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Pankaj Kusum Ramdas Khuspe M. Pharmacy (Pharmaceutics)

4.topical astringents

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Page 1: 4.topical astringents

Pankaj Kusum Ramdas KhuspeM. Pharmacy (Pharmaceutics)

Page 2: 4.topical astringents

“Brings about protein precipitation.”

E.g.: Alum

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Uses

For Styptic action

Anti inflammatory

Anti perspirant

Anti microbial

To remove unwanted skin

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Alum

KAlSO4 .12H2O

MOP:1. From Alunite or bauxite

2. By mixing conc. potassium sulphate to aluminum sulphate

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Physical Properties:

• Colorless granular crystalline powder

• Odourless

• Sweet astringent taste

• soluble in water

• Soluble in glycerin

• Insoluble in alcohol

• Aqueous solution is acidic in nature

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Uses

• Topical agent

• Astringents

• Preparation of toxoids

• Antiseptics

• Local styptic action

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Storage

“ It should be stored in well closed container at a cool

place.”

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Zinc sulphate

ZnSO4MOP:1) By heating zinc sulphate in air

ZnS + 2O2 ZnSO4

2) Mixing zinc with sulphuric acidZn + H2SO4 ZnSO4 + H2

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Physical Properties:

• Colorless powder• Odorless• Astringent taste• Very soluble in water• Very soluble in glycerin• Insoluble in alcohol• Aqueous solution is acidic in nature

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Chemical Properties

When it is strongly heated it decomposes

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Uses

• Topical agent• Astringents• Mild germicidal• Emetic• Local styptic action• Preparation of bandages and adhesive

tapes

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Storage

“ It should be stored in well closed container at a cool

place.”

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