Com
mittee
25 N
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Notes
Gen
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F
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S
pon
sors
24 N
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Academia-Industry Matching
Event on Superconductivity for
Accelerators for Medical
Applications
Centro de Investigaciones Energéticas Medioambientales y Tecnológicas,
CIEMAT- Madrid
Thursday 24 November 2016 – Friday 25 November 2016
Final program and
Abstracts
Website: https://indico.cern.ch/e/SC4MedAccelerators2016
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Academia-Industry matching event on superconductivity for
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Contents
Contents
1. Foreword .................................................................................................... 5
2. Committee .................................................................................................. 6
2.1 Organising Committee ................................................................................ 6
2.2 Scientific Committee ................................................................................... 6
3. General Information ................................................................................. 7
3.1 Congress Venue .......................................................................................... 7
3.2 Internet ........................................................................................................ 7
3.3 Registration desk and bags pick up ............................................................. 7
3.4 Certificate of attendance.............................................................................. 7
3.5 Coffees ........................................................................................................ 7
3.6 reception cocktail ........................................................................................ 7
3.7 Banquet dinner ............................................................................................ 8
3.8 Exhibition .................................................................................................... 8
3.9 Non-liability ................................................................................................ 8
3.10 Program Schedule ..................................................................................... 9
3.10.1 November 24, Thursday ............................................................................. 9
3.10.2 November 25, Friday................................................................................ 10
4. Introductory session ................................................................................ 11
4.1 Welcome address ...................................................................................... 11
4.2 Accelerators for medical applications ....................................................... 12
4.3 Overview of Superconductivity and its applications ................................. 13
4.4 Superconducting technology for next generation accelerators .................. 15
5. Radioisotope production session ............................................................ 17
5.1 Radiopharmaceutical production process .................................................. 17
5.2 Compact accelerators for pet production: AMIT project .......................... 19
5.3 Compact accelerators for pet production: LOTUS project ........................ 20
5.4 Compact high cyclotrons for n13 amonia and fdg .................................... 21
5.5 PET center for low patient traffic and the rf system for its cyclotron ....... 23
5.6 CERN MEDICIS and MEDICIS-PROMED: Novel radioisotope
production for medical applications ......................................................... 24
5.7 Medical imaging........................................................................................ 26
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6. Particle therapy session .......................................................................... 27
6.1 Developing a modern, high-quality proton therapy medical device using a
compact superconducting synchrocyclotron ............................................ 27
6.2 Superconducting medical accelerators at IBA .......................................... 29
6.3 Superconducting magnets for Ultra-Light and magnetically shielded,
compact cyclotrons for medical applications ........................................... 30
6.4 Modern injector linac concepts for hadrontherapy .................................... 32
6.5 Superconductivity in cyclinacs for ion beam therapy ............................... 33
7. Gantries session ....................................................................................... 34
7.1 Introduction to gantries and comparison of gantry design ........................ 34
7.2 Advantages and challenges of sc magnets in gantries ............................... 35
7.3 Superconducting magnets for medical applications at psi ......................... 36
7.4 SC gantry at nirs and new developments in sc magnets for gantries &
synchrotrons ............................................................................................. 37
7.5 Cryogenic design and colling methods for rotating sc magnets ................ 38
7.6 Cryogen free cryogenic cooling system for rotating superconducting
magnets in medical accelerators ............................................................... 39
8. Sponsors ................................................................................................... 41
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Foreword
Fo
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1. FOREWORD
In our daily life, superconducting accelerators can be used to produce short-life
radionuclides for making diagnoses, or to accelerate protons and ion beams to treat
tumours. Currently, superconductivity has become a key technology for particle
accelerators, boosting their performances and reducing their sizes.
Experienced researchers and leading companies in the field of superconductivity will
gather at CIEMAT to explore the technical challenges emerging from the design of
new particle accelerator trying to match them with state-of-the-art medical
solutions.
The scope of this workshop is to bring together experts from different fields like
superconducting magnets, cryogenics or medical physics with representatives from
industry to discuss and review the current status, the requirements and the challenges
of the technology and its applications in this field. The workshop should foster
interactions amongst people in different laboratories, institutions and industries.
The programme of the Event focuses on three main areas of expertise:
Radioisotope production
Particle therapy
Gantries
Scientific and industrial presentations, as well as Q&A sessions will be interleaved
to maximize knowledge exchange opportunities between the attendants to the event.
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Com
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Academia-Industry matching event on superconductivity for
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Committee
2. COMMITTEE
2.1 ORGANISING COMMITTEE
Susana Falcón, CIEMAT
Luis García-Tabarés Rodríguez, CIEMAT
Diego Obradors, CIEMAT
Concepción Oliver, CIEMAT
Manuela Cirilli, CERN
Jean-Marie Le Goff, CERN
Giovanni Porcellana, CERN,
Antonio de Valladares Pacheco, CERN
Anna Mccabe, ESP CENTRAL
Álvaro Bort, EEN
2.2 SCIENTIFIC COMMITTEE
Luis García-Tabarés Rodríguez, CIEMAT
Diego Obradors, CIEMAT
Concepción Oliver, CIEMAT
Jean-Marie Le Goff, CERN
Martina Bauer, GSI
Tobias Engert, GSI
Mike Seidel, PSI
Rob Edgecock, STFC
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General Information
Gen
eral Info
3. GENERAL INFORMATION
3.1 CONGRESS VENUE
The congress venue is in:
Centro de Investigaciones, Energía, Medioambiente y Tecnología, CIEMAT
Auditorium, Edificio 1
Avenida Complutense, 40
28040, Madrid, Spain
3.2 INTERNET
Wi-fi internet connection is provided in the venue. Please, note that it is a
complimentary and a basic service:
Network: Visitor
User: AIME
Password: SCMED2016
3.3 REGISTRATION DESK AND BAGS PICK UP
The registration desk is located in the main hall of the auditorium.
Opening hours:
Thursday, 24 November: 10:30 h – 16:00 h
All registrant must go to the conference registration desk in the main hall.
Each registrant will receive one copy of the final program and one
delegate bag.
3.4 CERTIFICATE OF ATTENDANCE
All certificates will be sent by email after the conference.
3.5 COFFEES
Coffees during breaks will be served in the exhibition area in the second
floor of the auditorium building. Please refer to the schedule to the
schedule for dates and times.
3.6 RECEPTION COCKTAIL
Date: Thursday, 24th from 11:30 to 13:00
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General Information
Location:Exhibition hall
Admision: All registered delegates
3.7 BANQUET DINNER
Date: Thursday, 24th at 20:30
Place: Real Café Bernabéu
Location: Estado Santiago Bernabéu, Avenida de Concha Espina, 1,
puerta 30, 28036, Madrid. +34 914583667
Admision: All registered delegates
Transportation: There will be a bus shuttle starting at 19:00 from
CIEMAT to Estadio Santiago Bernabéu.
3.8 EXHIBITION
Booths are located in the exhibition area, (second floor of the auditorium
building). Attendees are encouraged to spend time visiting booths and
interacting with the exhibitors.
3.9 NON-LIABILITY
The organisation has the right, for any reason beyond their control, to
modify or cancel, without prior notice, the sessions or any of the
arrangements, timetables, plans or other items. The organisers will not
responsible for any loss, damage, expenditure or inconvenience caused to
participants, and their belongings, either during or as a result of the
conference.
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Gen
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3.10 PROGRAM SCHEDULE
3.10.1 NOVEMBER 24, THURSDAY
11:30 - 13:00
13:00 - 13:30 Welcome Address
13:30 - 13:50 Accelerators for medical applications
13:50 - 14:10 Overview of superconductivity and its applications
14:10 - 14:30
Superconducting technologies for the next generation of
accelerators devices
14:30 - 14:50
14:50 - 15:20
15:20 - 15:40 Radiopharmaceutical production process
15:40 - 16:00 Compact accelerators for PET production: AMIT Project
16:00 - 16:20 Compact accelerators for PET production: LOTUS Project
16:20 - 16:40 Compact high field cyclotrons for N13 Amonia and FDG
16:40 - 17:10
17:10 - 17:30
PET center for low patient traffic and the RF systems for
its cyclotron
17:30 - 17:50
CERN MEDICIS and MEDICIS-PROMED: Novel radioisotope
production for medical applications
17:50 - 18:10 Medical imagining
18:10 - 18:30
Question and answer session
Radioisotope production session Chairman: Francisco Alves, ICNAS
Teresa Puig, ICMAB
Lucio Rossi, CERN
Cofee and networking break
Introductory session Chairman: Luis García-Tabarés, CIEMAT
Ramón Gavela, CIEMAT: Fernando Ballestero, MINECO
Michael Schillo, Varian Medical
Reception Cocktail
Gregory Sharkov, NIIFTA
Simon Stegemann, KU Leuven
Question and answer session
Fernado Berdascas, Beta Pharma Technologies
Javier Munilla, CIEMAT
Raymond Pommet, PMB ALCEN
Timothy Antaya, Antaya Science & Technology
Cofee and networking break
Jordi Llop, CIC BiomaGUNE
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3.10.2 NOVEMBER 25, FRIDAY
08:30 - 08:50
Developing a modern, high-quality proton medical device
using a compact superconducting synchrocyclotron
08:50 - 09:10 Superconducting medical accelerators at IBA
09:10 - 09:30
Superconducting magnets fo Ultra-Light and magnetically
shielded, compact cyclotrons for medical applications
09:30 - 10:00
10:00 - 10:20 Modern injector linac concepts for hadrontherapy
10:20 - 10:40 Superconductivity in cyclinacs for ion beam therapy Adiano Garona, TERA Foundation
10:40 - 11:00
11:00 - 11:20 Introduction to gantries and comparison of gantry design Marco Pullia, CNAO. Frank Ebskamp, Danfysik
11:20 - 11:50
11:50 - 12:10 Advantages and challenges of SC magnets in gantries
12:10 - 12:30 Superconducting magnets for medical applications at PSI
12:30 - 12:50
SC gantry at NIRS and new developments in SC magnets for
gantries & synchrotrons
12:50 - 13:10 Cryogenic design ad colling methods for rotating SC magnets
13:10 - 13:30
Cryogen free cryogenic cooling system for rotating
superconducting magnets in medical accelerators
13:30 - 13:50
Santiago Sanz, TECNALIA
Cofee and networking break break
Bertrand Baudouy, CEA Saclay
Question and answer session
Particle therapy session Chairman: Luciano Calabrett, INFN
Townsend Zwart, MEVION Medical Systems
Bernhard Schlitt, GSI
Wiel Kleeven, IBA
Joseph V. Minervini, MIT
Question and answer session
Gantry session Chairman: Jürgen Duppich, PSI
Alexander Gerbershagen, PSI
Ciro Calzolaio, PSI
Yoshiyuki Iwata, NIRS
Cofee and networking break break
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Introductory Session
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4. INTRODUCTORY SESSION
4.1 WELCOME ADDRESS
R. Gavela González
Director
Centro de Investigaciones, Energía, Medioambiente y
Tecnología, CIEMAT , Madrid, Spain
F. Ballestero Díaz
Subdirector General de Relacciones Internacionales
Secretaría de Estado de I+D+i del Ministerio de
Economía y Competitividad, Madrid, Spain
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4.2 ACCELERATORS FOR MEDICAL APPLICATIONS
Corresponding Authors: M. Schillo
Varian Medical Systems
Particle Therapy GmbH, Troisdorf, Germany
This talk will mainly focus on superconducting cyclotrons from a medical
device manufacturer's perspective. First, a short rationale of and an
introduction to particle therapy are given. The major requirements for a
particle therapy accelerator will be deduced from the treatment process.
Based on that a comparison of various accelerator types for the use in an
industrial medical device is made.
In the second part, a short history of superconducting cyclotrons up to the
current status will be presented, concluding with an outlook on future
superconducting cyclotrons.
Lecturer biography: M. Schillo
Michael Schillo is senior manager of the Advanced Development Department
at Varian Medical Systems Particle Therapy in Troisdorf, Germany.
He received his PhD in Physics at the University of Bonn for advanced beam
diagnostics for an electron storage ring. In 1992 he joined the accelerator
department at Siemens KWU, which, following a management buyout,
became ACCEL Instruments GmbH. Subsequently he worked as a technical
project manager on various development projects for superconducting
magnets and accelerator components. In 2001 he was assigned head of the
development team at ACCEL for the development of a superconducting
compact 250MeV cyclotron for the Paul Scherrer Institute, Switzerland. In
2002 with the start of the development for the Rinecker Proton Therapy
Center in Munich he took over the task to lead the development of a complete
medical proton therapy facility. After acquisition of ACCEL by Varian
Medical Systems he coordinated as engineering manager the transition of a
small business project team to a medical device manufacturer engineering
department. He is now dedicating his skills and experience to the future
advancement of Proton Therapy.
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Introductory Session
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4.3 OVERVIEW OF SUPERCONDUCTIVITY AND ITS
APPLICATIONS
Corresponding Authors: T. Puig
Consejo Superior de Investigaciones Científicas,
CSIC
Institut de Ciencia de Materials de Barcelona,
Barcelona, Spain
Superconductivity is a quantum phenomenon discovered more than 100 years
ago with important implications in our lives even though we do not usually
realise it. This exotic phenomenon is able to detect the smallest magnetic
fields and generate the largest magnetic fields in the world. In the first case,
SQUIDs (superconducting quantum interference devices) were developed as
the most sensitive magnetic field detectors and nowadays a large area of
superconducting RSFQ logics and q-bits is steady progressing in the field of
quantum computing. In the second case, high field magnets have been
extensibly developed making possible high energy accelerators and magnetic
resonance (NMR and MRI). Since the discovery of high temperature
superconductors (HTS), energy applications appeared as possible thanks to
the liquid nitrogen operation temperature. However, the nature of the HTS
materials, being ceramic instead of metallic, has strongly slowed down their
real application implementation. Thanks to one of the ever largest constant
efforts in material science during the last 20 years, nowadays these HTS
materials are industrially produced as flexible long length conductors and a
large number of different device prototypes have been demonstrated.
Recently, the scientific community has also realized that some of these HTS
materials are the highest field conductors available at helium temperatures,
thus opening new opportunities also in the area of ultrahigh magnetic fields
for high energy accelerators, magnetic resonance and fusion. In this
presentation, I will revise the most relevant properties of Superconductivity,
the superconducting materials opportunities for the different operation
temperatures and the situation of superconducting applications in the
different sectors (energy, medicine, fusion,..).
Lecturer biography: T. Puig
She received the B.S in Physics (1989) and the Ph.D. in Physics (1994) from
Universitat Autònoma de Barcelona, Spain. After pre- and postdoctoral
positions (46 months) at Royal Institute of Technology of Stockholm
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(Sweden), Trinity College Dublin (Ireland), Univesität Regensburg
(Germany) and Katholieke Universiteit Leuven (Belgium), she became
tenured scientist at Barcelona Materials Science Institute (ICMAB-CSIC) in
2000, and in 2010 she was appointed Full Professor. Since 2008 she is Head
of the Superconducting Materials and large scale nanostructures Department
of ICMAB. Her scientific interest includes functional oxides and
superconducting materials, preparation and understanding of their physical
properties, and materials integration in devices. She has been Editorial
Executive Board member of Superconducting Science and Technology (IOP-
SUST) from 2009 till 2014, and since 2005 was at the Advisory Board. She
is Board member of European Society for Applied Superconductivity (ESAS)
since 2007 and Associated Editor of the Superconducting News Forum. She
is co-founder of the spin-off company OXOLUTIA created from the ICMAB
group. She has been principle investigator of several national and EU
projects. She has published more than 275 peer review papers (with 3500
citations and h=29), holds 11 patents and has supervised 16 PhD Thesis.
She’s organized several international conferences including two MRS-spring
symposiums. She has received several awards in the area of applied
superconductivity (Duran Farrell award for Technology Research in
superconducting fault current limiters, 2002; Novare-Endesa for R+D+i in
Energy with the superconducting cable, 2007; and ITEK Award for Ink Jet
Printing for functional ceramic coatings, 2012) and this year “Barcelona City
prize to Experimental science and technology 2015”. In 2015 too, she was
awarded with an ERC- Advanced Grant in the area of superconducting
nanocomposite coated conductors using fast growth processing for ultrahigh
magnetic fields generation.
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Introductory Session
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4.4 SUPERCONDUCTING TECHNOLOGY FOR NEXT
GENERATION ACCELERATORS
Corresponding Authors: L. Rossi
European Organisation for Nuclear Research,
CERN
Technology Department, Geneva, Switzerland
Meanwhile LHC is exploring the energy frontier of particle physics, CERN
with CIEMAT and other numerous Laboratories and Institutions is
developing new technologies for next generation colliders. The High
Luminosity LHC is now near construction with Superconducting magnet
capable of 12 T field, made with advanced Nb3Sn technology, while for FCC
a new R&D phase just started to be able to reach magnetic field of 15-16
tesla. Even the 20 T range seems not impossible thanks to novel HTS based
magnets. In addition, superconducting cavities (SRF) are greatly advancing,
with more efficient and high gradient RF systems, and developing new
devices like the HiLumi Lhc crab cavities that are able to deflect or rotate
each single bunch. The talk will illustrate the advance in all these
technologies, including high current (> 100 kA) SC links, and the possible
strong impact on the future of medical accelerators.
Lecturer biography: L. Rossi
Lucio Rossi became doctor in Physics in 1980 with a thesis in Plasma
Physics; in 1992 became Professor of Experimental Physics at the University
of Milan. He worked on design and construction of the first European
Superconducting Cyclotron and then developed new superconducting
materials for accelerators (high current density Nb3Sn and high temperature
superconductors – HTS). Meanwhile he was responsible of the first LHC
dipole magnet prototype for CERN (tested in 1994, instrumental for project
approval) and of the first large Superconducting Toroidal coils of ATLS
experiment at LHC(1996-2001). In 2001 he joined CERN to lead the
construction of Magnets & Superconductors for the LHC Project, the largest
scientific instruments with a budget of more than 1.5 billion CHF. From 2010,
he is the leader of the High Luminosity LHC, an international project with a
budget of about 1 billion CHF that, through development of new cutting
technologies, aims at a five-fold increase of the luminosity of the LHC at the
horizon 2025. He is Project coordinator of the European project FP7-HiLumi
LHC (2011-2015) and the coordinator of FP7-Eucard2-WP10 (2013-2016),
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devoted to qualify novel HTS materials for future accelerators, like –but not
only - the Future Circular Collider (FCC) Project.
He has been Chair of Int. Conf. on Magnet Technology 2005 (MT-19), held
in Genova 18-23 Sept, and is member of the MT International Board since
2000. L. Rossi has received the IEEE Council of SuperConductivity Award
for sustained scientific accomplishment in applied superconductivity in 2007,
and has been nominated IEEE-CSC Distinguished Lecture for
Superconductivity for 2013-14. In 2013, he has been elevated to the grade of
IEEE Fellow. Elected member of the ESAS board (European Society for
Applies Superconductivity) for 2011-17, L. Rossi is chair of the European
Conference on Applied Superconductivity EUCAS-2017 that will be held in
Geneva.
He is very active in public outreach: he is founding member from 1985 of
“Euresis”, an association for the promotion of scientific culture established
in Milan, organizing public Science Exposition, and he gives a dozen of talks
per year to public on science and on relation between Science and
Technology, Certainty and Truth.
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Radioisotope Production Session
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5. RADIOISOTOPE PRODUCTION SESSION
5.1 RADIOPHARMACEUTICAL PRODUCTION PROCESS
Corresponding Authors: F. Berdascas Julián, C. García-Tabarés
Valdivieso
Beta Pharma Technologies, Madrid, Spain.
Radioisotope production is the first step in radiopharmaceuticals production
workflow. In an accelerator based radiopharmaceuticals production facility,
the impact of the radiopharmacy equipment on its global footprint is
sometimes as important as the accelerator itself. Accelerator design, size and
energy has a direct impact on the global installation scale: power electronics,
shielding, bunker, etc. Superconducting cyclotrons reduce considerably the
footprint of this part of the installation if compared to traditional resistive ones
allowing their installation in small hospitals or research centres. Apart from
the cyclotron it is needed to develop new targetry adapted to this new
production scale model for a cost effective radioisotope production. To
achieve a compact radiopharmaceutical production system, we need to scale
also the rest of the radiopharmacy equipment: synthesis modules, hot cells,
dose calibrators, dose dispensers and quality control equipment. Recent
developments include microfluidics based synthesis modules and compact
quality control solution. Once all this technological development will match
this new radiopharmaceuticals production model, the next challenge will be
to make it compliant with nuclear and pharmaceutical regulations which have
been created based on traditional radiopharmaceutical production
Lecturer biography: F. Berdascas
Engineering Manager and co-founder of Beta Pharma Technologies. Prior to
founding Beta Pharma Technologies in 2014, He worked as Cyclotron
Engineer for Advanced Accelerator Applications, a European leader in the
production and commercialization of molecular nuclear diagnostic
radiopharmaceuticals for PET and SPECT, and served as Chief Technical
Officer and Chief Operating Officer for Instituto Tecnológico PET, one of the
PET producer and distributor leaders in Spain.
He hold a Master’s Degree in Industrial Engineering from Universidad de
Zaragoza and a Master’s Degree in Mechanical Engineering from Université
de Technologie de Compiègne. He has attended several topic-specific
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advanced service trainings for different medical cyclotrons and has extensive
experience in PET radiopharmaceutical production
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5.2 COMPACT ACCELERATORS FOR PET PRODUCTION:
AMIT PROJECT
Corresponding Authors: J. Munilla on behalf of Unidad de Ingeniería
eléctrica, CIEMAT
Centro de Investigaciones, Energía,
Medioambiente y Tecnología, CIEMAT.
Unidad de Ingeniería Eléctrica, Madrid, Spain.
The delivery of FDG from large central production centres has demonstrated
to be a cost-effective solution for populated areas, but the interest on other
tracers has raised expectations that cannot be satisfied by using that concept.
A new production method aimed to provide in-situ single doses of 18F and,
fundamentally, 11C-radiotracers, would satisfy the requisites for non-
standard PET demands. In this context, the project AMIT has been launched
to develop, among other things, a new method for delivering single-doses of
in-situ produced radiotracers, based on a compact cyclotron.
The project proposes a compact superconducting design, based on a
Lawrence-type machine. It will be able to produce low to moderate rates of
dose-on-demand 11C and 18F. This will be achieved by accelerating 10
microamperes of H- up to 8.5 MeV. Such a simple concept of machine,
combined with a superconducting Helmholtz magnet with warm iron allows
to develop a cost-effective machine with additional features like its high
thermal efficiency (magnet can be cooled with just one commercial
cryocooler and a closed helium circuit) and a small footprint which ends on a
compact system that could be of interest to three types of potential customers:
Small remote hospitals, hospitals engaged with personalized medicine and
research institutions.
The presentation will describe the main aspects of the superconducting
technology associated to this cyclotron.
Lecturer biography: J. Munilla
Javier Munilla is at Accelerator technology group at CIEMAT since 2008. He
is a physicist and mechanical engineer who is at this moment finishing his
PhD on the magnet design of the cyclotron for AMIT project. Some of the
topics of his interest include structural and thermal modeling, high precision
mechanics and material science. In this last topic he is working as collaborator
teacher for Comillas University since 2013
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5.3 COMPACT ACCELERATORS FOR PET PRODUCTION:
LOTUS PROJECT
Corresponding Authors: R. Pommet
PMB Alcen, Peynier, France.
Molecular imaging with Positron Emission Tomography (PET) is playing an
important role in patient care, medical research, and pharmaceutical
development. But limitations in short-lived positron emitters availability
restrict the use of new radiopharmaceuticals that therefore remains limited to
a small number of advanced research facilities. In order to enlarge the use of
molecular imaging for translational research and clinical diagnosis, we
designed an automated production system for PET radiopharmaceuticals on a
“dose-on-demand” basis.
The LOTUS project is a French industry/academic partnership project, leaded
by PMB (ALCEN Group), a designer and manufacturer of particle
accelerators, RF assemblies, and advanced mechanical designs. The two other
partners involved are the CEA, a technological research public organization,
and SigmaPhi, a designer and producer of magnetic systems.
The LOTUS system features a compact 12 MeV superconducting Helium-
free magnet cyclotron, with an external self-shielded beam and targetry
system, particularly suitable for the production of Carbon-11, Fluor-18 and
Gallium-68 radioisotopes. A microfluidic GMP automated synthesis platform
allows the radiolabeling of a wide range of biomarkers for PET molecular
imaging.
Lecturer biography: R. Pommet
Raymond Pommet is senior vice president Business Development Healthcare
at PMB (ALCEN Group), responsible for developing new medical device
business initiatives and strategic partnerships.
Raymond has an extensive academic and industry experience in innovation
management and technology transfer, having spent 35 years in contributing
to bridge academic innovation and the marketplace, both in
radiopharmaceuticals and biomedical technologies.
Prior joining PMB, Raymond held different positions in product
development, marketing and business development, international cooperation
programs and innovation management, in academic institution and public
research-funding agency, as well as biomedical industry.
Raymond holds a PhD in Medical nuclear physics from the University of
Lyon and an Executive MBA from HEC Business school.
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5.4 COMPACT HIGH CYCLOTRONS FOR N13 AMONIA AND
FDG
Corresponding Authors: TA. Antaya1, K. Cameron 2
1 Antaya Science and Technology, Hampton NH,
USA 2 Ionetix Corporation, San Francisco, USA
Over the past few years Mo-99m supply instability coupled with directives to
eliminate the production dependence on HEU, have stimulated a number of
new accelerator and reactor based concepts for the production of the
important tracer Tc-99m following the conventional M0-99m carrier
route. However, if one were to start from scratch today Tc-99m would not
likely be used. There is a better cardiac imaging agent with much higher
resolution images, significantly lower doses to patients and lower dwell times
in patients, and essentially no radioactive waste- N13 Ammonia. This ‘gold
standard’ for cardiac perfusion imaging has one limiting challenge- it’s short
~10 minute half-life, which nearly requires the isotope generator, in this case
a low energy proton cyclotron and a water target, to be co-located or at least
within a half-life or two of the PET camera. In this talk we will report on the
development of a portable high field superconducting cyclotron for the
production of unit dose N13 Ammonia in near proximity to the PET cameras,
now being commercialized by Ionetix. Switching from O18 depleted water to
O18 enriched water turns this N13 ammonia generator into a unit dose FDG
generator, which will also be discussed.
Lecturer biography: TA. Antaya
Dr. Timothy A Antaya - designer, inventor, scientist, pilot, has 3 decades of
technical experience and scientific leadership in research organizations and
companies involved in the development of large scale electromagnetic
devices for basic science and related commercial applications- medicine,
security and industry. He has more than 100 research publications, and has
participated in or led 8 superconducting cyclotron campaigns, developing
more than 25 patents in the field of superconducting cyclotrons and related
technologies. His research specialties include: compact superconducting
cyclotron design, circular particle accelerator beam dynamics theory and
simulation codes, ion sources and beam formation processes, electron
cyclotron resonance ion sources, low energy beam transport, electromagnetic
field design and analysis, coupled electromagnetic mechanical design, large
scale superconductivity, cryogenics, and accelerator physics education. He is
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a member of the American Physical Society, IEEE, New York Academy of
Science, The American Association for the Advancement of Science, the
Society for Science & the Public, Scientists Without Borders, and the
American Health Council. In addition in 2014 he founded the Antaya
Foundation for Science and Technology, where annually talented high school
students can get their first real exposure in the use of basic science to make
big steps in advanced technologies
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5.5 PET CENTER FOR LOW PATIENT TRAFFIC AND THE RF
SYSTEM FOR ITS CYCLOTRON
Corresponding Authors:G.B. Sharkov, T.V. Bondarenko, A.A.
Krasonov, S. Polikhov
Institute of Technical Physics and
Automation, NIITFA, Moscow, Russia
Two topics will be discussed in the presentation. Firstly, a new high power
efficient RF generator with outstanding availability has been developed,
tested and is commercially available. The system meets the customer
demands on compactness, usability, high reliability. Special modular
architecture allowed to design scalable solution for various frequencies,
output powers and duty cycles (up to CW). Control system of the generator
has features specially designed for PET cyclotrons. The architecture and tests
of 72 MHz 10 kW CW generator prototype are presented.
A compact, modular PET center which utilizes a cyclotron with the developed
RF generator is proposed. The center is suited for regions with small
population, where one or two PET scanners are needed. The solution allows
to overcome the problem of patients, or vice versa radiopharmaceuticals,
logistics in such regions. The center consists of one or two PET-CT scanners
with the cyclotron and radiopharma production able to produce 55 GBk,
which makes the cyclotron much more compact and cheap than usual PET
cyclotrons. Also such compact cyclotron might be of interest for oncology
clinics which do not have own radiopharma production and suffer from its
logistics issues.
Lecturer biography: G.B. Sharkov
Georgy Sharkov: deputy director of project office, NIITFA (Rosatom). Ph.D.
in physics (ITEP, Moscow). Project manager of solid-state high power RF
amplifiers project (2011-2015, Siemens). Background: relativistic nuclear
physics, particle detectors.
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5.6 CERN MEDICIS AND MEDICIS-PROMED: NOVEL
RADIOISOTOPE PRODUCTION FOR MEDICAL
APPLICATIONS
Corresponding Authors: S. Stegemann
KU Leuven
Institute for Nuclear and Radiation Physics,
Heverlee, Belgium.
MEDICIS-PROMED is a network that bridges different disciplines across
fundamental research institutions, private companies and hospitals for the
production of innovative medical isotopes and radiopharmaceuticals for the
imaging and therapy of cancer. Radioisotopes are commonly used for
functional imaging and are expected to play an enhanced role in treatment of
various types of cancer.
At CERN a new facility is under construction, named MEDICIS, which will
provide dedicated medical batches for radiopharmaceuticals and develop new
accelerator technologies for medical applications. It will extend the
capabilities of the ISOLDE radioactive ion beam facility, operated with a 1.4
GeV proton beam and the on-line mass separator, which allows the
production of a spread variety of radioisotopes for different aims.
MEDICIS-PROMED is a Marie Sklodowska-Curie innovative training
network of the Horizon 2020 European Commission`s program. Outcome of
this network will be a new generation of entrepreneurial scientists, who will
take advantage of the different interdisciplinary fields, in order to develop
medical systems for new personalized medicine and to develop a network of
experts within Europe. The EU support consists of 15 PhD projects based in
different partner sites all over the Europe, which are coordinated by CERN.
MEDICIS-PROMED is a wide project that covers all aspects from the
radioisotope production to the medical application passing through the
collection, shipment, safety control and the radiochemical synthesis. The
project started in April 2015 and will end in 2019. Together with the
completion of the MEDICIS facility (2017), MEDICIS-PROMED will reach
its full speed.
Lecturer biography: S. Stegemann
Simon Segemann is a Marie-Curie Fellow from the Katholieke Universiteit
Leuven, where he is part of the Innovative Marie Sklodowska-Curie Training
Network MEDICIS-PROMED of the Horizon 2020 EU Program. He
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graduated with a master’s degree in physics from the University of Cologne
in April 2016, where he was member of the Bonn-Cologne Graduate School
of Physics and Astronomy Honors Branch (10/2013-04/2016). He is currently
living in Leuven, where he is working as a PhD student on the production of
mass separated 11C beams for PET-aided hadron therapy.
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5.7 MEDICAL IMAGING
Corresponding Authors: J. Llop Roig
CIC BiomaGUNE, Guipuzcoa, Spain.
Radiotracers labeled with positron and gamma emitters can be tracked non-
invasively after administration to a living organism. This is the basics of
nuclear imaging, which has been traditionally used in the clinical setting for
the early diagnose/evaluation of the response to treatment of a variety of
diseases. With the widespread installation of cyclotrons around the world and
the implementation of effective networks for the production and distribution
of radiotracers, nuclear imaging has gained relevance in other fields,
including the pre-clinical and clinical evaluation of new drug candidates and
the investigation of mechanistic aspects of physiological, biological and/or
medical problems.
In this session, the fundamentals of Positron Emission Tomography (PET)
and Single Photon Emission Computerized Tomography (SPECT) will be
briefly introduced. Illustrative examples of the application of nuclear imaging
both in the clinical and the pre-clinical settings will be presented and
discussed.
Lecturer biography: J. Llop Roig
Jordi Llop got his PhD degree in Chemistry in 2002. After post-doctoral
appointments in the radiochemistry laboratory at Navarra University Hospital
(Pamplona, Spain) and Uppsala University PET Centre (Uppsala, Sweden) he
became the Production Manager and Radiochemistry Laboratory Responsible
at Institut d’Alta Tecnologia (Barcelona, Spain). In October 2007, he became
Head of Radiochemistry and Principal Investigator of the Radiochemistry and
Nuclear Imaging Group at CIC biomaGUNE, which are still his current
positions.
His current research interest focuses in the investigation of nanomedicines
using multi-modal imaging, the development of novel strategies for the
preparation of 13N-labelled radiotracers and the design and evaluation of
contrast agents to assess lung ventilation using PET. Dr. Llop has published
over 75 scientific articles, he has co-edited a book, and he has trained 5 PhD
students. Currently he leads 9 researchers (6 PhD students), and he is involved
in different national and international projects related to synthesis and in vivo
investigation of novel radiotracers.
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6. PARTICLE THERAPY SESSION
6.1 DEVELOPING A MODERN, HIGH-QUALITY PROTON
THERAPY MEDICAL DEVICE USING A COMPACT
SUPERCONDUCTING SYNCHROCYCLOTRON
Corresponding Authors: T. Zwart
MEVION Medical Systems, Littleton, USA
The MEVION S250 is a proton therapy system based on a gantry mounted
superconducting synchrocyclotron. The synchrocyclotron is a 250 MeV
accelerator weighing less than fifteen tons with magnetic fields in excess of
ten Tesla and an extraction radius of only 30 cm. The compact architecture
allows delivery of high quality proton therapy without the need for beam
lines, magnetic gantries or energy selection systems. The entire system is
designed for its intended use as a medical device and is easily operable by a
single therapist without the need for additional engineers or physicists. In
addition to the superconducting magnet, the accelerator includes an efficient
frequency modulated radio frequency system with a slew rate in excess of 50
GHz/sec, maintenance free vacuum and ion source systems and a highly
stable extraction which maintains the proton energy to better than 0.1%. The
fast pulsed nature of a synchrocyclotron is also well suited for efficient and
safe pencil beam scanning delivery. The MEVION S250 Hyperscan system
has of scanning speeds of more than 10 m/sec, layer switching times of less
than 50 ms and volumetric delivery to a one liter field in six seconds resulting
in robust IMPT treatments without the need for patient specific devices.
Lecturer biography: T. Zwart
Townsend Zwart is the Senior Director of Advanced Development at
MEVION Medical Systems. Townsend joined MEVION in 2005 and was
instrumental in the design, development and deployment of the
superconducting synchrocyclotron. He holds several patents in subjects
related to the cyclotron magnet, ion source, extraction optics and beam
scanning systems. Prior to MEVION Townsend was a Research Scientist at
the MIT Bates Accelerator Center where he contributed to the development
of multiple accelerator systems including a 1 GeV electron storage ring and a
polarized electron source.
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Townsend holds a Bachelor of Arts in Physics from Dartmouth College and
a PhD from Boston University in Applied Physics with a concentration in
Accelerator Systems
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6.2 SUPERCONDUCTING MEDICAL ACCELERATORS AT
IBA
Corresponding Authors: W. Kleeven and E. Forton on behalf of
IBA1, AIMA2 and JINR3
1 Ion Beam Applications, B-1348 Louvain
la Neuve, Belgium 2 AIMA, Developpement, Nice, France 3 JINR, Dubna, Moscow Region, Russia
In 2005, IBA started studies and developments of superconducting cyclotrons
for medical applications. In this communication, we will present a summary
of the history and characteristics of the two main superconducting IBA
cyclotrons for particle therapy, namely the Cyclone 400 for proton/carbon
therapy and the S2C2 dedicated to proton therapy, with a particular emphasis
on their superconducting coil systems.
In the conclusions, we will discuss how IBA sees a trend in the use of
superconductivity in therapy equipment.
Lecturer biography: W. Kleeven
Wiel Kleeven did his PhD study at the Eindhoven University of Technology
(EUT) on the theory of accelerated orbits, including space charge issues in
cyclotrons. He then moved to Triumf for a postdoc position before returning
to EUT, where he was also appointed post-doc researcher.
Since then, Wiel Kleeven is now for more than 20 years involved in the R&D
activities of IBA. He developed in-house accelerator computing capabilities
and participated in every major design, commissioning and improvements of
medical and industrial accelerators in IBA’s portfolio.
He is now still working as senior accelerator Physicist and honorary fellow at
IBA, which allows him to also pursue collaborations and research of broader
interests.
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6.3 SUPERCONDUCTING MAGNETS FOR ULTRA-LIGHT
AND MAGNETICALLY SHIELDED, COMPACT
CYCLOTRONS FOR MEDICAL APPLICATIONS
Corresponding Authors: J.V. Minervini, A. Radovinsky, P. Michael,
L. Bromerg
Massachusetts Institute of Technology
Plasma Science and Fusion Center, Cambridge,
USA
Superconducting cyclotrons are increasingly employed for proton beam
radiotherapy treatment (PBRT). The use of superconductivity in a cyclotron
design can reduce its mass an order of magnitude, yielding significant
reduction in overall cost of the device, the accelerator vault and its
infrastructure, as well as operating costs. Despite several decades of design
effort, the magnetic configuration for superconducting cyclotrons remains
relatively unchanged from that proposed by Lawrence over 80 years ago for
resistive-magnet-based cyclotrons. The basic configuration still consists of a
single, split pair solenoid embedded in a relatively massive iron return yoke,
with the radial magnetic field profile in the acceleration region produced by a
pair of magnetically saturated iron poles. The use of a warm iron yoke also
requires the transmission of substantial electromagnetic loads across the
cryostat boundary; these loads must be accommodated in the cryogenic
design of the magnet vessel.
At MIT, we previously developed a design for a very high field
superconducting synchrocyclotron (9 T at the pole face) that results in a
compact device that is small enough and light enough to mount directly on
the beam delivery gantry, entirely eliminating the beam delivery system. As
a next step for advancing superconducting cyclotron technology we are
developing a method to design a compact superconducting synchrocyclotron
that demonstrates the possibility to reduce its weight significantly by
eliminating all iron from the design. Implementation of this proposed design
benefits from several significant advances in superconducting magnet
technology pioneered in the magnetic resonance imaging (MRI) industry
during the past 20 years, such as active magnetic shielding.
In addition to the prospect of reduced weight, smaller accelerator vault
volume, enhanced magnetic shielding, and structural efficiency, the linear
relationship between operating current and field magnitude facilitates the
development of iron-free synchrocyclotrons with the capability for beam
energy variation without a degrader. Reliance on an energy degrader comes
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at the cost of undesirable production of secondary radiation that markedly
increases the amount of radiation shielding required. Simultaneous with this
beam energy degradation is another negative consequence, reduction of the
beam current. Additionally this concept could potentially be used for
acceleration of a variety of ion species in a single device.
Lecturer biography: J. V. Minervini
Joseph Minervini is Assistant Director of the Plasma Science and Fusion
Center (PSFC) at MIT. He also is Division Head for Technology and
Engineering, and holds an academic appointment as Senior Research
Engineer in the Nuclear Science and Engineering Department where he
teaches a course and supervises graduate student research. His present duties
include spokesperson for the U.S. Magnetics Program organized under the
Office of Fusion Energy Science (OFES) in the Department of Energy.
Dr. Minervini has played a leading role in the field of large-scale applications
of superconductors for more than 30 years. He has worked on magnet systems
covering nearly every major application of large-scale superconductivity
including fusion energy, magnetic levitation, energy storage, power
generation and transmission, magnetic separation, high energy and nuclear
physics, as well as medical applications. Among his recent research interests
is the development of very high-field, highly compact cyclotron accelerators
for medical applications (proton and carbon radiotherapy, PET isotope
production), for security applications (detection of strategic nuclear
materials), and for laboratory research in nuclear physics. Another major
research focus is the application of High Temperature Superconducting
materials for advanced, compact fusion devices, and forincreasing power grid
efficiency and efficiency of data centers.
Dr. Minervini holds a B.S. Engineering degree from the U.S. Merchant
Marine Academy, Kings Point, and the S.M. and Ph.D. degrees in Mechanical
Engineering from the Massachusetts Institute of Technology.
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6.4 MODERN INJECTOR LINAC CONCEPTS FOR
HADRONTHERAPY
Corresponding Authors: B. Schlitt
Helmholtzzentrum für Schwerionenforschung,
GSI, Darmstadt, Germany
Several clinical synchrotron facilities for carbon ion-beam therapy were
constructed worldwide during the last decade. State-of-the-art at these
facilities is a compact room-temperature injector linac operated at about 200
MHz and comprising at least one electron cyclotron resonance (ECR) ion
source, a radio-frequency quadrupole linac (RFQ), and an Interdigital H-
mode drift tube linac (IH-DTL). Whereas superconducting linacs are
favorable for high-duty cycle or cw operation, room-temperature linacs still
have advantages for low-duty cycle machines like synchrotron injectors.
Recent developments applying higher frequencies and higher gradients as
well as more compact RF supplies based on solid state power amplifiers or
IOTs may open new options for future injectors. An overview of present
injector linacs as well as selected recent developments will be presented.
Lecturer biography: B. Schlitt
Since 1993 accelerator physicist at GSI Darmstadt, Germany, accelerator
operations division; currently deputy head of the Linac RF department and in
charge of the modernisation of the RF systems at the Alvarez section of the
GSI heavy-ion linac UNILAC
PhD in Physics in 1997 from Heidelberg University, Germany (Schottky mass
spectrometry at the heavy ion storage ring ESR at GSI)
1997 – 2010 development, construction, and commissioning of the 7 MeV/ u,
217 MHz carbon ion injector linacs for heavy-ion beam therapy centers
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6.5 SUPERCONDUCTIVITY IN CYCLINACS FOR ION BEAM
THERAPY
Corresponding Authors: A. Garonna, U. Amaldi, E. Felcini
TERA Foundation, Novara, Italy
Cyclinacs are accelerators, which combine the two leading technologies in
the medical field: a cyclotron injector (the workhorse accelerator in proton
therapy and radiopharmacy) and a linac booster (the accelerator type used in
every medium-sized hospital for radiotherapy and radioimaging). The linac
technology offers the unique potential to increase the performance of
accelerators for ion beam therapy, through the fast energy modulation and
small transverse size of its high repetition rate pulsed beam. This allows to
bring accelerators one step forward towards image guided ion beam therapy
and thus, to increase the quality of beam delivery for the treatment of moving
organs.
The superconducting technology plays here an essential role. Indeed, the most
cost-effective solutions for cyclinacs make use of superconducting cyclotron
injectors. Conceptual designs of such cyclotrons will be presented. In
addition, using superconducting combined-function magnets (FFAG) in the
beam delivery lines and gantries would allow to make the best use of the fast
beam energy modulation of the linac while keeping beamline (i.e. facility)
dimensions as compact as possible.
Lecturer biography: A. Garonna
Adriano Garonna obtained in 2011 his PhD from the Swiss Federal Institute
of Technology in Lausanne on the design of cyclotrons for ion beam therapy.
He subsequently designed a slow extraction system for the Bio-LEIR project
as a post-doctoral fellow at CERN and led the accelerator commissioning for
proton treatments at the MedAustron ion beam therapy centre. Adriano is
presently Technical Director at TERA, an Italian research foundation with
offices at CERN.
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7. GANTRIES SESSION
7.1 INTRODUCTION TO GANTRIES AND COMPARISON OF
GANTRY DESIGN
Corresponding Authors: M. Pullia1, F. Ebskamp2
1Centro Nazionale di Adrontetapia Oncologica,
CNAO, Pavia, Italy 2Danfysik, Taastrup, Denmark
This presentation reviews the state of the art of gantry designs and
technologies. Gantries for proton particle therapy are currently installed
worldwide, and there is a similar wish to use gantries for particle therapy
using hadrons, such as carbon and helium. Only few carbon gantries have
been built, based on normal-conducting magnets as well as superconducting
magnet technology. Several other design concepts have been proposed, such
as the Riesenrad design. A comparison of gantry designs will be presented,
including investment cost and operational aspects.
Lecturer biography: M. Pullia
Marco Pullia got his degree in physics at the Università degli Studi of Milano
(Italy) and his PhD at the UCBL in Lyon (France). He has been working in
the domain of accelerators for hadrontherapy since 1993 when he was hired
by TERA and he is with CNAO since 2003. Marco Pullia was in charge of
the accelerator during the CNAO construction is now leading the accelerator
R&D at CNAO.
Lecturer biography: F. Ebskamp
Frank Ebskamp, has a M.Sc. degree from Leiden University in the
Netherlands, and a Ph.D. degree from Danish Technical University in
Denmark. He has held several management positions in engineering
companies for the last two decades, and has been CEO for Danfysik since
2014. Danfysik provides particle accelerator technology to industry,
healthcare and research facilities.
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7.2 ADVANTAGES AND CHALLENGES OF SC MAGNETS IN
GANTRIES
Corresponding Authors: A. Gerbershagen
Paul Scherrer Institut, Villen, Switzerland.
The presentation provides an overview of the current developments in
superconducting magnets for applications in proton and ion therapy gantries.
It summarizes the benefits and challenges regarding the utilization of these
magnets from the economical, infrastructural and technical points of view.
The options for the superconducting material choice, magnet geometry,
cooling system and beam optics design are stated and their individual features
are reviewed. The challenges of fast magnet ramping and large stray fields of
the ironless magnets are presented and the possibilities to solve these
challenges are suggested. Also, the examples of currently used
superconducting particle therapy systems and proposed designs are provided.
The technical benefits and risks of these designs are discussed and the
potential new treatment and patient diagnostic options are mentioned.
Lecturer biography: A. Gerbershagen
Alexander Gerbershagen has a master’s degree in mathematical physics from
University of Cambridge and a doctorate in particle physics from the
University of Oxford, UK. He has worked at CERN on the beamline design
of a future electron-positron collider CLIC and now works at Paul Scherrer
Institute (PSI) as an accelerator physicist. His responsibilities include the
maintenance of the PSI proton therapy facility PROSCAN as well as R&D on
its upgrades. In particular, he investigates the potential use of the
superconducting magnets in future gantries.
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7.3 SUPERCONDUCTING MAGNETS FOR MEDICAL
APPLICATIONS AT PSI
Corresponding Authors: C. Calzolaio, S. Sanfilippo
Paul Scherrer Institut, Villen, Switzerland.
The use of proton therapy for cancer treatment shows a growing trend, since
the radiation dose delivered to the target volume is maximized and the dose
to the surrounding healthy tissues is minimized. To direct the proton beam
from all directions to the tumor in the patient, the last part of the beam
transport and scanning system are mounted on a rotatable gantry.
In this work a design of a superconducting bending magnet section for future
compact iso-centric gantries is presented. The section consists of three
combined function magnets: two dipole, quadrupole and sextupole magnets
and a combined quadrupole and sextupole magnet. All the winding packs are
based on racetrack coils to keep the manufacturing as easy as possible.
The coils will be wound with Nb3Sn Rutherford cables. Following the choice
of a suitable superconducting strand, we report the calculation of the AC
losses during the energy sweeps, the expected temperature margin both during
a transient and in steady state and the design of the cooling system as well as
of the mechanical support structure. Some considerations about the quench
protection scheme are also presented.
Lecturer biography: C. Calzolaio
Ciro Calzolaio studied Nuclear Engineering at the University of Bologna.
After that He got a PhD in pysics at the École polytechnique fédérale de
Lausanne (EPFL) working on the irreversible degradation in Nb3Sn Cable in
Conduit Conductors for the ITER project. After the PhD He worked at the
University of Geneva on the electromechanical characterization of Nb3Sn
strands. Since 2015 He work in the magnet group at Paul Scherrer Institute
(PSI). My main topics concern the development of superconducting magnets
for the next generation of proton therapy facilities at PSI and the upgrade of
the Swiss Light Source.
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7.4 SC GANTRY AT NIRS AND NEW DEVELOPMENTS IN
SC MAGNETS FOR GANTRIES & SYNCHROTRONS
Corresponding Authors: Y. Iwata
National Institute of Radiological Sciences, NIRS
Department of Accelerator and Medical Physics,
Chiba, Japan
A superconducting (SC) rotating-gantry for carbon radiotherapy was
developed. This isocentric rotating gantry can transport carbon ions with the
maximum energy of 430 MeV/u to an isocenter with irradiation angles of over
+-180 degrees, and is further capable of performing three-dimensional raster-
scanning irradiation. The combined-function SC magnets were employed for
the rotating gantry. The SC magnets with optimized beam optics allowed a
compact gantry design with a large scan size at the isocenter; the length and
the radius of the gantry are approximately 13 and 5.5 m, respectively, which
are comparable to those for the existing proton gantries. The total weight of
the gantry is estimated to be approximately 300 tons. Construction as well as
installation of the SC gantry was completed by the end of September, 2015.
Beam commissioning subsequently begun since October, 2015, and carbon
beams, as accelerated by the HIMAC upper synchrotron, having kinetic
energy of between 430-48 MeV/u were successfully transported with the SC
gantry to the isocenter. Presently, we are further designing a next-generation
compact SC gantry as well as a SC synchrotron as a future project. In this
talk, the recent progress of the SC rotating-gantry as well as new
developments for the future project is presented.
Lecturer biography: Y. Iwata
2000: Ph.D in Physics (Experimental nuclear physics)
~2006: Developments of a compact injector
~2011: Developments of the accelerator control system of HIMAC
accelerators for multiple-flattop operation
~Present: Developments of a superconducting rotating-gantry
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7.5 CRYOGENIC DESIGN AND COLLING METHODS FOR
ROTATING SC MAGNETS
Corresponding Authors: B. Baudouy
French Alternative Energies and Atomic Energy
Commision, CEA
Accelerators, Cryogenics and Magnetism
Division, Saclay, France
The cryogenic design of rotating superconducting magnet, especially for
particle therapy, is governed not only by the operating conditions but also by
end-user’s environment. These specific design considerations, presented as
an introduction, narrow down the different possible cryogenic cooling options
for such superconducting systems. In light of these considerations, the gantry
system design studied at CEA Saclay will be discussed and the chosen
“cryocooling” method evaluated. A focus on thermal links for cryocooling,
with a particular emphasis on the conductive thermal links, will be presented
where the pros and cons will be assessed. Based on this assessment, we
propose an alternative two-phase cryogen thermal links: the pulsating heat
pipe and discuss their thermal performance and advantages. To conclude, the
recent developments of pulsating heat pipe thermal links under development
at CEA Saclay will be presented.
Lecturer biography: B. Baudouy
Dr. Bertrand Baudouy received his PhD in fluid mechanics from the Pierre
and Marie Curie University (University of Paris VI) in Paris in 1996 for the
study on heat and mass transfer in superfluid helium in superconducting
magnets. He received his research habilitation (H.D.R.) in 2015 from the
department of physics of the University Paris-Sud (University of Paris XI).
His research activities, primarily experimental, concern the low temperature
heat and mass transfer related to the cooling techniques of superconducting
magnets or other cryo-magnetic systems. Currently, his work focuses on heat
transfer and fluid dynamics of liquid helium from superfluid to normal two-
phase regime as well as other cryogens. He is involved in the study of natural
circulation loop using different cryogens, heat and mass transfer in confined
geometry (micro-channels and porous media), numerical modeling of
superfluid helium heat transfer and the development of two-phase heat pipes
technology, like pulsating heat pipes. He is the European editor of the
Elsevier international journal Cryogenics since 2012.
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7.6 CRYOGEN FREE CRYOGENIC COOLING SYSTEM FOR
ROTATING SUPERCONDUCTING MAGNETS IN
MEDICAL ACCELERATORS
Corresponding Authors: S. Sanz, G. Sarmiento, J.M: Merino, A.
Pujana, I. Marino, L. Emaldi1, J. Sun,
R. Müller, H. Neumann2
1 TECNALIA, Derio, Spain 2 Karlsruhe Institute of Technology, KIT
Institute for Technical Physics (ITEP),
Eggenstein-Leopoldshafen, Germany
Large rotating magnets are essential components in hadron therapy facilities,
with both proton and carbon ions. In the so called gantries, the beam is rotated
and bent pointing through the patient tissues. This is achieved usually by
tilting or rotating the complete and weighty magnet system. Present trends are
directing to more compact and less power consuming gantries using
superconducting magnets, where rotating cryogenic cooling system is
required.
Under the EU Seventh Framework Programme, the SUPRAPOWER project
pursues a 10 MW superconducting generator for wind turbines. In this project,
a cryogen-free cryogenic cooling system for the generator rotor coils based
on Gifford-McMahon cryocooler has been designed and validated
experimentally. In this frame, a rotary joint has also been developed in order
to connect the rotating cold head to the stationary helium compressor. Based
on the cooling system developed for the superconducting generator, a similar
cryogen-free design is outlined for superconducting gantries. Implementation
of such rotary joints would offer a new solution for gantries with an
unbounded rotation of 360º.
Lecturer biography: S. Sanz
Santiago Sanz Castillo was born in 1977. He received his PhD degree from
the University of the Basque Country, Bilbao, Spain, in 2013, with a thesis
dedicated to the design, construction and testing of HTS coils for energy
applications. He currently works as researcher in the fields of cryogenics and
superconductivity in Tecnalia, Derio, Spain (since 2012). Before this, he has
been trained in institutions such as Ciemat and in companies such as Airbus
and Arcelor-Mittal. Over the last twelve years, he has been involved in the
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Gantries Session
development of superconducting devices, both HTS and LTS, for several
applications such as particle accelerators, wind energy and fusion.
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Sponsors S
pon
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8. SPONSORS
TESLA Engieering Ltd. is dedicated to the design,
manufacture and support of resistive and
superconducting electromagnets, gradient coils,
composite materials, generator coils, motors and
consultancy to science, medicine and industrial
markets.
TESLA Engineering Ltd. in the UK consists of
a Magnet Division and a Gradient Division which
design and manufacture magnets including bending
and focusing magnets for particle accelerators
specialized gradient coils for use in MRI systems
and advanced superconducting magnets for
emerging markets such as nuclear fusion, renewable
energy sources, semi-conductor processing and
cancer therapy.
Danfysik provides high performance particle
accelerators and related equipment for research,
health care and industry globally. Power supplies,
magnets, insertion devices,beam diagnostics,
electrostatic devices, others....
Today Danfysik has grown to be a state of the art
manufacturer of advanced technology components
and complete systems of high quality for the
synchrotron radiation and particle accelerator
markets.
Elytt Energy is an innovative company, working in
high technology projects, developing and
manufacturing equipment for particle accelerators
for scientific research and medical usage.
Elytt Energy offers complete Resistive and
superconducting eletromagnets for accelerators,
power supplies, flyweels, kinetic energy storage,
engineering...
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Sponsors
Jema IRIZAR GROUP designs and manufactures
Static Power Converters for different sectors as
Plasma physics, particle accelerators, MRI and
renewable energy.
Jema IRIZAR Group are customer orientated,
developing bespoke systems and solutions which
meet specific requirements of each project. Over 20
years, JEMA has developed several custom power
supplies for most of the experimental fusion
reactors in Europa, (MAST, JET, W7X, TJ-II, TCV,
etc...)
IBA (Ion Beam Applications S.A.) is a global
medical technology company focused on bringing
integrated and innovative solutions for the
diagnosis and treatment of cancer. IBA's proton
therapy solutions are flexible and adaptable,
allowing customers to choose from universal full-
scale proton therapy centers as well as compact
single room solutions. In addition, IBA also has a
radiation dosimetry and radio-pharmacies business
and develops particle accelerators for the
medical world and industry.
With Proteus system, developed in collaboration
with top clinical institutions, IBA is the first
company to introduce Pencil Beam Scanning, in-
room CT, Cone Beam CT or Prompt Gamma
Camera for clinical use in proton therapy.
With Cyclone systems, IBA offers packages to
manufacture radioparmaceuticals for nuclear
medicine.
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Sponsors S
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Varian medical systems have pioneered
developments in the fields of radiotherapy,
oncology, X-ray tube technology, digital image
detectors, cargo screening, and non-destructive
testing. They have a robust portfolio, and long-
standing relationships with many of the world's
leading clinicians and manufactures of industrial
and medical imaging systems.
Varian's ProBeam system is at the forefront of the
industry, having created the world´s first
commercially available system. This is able to
deliver intensity-modulated proton therapy (IMPT),
which is recognized for its effectiveness and
conformity of dose delivery.
Sedecal, Sociedad Española de Electromedicina y
Calidad S.A, was founded on January 1994 with
completely Spanish equity. During this time, they
have had a continuous growth that has positioned as
worldwide leaders in OEM design and
manufacturing of high frequency X-Ray generators
and X-Ray systems.
Sedecal has six divisions leading their field
expertise: OEM Division, medical radiology; Pre-
clinical Division, PET and PET/CT; Veterinary
Division, veterinary radiology; Healthcare
Division, medical ozone generation; Industrial
Division, industrial power control and renewable
energies; Industrial Subcontracting Division,
printed circuits boards, electronic systems and
eletromechanical systems.
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Notes
Notes
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