Development and Developmental Anomalies of

the Heart

Presented by Dr. Farhana Taher Sumya

Guided by Dr. Zinnat Ara Yesmin

Objective

• Explain the development and related developmental anomalies of the heart

Establishment of the Heart Field

Establishment of the Heart Field (Primary)

Establishment of the Heart Field (Primary)

Establishment of the Heart Field (Secondary)

Establishment of the Heart Field (Side Determination)

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

FfEndothelial Tube

Fused Endothelial Tube

Bulbus CordisPrimary ConstrictionPrimitive Ventricle

Rt Dorsal Aorta

Pharynx

Truncus ArteriosusBulbus Cordis

Primitive VentricleRt Sinus Horn

Primitive Atrium

Lt Sinus Horn

Sinous Venosus

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Formation and Position of the Heart Tube

Development of the Sinus Venosus

Development of the Sinus Venosus

Development of the Sinus Venosus

Development of the Sinus Venosus

Development of the Sinus Venosus

Development of the Sinus Venosus

Development of the Sinus Venosus

Formation of the Cardiac Septa

Formation of the Cardiac Septa

Formation of the Cardiac Septa (Atrial)

Formation of the Cardiac Septa (Atrial)

Formation of the Cardiac Septa (Atrial)

Formation of the Cardiac Septa (Atrial)

Formation of the Cardiac Septa (Atrioventricular)

Formation of the Cardiac Septa (Atrioventricular)

Formation of the Cardiac Septa (Atrioventricular)

Formation of the Cardiac Septa (ventricular)

Formation of the Cardiac Septa (ventricular)

Formation of the Cardiac Septa (ventricular)

Formation of the Cardiac Septa (ventricular)

Formation of the Cardiac Septa (ventricular)

Molecular Regulation

Molecular regulation

Developmental Anomalies

Developmental Anomalies

Tetralogy of fallot

Developmental Anomalies

Atrial septal defect

Developmental Anomalies

Atrial septal defect

Developmental Anomalies

Patent ostium primum

Developmental Anomalies

Ventricular septal defect

Developmental Anomalies

Persistent AV Canal

Tricuspid atresia

Developmental Anomalies

Developmental Anomalies

Transposition ofgreat vessels

Pulmonary valve atresia

Developmental anomalies

Stenosis aortic valve Atresia of aortic valve

Developmental Anomalies

Persistent truncus arteriosus

Developmental Anomalies

Dextrocardia