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Yuhong Zhang
276 Grove Street #.8, Newton, MA, 02466, USA
( 617) 953-4904 (cell); [email protected]
EDUCATION AND ACADEMIC DEGREES
1986-1987, M.Sc.training program in Pharmacology, Anhui Medical
University, Hefei, Anhui,
P.R.China ( Pharmacology)
1983, Bachelor of medicine, Xian Medical University, Xian,
Shaanxi, P.R.China ( Pharmacy)
PROFESSIONAL APPOINTMENTS
Research associate in Beth Israel Deaconess Medical Center,
Jul.2007-now
Research fellow, Research associate, in University Texas Medical
Branch. USA 1999-
July.2007
Research administrator in Beijing Biotechnology and New Drugs
Center,1997-1999
Lecturer, research fellow of Pharmacology, in Qinghai Medical
School 1983 -1997
TECHNICAL SKILLS:
My work experience mainly focuses on molecular biology and in
vivo pharmacology area.
In Vivo Pharmacology Work:
Small animal surgery, collection of blood and various tissue
types for ex vivo
analysis( primary cell culture, fix tissue forhistology
work)
Animal injections, dosing by using various routes of
administration (IV, PO,SC, IM, ID, IP)
Animal bleeding, assessment (clinical observations, health
checks, and disease
scoring).
Establishing tumor models in mice and rat by injecting tumor
cells or
performingsubcutaneous (SC) implantfor cancer pharmacology study
Acute, chronic toxicity experiments
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Molecular and Cell Biology:
Real Time PCR
miRNA
Isolation of lymphocytes
RNA,DNA isolation RNase protection assay
Southern blot
Northern blot analysis
Membrane-based cDNA macroarrays
Cell culture (primary cell culture)
Stable transfection
Two-Dimensional Gel Electrophoresis
Immunology, Antibody and Proteins:
Immunohistochemical staining
Elisa assay
Western blot
Laboratory management
Clinical samples collection and shipment
Serum bank and tissue bank maintenance
Data analysis, and familiar with bioinformatics
Order lab supply
Lab equipments maintenance Protocol creating and
modification
Computer Skills
Microsoft Office XP (Word, Excel, PowerPoint, Access).
PUBLICATIONS AND PRESENTATIONS:
Yuhong Zhang et al: Ribavirin Treatment Up-regulates Antiviral
Gene _Expression via theInterferon-Stimulated Response Element in
Respiratory Syncytial Virus-Infected Epithelial
Cells. Journal of Virology, May.2003, p.5933-5947
Yuhong Zhang et al: _Expression of Respiratory Syncytial
Virus-Induced Chemokine
Gene Networks in Lower Airway Epithelial Cells Revealed by cDNA
Microarrays. Journal
of Virology, Oct.2001, p.9044-9058
Daryl Lau, Mala Sinha, Bruce Luxon, Yuhong Zhang et al:
Interferon-induced Gene
Expression in Liver and Peripheral Blood Mononuclear
cells(PBMCs) in HCV Genotype 1
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patients. Abstract on 15th International Symposium on Hepatitis
C Virus & Related
Viruses 2008.
Brasier AR, Spratt H, Wu Z, Boldogh I, Zhang Y, et al: Nuclear
Heat Shock Response
and Novel Nuclear Domain 10 Reorganization in Respiratory
Syncytial Virus-infected
A549 Cells Identified by High-Resolution Two-Dimensional Gel
Electrophoresis. Journal
of Virology, Nov.2004, p.11461-11476 Tian B, Zhang Y, Luxon BA,
Garofalo RP, Casola A, Sinha M, Brasier AR. Identification
of NF-kappaB-dependent gene networks in respiratory syncytial
virus-infected cells.
Jounal of Virology, Jul.2002, p.824-836
Yuhong Zhang et al: Measurement of hair vanadium in patients
with heart, haptic and
renal dysfunction. Journal of Qinghai Medical College
1998,19(1):1
Yuhong Zhang:Anti-HIV effect of Fluoroquinolones. Journal of
Chinese Northwest
Pharmcology 1997,2:88
Yuhong Zhang et al: Measurement of hair vanadium in acute
leukemia. Journal of
Qinghai Medical College 1996,1:18
Yuhong Zhang et al: Development and application of ion pump
inhibitor. Journal of
Qinghai Medicine 1994,5:88
Yuhong Zhang:ACEI is benefit for patients with acute heart
infarction. Journal of Qinghai
Medical College 1993,14(2):122
Textbook:
Advance pharmacology course, 3rd,Shaanxi people's educational
press, 1995 Apply clinic pharmcology,1st, Gansu culture press,
1996
Reference:
Available upon request
