Accelerating research to bring better health to more people more quickly!

CTSI Training ProgramsCTSI Training ProgramsDeborah Grady Deborah Grady

and a Cast of Thousandsand a Cast of Thousands

BMS

PIBS

PhD Biomedical Engineering

Graduate Education in

Medical Sciences)

Master’s in Translational

Medicine

Master’s in Clinical Research

Basic Basic Health PolicyHealth PolicyT1 T1 Clinical Clinical T2 T2

T1 Epidemiology Clinical Trials IDS Health Policy

Graduate Research Training Programs at UCSF

PhD in Epidemiology and Translational Sciences

CTST AimsCTST Aims• Provide superb educationProvide superb education

– TICR Certificate and Masters - Jeff MartinTICR Certificate and Masters - Jeff Martin– PhD in Epidemiology and Translation – Bob HiattPhD in Epidemiology and Translation – Bob Hiatt

• Provide superb trainingProvide superb training– Specific to level:Specific to level:

• PuP– Kirsten Bibbins-DomingoPuP– Kirsten Bibbins-Domingo• PACCTR – Joel PalefskyPACCTR – Joel Palefsky• Resident Research Program – Doug BauerResident Research Program – Doug Bauer• Fellows Program – Alka KanayaFellows Program – Alka Kanaya• K Program – Steve Hulley, Kirsten Bibbins-DomingoK Program – Steve Hulley, Kirsten Bibbins-Domingo

– Specific to area of interest:Specific to area of interest:• Graduate Education in Medical Sciences – Lou ReichardtGraduate Education in Medical Sciences – Lou Reichardt• Masters in Translational Medicine – Tejal Desai/Terry JohnsonMasters in Translational Medicine – Tejal Desai/Terry Johnson

TICR: Success by the NumbersTICR: Success by the Numbers

New Tracks in TICRNew Tracks in TICR

• Implementation & Dissemination Sciences Implementation & Dissemination Sciences and Health Policyand Health Policy– Overview and 5 additional coursesOverview and 5 additional courses

– Training program = PIDSTraining program = PIDS

• Early translational sciencesEarly translational sciences– Masters or PhD plus 2-4 courses in TICRMasters or PhD plus 2-4 courses in TICR

– Training programs = MTM, GEMSTraining programs = MTM, GEMS

Training Programs:Training Programs:Success by the NumbersSuccess by the Numbers

Pre-health Undergraduate ProgramPre-health Undergraduate Program

• UCB undergrads, aim to attend clinical UCB undergrads, aim to attend clinical prof school, interested in C&T researchprof school, interested in C&T research– Paired with PACCTR ScholarPaired with PACCTR Scholar

– Complete Designing Clinical Research plusComplete Designing Clinical Research plus• Research ethicsResearch ethics

• Literature review and assessmentLiterature review and assessment

• Measures of associationMeasures of association

– Assist PACCTR Scholar to develop protocol Assist PACCTR Scholar to develop protocol and carry out research planand carry out research plan

PACCTRPACCTR

• Students from all 4 Professional Schools Students from all 4 Professional Schools interested in C+T Research, co-funded by DDCFinterested in C+T Research, co-funded by DDCF

– Training period from 3 months to 2 yearsTraining period from 3 months to 2 years

– Students take courses in TICR, regular WIPsStudents take courses in TICR, regular WIPs

– Mentoring and counselingMentoring and counseling

– Annual research symposiumAnnual research symposium

– Core of the UCSF Pathway in C+T ResearchCore of the UCSF Pathway in C+T Research

Resident Research ProgramResident Research Program

• Residents - all Schools and disciplinesResidents - all Schools and disciplines– New 4-week course (DCR for Students and New 4-week course (DCR for Students and

Residents) completed by 60 residents this year Residents) completed by 60 residents this year with close to 100% completing a protocolwith close to 100% completing a protocol

– Resident Research Scholar Program (1-year)Resident Research Scholar Program (1-year)

– Provides mentoring and counselingProvides mentoring and counseling

– Small grant program for research and travel to Small grant program for research and travel to present research findingspresent research findings

– Annual Resident Research SymposiumAnnual Resident Research Symposium

Fellows ProgramFellows Program

• Fellows who complete ATCR or MastersFellows who complete ATCR or Masters– Works-in-progress focused on preparing Career Works-in-progress focused on preparing Career

Development (K) proposalDevelopment (K) proposal

– Coordinated with TICR course on “Writing a K Coordinated with TICR course on “Writing a K Grant”Grant”

– Of 8 fellows this year, 5 submitted K grants, 3 Of 8 fellows this year, 5 submitted K grants, 3 fundedfunded

• Support T32 preparation and renewalSupport T32 preparation and renewal

K ProgramK Program

• Marked expansion to individual K grantsMarked expansion to individual K grants– Over half of the K Program ScholarsOver half of the K Program Scholars

– Supports WIPs, expert advice, collaborationSupports WIPs, expert advice, collaboration

• $75,000 salary plus $25,000 research support$75,000 salary plus $25,000 research support• Masters in Clinical Research or equivalentMasters in Clinical Research or equivalent

• Mentoring and career adviceMentoring and career advice

• Expertise and training in design, biostatistics, Expertise and training in design, biostatistics, writing, practical aspects of study conductwriting, practical aspects of study conduct

Masters in Translational MedicineMasters in Translational Medicine

• Jointly sponsored by UCB and UCSFJointly sponsored by UCB and UCSF– Students who wish to apply engineering and Students who wish to apply engineering and

business approaches to improve healthbusiness approaches to improve health

• Interdisciplinary trainingInterdisciplinary training• Core courses in research methods, engineering, Core courses in research methods, engineering,

device development, regulatory issues, businessdevice development, regulatory issues, business

• Team projects and interdisciplinary mentoringTeam projects and interdisciplinary mentoring

• Practical experience/capstone project in solving Practical experience/capstone project in solving real problems in translational engineeringreal problems in translational engineering

Graduate Education in Medical ScienceGraduate Education in Medical Science

• Graduate students and Post-docs: co-Graduate students and Post-docs: co-funded by HHMI and CTSIfunded by HHMI and CTSI

• Phased involvementPhased involvement• All students - website, 6 mini-courses, qtrly seminar, All students - website, 6 mini-courses, qtrly seminar,

2 new courses: Immunity and Immunopathology and 2 new courses: Immunity and Immunopathology and Introduction to Human Biology and MedicineIntroduction to Human Biology and Medicine

• Certificate – 4 courses in TICR; training in a specific Certificate – 4 courses in TICR; training in a specific clinical discipline; co-mentored by basic and clinical clinical discipline; co-mentored by basic and clinical researchersresearchers

• Stipends/Masters – develop protocol for and Stipends/Masters – develop protocol for and complete a translational research studycomplete a translational research study

Program in Implementation and Program in Implementation and Dissemination Science/Health PolicyDissemination Science/Health Policy

• Faculty, fellows, trainees interested in Faculty, fellows, trainees interested in implementation and health policyimplementation and health policy• Curriculum – 6 courses taken individually or as a Curriculum – 6 courses taken individually or as a

track in TICRtrack in TICR

• Supports, funds and mentors UCSF trainees from all Supports, funds and mentors UCSF trainees from all 4 schools at all levels4 schools at all levels

• Supplemental Program -training in implementation Supplemental Program -training in implementation research for community-base health providersresearch for community-base health providers

• Community-based Organization Internship – 6 month Community-based Organization Internship – 6 month field placement in community health organizationsfield placement in community health organizations

CTST Major PlansCTST Major Plans

• Expand early translational education Expand early translational education and trainingand training

• Develop online courses/programsDevelop online courses/programs

• Improve diversityImprove diversity

• Improve program evaluation metricsImprove program evaluation metrics

• Pursue independencePursue independence