INTERVENTIONAL TRIALS: A REVIEW Quality of Study Designs | Trends Studies & EnrollmentSource: ClinicalTrials.govData Download Date: December 26, 2016 Publication Date: January 7, 2017Analytical tool: IBM Watson
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Inte
rven
tiona
l tria
ls 187,607 studies
Participants are assigned to receive one or more interventions, or none at all, as assigned in the protocol, so that researchers can evaluate their effects on biomedical or health-related outcomes.
Interventions can be diagnostic, therapeutic, or behavioral.
January 5, 2017
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Prio
rity
Info
rmat
ion
Req
uire
men
ts• How are study designs changing over time? • Is the level of evidence produced improving? • What are the trends in quality parameters of study designs?• Can quality of studies be measured using the available data?
• What are the trends for number of studies? • How trends in number of trials compares to enrollment? • Which interventions are studied the most? • Who are the sponsors of clinical trials? • Where the funding comes from? • What are the main reasons to conduct clinical trials? • What are the endpoints? What are the trends, are they changing? • What is the primary purpose? Are the trends changing? How? • Are the results available? In what form?
INTERVENTIONSDrugs | Biological | Device | Procedure | Radiation Behavioral | Dietary Supplement | Genetic | Other
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by InterventionsNumber of trials Enrolled patients
Behavioral Biological Device Dietary supplement Drug Genetic Other Procedure Radiation
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by InterventionsBreakdown by phase (Number of Studies)
Behavioral Biological Device Dietary supplement Drug Genetic Other Procedure Radiation
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by InterventionsBreakdown by phase (Enrollment)
Behavioral Biological Device Dietary supplement Drug Genetic Other Procedure Radiation
Number of Enrolled Patients: Results skewed by several studies with very high number of subjects including three studies with unlimited number of participants (99,999,999)
Clinical trials by InterventionsTrends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Behavioral Biological Device Dietary supplement Drug Genetic Other Procedure Radiation
PHASESPhase 0 | Phase 1 | Phase 2 | Phase 3 | Phase 4
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by PhasesPhase 0 Phase 1 Phase 1|2 Phase 2 Phase 2|3 Phase 3 Phase 4 Blank
Number of trials Enrolled patients
Phase 0: Exploratory study involving very limited human exposure to the drug (screening, microdose studies).
Phase 1: Studies conducted with healthy volunteers to find most important safety issues see how the drug is metabolized and excreted.
Phase 2: Studies that gather preliminary data on effectiveness. Safety continues to be evaluated.
Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages.
Phase 4: Studies occurring after FDA has approved a drug for marketing to gather additional information about a drug's safety, efficacy, or optimal use.
Clinical trials by PhasesTrends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Phase 0 Phase 1 Phase 1|2 Phase 2 Phase 2|3 Phase 3 Phase 4 Blank
DESIGN: PRIMARY PURPOSEBasic Science | Diagnostic | Educational | Prevention | Screening Health Science Research | Treatment | Supportive Care
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by Primary Purpose
Basic Science Diagnostic Educational/Counseling/TrainingHealth Services Research Prevention Screening Supportive Care Treatment Blank
Number of trials Enrolled patients
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by Primary PurposeBreakdown by phase (Number of Studies)
Basic Science Diagnostic Educational/Counseling/TrainingHealth Services Research Prevention Screening Supportive Care Treatment Blank
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by Primary PurposeBreakdown by phase (Enrollment)
Basic Science Diagnostic Educational/Counseling/TrainingHealth Services Research Prevention Screening Supportive Care Treatment Blank
Number of Enrolled Patients: Results skewed by several studies with very high number of subjects including three studies with unlimited number of participants (99,999,999)
Clinical trials by Primary PurposeTrends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
FUNDINGIndustry | NIH | Other | U.S. Federal AgenciesCombined Funding
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by FundingNumber of trials Enrolled patients
Industry Industry + other entities NIH NIH + other entities Other Other + other entities U.S. Federal Agencies U.S. Fed + other entities
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by FundingBreakdown by phase (Number of Studies)
Industry Industry + other entities NIH NIH + other entities Other Other + other entities U.S. Federal Agencies U.S. Fed + other entities
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by FundingBreakdown by phase (Enrollment)
Industry Industry + other entities NIH NIH + other entities Other Other + other entities U.S. Federal Agencies U.S. Fed + other entities
Number of Enrolled Patients: Results skewed by several studies with very high number of subjects including three studies with unlimited number of participants (99,999,999)
Clinical trials by FundingTrends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Industry Industry + other entities NIH NIH + other entities Other Other + other entities U.S. Federal Agencies U.S. Fed + other entities
DESIGN: ENDPOINT CLASSIFICATION PK/PD | Safety | Efficacy | BA/BE
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by Endpoint ClassificationNumber of trials Enrolled patients
Bio-availability study Bio-equivalence study Efficacy study Pharmaco-dynamic study Pharmaco-kinetic study PK/PD Safety study Safety/Efficacy study Blank
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Bio-availability study Bio-equivalence study Efficacy study Pharmaco-dynamic study Pharmaco-kinetic study PK/PD Safety study Safety/Efficacy study Blank
Clinical trials by Endpoint ClassificationBreakdown by phase (Number of Studies)
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by Endpoint ClassificationBreakdown by phase (Enrollment)
Bio-availability study Bio-equivalence study Efficacy study Pharmaco-dynamic study Pharmaco-kinetic study PK/PD Safety study Safety/Efficacy study Blank
Number of Enrolled Patients: Results skewed by several studies with very high number of subjects including three studies with unlimited number of participants (99,999,999)
Clinical trials by Endpoint Classification Trends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
QUALITY ATTRIBUTESAllocation | Intervention Model | Masking
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
QUALITY of EVIDENCELEVEL I LEVEL II LEVEL III LEVEL IV LEVEL V
High quality randomized trials
Lesser quality RCT Case control study Case series Expert opinion
High quality prospective studies
Prospective or comparative study
Retrospective comparative study
Case control study (diagnostic studies)
Testing previously developed diagnostic criteria on consecutive
patients
Retrospective study, lesser quality
prospective study
Study of non-consecutive patients inconsistently applied
reference gold standard
Poor reference standard
Sensible costs and alternatives
Untreated controls from an RCT
Analyses with no sensitivity analyses.
Values from many studies with multiway sensitivity analyses
Development of diagnostic criteria on consecutive patients,
Analyses based on limited alternatives,
costs & poor estimates
Systematic review of Level I studies
Systematic review of L2 studies or L1 studies
with inconsistent results.
Systematic review of L3 studies.
Source: Elsevier
DESIGN: ALLOCATIONRandomized | Non-Randomized | Single-Arm Trials
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by Allocation Number of trials Enrolled patientsAllocation: A clinical trial
design strategy used to assign participants to an arm of a study.
Randomized Controlled Trial: Participants are assigned to intervention groups by chance
Nonrandomized Trial: Participants are expressly assigned to intervention groups through a non-random method, such as physician choice
Number of Enrolled Patients: Results skewed by three studies with unlimited number of participants (99,999,999)
Non-randomizedRandomized Single arm study
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by AllocationBreakdown by phase (number of studies)
Non-randomizedRandomized Single arm study
Clinical trials by AllocationTrends by Start Date & Completion Date
Non-randomizedRandomized Single arm study
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
DESIGN: INTERVENTION MODELParallel | Cross-Over | Factorial | Single-Group
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by Intervention Model Parallel Study Design: Two or more groups of participants receive different interventions "in parallel“.
Cross-over Study Design: Groups of participants receive two or more interventions in a particular order. So during the trial, participants "cross over" from one drug to the other.
Single Group Study Design: All participants receive the same intervention.
Factorial Study Design: Groups of participants receive one of several combinations of interventions so during the trial, all possible combinations of the two drugs are given to different groups of participants.
Number of trials Enrolled patients
Crossover Factorial Parallel Single Group Blank
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by Intervention Model Breakdown by phase (number of studies)
Crossover Factorial Parallel Single Group Blank
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by Intervention Model Breakdown by phase (Enrollment)
Crossover Factorial Parallel Single Group Blank
Number of Enrolled Patients: Results skewed by several studies with very high number of subjects including three studies with unlimited number of participants (99,999,999)
Clinical trials by Intervention ModelTrends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Crossover Factorial Parallel Single Group Blank
DESIGN: MASKINGDouble-Blind | Single-Blind | Open Label
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by MaskingOpen Label: Describes a clinical trial in which masking is not used, and all parties involved in the trial know which participants have been assigned which interventions.
Single Blind: A type of Masking in which one party involved in the clinical trial, typically the investigator or participants, does not know which participants have been assigned which interventions.
Double Blind: A type of Masking in which two or more parties do not know which participants have been assigned which interventions. Typically, the parties include the investigator and participants, but sometimes also the assessor or caregiver. .
Double Blind Open Label Single Blind Blank
Number of trials Enrolled patients
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by MaskingBreakdown by phase (Number of studies)
Double Blind Open Label Single Blind Blank
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by MaskingBreakdown by phase (Enrollment)
Double Blind Open Label Single Blind Blank
Number of Enrolled Patients: Results skewed by several studies with very high number of subjects including three studies with unlimited number of participants (99,999,999)
Clinical trials by MaskingTrends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Double Blind Open Label Single Blind Blank
RECRUITMENTRecruiting | Enrolling by Invitation |Active, not Recruiting Completed | Suspended | Terminated | Withdrawn
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by RecruitmentNumber of trials Enrolled patients
Active, not recruiting Completed Enrolling by invitation Not yet recruiting Recruiting Suspended Terminated Unknown status Withdrawn
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by RecruitmentBreakdown by phase (Number of Studies)
Active, not recruiting Completed Enrolling by invitation Not yet recruiting Recruiting Suspended Terminated Unknown status Withdrawn
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by RecruitmentBreakdown by phase (Enrollment)
Number of Enrolled Patients: Results skewed by several studies with very high number of subjects including three studies with unlimited number of participants (99,999,999)
Active, not recruiting Completed Enrolling by invitation Not yet recruiting Recruiting Suspended Terminated Unknown status Withdrawn
Clinical trials by RecruitmentTrends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
DEMOGRAPHICS: GENDERMale | Female | Both
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by GenderNumber of trials Enrolled patients
Both Female Male Blank
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by GenderBreakdown by phase (Number of Studies)
Both Female Male Blank
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by GenderBreakdown by phase (Enrollment)
Both Female Male Blank
Number of Enrolled Patients: Results skewed by several studies with very high number of subjects including three studies with unlimited number of participants (99,999,999)
Clinical trials by GenderTrends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Both Female Male Blank
STUDY RESULTSAvailability of study results for completed studiesReporting format
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by ResultsHas results No results available
Number of trials Enrolled patients
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by ResultsBreakdown by phase (Number of All Studies)
Has results No results available
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Clinical trials by ResultsBreakdown by phase (Enrollment)
Has results No results available Number of Enrolled Patients:
Results skewed by several studies with very high number of subjects including three studies with unlimited number of participants (99,999,999)
Clinical trials by ResultsTrends by Start Date & Completion Date
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Has results No results available
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
Future ConsiderationsPublished and registered trials have to be reconcilable (publication bias)
Standard format of reporting for completed trials to allow accurate assessment
Enforceable publication of results of clinical trials including negative studies
Assessment of level of evidence each trial provides
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/
ARETE-ZOE, as a consultancy, provides solutions to complex problems in the high stakes and high consequence environment of Global Pharmaceuticals, including clinical research, healthcare informatics, and public health. We blend established, Pharma sector methodologies, innovation, and adaptations/transfers from other sectors to identify and resolve consequential practices that pose risk and often result in avoidable patient casualty. However, we are specifically, not a patient advocacy group but believe in optimizing organizational effectiveness and that smart business is agile, competitive and profitable, while intrinsically safe, secure, and resilient. We work within a global context because transnational interests influence national circumstances and choices at point of prescription.
ARETE-ZOE, provides full spectrum organizational and operational risk management consultancy. Our published materials provide a glimpse of some aspects of our services to demonstrate both knowledge and ongoing participation within the Pharmaceutical Industry. Our analysis and consultancy includes all channels of misuse, diversion, counterfeiting and illicit exploitation of pharmaceuticals, medical devices, and precursor chemicals. Our advisement is to manufactures, jurisdictional entities, insurers, legislators, litigators, patients, and health care providers. This scope also frequently segues into the nexus of crime and terrorism as significant influencers that undermine sector integrity differentiated from other criminal activity. Obviously, vulnerability assessment, information collection management and intelligence production supporting decision-making for risk reduction and interventions are routinely within the scope of our services as well as design and implementation of operational control measures.
ARETE-ZOE, LLC: 1334 E Chandler Blvd 5A-19, 85048 Phoenix, AZ, USA | T:+1-480-409-0778 (24/7) | website: http://www.aretezoe.com/