8. Hypothyroidism: Hypothyroidism is a common endocrine
disorder resulting from deficiency of thyroid hormone.
9. Risk Factors woman older than age 60 Have an autoimmune
disease Have a close relative autoimmune disease Have been treated
with radioactive iodine or anti- thyroid medications Received
radiation to your neck or upper chest Have had thyroid surgery
(partial thyroidectomy) Have been pregnant or delivered a baby
within the past six months
10. SKIN Cool and pale Sweating is decreased Yellowish tinge
Hyperpigmentation Coarse hair Hairloss Non pitting edema Cold
intolerance Dry skin
13. Respiratory Fatigue Shortness of breath on exertion
Hypoventilation Sleep apnea Hoarseness of voice
14. Gastrointestinal Constipation Ascites Weight gain Gastric
atrophy
15. Reproductive Oligorrhea Amenorrhea Menorrhagia Decreased
fertility Early abortion
16. Neurologic Mental slowing Myxedema coma Mental
retardation
17. Myxedema coma The condition occurs in patients with
long-standing, untreated hypothyroidism. mental status, including
lethargy stupor delirium(acute confusional state) coma
20. Normal values TSH 0.4- 5.0 mU/L Total T4 4.6-11.2 mcg/dl
Total T3 75-195 ng/dl Free T4 0.8-1.8 ng/dl Free T3 2.3-4.2
pg/ml
21. Treatment INITIAL DOSE Young healthy-1.6mcg/Kg wt
Elderly-50mcg TIMING OF DOSE Half an hour before food SIDE
EFFECTS-Rare Allergy to dye in the tablets
22. MONITORING Every 6 weeks If TSH is not with in normal range
increase the dose by 12.5-25mcg If TSH normal ,monitor TSH once a
year
