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Benha University Hospital, Egypt Aboubakr Elnashar

TVT: Long term results

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TVT: Long term results

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Page 1: TVT: Long term results

Benha University Hospital, Egypt Aboubakr Elnashar

Page 2: TVT: Long term results

•By placing a prolene tape around the

midurethera without tension Restores

the pubourethral ligaments & the

suburetheral vaginal wall Dynamic

kinking of the midurthera at stress (Rezapour et al, 2001)

•Corrects the central & lateral fascial

defects of the anterior compartment of the

vagina (Ursula et al,2000) Aboubakr Elnashar

Page 3: TVT: Long term results

1.Anticoagulant therapy (stop 14 d or

replace with low dose heparin)

2.Urinary tract infection

3.No sexual intercourse, heavy

lifting or exercise for 1mo

Aboubakr Elnashar

Page 4: TVT: Long term results

1.Genuine SI.

2.SI with Intrinsic sphincter deficiency (urethral p <20 cm H2O).

3.Mixed I (urge & stress).

4.Recurrent SI (previous traditional

surgical procedure had failed).

Aboubakr Elnashar

Page 5: TVT: Long term results

1. Pregnancy

2. Women with plan for future pregnancy (prolene

mesh will not stretch significantly).

Incontinence may recur.

3. Motor urge incontinence & significant detrusor

instability (Ulmsten,2001)

Aboubakr Elnashar

Page 6: TVT: Long term results

• Ursula et al,2000: 8.7% in 1762 patients

1. Bladder perforation: 5.4%. The most frequent

complication

2. De novo urgency or urge incontinence: 5.1%

3. Retropubic haematoma: 0.8%

4. Rare complications

a. Anterior vaginal wall laceration

b. Retained plastic sheath

c. Obturator nerve irritation

d. Vaginal wound infection Aboubakr Elnashar

Page 7: TVT: Long term results

• Cochrane library, 2002: 682 women

•1 in 11 had a complication during TVT,

•Most commonly bladder perforation

•None had serious consequences

Aboubakr Elnashar

Page 8: TVT: Long term results

Ursula et al(2000) 1762 patients

Objective improvement: (Cough stress

test, pad test, urodynamics)

87.3%

Subjective improvement:

89.3%

Aboubakr Elnashar

Page 9: TVT: Long term results

4 different groups of patients:

GSI, Recurrent, ISD, Mixed

Cure: Pad test < 10 g of urine/24 h,

Quality of life improved > 90%

Improvement:Pad test <15 g of urine/24 h,

Quality of life improvement >75%

Aboubakr Elnashar

Page 10: TVT: Long term results

1.Genuine SI

Nilsson et al, 2001:85 patients, follow-up 5 yrs

• Retropubic hematoma: 3.3%

Bladder perforation: 1.1%

Intraoperative bleeding >200ml: 3.3%

Postoperative voiding difficulties: 4.4%

UTI: 7.8%

Infection of operating site: 1.1%

Aboubakr Elnashar

Page 11: TVT: Long term results

•Complete cure (no leak at all & no voiding problems): 84.6%

Significant improvement (leak occasionally): 10.6%

No significant decline in efficacy over an extended period

Failure rate: 4.8%

• De novo urge symptoms: 5.9%

Aboubakr Elnashar

Page 12: TVT: Long term results

2.Recurrent SI

Rezapour & Ulmsten, 2000: 34 patients, Follow up for 5

yrs

• No significant intra-or postoperative complications

Bladder perforation: 1 patient

Post operative urinary retention: higher than that of

uncomplicated SI

• Cure rate: 82%

Significant improvement: 9%

Failure: 9%

• No long term complications

Aboubakr Elnashar

Page 13: TVT: Long term results

3.SI with ISD (hypotonic urethera, Type 3

incontinence)

Difficult to cure

Rezapour et al,2001: 49 women, follow-up 4 yrs

• Bladder perforation: 1 patient

Small hematoma: 11%

Temporary postoperative voiding problems: 23%

Aboubakr Elnashar

Page 14: TVT: Long term results

• Complete cure: 74% (equal or better

than traditional surgery)

Significant improvement: 12%

Failure: 14% (more than that in genuine

SI). The majority in >70 yrs, urethral p

<10 cm H2O & immobile urethra.

• No LT complications, No LT urinary

retention

Aboubakr Elnashar

Page 15: TVT: Long term results

4.Mixed ( urge & stress)

Rezapour & Ulmsten, 2001: 80 women, follow-up 4 yrs

Urge component may consist of:

1.detrusor instability with low bladder volume <200 ml (excluded & treated with anticholinergics),

2.uretheral relaxation or

3.uninhibited premature micturition reflex

• Postoperative voiding problems: 18%

Bladder perforation: 1 patient

Small heamatoma: 8% & Significant haematoma: 1patient (on anticoagulant)

Aboubakr Elnashar

Page 16: TVT: Long term results

• Cure rate: 85%

Improvement: 4%

Failure: 11%

Urgency without incontinence: 25% of the cured & improved women

Aboubakr Elnashar

Page 17: TVT: Long term results

Provided that a urodynamic evaluation is done, TVT can be used in mixed I.

Not only the stress but also the urge I was cured or improved in 85%. ?

TVT:

1. Minimal vaginal dissection, the tape is placed tension-free around the mid urethra. So, the proximal part of the urethra & bladder neck which are densely innervated would be less compromised than in other sling operations

2.Causes only dynamic Kinking of the midurethera at stress & less likely to obstruct urine flow at micturition

Aboubakr Elnashar

Page 18: TVT: Long term results

•Cochrane library, 2002: 682 women

•Cure rates after TVT were similar to those

following open abdominal retropubic

suspension.

•No difference in: voiding dysfunction,

urge incontinence or

detrusor instability between

suburetheral slings & abdominal or needle suspensions Aboubakr Elnashar

Page 19: TVT: Long term results

•Ursula et al,2000

Contrary to Burch colposuspension in which a

continuous decline of success, no such

deterioration has been reported with TVT

TVT creates a new hammock under the

midurethera. The tape is invaded by fibroblast

during the course of time, thereby stabilizing its

position with time

Aboubakr Elnashar

Page 20: TVT: Long term results

1. TVT cannot be expected to treat all types of

incontinence

2. TVT is effective, safe & long lasting, also in

previous operated patients

3. TVT can be used in ISD SUI, even with low

cure rate compared to GSI

Aboubakr Elnashar

Page 21: TVT: Long term results

4. TVT can be used in MSI to cure or

improve also urge symptoms

5. TVT results are comparable to traditional

surgery but simple & less invasive

6. TVT cure rate is about 90% lasting for 5

yrs, with few intra & postoperative

complications

Aboubakr Elnashar

Page 22: TVT: Long term results

E-mail: [email protected]

Aboubakr Elnashar