pac2 proteinYLR247c similarity to S. pombe rad8 proteinYJL062w similarity to S. pombe SPAC13G6.3 proteinYHR009c similarity to S. pombe YAM3 proteinYBL051c similarity to S. pombe Z66568_C proteinYOR240w similarity to S. pombe ZK1058.5 proteinYPL150w similarity to ser/thr kinasesYGR052w similarity to ser/thr protein kinasesYAL017w FUN31 similarity to ser/thr protein kinasesYOR090c similarity to ser/thr protein phosphatasesYBR059c similarity to ser/thr-specific protein kinase

Pak1pYBR274w similarity to ser/thr-specific protein

kinasesYLR118c similarity to several esterasesYMR077c similarity to SNF7 proteinYLR313c similarity to SPA2 proteinYIR033w similarity to Spt23pYBL109w similarity to subtelomeric encoded

proteinsYEL074w similarity to subtelomeric encoded

proteinsYGL263w similarity to subtelomeric encoded

proteinsYHL042w similarity to subtelomeric encoded



proteinsYIL177c similarity to subtelomeric encoded

proteinsYKL219w similarity to subtelomeric encoded

proteinsYMR326c similarity to subtelomeric encoded

proteinsYLR177w similarity to suppressor protein Gin5pYNL191w similarity to Synechocystis hypothetical

proteinYGR036c similarity to T. denticola phosphataseYDR485c similarity to trichohyalinYOR195w similarity to USO1 proteinYPL188w POS5 similarity to Utr1p and hypothetical protein

YEL041wYLR213c similarity to UTR2 proteinYGR189c similarity to Utr2pYGL220w similarity to V. alginolyticus bolA proteinYGR203w similarity to X. laevis protein-tyrosin-

phosphatase cdc homologue 2 and tohypothetical protein YPR200c

YDR284c similarity to YDR503cYEL003w similarity to Yke2pYIL135c similarity to Ymk1pYOL082w similarity to YOL083wYDR534c similarity to YOR383c,Sta1p and pig

mucinYBL101c similarity to YPR030wYCR062w similarity to Ytp1p proteinYFR024c-a strong similarity hypothetical protein

YHR016cYPL151c strong similarity to A. thaliana PRL1 and

PRL2 proteinsYOR034c strong similarity to Akr1pYOR374w strong similarity to aldehyde

dehydrogenaseYIL113w strong similarity to C. albicans dual-

specificity phosphatase MSG5YLR460c strong similarity to C. carbonum toxD

proteinYKL013c strong similarity to C. elegans

hypothetical proteinYNL288w strong similarity to C. elegans

hypothetical proteinYOL077c strong similarity to C. elegans K12H4.3

proteinYGL080w strong similarity to C. elegans R07E5.13

proteinYPR194c strong similarity to C-term. of S. pombe

isp4 proteinYAR023c strong similarity to Fun55p, Fun59p,

YGL051w, YCR007c, YGL053w, YAR031wand YAR028w

YAR028w strong similarity to Fun55p, YGL053w,YCR007c, YAR031w, Fun59p and YGL051w

YGL051w strong similarity to Fun59pYGL236c strong similarity to gidA E. coli proteinYAL036c FUN11 strong similarity to GTP-binding proteinsYMR290c strong similarity to helicases of the

DEAD/DEAH box familyYDR276c strong similarity to Hordeum blt101 proteinYDL103c QRI1 strong similarity to human AgX-1 antigenYDR373w strong similarity to human BDR-1 protein

and other calcium binding proteinsYNR053c strong similarity to human breast tumor

associated autoantigenYDL120w strong similarity to human frataxin

(Friedreichs ataxia)YGR173w strong similarity to human GTP-binding

proteinYKL056c strong similarity to human IgE-dependent

histamine-releasing factor


gazetteer

YPL152w strong similarity to human phosphotyrosylphosphatase activator

YPR028w strong similarity to human protein TB2YCL059c strong similarity to human Rev interacting

protein Rip-1YLR146c strong similarity to human spermidine

synthaseYNL200c strong similarity to human TGR-CL10CYBL036c strong similarity to hypothetical

C. elegans proteinYBL078c strong similarity to hypothetical

C. elegans proteinYMR292w strong similarity to hypothetical

C. elegans proteinYDR430c strong similarity to hypothetical

C. perfringens proteinYOR365c strong similarity to hypothetical protein

YAL053wYHR214w-a strong similarity to hypothetical protein

YAR068wYPR032w strong similarity to hypothetical protein

YBL106cYDR003w strong similarity to hypothetical protein

YBR005wYDR210w strong similarity to hypothetical protein

YBR016wYDL012c strong similarity to hypothetical protein

YBR016w and YDR210wYDR018c strong similarity to hypothetical protein

YBR042cYOL092w strong similarity to hypothetical protein

YBR147wYPL095c strong similarity to hypothetical protein

YBR177cYPL087w strong similarity to hypothetical protein

YBR183wYGL056c strong similarity to hypothetical protein

YBR214wYGL060w strong similarity to hypothetical protein

YBR216cYGL107c strong similarity to hypothetical protein

YBR238cYGL101w strong similarity to hypothetical protein

YBR242wYJL058c strong similarity to hypothetical protein

YBR270cYGR293c strong similarity to hypothetical protein

YBR300cYDR514c strong similarity to hypothetical protein

YCL036wYGL144c strong similarity to hypothetical protein

YDL109cYIL079c strong similarity to hypothetical protein

YDL175cYNL194c strong similarity to hypothetical protein

YDL222c and similarity to hypotheticalprotein YML052w

YBR005w strong similarity to hypothetical proteinYDR003w

YBR042c strong similarity to hypothetical proteinYDR018c

YLR108c strong similarity to hypothetical proteinYDR132c

YPL235w strong similarity to hypothetical proteinYDR190c

YNL281w strong similarity to hypothetical proteinYDR214w

YLR225c strong similarity to hypothetical proteinYDR222w

YHR032w ERC1 strong similarity to hypothetical proteinYDR338c

YHR097c strong similarity to hypothetical proteinYDR348c

YHR108w strong similarity to hypothetical proteinYDR358w

YOR013w strong similarity to hypothetical proteinYDR391c

YJR133w strong similarity to hypothetical proteinYDR399w

YOL002c strong similarity to hypothetical proteinYDR492w

YOR383c strong similarity to hypothetical proteinYDR534c and similarity to L. mexicanasecreted acid phosphatase 2

YPR193c strong similarity to hypothetical proteinYEL066w

YGL224c strong similarity to hypothetical proteinYER037w

YIL057c strong similarity to hypothetical proteinYER067w

YPL019c strong similarity to hypothetical proteinYFL004w

YMR096w strong similarity to hypothetical proteinYFL059w, YNL333w, and Para rubber treeethylene-responsive protein 1

YHR016c YSC84 strong similarity to hypothetical proteinYFR024c-a

YBR214w strong similarity to hypothetical proteinYGL056c

YBR216c strong similarity to hypothetical proteinYGL060w

YPL191c strong similarity to hypothetical proteinYGL082w

YPL189w strong similarity to hypothetical proteinYGL084c

YBR242w strong similarity to hypothetical proteinYGL101w

YDL109c strong similarity to hypothetical proteinYGL144c

YER037w strong similarity to hypothetical proteinYGL224c

YOR387c strong similarity to hypothetical proteinYGL258w

YLR324w strong similarity to hypothetical proteinYGR004w




YPL004c strong similarity to hypothetical proteinYGR086c

YPR157w strong similarity to hypothetical proteinYGR141w

YHR162w strong similarity to hypothetical proteinYGR243w

YBR300c strong similarity to hypothetical proteinYGR293c

YHR054c strong similarity to hypothetical proteinYHR056c

YDR358w strong similarity to hypothetical proteinYHR108w

YNL116w strong similarity to hypothetical proteinYHR115c

YGR238c strong similarity to hypothetical proteinYHR158c

YGR243w strong similarity to hypothetical proteinYHR162w



YAR060c strong similarity to hypothetical proteinYHR212c

YAR068w strong similarity to hypothetical proteinYHR214w-a

YPR071w strong similarity to hypothetical proteinYIL029c

YER067w strong similarity to hypothetical proteinYIL057c

YDL175c strong similarity to hypothetical proteinYIL079c

YIL014c-a strong similarity to hypothetical proteinYIL102c

YNL049c strong similarity to hypothetical proteinYIL109c

YOL162w strong similarity to hypothetical proteinYIL166c

YJL038c strong similarity to hypothetical proteinYJL037w

YJL037w strong similarity to hypothetical proteinYJL038c

YBR270c strong similarity to hypothetical proteinYJL058c

YKR018c strong similarity to hypothetical proteinYJL082w

YKR021w strong similarity to hypothetical proteinYJL084c

YKR053c strong similarity to hypothetical proteinYJL134w

YML047c strong similarity to hypothetical proteinYJR054w

YKL200c strong similarity to hypothetical proteinYJR061w

YDR399w strong similarity to hypothetical proteinYJR133w

YMR238w strong similarity to hypothetical proteinYKL046c

YMR040w strong similarity to hypothetical proteinYKL065c

YMR102c strong similarity to hypothetical proteinYKL121w

YLR413w strong similarity to hypothetical proteinYKL187c

YJL082w strong similarity to hypothetical proteinYKR018c

YJL084c strong similarity to hypothetical proteinYKR021w

YJL134w strong similarity to hypothetical proteinYKR053c

YOR081c strong similarity to hypothetical proteinYKR089c

YIR013c strong similarity to hypothetical proteinYLR013w

YLL010c strong similarity to hypothetical proteinYLR019w

YDR125c strong similarity to hypothetical proteinYLR099c



YDL161w strong similarity to hypothetical proteinYLR206w and to human KIAA0171 protein

YDR222w strong similarity to hypothetical proteinYLR225c

YDR213w strong similarity to hypothetical proteinYLR228c

YOR171c strong similarity to hypothetical proteinYLR260w

YOR173w strong similarity to hypothetical proteinYLR270w

YOR180c strong similarity to hypothetical proteinYLR284c

YGR004w strong similarity to hypothetical proteinYLR324w


YGR038w ORM1 strong similarity to hypothetical proteinYLR350w


YKL187c strong similarity to hypothetical proteinYLR413w

YPR172w strong similarity to hypothetical proteinYLR456w

YDR438w strong similarity to hypothetical proteinYML018c

YBR002c strong similarity to hypothetical proteinYMR101c

YKL121w strong similarity to hypothetical proteinYMR102c

YPL224c strong similarity to hypothetical proteinYMR177w

YOR295w strong similarity to hypothetical proteinYMR233w

YKL046c strong similarity to hypothetical proteinYMR238w

YPL264c strong similarity to hypothetical proteinYMR253c

YGR279c strong similarity to hypothetical proteinYMR305c

YOR385w strong similarity to hypothetical proteinYMR316w

YNL034w strong similarity to hypothetical proteinYNL018c

YNL033w strong similarity to hypothetical proteinYNL019c

YNL019c strong similarity to hypothetical proteinYNL033w

YNL018c strong similarity to hypothetical proteinYNL034w

YIL109c strong similarity to hypothetical proteinYNL049c

YOR086c strong similarity to hypothetical proteinYNL087w and weak similarity tosynaptogamines

YOR092w strong similarity to hypothetical proteinYNL095c

YOR110w strong similarity to hypothetical proteinYNL108c

YHR115c strong similarity to hypothetical proteinYNL116w

YDL222c strong similarity to hypothetical proteinYNL194c and similarity to YML052w

YLR144c strong similarity to hypothetical proteinYNR067c

YDR492w strong similarity to hypothetical proteinYOL002c

YPR125w strong similarity to hypothetical proteinYOL027c

YBR147w strong similarity to hypothetical proteinYOL092w

YDR391c strong similarity to hypothetical proteinYOR013w

YAL007c strong similarity to hypothetical proteinYOR016c, similarity to hamster COP-coated vesicle membrane protein

YKR089c strong similarity to hypothetical proteinYOR081c

YNL095c strong similarity to hypothetical proteinYOR092w

YNL108c strong similarity to hypothetical proteinYOR110w

YLR260w strong similarity to hypothetical proteinYOR171c

YLR270w strong similarity to hypothetical proteinYOR173w

YLR284c strong similarity to hypothetical proteinYOR180c

YLR243w strong similarity to hypothetical proteinYOR262w

YMR233w strong similarity to hypothetical proteinYOR295w

YGL258w strong similarity to hypothetical proteinYOR387c

YPL279c strong similarity to hypothetical proteinYOR390w

YGR086c strong similarity to hypothetical proteinYPL004c

YFL004w strong similarity to hypothetical proteinYPL019c

YBR183w strong similarity to hypothetical proteinYPL087w

YBR177c strong similarity to hypothetical proteinYPL095c

YOR227w strong similarity to hypothetical proteinYPL137c and to microtubule-interactingprotein MHP1

YGL084c strong similarity to hypothetical proteinYPL189w

YGL082w strong similarity to hypothetical proteinYPL191c

YGL139w strong similarity to hypothetical proteinYPL221w

YMR177w strong similarity to hypothetical proteinYPL224c

YDR190c strong similarity to hypothetical proteinYPL235w

YMR253c strong similarity to hypothetical proteinYPL264c


gazetteer

YOR390w strong similarity to hypothetical proteinYPL279c

YIL029c strong similarity to hypothetical proteinYPR071w

YDL242w strong similarity to hypothetical proteinYPR079w

YGR141w strong similarity to hypothetical proteinYPR157w

YLR456w strong similarity to hypothetical proteinYPR172w

YEL066w strong similarity to hypothetical proteinYPR193c

YGL053w strong similarity to hypothetical proteinsYAR031, YGL051w, YAR028w,Fun55p andYCR007c

YMR324c strong similarity to hypothetical proteinsYBL108w, YCR103c and YKL223w

YNR048w strong similarity to hypothetical proteinsYCR094w and YNL323w

YNL323w strong similarity to hypothetical proteinsYCR094w and YNR048w

YBR016w strong similarity to hypothetical proteinsYDL012c and YDR210w

YNL334c strong similarity to hypothetical proteinsYFL060c and YMR095c

YPL221w strong similarity to hypothetical proteinsYGL139w and YAL053w

YDR326c strong similarity to hypothetical proteinsYHR080c, YFL042c and YLR072w

YMR251w strong similarity to hypothetical proteinsYKR076w and YGR154c

YGR154c strong similarity to hypothetical proteinsYKR076w and YMR251w

YKR076w strong similarity to hypothetical proteinsYMR251w and YGR154c

YFL060c strong similarity to hypothetical proteinsYNL334c and YMR095c

YCR094w strong similarity to hypothetical proteinsYNR048w and YNL323w

YOR230w strong similarity to hypothetical proteinsYOR229w and YPL139c

YPL139c strong similarity to hypothetical proteinsYOR230w and YOR229w

YOR229w strong similarity to hypothetical proteinsYOR230w and YPL139c

YAL053w strong similarity to hypothetical proteinsYOR365c,YGL139w,YPL221w

YPL280w strong similarity to hypothetical proteinsYOR391c, YMR322c and YDR533c

YMR321c strong similarity to hypothetical proteinsYPL273w and YLL062c

YLL062c strong similarity to hypothetical proteinsYPL273w, weak similarity to M. lepraemetH2 protein

YOR391c strong similarity to hypothetical proteinsYPL280w, YMR322c and YDR533c

YDR533c strong similarity to hypothetical proteinsYPL280w, YOR391c and YMR322c

YMR322c strong similarity to hypothetical proteinsYPL280w, YOR391c and YDR533c

YHR069c strong similarity to hypothetical S. pombeand human proteins

YMR288w strong similarity to hypothetical S. pombeprotein

YER049w strong similarity to hypothetical S. pombeprotein YER049W

YNL240c strong similarity to K. marxianus LET1protein

YBR301w strong similarity to members of theSrp1p/Tip1p family

YGL261c strong similarity to members of theSrp1p/Tip1p family

YGR294w strong similarity to members of theSrp1p/Tip1p family

YIL176c strong similarity to members of theSrp1p/Tip1p family

YKL224c strong similarity to members of theSrp1p/Tip1p family

YLL025w strong similarity to members of theSrp1p/Tip1p family

YLL064c strong similarity to members of theSrp1p/Tip1p family

YLR037c strong similarity to members of theSrp1p/Tip1p family

YMR325w strong similarity to members of theSrp1p/Tip1p family

YOR394w strong similarity to members of theSrp1p/Tip1p family

YEL047c strong similarity to Osm1pYFL059w strong similarity to Para rubber tree

ethylene-responsive protein1YNL333w strong similarity to Para rubber tree

ethylene-responsive protein 1 andidentical to hypothetical protein YFL059w

YNR065c strong similarity to Pep1pYNR066c strong similarity to Pep1pYER089c PTC2 strong similarity to phosphoprotein

phosphatasesYPL141c strong similarity to protein kinase Kin4pYOL128c strong similarity to protein kinase Mck1pYNL020c strong similarity to protein kinase PAK1YJR150c strong similarity to proteins of the

Srp1p/Tip1p familyYDL214c strong similarity to putative protein kinase

NPR1YEL077c strong similarity to putative purine

nucleotide-binding protein YIL177c

YHL017w strong similarity to putativetransmembrane protein PTM1

YHR017w YSC83 strong similarity to S. douglasii YSD83YDL219w strong similarity to S. equisimilis

hypothetical proteinYPL118w strong similarity to S. kluyveri hypothetical

proteinYNR046w strong similarity to S. pombe hypothetical

protein SPAC31A2.02YNL072w strong similarity to S. pombe hypothetical

protein SPAC4G9.02YDR032c strong similarity to S. pombe obr1YOL010w strong similarity to S. pombe

SPAC12G12.06c proteinYOR163w strong similarity to S. pombe SPAC13G6.14

proteinYOR256c strong similarity to secretory protein

SSP134YCL024w strong similarity to ser/thr protein kinase

GNP1YOR310c strong similarity to SIK1 proteinYDR247w strong similarity to Sks1pO7535 strong similarity to subtelomeric encoded

proteinsYAL068c strong similarity to subtelomeric encoded

proteinsYBL108w strong similarity to subtelomeric encoded

proteinsYBL111c strong similarity to subtelomeric encoded



proteinsYBR302c strong similarity to subtelomeric encoded

proteinsYCL073c strong similarity to subtelomeric encoded

proteinsYCR103c strong similarity to subtelomeric encoded

proteinsYDL248w strong similarity to subtelomeric encoded

proteinsYDR542w strong similarity to subtelomeric encoded

proteinsYDR543c strong similarity to subtelomeric encoded

proteinsYDR544c strong similarity to subtelomeric encoded

proteinsYDR545w strong similarity to subtelomeric encoded

proteinsYEL075c strong similarity to subtelomeric encoded

proteinsYEL076c-b strong similarity to subtelomeric encoded

proteinsYER188c-a strong similarity to subtelomeric encoded

proteinsYER189w strong similarity to subtelomeric encoded

proteinsYER190w strong similarity to subtelomeric encoded

proteinsYFL062w strong similarity to subtelomeric encoded

proteinsYFL063w strong similarity to subtelomeric encoded

proteinsYFL064c strong similarity to subtelomeric encoded



proteinsYGL260w strong similarity to subtelomeric encoded

proteinsYGR295c strong similarity to subtelomeric encoded

proteinsYGR296w strong similarity to subtelomeric encoded

proteinsYHL045w strong similarity to subtelomeric encoded

proteinsYHL048w strong similarity to subtelomeric encoded

proteinsYHR217c strong similarity to subtelomeric encoded

proteinsYHR218w-a strong similarity to subtelomeric encoded

proteinsYIR040c strong similarity to subtelomeric encoded

proteinsYJL225c strong similarity to subtelomeric encoded

proteinsYJR161c strong similarity to subtelomeric encoded

proteinsYJR162c strong similarity to subtelomeric encoded

proteinsYKL223w strong similarity to subtelomeric encoded

proteinsYKL225w strong similarity to subtelomeric encoded

proteinsYKR106w strong similarity to subtelomeric encoded

proteinsYLL066c strong similarity to subtelomeric encoded

proteinsYLL067c strong similarity to subtelomeric encoded

proteinsYLR462w strong similarity to subtelomeric encoded

proteinsYLR463c strong similarity to subtelomeric encoded

proteinsYLR464w strong similarity to subtelomeric encoded

proteins

YLR466w strong similarity to subtelomeric encodedproteins

YLR467w strong similarity to subtelomeric encodedproteins

YML132w strong similarity to subtelomeric encodedproteins

YNL336w strong similarity to subtelomeric encodedproteins



YNL339c strong similarity to subtelomeric encodedproteins

YNR077c strong similarity to subtelomeric encodedproteins

YOL158c strong similarity to subtelomeric encodedproteins

YPL282c strong similarity to subtelomeric encodedproteins

YPL283c strong similarity to subtelomeric encodedproteins

YPR202w strong similarity to subtelomeric encodedproteins



YNR075w EDL1 strong similarity to subtelomeric encodedproteins

YER042w strong similarity to transcription factorsand peptide methionine sulphoxidereductases

YJL186w strong similarity to Ttp1pYEL041w strong similarity to Utr1pYCR063w strong similarity to Xenopus G10 and

human edg-2 proteinYAR027w FUN55 strong similarity to YAR028w, YCR007c,

YGL053w, YAR031w, FUN59p andYGL051w

YAR029w FUN57 strong similarity to YAR031w, YGL053w,Fun55p, Fun59p and YGL051w

YAR033w FUN59 strong similarity to YGL051w, YGL053w,YAR031w, Fun55p, YAR028w andYCR007c

YAR031w strong similarity to YGL053w, Fun59p,YGL051w, Fun55p, YAR028w andYCR007c

YIL102c strong similarity to YIL014c-aYBR025c strong similarity to Ylf1pYKL065c strong similarity to YMR040wYOL112w strong similarity to YNL293w, similarity to

Mic1p and human transforming proteintre-2

YBL106c strong similarity to YPR032wYLR045c STU2 suppressor of a cs tubulin mutationYER120w SCS2 suppressor of an inositol auxotrophic and

a choline sensitive mutantYCR044c suppressor of cdc1-1 ts growth defectYGL083w SCY1 suppressor of GTPase mutantYDR510w SMT3 suppressor of mif2 temperature-sensitive

mutationYKL124w SSH4 suppressor of shr3YLR197w SIK1 suppressor of toxicity of Gal4-IKBYOL102c TPT1 tRNA 2’-phosphotransferaseYIL080w Ty3-2 orf C fragmentYBR015c TTP1 type II membrane proteinYBR066c weak similarity to A. niger carbon

catabolite repressor proteinYKL071w weak similarity to A. parasiticus nor-1

proteinYJL126w weak similarity to A. thaliana nitrilase 3YCR079w weak similarity to A. thaliana protein

phosphatase 2CYHR143w weak similarity to a-agglutinin core protein

AGA1YOR353c weak similarity to adenylate cyclasesYER158c weak similarity to Afr1pYBR074w weak similarity to aminopeptidase YYCR051w weak similarity to ankyrinsYNR039c weak similarity to Anopheles

mitochondrial NADH dehydrogenasesubunit 2

YMR152w weak similarity to AST1 and AST2 proteinYJL109c weak similarity to ATPase Drs2pYIR002c weak similarity to ATP-dependent RNA

helicasesYMR211w weak similarity to β tubulinsYEL040w UTR2 weak similarity to B. subtilis 1,3-1,4-—

glucanaseYNL203c weak similarity to B. subtilis

CDPdiacylglycerol-serine O-phosphatidyltransferase

YDR336w weak similarity to B. subtilis hypotheticalprotein X

YOR111w weak similarity to B. subtilis maf proteinYNR074c weak similarity to B. subtilis nitrite

reductase (nirB)YNR004w weak similarity to bovine interferon γYNL022c weak similarity to C. burnetii FMU proteinYGL246c weak similarity to C. elegans dom-3

proteinYKR071c weak similarity to C. elegans hypothetical

proteinYNL207w weak similarity to C. elegans hypothetical

protein ZK632.3YLR242c weak similarity to C. elegans R05H5.5

protein and T. borreli apocytochrome b


gazetteer

YKL037w weak similarity to C. elegans ubc-2protein

YHR012w PEP11 weak similarity to C. elegans Z47357_AZK1128.1

YJR024c weak similarity to C. elegans Z49131_EZC373.5 protein

YBR086c weak similarity to calcium and sodiumchannel proteins

YGR225w weak similarity to Cdc20pYNR051c weak similarity to chicken nucleolinYMR272c weak similarity to cytochrome b5YEL045c weak similarity to cytochrome c oxidase

III of T. brucei kinetoplastYHR142w weak similarity to cytochrome c oxidasesYDL035c weak similarity to D. discoideum protein

tyrosine phosphataseYGL242c weak similarity to D. melanogaster ANK

proteinYPR200c weak similarity to D. melanogaster cdc25

protein, and similarity to hypotheticalprotein YGR203w

YHL041w weak similarity to D. melanogasterhypothetical protein 6

YOR022c weak similarity to D. melanogasterprobable Ca2+ transporter rdgB

YPL229w weak similarity to D. melanogastertranscription factor shn

YGL185c weak similarity to dehydrogenasesYLR222c weak similarity to Dip2pYER041w weak similarity to DNA repair protein

Rad2pYOR032c weak similarity to DNA-binding proteinsYJL162c weak similarity to dnaJ proteinsYBR220c weak similarity to E. coli ampG proteinYNL217w weak similarity to E. coli bis(5’-nucleosyl)-

tetraphosphataseYER126c weak similarity to E. coli colicin NYGL136c weak similarity to E. coli ftsJ proteinYKL094w YJU3 weak similarity to E. coli hypothetical

proteinYMR155w weak similarity to E. coli hypothetical

protein f402YER152c weak similarity to E. coli hypothetical

protein f470YJR019c weak similarity to E. coli thioesterase IIYPR067w weak similarity to F. alni nitrogen fixation

proteinYDR063w weak similarity to glia maturation factor βYCL028w weak similarity to glutenins, high

molecular weight subunitYPL206c weak similarity to glycerophosphoryl

diester phosphodiesterasesYOR272w weak similarity to GTP-binding protein β

subunitsYAL048c weak similarity to GTP-binding proteinsYBR175w weak similarity to GTP-binding proteinsYPL093w weak similarity to GTP-binding proteinsYGL067w weak similarity to H. influenzae

hypothetical proteinYLR165c weak similarity to H. influenzae

hypothetical protein HI0176YLR239c weak similarity to H. influenzae lipoate

biosynthesis protein BYNR062c weak similarity to H. influenzae L-lactate

permease (lctP) homologueYNL176c weak similarity to Hkr1pYBL032w weak similarity to hnRNP complex protein

homologue YBR233wYER033c weak similarity to human BRCA2 early

onset breast cancer geneYIL036w weak similarity to human cAMP responce

element-binding proteinYJL148w weak similarity to human chromatin

assembly factor IYDR030c weak similarity to human CSA proteinYGL243w weak similarity to human double-stranded

RNA adenosine deaminaseYJL091c weak similarity to human G protein-

coupled receptorYER063w weak similarity to human heterogeneous

ribonuclear particle protein UYJR002w weak similarity to human kinesin-related

protein CENP-EYMR029c weak similarity to human nuclear

autoantigenYCL045c weak similarity to human ORFYJL057c weak similarity to human P1/eIF-2a

protein kinaseYNR008w weak similarity to human

phosphatidylcholine-sterol O-acyltransferase

YJL132w weak similarity to human phospholipaseD

YLL037w weak similarity to human platelet-activating factor receptor

YHR090c weak similarity to human retinoblastomabinding protein 2

YOR064c weak similarity to human retinoblastomabinding protein 2

YMR131c weak similarity to human retinoblastoma-binding protein

YLR272c weak similarity to hypothetical humanORF

YDL111c weak similarity to hypothetical humanprotein

YCR059c weak similarity to hypothetical proteinYDL177c

YNR061c weak similarity to hypothetical proteinYDL218w

YOR004w weak similarity to hypothetical proteinYDR339c

YMR010w weak similarity to hypothetical proteinYDR352w

YGR223c weak similarity to hypothetical proteinYFR021w

YGR095c weak similarity to hypothetical proteinYGR195w

YHR160c weak similarity to hypothetical proteinYGR239c

YGR239c weak similarity to hypothetical proteinYHR160c

YMR299c weak similarity to hypothetical proteinYJL062w

YKL041w weak similarity to hypothetical proteinYKL002w

YMR124w weak similarity to hypothetical proteinYLR031w

YPL109c weak similarity to hypothetical proteinYLR253w

YBR168w weak similarity to hypothetical proteinYLR324w

YNR014w weak similarity to hypothetical proteinYMR206w

YER186c weak similarity to hypothetical proteinYMR316w

YJR129c weak similarity to hypothetical proteinYNL024c

YJL016w weak similarity to hypothetical proteinYNL278w and YLR187w

YMR206w weak similarity to hypothetical proteinYNR014w

YDL218w weak similarity to hypothetical proteinYNR061c

YDR339c weak similarity to hypothetical proteinYOR004w

YLR253w weak similarity to hypothetical proteinYPL109c

YPR151c weak similarity to hypothetical proteinYPL159c

YPL159c weak similarity to hypothetical proteinYPR151c

YGR126w weak similarity to hypothetical proteinYPR156c

YLR391w weak similarity to hypothetical proteinsYAR068w and YHR214w-a

YNL024c weak similarity to hypothetical proteinsYBR271w and YJR129c

YAL018c weak similarity to hypothetical proteinsYOL047c and YOL048c

YDR352w weak similarity to hypothetical proteinsYOL092w, YBR147w and YMR010w

YDR517w weak similarity to hypothetical S. pombeprotein

YCR013c weak similarity to M. leprae B1496_F1_41protein

YPL273w weak similarity to M. leprae metH2protein, and strong similarity tohypothetical protein YLL062c

YEL043w weak similarity to Mad1pYBR186w weak similarity to members of

CDC48/PAS1/SEC18 family of ATPasesYFL046w weak similarity to middle part of C.

elegans myosin heavy chain AYOR350c MNE1 weak similarity to mitochondrial L. illustris

cytochrome oxidase IYMR111c weak similarity to MSN1 proteinYMR172w weak similarity to MSN1 proteinYDL223c weak similarity to mucinYJL036w weak similarity to Mvp1pYNL063w weak similarity to Mycoplasma

protoporphyrinogen oxidaseYLR309c IMH1 weak similarity to myosin heavy chainsYBR156c weak similarity to myosinsYAL022c FUN26 weak similarity to Na+/H+ antiporterYDR413c weak similarity to NADH dehydrogenaseYKR030w weak similarity to NADH dehydrogenasesYPR174c weak similarity to Nbp1pYKR075c weak similarity to negative regulator

Srn1p/Hex2pYCR047c weak similarity to N-methyltransferasesYJL131c weak similarity to non-epidermal Xenopus

keratin, type IYHL024w weak similarity to nuclear protein NOP4YLR126c weak similarity to P. aeruginosa

anthranilate synthase component IIYHL021c weak similarity to P. aeruginosa

γ-butyrobetaine hydroxylaseYMR009w weak similarity to P. aeruginosa

regulatory protein mmsRYGR276c weak similarity to P. troglodytes GOR

proteinYER059w weak similarity to Pho80pYOR281c weak similarity to phosducinsYMR221c weak similarity to photosystem II protein

D2YBR094w weak similarity to pig tubulin-tyrosine

ligaseYOR287c weak similarity to PITSLRE protein kinase

isoformsYBR151w weak similarity to potato sucrose

cleavage proteinYML050w weak similarity to potato sucrose

cleavage proteinYGR262c weak similarity to protein kinasesYPR106w weak similarity to protein kinases

YNR022c weak similarity to protein phosphatasesYBR276c weak similarity to protein-tyrosine-

phosphataseYMR241w weak similarity to putative carrier protein

RIM2YJR044c weak similarity to putative transport

protein YKR103wYBR103w weak similarity to Pwp2pYMR093w weak similarity to Pwp2pYNR064c weak similarity to R. capsulatus bchO

proteinYEL018w weak similarity to Rad50pYGL244w weak similarity to Rad50pYHR022c weak similarity to RAS-related proteinYLR351c weak similarity to rat β-alanine synthaseYCR082w weak similarity to Rbk1pYOR246c weak similarity to reductasesYJL012c weak similarity to regulatory protein

PHO81YDL114w weak similarity to Rhizobium nodulation

protein nodGYGR068c weak similarity to Rod1pYKL107w weak similarity to S. antibioticus probable

oxidoreductaseYER093c weak similarity to S. epidermidis PepB

proteinYMR065w weak similarity to S. pombe hypothetical

protein SPAC13C5.03YGR212w weak similarity to S. pombe hypothetical

protein SPAC18B11.03cYER127w weak similarity to S. pombe hypothetical

protein SPAC18B11.06YBR271w weak similarity to S. pombe uvi22 protein

and hypothetical protein YNL024cYLR311c weak similarity to S. tarentolae

cryptogene protein G4YLR380w weak similarity to Sec14pYNL231c weak similarity to Sec14pYJL123c weak similarity to Sec7pYKL055c weak similarity to short-chain alcohol

dehydrogenasesYNR030w weak similarity to Smp3pYDR486c weak similarity to Snf7pYEL015w weak similarity to Spa2pYHR177w weak similarity to Spombe pac2 proteinYBR155w weak similarity to stress-induced Sti1pYJR101w weak similarity to superoxide dismutasesYBR099c weak similarity to T. brucei mitochondrion

hypothetical protein 6YJL145w weak similarity to T. pacificus retinal-

binding proteinYJL204c weak similarity to Tor2pYER045c weak similarity to transcription factor

Sko1pYDR520c weak similarity to transcription factorsYHR063c weak similarity to translational activator

CBS2YGL004c weak similarity to Tup1pYJR046w weak similarity to Xenopus vimentin 4YOL031c weak similarity to Y. lipolytica Sls1 protein YLL056c weak similarity to Y. pseudotuberculosis

CDP-3,6-dideoxy-D-glycero-L-glycero-4-hexulose-5-epimerase

YCL063w weak similarity to yeast translationregulator Gcd6p

YGR110w weak similarity to YLR099c and YDR125cYDR090c weak similarity to Yro2pYIL044c weak similarity to zinc-finger protein GCS1YLR040c weak similartity to hypothetical protein

YIL011wYNL212w weak simlarity to C. cardunculus cypro4

protein


gazetteer

Documents

Yeast genome Gazetteer p35-65wiki.yeastgenome.org/images/e/e7/gazetteer.pdfYIR030c DCG1 involved in nitrogen-catabolite metabolism YBR213w MET8 involved in the expression of PAPS reductase