Yvette Garcia, PharmD, BCPS1st Year Executive Administration

Program

Statistics Independent Project: A Pharmacist-Driven Intervention Program

To evaluate whether a pharmacist-driven intervention program affects total pharmacy savingsWithin the past 2 years an antibiotic

stewardship program was implemented at Rio Grande Regional Hospital

Pharmacists are required to make and document medication interventions on a daily basis

Pharmacist-Driven Intervention Program

Monthly total numbers of antibiotic interventions and defined daily doses (DDD) per 1,000 adjusted-patient days (APD)

HypothesisTotal savings=$6984.26 +$113.06 X1 + $5.29

X2 + εX1: antibiotic interventionsX2: DDD/1K APD

Data

Antibiotic Interventions

0 10 20 30 40 50 60 70 80 90 $-

$5,000.00

$10,000.00

$15,000.00

$20,000.00

$25,000.00

R² = 0.480370193575695

Antibiotic Interventions

Antibiotic InterventionsLinear (Antibiotic Interventions)

DDD/1 K APD

650.00 670.00 690.00 710.00 730.00 750.00 770.00 790.00 810.00 830.00 850.00 $4,200.00

$6,200.00

$8,200.00

$10,200.00

$12,200.00

$14,200.00

$16,200.00

$18,200.00

R² = 0.0151304757254525

DDD/1 K APD

DDD/1 K APDLinear (DDD/1 K APD)

70% of variation in savings can be explained by variation in antibiotic interventions and DDD/1 K APD

Regression

Regression StatisticsMultiple R 0.70R Square 0.49Adjusted R Square 0.44Standard Error 2497.50Observations 26

On average each patient has a total savings of $6,984.26 with an additional savings of $113.06 per antibiotic intervention and $5.29 per DDD/1K APD

Regression

ANOVA df SS MS F Significance F

Regression 2 136090232.60 68045116.30 10.91 0.00

Residual 23 143463009.44 6237522.15

Total 25 279553242.04

CoefficientsStandard

Error t Stat P-value Lower 95% Upper 95%Intercept 6984.26 7306.92 0.96 0.35 -8131.26 22099.79

Antibiotic Interventions 113.06 24.59 4.60 0.00 62.19 163.92DDD/1 K APD 5.29 9.85 0.54 0.60 -15.08 25.67

Antibiotic interventions are a significant determinant of total savings

To increase total savings pharmacist should continue to evaluate patients for antibiotic interventions

Conclusion