STATUS OF POTENCY REAGENTS AND CANDIDATE

VACCINE STRAINS

Food And Drug Administration

Center For Biologics Evaluation And Research

POTENCY REAGENTS

Reagents Currently Available for:

•H1N1 -A/New Caledonia/20/99

•H3N2 -A/Panama/2007/99

•B -B/Yamanashi/166/98

Candidate Strains:

•If new strains are chosen, reagents will be available in May at the earliest.

INFLUENZA A (H1N1) STRAIN

Current vaccine: Reassortant Growth•A/New Caledonia/20/99 IVR-116 Mod/high yield

Candidate strains:•No new antigenically divergent strains

INFLUENZA A (H3N2) STRAIN

Current vaccine: Reassortant Growth•A/Panama/2007/99 Resvir-17 Mod/high

Candidate strains:•A/Ulan Ude/1/2000 X-143 Mod/high

INFLUENZA B STRAINS

Current vaccine strain: Growth

•B/Yamanashi/166/98 Moderate

Candidate strains:

•B/Johannesburg/5/99 Low

•B/Victoria/504/2000 Moderate

•B/Alaska/16/2000 Low