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Statistics 2 Simon Carley

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  • 1. Statistics 2 Simon Carley

2. Objectives Understand RR ARR and NNT. Learn how to convert one to the other. Understand why natural frequencies are so much more helpful to physicians. 3. RR ARR NNT Whats the difference between Relative Risk Absolute risk reduction Number needed to treat 4. Work something out 10% of AMI patients are dead at one month. A new treatment reduces the mortality to 5% Work out the RR, ARR and NNT 5. Work something out 10% of AMI patients are dead at one month. A new treatment reduces the mortality to 5% Work out the RR, ARR and NNT RR - 5/10 = 50% reduction ARR - 10-5 = 5% reduction NNT - ARR/100 = 20 patients treated to achieve one positive result. 6. Work something out again 20% of AMI patients are dead at one month. A new treatment reduces the mortality to 10% Work out the RR, ARR and NNT 7. Work something out again 20% of AMI patients are dead at one month.A new treatment reduces the mortality to 10% Work out the RR, ARR and NNT RR - 10/20 = 0.5 = 50% reduction ARR - 20-10 - 10% reduction NNT - 10/100 = 10 patients to achieve one positive result 8. RR, ARR, NNTHow much better is it to do an internal jugular line with ultrasound as compared to an internal jugular line with landmark method? 9. NNH Number needed to harm Same as NNT but the other way round 10. More complex stuff Regression Recursive partitioning Survival analysis Odds ratios 11. Summary RR ARR and NNT are the same thing. NNT helps us understand RR often clouds our understanding