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Global Market for Clinical Nutrition and Dairy Ingredients 2015-2020
Published in September 2016
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Agenda
1. Introduction
3. Clinical nutrition ingredients
5. Appendix
4. Conclusions
2. Global market overview
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Market research approach- clinical nutrition markets and dairy ingredients used
Productscope
Marketscope
Keyplayers
Markettrends
Dairyingredients
in CN
• Infant• Standard• Special
• Enteral• Oral• Tube
• Parenteral
• Global• Europe• North
America• Asia-
Pacific• Latin
America• Rest of
World• Market values• Market
volumes• CAGR 2015-
2020
• Top 5players
• Brands• Products• Regional
players
• Distributionchannels
• Demographics• Regulation
• Usage ofdairyingredients
• WPC• WPI• MPC• MPI• MCC• MCI• Casein• Caseinates• Emerging
minor ingredients
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Clinical nutrition terminology
• Clinical Nutrition in this report encompasses the total market for products made available to consumers through prescriptions from healthcare professionals, i.e. doctors, medical personnel, pharmacies, or OTC that must be administered under medical supervision
• These products are designed for people with specific nutritional needs that cannot be met through a normal diet, e.g. critically ill, malnourished, and patients with metabolic disorders
The clinical nutrition market can be categorised into three primary market segments in line with industry norms:
Infant clinical nutrition: Refers to infant formula products for infants between 0-6 months of age and specially formulated products for infants with specific nutritional needs
Enteral clinical nutrition: Comprised of two subcategories oral nutritional supplements and enteral tube feedingfor people who are unable to meet their nutritional needs through an oral diet
Parenteral clinical nutrition: Refers to products delivered intravenously, straight into the blood stream when nutritional needs cannot be met through oral or enteral nutrition
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Market drivers and constraints- clinical nutrition market and dairy ingredients used
Market drivers
Population demographics
Increased incidence of diagnosed diseases
Increased awareness of nutritionbenefits in disease management
Evidence of effect
Financial perspectives
Market constraints
Regulation
Physicians knowledge of(dairy) nutrition benefits in
disease management
Consumer confidence inproducts’ health claims
Product pricing
Several market drivers and constraints for the clinical nutrition market and the use of dairy ingredients in this market can be identified and are listed below:
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Clinical nutrition market split by category- infant formula is the largest category
Infant formula (0-6 months)Market size (2015): USD xx mio
Special infant formulaMarket size (2015): USD xx mio
Parenteral nutritionMarket size (2015): USD xx mio
CAGR 2010-2015: 5%CAGR 2015-2020: 5.1%
Clinical nutrition
Total market size (2015): USD xx mio
Enteral nutrition
Market size (2015): USD xx mioCAGR 2010-2015: 7.1%CAGR 2015-2020: 5.8%
Infant formula
Market size (2015): USD xx mioCAGR 2010-2015: 9.7%CAGR 2015-2020: 6.6%
41%
10%
36%
13%
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Infant clinical nutrition- market size by region
North America
Market size (2015): USD xx mTotal volume (2015): xx MT
Europe
Total value (2015): USD xx mTotal volume (2015): xx MT
Asia-Pacific
Market size (2015): USD xx mTotal volume (2015): xx MT
Rest of the World
Market size (2015): USD xx m Total volume (2015): xx MT
Infant clinical nutrition market size and growth- segmented by regions
Total value: USD xx mTotal volume: xx MT
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Enteral nutrition market by region- North America dominated sales in 2015
31%
28%
23%
12%
6%
Regional split of global
enteral nutrition market,
2015
North America Europe Asia-Pacific
Latin America Rest of World
2010 2012 2015 2020
Enteral nutrition market size and
forecast to 2020
US
D m
io
7.1%CAGR
5.8%CAGR
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2010 2012 2015 2020
Parenteral nutrition market size and forecast to 2020
Parenteral nutrition market- Asia-Pacific region currently growing fast
US
D m
io
5%CAGR
5.1%CAGR
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Diagnostics
23%
Established
pharmaceuticals18%
Vascular
14%
Other
11%
Adult
16%
Pediatric
18%
Nutritionals
34%
Division share of sales, 2015
Abbott Laboratories Inc.- No. 1 in adult clinical nutrition
19,657
20,24720,405
18.500
19.000
19.500
20.000
20.500
21.000
2013 2014 2015
Sales
US
D m
io
• Abbott is the global leader in adult nutrition, a segment mostly consisting of clinical nutrition products and accounting for 46% of Nutritionals segment and currently expanding operations in Asia, China in particular
• Pediatric nutrition product sales accounts for 54% of Nutritionals some of which can also be characterised as infant clinical nutrition products
• Abbott is estimated to have had sales of standard milk formula of approx. USD 1.6 bn in 2015 forecast to grow with a CAGR above 7% towards 2020
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New products development- launches in the clinical nutrition market
# o
f p
ro
du
cts
lau
nch
ed
Source: Innova Market Insights
• 5174 new clinical nutrition products were launched between 2010-2016, majority of which in Western Europe followed by North America and Asia
• Out of these product launches, 2,833 contained dairy ingredients
• The most active NPL companies in this period were Nutricia (Danone) launching 1733 products followed by Nestlé with 1057 launches, trailed by Abbott with 712 launches and Fresenius-Kabi with 524 launches
376267
1418
977
682
840
614
0
200
400
600
800
1000
1200
1400
1600
2010 2011 2012 2013 2014 2015 2016
Number of new products 2010-2016- Separated by years
59
9
20
51
6
267
428
Number of new products 2015- Seprated by region
Asia Australasia East Europe
Latin America Middle East North America
Western Europe
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Danone- infant nutrition product examples
Description:Aptamil First Infant milk is a nutritionally complete formula for infants between 0-6 months as a supplement or as an alternative to breastfeeding with products coming both in liquid and powdered forms
Ingredients include: Demineralized whey powder, Vegetable Oils, Lactose, Skimmed milk powder, Galactooligosaccharides, Whey Protein Concentrate, Fructooligosaccharides, etc.
Description: Infatrini is a Food for Special Medical Purposes for use under medical supervision. Infatrini is a nutritionally complete, energy dense, RTD or tube-fed product for dietary management of infants between 0-18 months with faltering growth, or who have increased nutritional requirements and/or require fluid restriction
Ingredients include: Skimmed Milk Powder, Maltodextrin, Vegetable Oils, Lactose, Whey Protein Concentrate/Whey Protein Isolate, etc.
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Nestlé- enteral nutrition product examples
Description: Boost High Protein is a ready-to-drink product designed for people who need to increase their protein intake
Ingredients include: Water, Sugar, Milk Protein Concentrate, Corn Syrup, Vegetable Oils (Canola, High Oleic Sunflower, Corn), Cocoa, Soy Protein Isolate, Calcium Caseinate, Sodium Caseinate, etc.
Description: Peptamen is a 1.0 kcal/ml enteral tube feed formulated for optimal digestion and absorption for patients with impaired gastrointestinal function. It is a 100% whey protein based formula with 70% of the as Medium-Chain Triglycerides. Peptamen is a nutritionally complete Food for Special Medical Purposes
Ingredients include: Water, Maltodextrin, Hydrolysed Whey Protein (from milk), Medium-Chain Triglycerides, Corn Starch, Soybean Oil, Minerals, etc.
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Volume
Proteincontent
(avg. 11%)%
wheyWhey
proteinWPC share
WPC (100%protein)
WPC (80% protein)
Standard infant formula
570,000 MT 62,700 MT 60% 37,600 MT 40% 15,000 MT 18,800 MT
Special infant formula
130,000 MT 14,300 MT 50% 7,200 MT 90% 6,500 MT 8,100 MT
Total 700,000 MT 77,000 MT 44,800 MT 21,500 MT 26,900 MT
Whey proteins for infant formula- whey protein concentrate volume estimation
• Using the same methodology applied in estimating volumes of DWP used in infant formula, it has been possible to estimate the volume usage of WPC in infant formula
• Assuming that WPC accounted for the remaining 40% of whey protein content in standard infant formula, 90% in special infant formula, and adjusting for a protein content of 80%, it has been estimated that approx. 18,800 MT of WPC was used in standard infant formula, approx. 8,100 MT in special infant formula, amounting to a total demand of WPC for infant clinical nutrition of approx. 26,900 MT in 2015
• Applying the CAGR of 5% towards 2020, it can be estimated that demand for WPC in infant clinical nutrition will grow approx. 1,500 MT per year to reach approx. 34,000 MT in 2020
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Dairy ingredients in enteral nutrition- estimation of milk protein ingredient volumes
Milk protein• As per the assumptions for milk protein and adjusting for a protein content of 80%, it is estimated
that demand for milk proteins for enteral nutrition amounted to approx. 20,000 MT in 2015. It is estimated that around half of this demand is for MPC/MPI and the other half is for caseinates
• Assuming volume growth to be similar to the value CAGR of 5.8%, the enteral nutrition market has been forecasted grow, the demand for these proteins will grow approx. 1,300 MT each year towards 2020 ultimately reaching a demand of approx. 26,400 MT
Vo
lum
e (
MT)
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Emerging dairy ingredients
• Protein Hydrolysates are easily ingestible dairy proteins as they are already partially digested through the breakdown into peptides, thereby permitting better absorption in the stomach and making the protein non-allergenic. Low viscosity of these proteins makes them suitable for enteral nutrition, however bitter taste makes them more ideal for tube feeding products
• α-Lactalbumin is the primary whey protein found in human breast milk accounting for 20% of total protein and containing all essential amino acids and BCAAs needed by humans, thus making it an important protein for growth in infants. In whey from cow’s milk, β-Lactoglobulin which is not contained in human breast milk accounts for approx. 50%, and α-Lactalbumin for around 20-25%. Some premium infant formulas are produced using α-Lactalbumin for this reason
• Galactooligosaccharides are prebiotics that raises levels of certain probiotic bacteria supporting healthy gut flora and immune system function. Usage of GOS in infant formula has increased strongly in recent years. Increased use has also been seen in enteral nutrition, but at a slower rate
• Lactoferrin is a glycoprotein present in both cow and human milk with highest concentrations in the latter. It is an essential factor in immune response and particularly important to the health and functioning of the intestinal tract. In Asia, Lactoferrin is widely used in the infant formula
• Transforming Growth Factor-β2 (TGF-β2) is an exogenous polypeptide present in both human and cow milk. TGF-β2 has immune modulating functions that have been used in enteral nutrition to treat inflammatory bowel disease and Crohn’s disease
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Global Clinical Nutrition Report – project management and costs
3A Business Consulting team:
– Managing partner - Tage Affertsholt
– Junior consultant – Daniel Pedersen
Report available in PDF format – in total more than 90 slides – from September 2016
EUR 3,700
Time
Team
Cost