OPTHALMIC DYES INDOCYANINE GREEN,SODIUM FLOURESCEIN
Jahan zeb khattakPirs isra universty isra universty islamabad
CONTENTS Introduction.(dyes,iCG,flourescence
sodium) Flourescein sodium:
Action. Indication. Contraindication. Warning. Adverse reaction. Patient information. Administration and dosage.
ACTIONo Yellow water soluble dibasic acid of
xanthine series.o Demonstrate defects of corneal
epthelium.o Does not stain tissue but useful
indicater dye.o Intact corneal epithethlium resist
flourescein penetration and is not colored.Any break in the epitheliul berrier permits rapid penetration.
INDICATION topical;
Fitting contact lenses Applanation tonometry Abrasion. Ulceration. Foreign bodies detection. Seidel testInjection;examination of fundus. Evalution of the iris vasculature. Abservation of aqous flow. Differntial diagnosis of malignant and non malignant
tumors.
CONTRAINDICATION Do not use with soft contact lenses. Hyper sensitivity to flourescein or any
other component of the product. Do not use in intra ocular surgery
WARNINGS Hyper sensitivity. Pregnancy. Lactation. Children. Do not touch dropper tip toa any
surface my contaminate the solution.
ADVERSE REACTION Injection:
o Gi distress.o Cardiac distress.o Skin discoloration.o Urine discoloration.
PATIENT INFORMATION May cause strong test with use. May cause temporary yellowish
discoloration. Soft contact lenses my become stained. Do not wear contact lenses while
flourescein is being used.
ADMINISTRATION AND DOSAGE Topical:detection of foreign bodies and
corneal abrasion instill 1 or 2 drops of solution allow for few seconds.
Injection:inject the contents of the ampule or prefilled syringe rapidely into the anticubital vein after taking precautions to avoid extravasation.
Strips. Applanation tonometry strips.
INDOCYANINE GREEN A water soluble dye with a peak
spectral absption at 8100- 810nm. ICG is used to acquire an angiogram of
the choraid. ICG was first used in 1969 but was not
brought into the practical clinical setting until 1992.
INDICATION Angiography:for opthalmic angiography.
WARNINGS Pregnancy:it is not known wether indocyanine green can cause fetal harm or not. Give to pregnant woman only if clearly indicated. Lactation:it is not known wether this drug is excreted in breast milk.
\\\
DRUG INTERACTIONS Heparin preparations containing
sodium bisulfate reduce the absorption peak of absorption peak of indocyanine green in blood.
ADVERSE REACTION Anaphylactic or urticarial reaction have
also accurred an patients with history of allergy to iodides.
ADMINISTRATION AND DOSAGE Use 40 mg dye in 2 ml of aqueous
solvent.in some patient,half the volume has been found to produce angiograms of comparable resolution .
Use only the aqeuous solvent provided which specially prepared sterile water for injection
ICG is unstable in aqueous solution and must be used within 10 hours
ANY QUESTION”…???