By: Jesse Winker

Ovall Mann

Courtney Pringle

Conn’s syndrome(hyperaldostronism)

www.mcghealth.org/.../adrenal_tumor.jpg

Conn’s syndrome is an Adosterone-Producing Adenoma.

Conn’s syndrome named after American endocrinologist Jerome W. Conn.

Condition was first described at the University of Michigan in 1955

History

Where Is It Located?

urologyhealth.org

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Conn’s Syndrome is a disease that effects the adrenal glands.

It involves excess production of a hormone called aldosterone. (which is the hormone that regulates sodium and potassium reabsorption by the cells of the tubular portion of the kidney.)

What does It Effect?

Essential hypertension can mimic Conn's syndrome.

Conn’s syndrome can also be lead to the buffalo hump (Cushing syndrome)

Therefore high blood pressure and low blood potassium may be due to essential hypertension, which is being treated with diuretic drugs that cause a loss of potassium in the urine.

WHAT ELSE COULD IT BE?

Conn’s syndrome normally effect most people in their 30-60 years of age.

Conn’s syndrome is normally found in female cases then male.

Conn syndrome occurs in 50-60% of cases of primary hyperaldosteronism.

Who does It effect?

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Frequent urination (polyuria)

Increased thirst Weakness and fatigue HeadacheMuscle crampsTingling in fingers Temporary paralysisHeart palpitationsHypertension (high blood

pressure)

Symptoms

adrenalstressblog.wordpress.com/

Diagnose

The appearance of the tumor on CAT scans

You can identify it on a MRI

diagnosticimaging.com

www.med-ed.virginia.edu/.../anatomy/adrenal.html

The goal of treatment is to lower blood pressure.(any other symptom)

If tumor appears on gland then the gland will be removed.(laparoscopic surgery)

All symptoms associated with Conn’s syndrome are resolved and further treatment involves controlling blood pressure .

Treatment

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Most adrenal disease requiring surgery can be done using minimally invasive (laparoscopy) surgery techniques. Laparoscopic adrenalectomy is the preferred technique for non-cancerous adrenal disease, including the following:

Aldosterone-secreting adrenal tumors (Conn's syndrome)Cortisol-secreting adrenal tumors (Cushing's syndrome)Adrenalin-producing adrenal tumors (Pheochromocytoma)Primary adrenal hyperplasiaAdrenal hyperplasia after failed treatment of Cushing's

diseaseLarge nonfunctioning adrenal tumors (<10-12cm)Adrenal metastasis

When does it call for surgery?

performed under a complete general anesthesia. A cannula (a narrow tube-like instrument) is

placed into the abdominal cavity in the upper abdomen or flank just below the ribs.

A laparoscope (a tiny telescope) connected to a special camera is inserted through the cannula. This gives the surgeon a magnified view of the patient's internal organs on a television screen.

Other cannulas are inserted which allow your surgeon to delicately separate the adrenal gland from its attachments. Once the adrenal gland has been dissected free, it is placed in a small bag and is then removed through one of the incisions. It is almost always necessary to remove the entire adrenal gland in order to safely remove the tumor.

After the surgeon removes the adrenal gland, the small incisions are closed.

Surgery

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After surgery patient usually cared for by a surgical nursing unit.

Usually enlisted into intensive care to monitor he patient blood pressure.

Patients with an aldosterone-producing tumor will need to have their serum potassium level checked after surgery

Patients cortisol-producing tumors need to take prednisone or cortisol

Recovery

woldfitness.com

http://normalpotassiumlevels.com/measuring-blood-potassium-levels

http://www.sages.org/publication/id/PI14/http://

surgery.wustl.edu/Surgery_M.aspx?id=976&menu_id=178

http://www.instablogsimages.com/1/2011/09/02/pills_and_pills_kwia3.jpg

http://emedicine.medscape.com/article/117280-overview

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Cites