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Dr Dayanath Mishra MD, DM, DNB (NEPHRO) Chairman, DM Hospitals Pvt Ltd, Thakurpukur, kolkata Prescription Error – Can it be prevented ?

Prescription Error - Can it be prevented?

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Dr Dayanath MishraMD, DM, DNB (NEPHRO)

Chairman, DM Hospitals Pvt Ltd, Thakurpukur, kolkata

Prescription Error – Can it be prevented ?

Medicines can do a lot of good but they also have the potential to cause harm

•Nuclear power

•European railroads

•Scheduled airlines

Less than one death per 100 000 encounters

•Driving•Chemical

manufacturingOne death in less

than 100 000 but more than 1000

encounters

•Bungee jumping

•Mountain climbing

•Health care

More than one death per 1000

encounters

How dangerous is health care?

A prescription ( ) is a health-care program ℞implemented by a physician or other qualified practitioner in the form of instructions that govern the plan of care for an individual patient

Medical Prescription

Prescriptions can help people stay healthy or manage long-term conditions or emergency situations. However, as with other components of healthcare, prescriptions are also subject to error and can lead to unintended harm. Medication errors are one of the most common patient safety issues and prescribing errors are one of the most common types of medication errors.

Medical Prescription

Of a medical practitioner :-

advise and authorize the use of (a medicine or treatment) for someone, especially in writing

Medical Prescription

LEGAL DOCUMENTATION

RECORD SOURCE

MEANS OF COMMUNICATION

THERAPY MODALITY

MEANS OF MEDICAL CONTROL OF THERAPY

MEANS OF CLINICAL TRIAL

Manifest functions of the prescription

There is no global standard for prescriptions and every country has its own regulations.

The most important REQUIREMENT is that the prescription be clear. It should be legible and indicate precisely what should be given

Information on a prescription

Always remember

“to Err is Human!”

Commonly encountered in health care settings. They can lead to inefficient delivery of health care thus jeopardizing patient

care.

Prescription Errors

Failure in the treatment process that leads to, or has the potential to lead to, harm to the patient.

Medication Error

“A clinically meaningful prescribing error occurs when, as a result of a prescribing decision or prescription writing process, there is an unintentional significant

Reduction in the probability of treatment being timely and effective or

Increase in the risk of harm when compared with generally accepted practice”.

The definition

• 1. Unnecessary drug • 2 Incorrect drug • 3 Duplication • 4 Allergy error • 5 Contraindication error • 6 Interaction error • 7 Dose/strength error • 8 Formulation error • 9 Frequency error • 10 Timing error • 11 Information incomplete • 12 Generic/brand name error • 13 Omission error relating to

failure to prescribe concomitant treatment

• 14 Inadequate documentation in medical records

• 15 Quantity error • 16 Inadequate review• 17 Duration error

Medication Error

A monitoring error occurs when a prescribed medicine is not monitored in the way which would be considered acceptable in routine general practice. It includes the absence of tests being carried out at the frequency listed in the criteria,

Monitoring Error

Monitoring not requested

Requested but not done

Results not available

Results not acted upon

Monitoring Error

Medication errors are one of the most common causes of patient harm and prescribing accounts for

a large proportion of medication errors

Medication Error

Conservatively, at least 1.5 million people per year are harmed by medications.

Many medication mistakes are never reported.

100,000 people die each year as a result of medication errors.

Medication Error Statistics

Prescribing errors

3-20 per 1000 prescriptions

Medication errors

1 per patient per day

Been estimated that drug errors account for 1/5 of all deaths due to

adverse drug events

Reported Incidences

Difficult to estimate due to varying definitions - US/UK

The study involved examination of 6,048 unique prescription items for 1,777 patients

Prescribing or monitoring errors were detected for one in eight patients

Investigating the prevalence and causes of prescribing errorsin general practice (The PRACTICE Study)

The authors found that 39% of 256 residents had one or more prescribing errors, with 8.3% of prescriptions (or intended prescriptions) affected. The most common types of prescribing error were “incomplete information” (37.9%), e.g. no strength or route was specified; ‘‘unnecessary drug’’ (23.5%), ‘‘dose/strength error’’ (14.4%) and ‘‘omission’’ (11.8%).

The PRACTICE Study

Male gender, age less than 15 years or greater than 64 years, number of unique medication items prescribed,

Prescribing or monitoring errors were not associated with the grade of GP or whether prescriptions were issued as acute or repeat items.

A wide range of underlying causes of error were identified relating to the prescriber,

The PRACTICE Study

Prescribing

Transcribing

Dispensing

Administering

38%

12% 11%

Medication Errors Reporting Program US

Major Areas for Medication Error

39%

doctors are under a legal duty of care to write clearly,

that is with sufficient legibility to allow for mistakes

by others.

When illegible handwriting results in a breach of that

duty, causing personal injury, then the courts will be prepared to punish the

careless by awarding sufficient damages.

Liability does not end when the prescription leaves the doctor's consulting room.

It may also be a cause of the negligence of others.

Legal obligation to write clearly

Reducing Prescribing Errors

Training personnel to better prepare them for tasks and work conditions is a human factors approach

Education and development

Redesigning equipment and tasks can reduce prescribing errors

Tools

One-to-one education- Prescription error rates decreased from 41% to 24% at the hospital receiving academic detailing and the confidence of junior doctors in writing prescriptions increased.

Group education for trainees

Group education for qualified professionals

Education and development

Most studies suggest computerised tools can reduce prescribing errors

Emerging evidence suggests that to be successful, human factors such as workflow features, tool design and context need to be considered

Computerised Tools

Computerised physician order entry (CPOE)

This is an electronic process for entering instructions about patient treatment

reduce errors related to handwriting or transcription,

E-prescribing

Forcing functions & constraints

Automation & computerization

Standardization & protocol

Checklist & double check system

Rules & policies

Education/ Information

Be more careful, be vigilant

Mosteffective

Leasteffective

Steps to Minimize Medication Error

Use pharmacy system that will not fill any order unless allergy information, patient weight & height are entered

Use computer order entry with dosage checks

Remove dangerous IV drugs (e.g. conc. potassium, hypertonic sodium chloride) from ward stock

Limit choices of available drugs in pharmacy

Limit dosage strengths & concentration for each drug

Mix IVs in the pharmacy

Steps to Minimize Medication Error

Forcing functions & constraints

"The central government has approved to amend Indian Medical Council Regulations, 2002, providing therein that every physician should prescribe drugs with generic names in legible and capital latter and he/she shall ensure that there is a rational prescription and use of drugs"

-JUN 12, 2015

Now doctors have to write prescription in capital letters

Dr. K K Aggarwal of Indian Medical ASSOCIATION (IMA) said this will help decrease prescription errors and it is a cheaper alternative to electronic health records.

"Prescription errors will decrease. It will become uniform. One drug has 10 odd brands. The patients will be now able to know whether the drug is generic or not," Aggarwal told PTI.

"In US alone, 100,000 prescription errors occur every year. India does not have any data on this. This is a cheaper alternative to electronic health records. It will take some time for doctors to get used to it," he said.

JUN 12, 2015

Now doctors have to write prescription in capital letters

Use drug-drug interaction checking system

Use computerized order entry

Use computerized patient information

Use bar-coding on drugs, containers, medication records, patient wristbands

Automated dispensing on patient care unit

Steps to Minimize Medication Error

Automation & computerization (Reduce reliance on memory)

No error –prone abbreviations

Use generic names rather then brand name

Use standard equipment—one kind of pump or syringe

Use protocol for complex medication administration e.g. heparin, chemotherapy

Steps to Minimize Medication Error

Standardization & protocol

Over a period of time, there has been a transition from an era where medical practice and its practitioners were revered to a

time when doubt and fear is expressed and legal suits are pursued by aggrieved patients.

The Changing Scenario

What do I need to prescribe in a safe way?

Patient information

Co-morbid conditions

Drug information

Pharmacology

Pharmacokinetics and pharmacodynamics

Therapeutics

Systems

Policies, guidelines, prescribing aids etc

Think About

ALWAYS write legibly.

ALWAYS space out words and numbers to avoid confusion.

ALWAYS complete medication orders.

AVOID abbreviations.

When in doubt, ask to verify.

Maximize Patient Safety

THE RIGHT PATIENT

THE RIGHT DRUG

THE RIGHT TIME

THE RIGHT DOSE

THE RIGHT ROUTE

Remember the “Five Rights”

Thank you

Prescription Error – It can be prevented…

Acknowledgement :

Technology team DR DMTECH Pvt. Ltd.Staff DM Hospitals Pvt. Ltd.Dr. Reddy’s Lab, Nephrology DivisionAll my patients…