Introduction to Epidemiology

Whether coffee and tea consumption have any causal relationship, with the incidence of

endometrial cancer

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Abstract

I have chosen McCann et al. (2009) for this assignment. In this study, the primary topic was

whether coffee and tea consumption have any causal relationship, with the incidence of

endometrial cancer. Hence, the primary explanatory variable in this case was beverage

consumption expressed in terms of consumption of normal coffee, decaffeinated coffee, and

tea. Other considered confounding variables were: age, body mass index or BMI, education

level, menopausal status, hormone replacement therapy, oral contraceptive, „ever pregnant‟,

smoking status.

The outcome for this study was the occurrence of endometrial cancer.

The study followed hospital-based observational case-control study design (chapter 5). It was

hospital-based because the data collection process happened through “part of the Patient

Epidemiologic Data System (PEDS) conducted at Roswell Park Cancer Institute (RPCI) in

Buffalo, NY, between 1982 and 1998 under an Institutional Review Board approved

protocol” (McCann et al., 2009). It was an example of observational case-control based study

because intervention was conducted on the sample; rather the sample was conducted on

patients who were admitted to the hospital as being diagnosed of endometrial cancer. Five

hundred forty one women were chosen as the controls, who don‟t have endometrial cancer.

As the sampling was scoped to a hospital in this study, so the study population was by default

limited to patients of feminine gender, who are receiving treatment or diagnosis at RCPI

against symptoms of the neoplastic disease.