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Zoonotic Influenza Zoonosis Pandemic Epidemic Definition Sharmaine Villamor 1

Zoonotic Influenza

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Sharmaine Villamor1

Definitions:Zoonosis: disease of animals transmissible to humans under natural conditionsInfluenza: an acute viral infection of the respiratory tract, occurring in isolated cases, epidemics, and pandemics, caused by Influenzavirus A, B or C (AKA The Flu)Pandemic: A widespread epidemic of a disease Epidemic: Occurring suddenly in numbers clearly in excess of normal.

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Zoonotic Influenza Pictures

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How does this virus work?

RNA Virus (smaller than a cell)

Has no cell wall

Invades other cells

Alters the infected cell and its DNA

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Influenza A is made of 8 parts, called segments

Those 8 segments are used to make 10 larger components called gene productsThese determine certain aspects of the virus Include products called Hemagglutinin and Neuraminidase, or HA and NA for short.Commonly recognized in the name of the strain of the virus, such as H1N1

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Control how this virus interacts with the host cell

HA: How well the virus gets along with the host cell1Friend or foe: Do I know you?Come on in, make yourself at home

NA: How well the children of the virus can detach from the inside of the host cell to spread to other cellsAllows the children to leave the nestChildren move in with someone else, start their own families

Why we classify the strain by the H and N variations.

HA and NA?Sharmaine Villamor6

Hey, look, its a party! (The door is openwith the right HA key)Mix with your friendsDecide to stay (Hey, why not, the food is free, and the party never stops?)Start talking to the other DNA segmentsSpread some urban myths

How about a little Antigenic Drift?Have children, (slow random genetic changes)Kick the kids out when theyre old enough (replication)

What happens next?Sharmaine Villamor7

RabiesLyme DiseaseMosquito-borne DiseaseAnimals in Public SettingsFood-borne DiseaseAvian Influenza

Sharmaine Villamor8Common Zoonotic Disease Question Areas

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