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Superb Microvascular Imaging Applications Dr. Muhammad Bin Zulfiqar PGR IV New Radiology Department SIMS/SHL

Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

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Page 1: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

Superb Microvascular ImagingApplications

Dr. Muhammad Bin ZulfiqarPGR IV New Radiology Department SIMS/SHL

Page 2: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

Superb Microvascular Imaging

• Superb microvascular imaging is the latest in the technological advances in the field of sonography and offers clear visualization of the microvasculature without the need of contrast.

• In conjuction with contrast its efficacy flourished further.

Sara O hara, www.medical.toshiba.com

Page 3: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

Modes Of SMI

• SMI operates in two modes.• Monochrome SMI (mSMI) which subtracts the

background image from the detailed vasculature.

• Color SMI (cSMI) which displays the flow components in color overlaid on the grayscale B mode image.

Dr. Jiro Hata, Seeing the Unseen New Techniques in Vascular Imaging. ©Toshiba Medical Systems Corporation 2014.

Page 4: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• We see that low flow velocities are lost in conventional color doppler due to clutter and other artifacts, while in SMI even low flow vasculature can be imaged.

Dr. Jiro Hata, Seeing the Unseen New Techniques in Vascular Imaging. ©Toshiba Medical Systems Corporation 2014.

Page 5: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• This Diagrammatic illustrations clearly shows that power, color and Advance doppler flow (ADF) have limitations regarding velocity range and resolution while SMI have no limitations and not influenced by motion artefacts.

Dr. Jiro Hata, Seeing the Unseen New Techniques in Vascular Imaging. ©Toshiba Medical Systems Corporation 2014.

Page 6: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

Normal Appearance of Vasculature

• Sparse flow can be detected.• Fine details of vasculature can be elicited.

Page 7: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Normal Vasculature of Placenta. (a). Conventional doppler (b,d,e). SMI techniques (c,f) pulsed doppler combined with SMI.

Page 8: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

Comparison of color doppler (right) and cSMI (left) from the liver of a young patient. cSMI shows greater detail and better visualization of small branching vessels.

Sara O hara, www.medical.toshiba.com

Page 9: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Comparison of gray scale (right) and cSMI (left) from the kidney of a young patient. cSMI shows greater detail and better visualization of small branching vessels up to the cortex at a high frame rate of 50 fps.

Sara O hara, www.medical.toshiba.com

Page 10: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

Modes Of SMI• Comparison of color

doppler ( top right), cSMI (top left), gray scale (bottom right) and mSMI (bottom left) from the kidney of a young patient. cSMI and mSMI shows greater detail and better visualization of small branching vessels up to the cortex.

Sara O hara, www.medical.toshiba.com

Page 11: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Comparison of gray scale (right) and cSMI (left) from the kidney of a 17 years young patient. cSMI shows greater detail and better visualization of small branching vessels up to the cortex at a high frame rate of 50 fps.

Sara O hara, www.medical.toshiba.com

Page 12: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Gray Scale (right), mSMI (mid) and pulse Doppler (left) images of testis in a young patient with scrotal pain demonstrates good vasculature

Sara O hara, Toshiba superb microvascular imaging A new problem solving tooll in pediatric radiology www.medical.toshiba.com

Page 13: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Conventional color Doppler poorly visualizes vasculature in a normal pancreas, SMI shows even fine vascular structure.

Page 14: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• In normal liver, we can see a tiny vessels just beneath the surface of the liver.

Page 15: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• cSMI (bottom) depicts more blood flow and better vessel detail than color doppler (top) in this suspicious lump in the neck. SMI provides stronger evidence than Color Doppler to not drain the suspected abscess.

Sara O hara, Toshiba superb microvascular imaging A new problem solving tooll in pediatric radiology www.medical.toshiba.com

Page 16: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

Clinical Applications• Characterization of Reactive and Malignant Lymphadenopathy.• Characterization of blood flow in Malignancies.

– HCC, Gastric cancer, GIST, Bladder tumors, malignant melanoma, squamous cell carcinoma, Lymphoma.

• Characterization of Inflammatory Lesions– MSK (Rheumatoid Arthritis) – IBD (Crohn’s Disease, Ulcerative Colitis)

• Characterization of Placental Lesions• Others

– Placental Insufficiency– Testicular Torsion– Laceration of spleen and– Non occlusive mesenteric Ischemia etc.

Page 17: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Placental Ischemia. SMI images show that the placental flow is sparse to absent. Baby delivered at 28 wks of gestation due to preeclampsia. Histological examination revealed extensive area of marginal infarction.

Dr. Pascale bach segura. Supurb microvasculature imaging in the analysis of fetoplacental microvascular blood flow. Toshiba medical system corporation 2015.

Page 18: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Heterogeneous lesion of the subchorionic placenta close to the umblical cord insertion into the placenta.

• On color doppler only largest arteries are seen.• SMI shows microvasculature within the lesion, confirm the diagnosis

and evaluates hemodynamic decompensation by detecting microvascular areas and necrotic areas.Dr. Pascale bach segura. Supurb microvasculature imaging in the analysis of fetoplacental microvascular blood flow.

Toshiba medical system corporation 2015.

Page 19: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• The grayscale image (top right) shows a suspicious lesion near the surface of the liver. With conventional ADF (top left) at a velocity range of 9 cm/s some vessels can be recognized but the pattern of the tumor vessels cannot be determined. When we lower the velocity range to 3 cm/s (bottom right), the image is badly distorted by the clutter. Once we activate mSMI (bottom left), we can see the internal tumor vessels whose basket shape strongly indicates HCC

Dr. Jiro Hata, Seeing the Unseen New Techniques in Vascular Imaging. ©Toshiba Medical Systems Corporation 2014.

Page 20: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Liver metastasis originating from a jejunal gastrointestinal stromal tumor (GIST)

Dr. Jiro Hata, Seeing the Unseen New Techniques in Vascular Imaging. ©Toshiba Medical Systems Corporation 2014.

Page 21: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Bladder carcinoma

Dr. Jiro Hata, Seeing the Unseen New Techniques in Vascular Imaging. ©Toshiba Medical Systems Corporation 2014.

Page 22: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Gastric cancer

Dr. Jiro Hata, Seeing the Unseen New Techniques in Vascular Imaging. ©Toshiba Medical Systems Corporation 2014.

Page 23: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Cervical lymph nodes (malignant lymphoma)

Page 24: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Malignant melanoma • Squamous cell carcinoma

Page 25: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Gastrointestinal stromal tumor of the ileum

Page 26: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Rheumatoid arthritis (radio-carpal joint)

Page 27: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Subcutaneous abscess due to Crohn’s disease

Page 28: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Necrotizing lymphadenopathy

Page 29: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Laceration of the spleen

Page 30: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• Even on cSMI no blood flow is seen in left testis depicting Testicular torsion.

Page 31: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• NOMI (non-occlusive mesenteric ischemia

Page 32: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

• mSMI detection of the urinary reflux in the renal pelvis (red arrow) in a peadiatric patient who is on treatment for UTI

Page 33: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

Advantages• Provide exquisite vascular details quickly.• Save time.• Improve Diagnostic confidence compared with conventional

sonographic techniques.• SMI can rapidly confirm the presence or absence of blood flow in

cases of torsion and ischemia.• No need of Intravenous Contrast.• It offers

– Better detail resolution– Faster frame rates– Less clutter– Fewer flash artefacts

Page 34: Superb microvascular imaging A Sonographic Technical AdvanceDr. Muhammad Bin Zulfiqar Services Institute of Medical Sciences / Services Hospital Lahore

Take Home Message

• AS it has become cleared that SMI is far superior to conventional sonographic techniques so every sonographic imaging should be added with SMI