Compensatory Enlargement of Human Atherosclerotic Coronary Arteries

N Engl J Med 1987 May 28;316(22):1371-5

<50% stenosis

Luminal area is not endangered until more than 40% of internal elastic lamina is destructed and occupied by plaque

Coronary artery disease is a disease of arterial wall disease not lumen.

Positive Remodeling<80%

stenosis