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PHARMACOLOGICAL MANAGEMENTBLOOD GLUCOSE-LOWERING MEDICINES
Objectives
Aims of treatment
UKPDS: long-term glucose control
Natural history of type 2 diabetes
Mechanism of action
Biguanides
Biguanides
Sulphonylureas & Meglitinides
Sulphonylureas
Thiazolidinediones
Alpha-glucosidase inhibitors
GLP-1 (Incretin Mimetic Agent)
DPP- 4 inhibitors
Action of GLP-1 & DPP-4 inhibitors
Understanding the names
Activity
The principles of combination therapy
Expected effect of glucose-lowering medicines
Adherence rates
Strategies to help people remember
Activity
Blood glucose targets
Suggested starting medicine (1 of 2)
Suggested starting medicine (2 of 2)
Increasing or adding
Older people with diabetes
Older people with diabetes
Activity
Case study
Summary
References