Action Potential Simulation
APS TherapyFor pain relief, energy enhancement & injury
repair
MS Therapy Centre, Bedford
Where I work
APS Therapy machines
My story with APSMS NurseBackground in holistic health, diet,
nutrition, seekingPWMS have a lot of painNeuropathic &
nociceptiveMedications like anti-epileptics = fatigue, weight
gainMore activity = more painLead to cycle of deconditioning &
disability
My story with APS
Hull film
Patient experiences
As well as MS I also Suffer with Anklosing Spondylitis which
gives me quite a lot of back pain. The MS itself was making me feel
exceptionally tired & I was struggling with bad head aches
& a recurring sinus issue. A treatment plan was put together
for me & within 2 weeks of starting the treatment I was no
longer waking up every morning with bad headaches. My energy levels
were greatly improved & my backache was reduced.I would
definitely recommend this treatment to other people. I have now
purchased my own unit so that I can use it at home. I addition to
the treatment plan I have also used the APS machine to combat
menstrual pain very effectively. In summary using this machine in
addition to leading a healthy lifestyle has helped me to stay
active & continue to enjoy an active lifestyle.
How I got into pain !
In her own wordsnotes on progress of 4th week.Sleep improvements
maintained although still wake frequently.Pain during day virtually
gone.Pain at night much reduced now only troubling between
6-8am.Energy levels greatly improved. Much more stamina was able to
withstand this hot spell very well.I can now easily get up from a
chair even one without arms!And get up from the toilet.
I can lower myself gently down instead of flinging myself down.I
can move around with ease and no longer have to plan everything I
need to do. I can walk around the centre without a stick.I can
stand long enough to do some housework and get myself some
lunch.The electric shock feelings I was experiencing in the head
have been getting less in frequency.The physio that I do in the
group and in the pool have got better.I can stay on a gym ball for
the whole session and the physio has noticed as improvement in my
posture and walking.Mood- has elevated to new heights. I am
delighted with the transformation I feel I am gettingme back.
Maggie Harvey. MS for over 20 years.
2 hats
AimTo help people relieve their painTo train healthcare
practitioners Raise awarenessTo stimulate researchFor APS Therapy
to take its place as a validated treatment for pain relief,
available on the NHS.
2016 testimonialsI have better mobility, less fatigue and the MS
hug has diminished. Am I completely cured of the MS symptoms? No,
but I have a quality of life I have not known for a number of
years. I was dreading retirement, thanks to APS at the Centre I am
not just embracing my retirement but actively looking forward to
it, with active being the operative word! I dont have to use a
stick to walk, how wonderful, liberating and normal, not huge I
know, butfeels so much more normal to carry a handbag than a stick!
Jacqueline, Reading MS Therapy Centre, 2016
What is APS TherapyAPS Therapy machineAction Potential
Simulation Safe, effective, drug free pain relief & injury
repairSpecific wave form microcurrent electricity
HistoryDeveloped in early 1990s, south AfricaFirst machine
treated shattered elbows successfullyProf Christian Barnard used
for arthritis to keep working1993 1st serial machine MD in USA1994
FDA approval1998 CE approval ( Europe)1998 Gold award Geneva
Medical International InventionMarketed without training in SA
& UKMoved to Holland, model of training &
therapistsInsurance, hospital clinics
How does it work?Specific waveform simulates Action
Potentials
Real Action Potential
Action potentials
Action potentials
A series of biochemical reactions take place, lasting just
thousandths of a secondElectrically charged molecules of sodium or
potassium rush in and out of cells, as gates in the cell membranes
open and closeWhen they get to certain concentrations, they trigger
a electrical impulse, a firing and a depolarisation,sending a wave
of information along to the next cell, and setting up for the next
wave of action potential.
Action PotentialsThe change in electrical potential associated
with the passage of an impulse along the membrane of a muscle cell
or nerve cell
occur in nerve cells, muscles cells and endocrine cells
nerve impulses or as the cell firing.
Action Potentials
Boosting action potentials1) Communication between cells is
enhanced = ++ removal of waste products, reduced inflammation2)
Boosts production of ATP = speeds cellular repair and regeneration
3) Neuro-hormonal effects= contribute to pain relief and maximised
healing 4) Effect on voltage gated sodium channels & pathways=
may be why effective with long term neuropathic pain on
maintenance.
Benefits to userPain reliefBetter quality of sleepEnhanced
energyFaster injury repairImproved recovery time after exerciseAlso
reported:Improved mobilityReduced spasms in MSCessation of
recurrent UTIsReduction in medication useImproved wellbeing
2016 testimonialsBy the end of the first week, my walking was
better noticed by others who know my usual unsteady gait. My hip
pain was reduced, meaning I didnt need to take the daily tramadol
as much, missing it completely on most days. I am sure it has
improved the quality of my sleep. The MAJOR, MAJOR benefit is with
my fatigue.I have had fatigue pretty much all of the time, to
differing levels, for some time. With a lot of family health
problems this year it been worse than ever.BUT the fatigue levels
have been dropping and I am aware I have more energy.I am able to
focus more (I can now concentrate to read and enjoy a book).I am
able to do more around the house and am more alert and staying out
later when socialising. The APS has been quite transformational for
my fatigue - Ros, Reading MS Therapy Centre 2016
1) Assists cellular communicationAssists removal of waste
products
Decongests area from products of inflammation
Reducing inflammation
Sports injury before, during, 5, & 10 minutes post APS
Therapy
2. ATP & neuro-hormone productionstorage and distribution
vehicles of energy
adenosine, ribose, and three molecules of phosphate.Energy is
released when the phosphate bond is broken.Function: convert
glucose, from food, into energy.more ATP = better function and more
energy
Electron Transport Chain
By simulating the electron transport chain, production of ATP is
boosted28
Neuro-hormonal effects
Melatonin: significantly raised sedative, anxiolytic,local
vasodilation & anticoagulation, limitation of tissue damage at
sites of inflammation due to the effects on prostaglandins and free
oxygen radicals.Leukine enkephalin: progressively
increasedEffective analgesic due to interaction with opioid
receptors as well as inhibition of substance P (the
neurotransmitter responsible for pain transmission). Limitation of
tissue damage at sites of inflammation and/or hypoxia. Increase in
pulse rate and systemic blood pressure, associated with
peripheralvasodilation, which results in better perfusion at the
affected areas. -
29
Neuro-hormonalBeta-endorphins: significantly decreasedFeelgood
hormone produced at times of stress.
Cortisol: unchanged but uninhibitedstress hormone harmful when
chronic over production, necessary in short term for performance,
esp. high level. Inhibited in the presence of beta-endorphins.
Neurohormonal Consequences of APS TherapyProf. Dr. J.M.C.
Oosthuizen MBCHB; DMEDSCI University of the Free State;Prof. Dr.
E.H. de Wet MBCHB; MMED; MD
3. Pain Pathways
Simulation of extra action potentials may work to calm
disordered excitatory nerve signalling via activation of voltage
gated ion channels.
Improvement in sleepGrowth hormones, cellular repair secreted
stages 3 & 4
Sleep in fibromyalgia
simulation vs stimulation
TENSAlternating currentForeign pulseGate theory pain
reliefEndorphin on tapping modeAPS TherapyDirect currentBiological
frequenciesStimulating ATP, detox, injury repair Benefits accrue
and are more lasting No accommodation
34
Jackie
Jackie after 4 weeksBefore I started the treatment I had the MS
hug really badly. Most of the time the pain score was 5/10, but at
times it was 11/ 10! Since I started the APS Therapy I havent had
the really bad pain at all and most of the time the pain score is
around 3.5/10, too low to notice. I also had knee pain, which was
about 4.5/10 on the pain scale, and 7/10 when bad. Again, since
having this treatment I havent had the bad pain at all and the pain
score has gone down to around 3/10. The fact that I no longer
notice pain shows the improvement. Its just so nice not to have to
constantly think about pain.This treatment has also had a real
impact on my sleep and fatigue. I usually wake up four or five
times a night with pain, but last week I only woke once. Also, I
dont have that overwhelming feeling of tiredness. Last week I did
so much! I took my brother on holiday, which involved so much
walking. Normally, I would have been exhausted, but I just wasnt.
My numbness is less noticeable too.Jackie Clarke, Luton
ResearchA 2015 randomised controlled trial comparing APS Therapy
with Interferential ( another micro-current therapy) found
significant reductions in both VAS and WOMAC ( arthritic symptoms)
in both groups using only 10 treatments; Timed Up and Go was also
reduced in the APS Therapy group.(8)-Eftekharasadat, B,
Babaei-Ghazani, A., Habibzadeh,A.,Kolahi,B.(2015) Efficacy of
action potential simulation and interferential therapy in the
rehabilitation of patients with knee osteoarthritis.Therapeutic
Advances in MusculoSkeletal disease 7(3): 6775.
A study in 1999 on APS Therapy compared with TENS in 99 patients
with osteoarthritis of the knee did not find a significant
difference given just 6 treatments over a 2 week period. Noted that
the APS group showed a significant improvement in measures of knee
flexion and swelling, which persisted even 1 month after the last
treatment. - Odendaal & Joubert APS Therapy- a new way of
treating chronic backache, a pilot studySouth African Journal of
Anaesthesiology and Analgesia.1999;51
Research in APSAn assessment of APS Therapy on 285 Patients with
Chronic Pain in 2002 reported a mean average VAPS was 6.8 before
treatment and 3.3 after treatment in the over 50s, and 6.3 and 2.2
respectively in the under 50s. Out of the 285 patients,44 (15%)
ended with a 0 VAPS and 199 (69%) with a score of 5 or
less.-Papendorp DH van. (2002). Assessment of Pain Relief on 285
patients with chronic pain. Biomedical Research2002;26:249-253.
A trial of APS Therapy in patients awaiting or having
neurosurgery for intractable spinal pain concluded that the number
of patients treated was too low to reach a statistical conclusion,
but that the trend was very promising and they recommended that
patients waiting for destructive surgery should first be put on a
thorough trial of APS Therapy.(2)- Du Preez, J. Neurosurgical Pain
Conditions, University of Pretoria
ResearchIn a 1999 randomized, patient blinded,
placebo-controlled study, on 76 patients with chronic osteoporotic
back pain, reported pretreatment baseline VAPS value average of of
57.79, and post- treatment value after the sixth treatment of 9.7
(p= 0,0001); 6 patients maintained benefits 6 months post
treatment.(3)-Berger, P. Matzner, L Study on 99 patients with
osteoarthritis (OA) of the knee to investigate the effectiveness of
low frequency electrical currents on mobility and pain: Action
Potential Simulation therapy (APS) current compared with
transcutaneous electrical nerve stimulation (TENS) and
placebo.South Africa Journal of Anaesthesiology and Analgesia
Action Potential Simulation Therapy ( APS Therapy) for
neuropathic and nociceptive pain in people with MS
Shhhh!Up to date findings from our 2nd and 3rd year of data
cannot be shared online at the current time as we are presenting at
conferences internationally and bound by exclusivity
agreements..
But we can share our first years experiences:
Findings: 201342 people began the course 6 dropped out1 x
Migraine1 x Vomiting1 x Discouragement after 2 weeks1 x Visual
disturbance2 x Ill with pre-existing medical condition
Of 38 people who completed an 8 week course of APS Therapy:
Of 61 pains that the 38 people had:
Of the 50 pains that improved;
Improvement
Counted as 1 whole point on the VAS
Average improvement overall was 4.7 points
12 people reduced or discontinued medication
Could have been more, hadnt planned
14 Neuropathic pain in feet & legsAverage VAS pre: 6.3
Average post: 2.5
Worst pain in neuropathic feet & legs
Other neurogenic & nerve pain
Joint pain & injury
Pre mean 5.1 post mean 2.2. Actual results quite polarised
Average pain scores for joint pain or injury had a pre treatment
mean of 5.1 and fell 2.9 pointson the VAS to a mean of 2.2 . Actual
results were quite polarised, with 4 people having noresponse, and
7 going to pain free.50
worst pain for joint pain/injury
Headaches
The remaining pains were: 2 x muscle fatigue type pain no result
1 x post pin and plate no result
1 x psoriasis pain good result1 x varicose vein pain good
result
Other benefits attributed include:
Increase in energy, reduction in fatigue x 4Reduction in swollen
legs & ankles x 2Alleviation of life-long insomnia x 2Cessation
of recurrent UTIs x 2Improvement in circulation &
discolourationReduction of fatty lump on hipDisappearance of
swollen glands on neckCessation of fluid on skull
sensationReduction in dizziness & improved cognitive
function
Questions?
Thankyou & contacts
Miranda Olding RGN MSCN MCMA
www.painfreepotential.co.uk www.mirandasmsblog.com01908
799870
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