Prevention of HIV TransmissionTreatment as Prevention or
Behavior Change Interventions?
ModeratorVictoria A Cargill, M.D., M.S.C.E.
Office of AIDS Research, NIH
Challenges Scope of the Epidemic
Global Estimate of those living with HIV2012
Challenges Awareness of HIV Status
Challenges Not Engaging in Care
The “Gardner Cascade”
Gardner E, et al. CID 2011:52 (Mar 15)
75%
50% 80% 75% 80%
79%
o
Summary
• Global pandemic• Mature epidemic• Those unaware of their HIV status account for
over half of the new transmissions• Those in care reflect only a small portion of
those living with infection
• How to interrupt the ongoing cycle of disease transmission?
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