Upload
others
View
3
Download
0
Embed Size (px)
Citation preview
You Snooze, You Lose
James M. Blum, MD, FCCM
Chief of Critical Care
Emory University Department of Anesthesiology
Medical Director, Emory ECMO Center
Emory University Hospital
Disclosure
• Consultant for CLEW medical
Overview
• Understand the history of post-cardiac surgery sedation
and ventilator management
• Discuss reasons to change from prior practices
• Understand changes to anesthetics that impact the ability
to “fast-track” patients
• Tips and techniques to extubate the challenging patient
• Discuss when the “slow-track” is being on the right-track
Post-cardiac surgery sedation and ventilator management
Post-cardiac surgery sedation and ventilator management
Post-cardiac surgery sedation and ventilator management
Post-cardiac surgery sedation and ventilator management
Post-cardiac surgery sedation and ventilator management
Post-cardiac surgery sedation and ventilator management
Post-cardiac surgery sedation and ventilator management
Post-cardiac surgery sedation and ventilator management
Why were inhalational anesthetics so bad?
Why were inhalational anesthetics so bad?
Myocardial depressants and vasodilators
Why were inhalational anesthetics so bad?
Why were inhalational anesthetics so bad?
Why were inhalational anesthetics so bad?
So we have the perfect storm:
So we have the perfect storm:
Short acting things (inhalational anesthetics) tend to result in worse
outcomes
So we have the perfect storm:
Short acting things tend to result in worse outcomes
Long acting things (opiates) result in better outcomes
So we have the perfect storm:
Short acting things tend to result in worse outcomes
Long acting things result in better outcomes
All it takes is some mechanical ventilation and we should be fine!
There is only one problem
There is only one problem
Awareness
There is only one problem
Awareness
There is only one problem
3% - 10%
How do we deal with this?
How do we deal with this?
Benzodiazepines
What’s the problem with this combination?
What’s the problem with this combination?
Benzodiazepines
What’s the problem with this combination?
Benzodiazepines + Opiates =
What’s the problem with this combination?
Benzodiazepines + Opiates = Synergistic Sedation
Reasons to Change Practice and Try to Wake Early
Reasons to Change Practice and Try to Wake Early
better for patients
Reasons to Change Practice and Try to Wake Early
better for patients
-DVT
Reasons to Change Practice and Try to Wake Early
better for patients
-DVT
-pneumonia
Reasons to Change Practice and Try to Wake Early
better for patients
-DVT
-pneumonia
-pressure ulcers
Reasons to Change Practice and Try to Wake Early
better for patients
-DVT
-pneumonia
-pressure ulcers
-stress ulcers
These do not happen overnight
Reasons to Change Practice and Try to Wake Early
better for patients
-DVT
-pneumonia
-pressure ulcers
-stress ulcers
one major incentive - $
Reasons to Change Practice and Try to Wake Early
one major incentive - $
Show Me the Money!!!
There is nothing wrong with saving some $
Show Me the Money!!!
EMORY UNIVERSITY HOSPITAL MIDTOWN 550 PEACHTREE ST NE GA - Atlanta $91,988.10 $25,335.59 $23,607.39
DRG 236 - CABG W/O Cath or MCC
https://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trends-and-Reports/Medicare-Provider-Charge-Data/Inpatient2015.html
Show Me the Money!!!
EMORY UNIVERSITY HOSPITAL MIDTOWN 550 PEACHTREE ST NE GA - Atlanta $91,988.10 $25,335.59 $23,607.39
DRG 236 - CABG W/O Cath or MCC
Show Me the Money!!!
EMORY UNIVERSITY HOSPITAL MIDTOWN 550 PEACHTREE ST NE GA - Atlanta $91,988.10 $25,335.59 $23,607.39
DRG 236 - CABG W/O Cath or MCC
Assume OR Costs are fixed
Things you can modify:
Medical supplies
Medications used
Duration of stay
Show Me the Money!!!
EMORY UNIVERSITY HOSPITAL MIDTOWN 550 PEACHTREE ST NE GA - Atlanta $91,988.10 $25,335.59 $23,607.39
DRG 236 - CABG W/O Cath or MCC
Assume OR Costs are fixed
Things you can modify:
Medical supplies - $
Medications used - $
Duration of stay - $$$$
MV
What if we use super short acting dope?
What if we use super short acting dope?
What if we use super short acting dope?
What if we use dedicated post-op recovery units?
What if we use dedicated post-op recovery units?
Any model can help you extubate early
Fast-tracking starts in the operating room
Fast-tracking starts in the operating room
Low-dose opiate (fentanyl ≤ 20 μg/kg or equivalent) or short-acting opioid supplemented with propofol or
etomidate, or volatile anaesthesia with or without a protocol for early extubation within eight hours.
Conventional cardiac anaesthesia was defined by the use of high-dose opioids (fentanyl ≥ 20 μg/kg or
equivalent) with propofol or etomidate, or volatile anaesthesia with or without a protocol for extubation
within a specified time after surgery.
Fast-tracking starts in the operating room
Fast-tracking starts in the operating room
Fast-tracking starts in the operating room
How to Fast Track
Change opiate
Reduce opiate dose
Change paralytic
Extubation in OR
Protocolized Extubation
Fast-tracking starts in the operating room
Fast-tracking starts in the operating room
Fast-tracking saves
you 7.4 hours on
the ventilator
Fast-tracking starts in the operating room
Fast-tracking starts in the operating room
Fast-tracking saves
you 4.5 hours in the ICU
How to Fast Track
Change opiate
Reduce opiate dose
Change paralytic
Extubation in OR
Protocolized Extubation
How to Fast Track
Change opiate
Reduce opiate dose
Change paralytic
Extubation in OR
www.extubateme.com
How to Fast Track
Wake
Warm
Whip it Out
Problems Waking
Problems Waking
Physiologic
Pharmacologic
Pathologic
Problems Waking
Physiologic
Problems Waking
Pharmacologic
Problems Waking
Pathologic
Problems waking?…the Workup!
Problems Weaning
Failed ventilator weaning assessment
Failed ventilator weaning assessment
Failed ventilator weaning assessment
Failed ventilator weaning assessment
Failed ventilator weaning assessment
Failed ventilator weaning assessment by protocol?
Failed ventilator weaning assessment
Failed ventilator weaning assessment by protocol?
Go ahead a make a full assessment
Failed ventilator weaning assessment
Failed ventilator weaning assessment by protocol?
Go ahead a make a full assessment
Make a decision
Failed ventilator weaning assessment
Failed ventilator weaning assessment by protocol?
Go ahead a make a full assessment
Make a decision….perhaps with a friend
Failed ventilator weaning assessment
Failed ventilator weaning assessment by protocol?
Go ahead a make a full assessment
Make a decision….perhaps with a friend….and a number of resources
Problems Whipping it Out
Sedation mechanism
Problems Whipping it Out
Sedation Dexmedetomidine vs. Propofol
Sedation Dexmedetomidine vs. Propofol
Sedation Dexmedetomidine vs. Propofol
Sedation Dexmedetomidine vs. Propofol
Sedation Dexmedetomidine vs. Propofol
Sedation Dexmedetomidine vs. Propofol
Sedation Dexmedetomidine vs. Propofol
Sedation Dexmedetomidine vs. Propofol
Reintubation…what to do?
1. Failure of a spontaneous breathing trial, defined as arterial
oxygen saturation (SaO2) less than 90%with 12 L of oxygen
during a T-tube trial or PaO2 less than 75mmHg with a fraction
of inspired oxygen (FIO2) of at least 50% during lowlevel
pressure support
2. Successful spontaneous breathing trial in patients with any
of the following preexisting risk factors for postextubation
acute respiratory failure: body mass index greater than 30,
left ventricular ejection fraction less than 40%, and failure
of previous extubation
3. Successful spontaneous breathing trial followed by failed
extubation, defined as at least 1 of the following: PaO2:FIO2
ratio less than 300, respiratory rate greater than 25/min for
at least 2 hours, and use of accessory respiratory muscles
or paradoxic respiration.
Eligibility
Snatching Defeat from the Jaws of Victory
Concerns about loss of airway
Snatching Defeat from the Jaws of Victory
Concerns about loss of airway
Do not fast-track the difficult airway
Snatching Defeat from the Jaws of Victory
67 yo M s/p elective CABG for CAD
Snatching Defeat from the Jaws of Victory
67 yo M s/p elective CABG for CAD
Intubated using glide scope with difficulty in OR
Snatching Defeat from the Jaws of Victory
67 yo M s/p elective CABG for CAD
Intubated using glide scope with difficulty in OR
Uneventful OR course
Snatching Defeat from the Jaws of Victory
67 yo M s/p elective CABG for CAD
Intubated using glide scope with difficulty in OR
Uneventful OR course
Extubated after 5 hours in ICU after meeting all protocol metrics
Snatching Defeat from the Jaws of Victory
67 yo M s/p elective CABG for CAD
Intubated using glide scope with difficulty in OR
Uneventful OR course
Extubated after 5 hours in ICU after meeting all protocol metrics
Develops respiratory stridor
Snatching Defeat from the Jaws of Victory
67 yo M s/p elective CABG for CAD
Intubated using glide scope with difficulty in OR
Uneventful OR course
Extubated after 5 hours in ICU after meeting all protocol metrics
Develops respiratory stridor
Attempt by APP to reintubate
Snatching Defeat from the Jaws of Victory
67 yo M s/p elective CABG for CAD
Intubated using glide scope with difficulty in OR
Uneventful OR course
Extubated after 5 hours in ICU after meeting all protocol metrics
Develops respiratory stridor
Attempt by APP to reintubate
Failed….Anesthesia called
Snatching Defeat from the Jaws of Victory
67 yo M s/p elective CABG for CAD
Intubated using glide scope with difficulty in OR
Uneventful OR course
Extubated after 5 hours in ICU after meeting all protocol metrics
Develops respiratory stridor
Attempt by APP to reintubate
Failed….Anesthesia called
Difficult bag mask
Snatching Defeat from the Jaws of Victory
67 yo M s/p elective CABG for CAD
Intubated using glide scope with difficulty in OR
Uneventful OR course
Extubated after 5 hours in ICU after meeting all protocol metrics
Develops respiratory stridor
Attempt by APP to reintubate
Failed….Anesthesia called
Difficult bag mask
Cardiac arrest
Snatching Defeat from the Jaws of Victory67 yo M s/p elective CABG for CAD
Intubated using glide scope with difficulty in OR
Uneventful OR course
Extubated after 5 hours in ICU after meeting all protocol metrics
Develops respiratory stridor
Attempt by APP to reintubate
Failed….Anesthesia called
Difficult bag mask
Cardiac arrest
Devastating neurologic injury
Snatching Defeat from the Jaws of Victory
Sometimes the “slow-track” is the right track
Snatching Defeat from the Jaws of Victory
Sometimes the “slow-track” is the right track
Difficult Airway
Snatching Defeat from the Jaws of Victory
Sometimes the “slow-track” is the right track
Difficult Airway
Marginal pulmonary status
Snatching Defeat from the Jaws of Victory
Sometimes the “slow-track” is the right track
Difficult Airway
Marginal pulmonary status
Concerns about bleeding
Snatching Defeat from the Jaws of Victory
Sometimes the “slow-track” is the right track
Difficult Airway
Marginal pulmonary status
Concerns about bleeding
Marginal pulmonary status
High-dose pressors
Conclusions
• Fast-track extubations start in the OR, but require the ICU
team to execute the pivotal move
• Primary reasons for fast-track are financial, but overall
may improve patient care
• Use of pharmacy and high flow NC and NIV can bridge the
failing patient
• Trail of extubation is reasonable in controlled situations
• Don’t be afraid of the "slow-track"