QuickScout TM
A Comprehensive Tyrosine Kinase Profiling!
Kinase Inhibitor Profiling Service -- Comparative Inhibitory Activity
Our newest profiling services use pre-selected Tyrosine Kinase panels to permit the most rapid and thorough evaluation of potential kinase inhibitor selectivity.
77Tyrosine kinases are available NOW!
Carna Biosciences currently maintains stocks of, and has developed specific assays for 77 of the approximately 90 reported human tyrosine kinases, with more being developed continuously. QuickScout Comprehensive tests your activity modulator against each of these 77 enzymes, and offers the most complete specificity and selectivity assessment on the planet.
--- Also, we are providing custom profiling service such as IC50 determinations. Please contact us for further information! ---
For the customer on a tighter budget, our QuickScout TK Screening Panel provides similar information, but on a smaller 20-enzyme panel of typical tyrosine kinases (contact us for detailed information).
-- Available Kinases for Screening --ABLACKCSKFAK
JAK3SRCSYKTEC
EGFREphA2EphB4FGFR1
FLT3IGF1RKDRMET
PDGFRαTIE2TRKATYRO3
DDR2 TRKADDR1
CCK4
EphB1EphB2
EphB3
EphB4
EphA3EphA5
EphA4
EphA7
EphA6
EphA8
EphA2
EphA1
EphB6
EphA10
ABLARG
LCKHCK
FRK
CTKCSK
TECTXK
ITKBMXBTKALK
LTKROSINSR
IGF1R IRR FERFES
RET
FGFR2FGFR3
FGFR4FGFR1
FLT1KDR FLT4
KITFMS
PDGFRbPDGFRa
FLT3
TIE2TIE1
HER2 EGFR
HER4
HER3MET RYK
AXLTYRO3
ACK TNK1 JAK3JAK1 TYK2
JAK2
SuRTK106
ROR2ROR1
ZAP70SYKFAK
PYK2
BLKFGR
SRC YES
TRKBTRKC
SRMBRK
MER
RON
FYNLYN
MUSK
www.carnabio.com
6
7
8
ABL
ARG
ACK
TNK1 ALK
LTK
AXL
MER
TYRO
3CT
KDD
R2EG
FRHE
R2HE
R4Ep
hA1
EphA
2Ep
hA3
EphA
4Ep
hA5
EphA
6Ep
hA7
EphA
8Ep
hB1
EphB
2Ep
hB3
EphB
4FG
FR1
FGFR
2FG
FR3
FGFR
4FA
KPY
K2 FER
FES
IGF1
RIN
SR IRR
JAK1
JAK2
JAK3
TYK2 ME
TRO
NFL
T3 FMS KIT
PDGF
RαPD
GFRβ RE
TRO
SBL
KBR
KFG
RFR
KFY
NHC
KLC
KLY
NSR
CSR
MYE
SSY
KZA
P70
BMX
BTK
TEC
TXK
TIE2
TRKA
TRKB
TRKC
FLT1
FLT4 CSK
MUSK ITK KD
R
6
7
8
ABL
ARG
ACK
TNK1 ALK
LTK
AXL
MER
TYRO
3CT
KDD
R2EG
FRHE
R2HE
R4Ep
hA1
EphA
2Ep
hA3
EphA
4Ep
hA5
EphA
6Ep
hA7
6
7
8
ABL
ARG
ACK
TNK1 ALK
LTK
AXL
MER
TYRO
3CT
KDD
R2EG
FRHE
R2HE
R4Ep
hA1
EphA
2Ep
hA3
EphA
4Ep
hA5
EphA
6Ep
hA7
EphA
8Ep
hB1
EphB
2Ep
hB3
EphB
4FG
FR1
FGFR
2FG
FR3
FGFR
4FA
KPY
K2 FER
FES
IGF1
RIN
SR IRR
JAK1
JAK2
JAK3
TYK2 ME
TRO
NFL
T3 FMS KIT
PDGF
RαPD
GFRβ RE
TRO
SBL
KBR
KFG
RFR
KFY
NHC
KLC
KLY
NSR
CSR
MYE
SSY
KZA
P70
BMX
BTK
TEC
TXK
TIE2
TRKA
TRKB
TRKC
FLT1
FLT4 CSK
MUSK ITK KD
R
Staurosporine
6
7
8
ABL
ARG
ACK
TNK1 ALK
LTK
AXL
MER
TYRO
3CT
KDD
R2EG
FRHE
R2HE
R4Ep
hA1
EphA
2Ep
hA3
EphA
4Ep
hA5
EphA
6Ep
hA7
EphA
8Ep
hB1
EphB
2Ep
hB3
EphB
4FG
FR1
FGFR
2FG
FR3
FGFR
4FA
KPY
K2 FER
FES
IGF1
RIN
SR IRR
JAK1
JAK2
JAK3
TYK2 ME
TRO
NFL
T3 FMS KIT
PDGF
RαPD
GFRβ RE
TRO
SBL
KBR
KFG
RFR
KFY
NHC
KLC
KLY
NSR
CSR
MYE
SSY
KZA
P70
BMX
BTK
TEC
TXK
TIE2
TRKA
TRKB
TRKC
FLT1
FLT4 CSK
MUSK ITK KD
R
6
7
8
ABL
ARG
ACK
TNK1 ALK
LTK
AXL
MER
TYRO
3CT
KDD
R2EG
FRHE
R2HE
R4Ep
hA1
EphA
2Ep
hA3
EphA
4Ep
hA5
EphA
6Ep
hA7
6
7
8
ABL
ARG
ACK
TNK1 ALK
LTK
AXL
MER
TYRO
3CT
KDD
R2EG
FRHE
R2HE
R4Ep
hA1
EphA
2Ep
hA3
EphA
4Ep
hA5
EphA
6Ep
hA7
EphA
8Ep
hB1
EphB
2Ep
hB3
EphB
4FG
FR1
FGFR
2FG
FR3
FGFR
4FA
KPY
K2 FER
FES
IGF1
RIN
SR IRR
JAK1
JAK2
JAK3
TYK2 ME
TRO
NFL
T3 FMS KIT
PDGF
RαPD
GFRβ RE
TRO
SBL
KBR
KFG
RFR
KFY
NHC
KLC
KLY
NSR
CSR
MYE
SSY
KZA
P70
BMX
BTK
TEC
TXK
TIE2
TRKA
TRKB
TRKC
FLT1
FLT4 CSK
MUSK ITK KD
R
Gleevec
6
7
8
ABL
ARG
ACK
TNK1 ALK
LTK
AXL
MER
TYRO
3CT
KDD
R2EG
FRHE
R2HE
R4Ep
hA1
EphA
2Ep
hA3
EphA
4Ep
hA5
EphA
6Ep
hA7
EphA
8Ep
hB1
EphB
2Ep
hB3
EphB
4FG
FR1
FGFR
2FG
FR3
FGFR
4FA
KPY
K2 FER
FES
IGF1
RIN
SR IRR
JAK1
JAK2
JAK3
TYK2 ME
TRO
NFL
T3 FMS KIT
PDGF
RαPD
GFRβ RE
TRO
SBL
KBR
KFG
RFR
KFY
NHC
KLC
KLY
NSR
CSR
MYE
SSY
KZA
P70
BMX
BTK
TEC
TXK
TIE2
TRKA
TRKB
TRKC
FLT1
FLT4 CSK
MUSK ITK KD
R
6
7
8
ABL
ARG
ACK
TNK1 ALK
LTK
AXL
MER
TYRO
3CT
KDD
R2EG
FRHE
R2HE
R4Ep
hA1
EphA
2Ep
hA3
EphA
4Ep
hA5
EphA
6Ep
hA7
6
7
8
ABL
ARG
ACK
TNK1 ALK
LTK
AXL
MER
TYRO
3CT
KDD
R2EG
FRHE
R2HE
R4Ep
hA1
EphA
2Ep
hA3
EphA
4Ep
hA5
EphA
6Ep
hA7
EphA
8Ep
hB1
EphB
2Ep
hB3
EphB
4FG
FR1
FGFR
2FG
FR3
FGFR
4FA
KPY
K2 FER
FES
IGF1
RIN
SR IRR
JAK1
JAK2
JAK3
TYK2 ME
TRO
NFL
T3 FMS KIT
PDGF
RαPD
GFRβ RE
TRO
SBL
KBR
KFG
RFR
KFY
NHC
KLC
KLY
NSR
CSR
MYE
SSY
KZA
P70
BMX
BTK
TEC
TXK
TIE2
TRKA
TRKB
TRKC
FLT1
FLT4 CSK
MUSK ITK KD
R
Iressa
pIC5
0pI
C50
pIC5
0
TM
Comprehensive TK Panel ver 1.0QuickScout
TMQuickScoutTK Screen Panel ver 1.0
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