45
Testing for Central Auditory Processing Disorders Harvey Dillon With thanks to: Sharon Cameron Helen Glyde Wayne Wilson Pia Gyldenkaerne Mridula Sharma Dani Tomlin 1

Testing Central Processing Disorders

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Page 1: Testing Central Processing Disorders

Testing for Central Auditory Processing Disorders

Harvey Dillon

With thanks to:

Sharon Cameron

Helen Glyde

Wayne Wilson

Pia Gyldenkaerne

Mridula Sharma

Dani Tomlin

1

Page 2: Testing Central Processing Disorders

On the basis of evidence, what should CAPD testing and

remediation services consist of?

What gaps in evidence are there that our research should fill in

the future?

Suggestions to Pia and Dani in the interpretation of their data

2

Page 3: Testing Central Processing Disorders

A clinician’s question

• Does this child have a problem hearing or understanding sound that adversely affects him or her, and that I or anyone else can do something about? • What is the specific nature of the problem? • Is there a specific remediation for that problem? • Are there general management techniques that might

minimize its effects?

3

Page 4: Testing Central Processing Disorders

Impact of criterion on diagnosis of CAPD

0 50 100

Fail ≥2 tests [ASHA (2005), AAA (2010)]

Fail ≥1 tests [ASHA (2005), AAA (2010)]

Fail ≥1 non-speech [McArthur, 2009]

Fail ≥1 speech + ≥1 non-speech [BSA(2011)]

Reported sympotoms [Ferguson (2011)]

Percent of children “with CAPD”

Binaural fail Monaural fail

Wayne Wilson 4

Page 5: Testing Central Processing Disorders

What is a fail on one test?

40 60 80 100 120 140 160

-4 -2 0 2 4Z-score

Prop

ortio

n of

chi

ldre

n

Test score

5

Page 6: Testing Central Processing Disorders

Test score sensitivity relative to functional listening ability

• Can estimate from correlation between test scores and functional ability – Questionnaire scores of listening ability – Educational attainment scores

0

50

100

150

-3 -2 -1 0 1 2 3

Func

tiona

l lis

teni

ng a

bilit

y

CAPD test z-score 6

Page 7: Testing Central Processing Disorders

Test score sensitivity relative to functional ability:

• Sensitivity = ∆ 𝐹𝐹𝐹𝐹𝐹𝐹𝐹𝐹𝐹𝐹 𝑧−𝑠𝐹𝐹𝑠𝑠∆ 𝐶𝐶𝐶𝐶 𝑧−𝑠𝐹𝐹𝑠𝑠

7

Page 8: Testing Central Processing Disorders

Criteria for adopting a CAPD test

• Test is associated with variation in functional ability – High sensitivity (= ∆ 𝐹𝐹𝐹𝐹𝐹𝐹𝐹𝐹𝐹𝐹 𝑧−𝑠𝐹𝐹𝑠𝑠

∆ 𝐶𝐶𝐶𝐶 𝑧−𝑠𝐹𝐹𝑠𝑠)

– Deviant results common in clinical population – Attributes tested minimally shared with other tests in battery

• Test result indicates specific remediation necessary (and remediation affects real life)

• Time taken is small • Test is minimally affected by attention, intelligence,

motivation, working memory • Associated with a known anatomical site and neural

mechanism

8

Page 9: Testing Central Processing Disorders

First a brief background on the LiSN-S

9

Page 10: Testing Central Processing Disorders

Same Voice - 0° Condition Different Voices - 0° Condition

Same Voice - ±90° Condition Different Voices - ±90° Condition

Spatial Advantage

Talker Advantage

(LiSN-S) Conditions

Low cue

High cue

Sharon Cameron 10

Page 11: Testing Central Processing Disorders

Results profile: spatial processing disorder

11

Page 12: Testing Central Processing Disorders

Target: The horse kicked six wet shoes LiSN & Learn training software

Cameron & Dillon, JAAA, 2011 12

Page 13: Testing Central Processing Disorders

Effect of training on LiSN-S scores

Low cueHigh Cue

Talker advantageSpatial advantage

Total advantage

LiSN-S scale

-3.0

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

LiSN

-S score (popn S

D

Pre

Post

Follow-up

Cameron & Dillon, JAAA, 2011 13

Page 14: Testing Central Processing Disorders

LiSN & Learn - Performance Over Time (n=9) Li

SN

& L

earn

SR

T (d

B)

10 dB

Bet

ter

Cameron & Dillon, JAAA, 2011 14

Page 15: Testing Central Processing Disorders

Randomized Control Trial Earobics Lisn & Learn

N = 5 N = 5

Group: LiSN & Learn

Low CueHigh Cue

Talker AdvSpatial Adv

Total Adv-6

-5

-4

-3

-2

-1

0

1

2

3

LiSN

-S S

core (P

opulation Stand

Group: Earobics

Low CueHigh Cue

Talker AdvSpatial Adv

Total Adv

Pre-training Post-training

Cameron et al 15

Page 16: Testing Central Processing Disorders

Experiment 1 Dani Tomlin current PhD study • Two subject recruitment groups:

– Children referred to Uni of Melbourne Audiology Clinic due to suspected APD (n=65) • Teachers, parent, speech pathologist referral

– Normative group (n=47) • School enrolment, open invitation

• Age range of 7–12 years • Both groups to complete full test battery • Results converted to Z scores (derived using age

specific norms)

16

Page 17: Testing Central Processing Disorders

Measures obtained • Dichotic Digits Test (DDT): Binaural integration (Musiek, 1993) • Frequency Pattern Test (FPT): Temporal sequencing (Musiek et al, 1990) • Gaps in Noise (GIN): Temporal resolution (Musiek et al, 2005) • MLD: Binaural interaction (Bellis, 2003) • LiSN-S: Binaural integration – spatial listening ability (Cameron & Dillon, 2006)

• Memory CELF-4: Forward and reverse digits • Attention: BrainTrain®: Continuous Performance Test: Sustained auditory and

visual attention • Cognition -TONI-4: Nonverbal cognitive assessment

• Questionnaires and interview: – Child completed LIFE questionnaire & recorded interview – Parent completed Fisher checklist & written interview – Teacher Evaluation of Auditory Performance (TEAP) & written interview

• Academic Performance - NAPLAN & WARP (reading fluency)

17

Page 18: Testing Central Processing Disorders

Relations between outcome variables Matrix Plot (Dani Feb24 data.sta 113v*112c)

Listening Capability Score

Average NAPLAN Literacy Z score

WARP Z SCORE

18

Page 19: Testing Central Processing Disorders

Test score sensitivity relative to functional abilities Dichotic digits - left Dichotic digits - right Freq pattern - left Freq pattern - right

List

enin

g ca

pabi

litie

s Re

adin

g flu

ency

Dani Tomlin

Lite

racy

Average NAPLAN Literacy Z score = 0.4145+0.1672*x

-10 -8 -6 -4 -2 0 2 4RDD ASIN Z Score

-3

-2

-1

0

1

2

Average

Average NAPLAN Literacy Z score = 0.6834+0.2485*x

-10 -8 -6 -4 -2 0 2 4LDD ASIN Z Score

-3

-2

-1

0

1

2

Average

Average NAPLAN Literacy Z score = 0.5726+0.265*x

-10 -8 -6 -4 -2 0 2 4LFPT ASIN Z SCORE

-3

-2

-1

0

1

2

Average

Average NAPLAN Literacy Z score = 0.5054+0.1976*x

-10 -8 -6 -4 -2 0 2 4R FPT ASIN Z SCORE

-3

-2

-1

0

1

2

Average

WARP Z SCORE = 0.0871+0.2002*x

-10 -8 -6 -4 -2 0 2 4R FPT ASIN Z SCORE

-3

-2

-1

0

1

2

WA

RP

Z SC

OR

E

WARP Z SCORE = 0.1039+0.2143*x

-10 -8 -6 -4 -2 0 2LFPT ASIN Z SCORE

-3

-2

-1

0

1

2

WA

RP

Z SC

OR

E

WARP Z SCORE = 0.2969+0.2647*x

-10 -8 -6 -4 -2 0 2 4LDD ASIN Z Score

-3

-2

-1

0

1

2

WA

RP

Z SC

OR

E

WARP Z SCORE = 0.0602+0.205*x

-10 -8 -6 -4 -2 0 2 4RDD ASIN Z Score

-3

-2

-1

0

1

2

WA

RP

Z SC

OR

E

Listening Capability Score = 0.2085+0.2417*x

-10 -8 -6 -4 -2 0 2 4LDD ASIN Z Score

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

Listening Capability Score = -0.0343+0.2005*x

-10 -8 -6 -4 -2 0 2 4RDD ASIN Z Score

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

Listening Capability Score = -0.0218+0.1664*x

-10 -8 -6 -4 -2 0 2 4LFPT ASIN Z SCORE

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

Listening Capability Score = -0.068+0.1102*x

-10 -8 -6 -4 -2 0 2 4R FPT ASIN Z SCORE

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

19

Page 20: Testing Central Processing Disorders

Test score sensitivity relative to functional abilities Gaps in noise - left Gaps in noise - right Digit span - Forward Digit span - Reversed

List

enin

g ca

pabi

litie

s Re

adin

g flu

ency

Dani Tomlin

Lite

racy

Listening Capability Score = -0.124+0.2894*x

-1.6-1.4

-1.2-1.0

-0.8-0.6

-0.4-0.2

0.00.2

0.40.6

0.81.0

1.2

L Gin Z score

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Cap

Listening Capability Score = -0.1261+0.2162*x

-3.0 -2.5 -2.0 -1.5 -1.0 -0.5 0.0 0.5 1.0 1.5R Gin Z score

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

Listening Capability Score = -0.0312+0.4149*x

-2.5 -2.0 -1.5 -1.0 -0.5 0.0 0.5 1.0 1.5 2.0DS FW Z SCORE

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

Listening Capability Score = -0.0199+0.5467*x

-2.0 -1.5 -1.0 -0.5 0.0 0.5 1.0 1.5 2.0DS Rev Z Score

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

Average NAPLAN Literacy Z score = 0.4358+0.6129*x

-2.0 -1.5 -1.0 -0.5 0.0 0.5 1.0 1.5 2.0DS Rev Z Score

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

NA

PLA

N Lite

Average NAPLAN Literacy Z score = 0.454+0.5643*x

-2.0 -1.5 -1.0 -0.5 0.0 0.5 1.0 1.5DS FW Z SCORE

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Average

Average NAPLAN Literacy Z score = 0.3701-0.1306*x

-3.0 -2.5 -2.0 -1.5 -1.0 -0.5 0.0 0.5 1.0 1.5R Gin Z score

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Average

Average NAPLAN Literacy Z score = 0.3754-0.2565*x

-0.6 -0.4 -0.2 0.0 0.2 0.4 0.6L Gin Z score

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Average

WARP Z SCORE = -0.006+0.5397*x

-1.6-1.4

-1.2-1.0

-0.8-0.6

-0.4-0.2

0.00.2

0.40.6

0.81.0

1.2

L Gin Z score

-3

-2

-1

0

1

2

3

WA

RP

Z SC

OR

E

WARP Z SCORE = 0.0099+0.3944*x

-3.0 -2.5 -2.0 -1.5 -1.0 -0.5 0.0 0.5 1.0 1.5R Gin Z score

-3

-2

-1

0

1

2

3

WA

RP

Z SC

OR

E

WARP Z SCORE = 0.0673+0.541*x

-2.5 -2.0 -1.5 -1.0 -0.5 0.0 0.5 1.0 1.5 2.0DS FW Z SCORE

-3

-2

-1

0

1

2

3

WA

RP

Z SC

OR

E

WARP Z SCORE = 0.0897+0.7375*x

-2.0 -1.5 -1.0 -0.5 0.0 0.5 1.0 1.5 2.0DS Rev Z Score

-3

-2

-1

0

1

2

3

WA

RP

Z SC

OR

E 20

Page 21: Testing Central Processing Disorders

Test score sensitivity relative to functional abilities LiSN-S Low Cue LiSN-S High cue attention

List

enin

g ca

pabi

litie

s Re

adin

g flu

ency

Dani Tomlin

Lite

racy

WARP Z SCORE = 0.0719+0.2626*x

-5 -4 -3 -2 -1 0 1 2 3LC Sdev from avg

-3

-2

-1

0

1

2

WA

RP

Z SC

OR

E

WARP Z SCORE = 0.1186+0.3258*x

-5 -4 -3 -2 -1 0 1 2 3HC Sdev from avg

-3

-2

-1

0

1

2

WA

RP

Z SC

OR

E

Average NAPLAN Literacy Z score = 0.4274+0.3453*x

-5 -4 -3 -2 -1 0 1 2 3LC Sdev from avg

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Average

Average NAPLAN Literacy Z score = 0.4454+0.3003*x

-5 -4 -3 -2 -1 0 1 2 3HC Sdev from avg

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Average

Listening Capability Score = 0.0843+0.56*x

-5 -4 -3 -2 -1 0 1 2 3LC Sdev from avg

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

Listening Capability Score = 0.0332+0.3098*x

-5 -4 -3 -2 -1 0 1 2 3HC Sdev from avg

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

MLD z score

Listening Capability Score = -0.0792-0.0256*x

-3 -2 -1 0 1 2 3 4 5MLD Z score

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

WARP Z SCORE = 0.0107+0.0001*x

-3 -2 -1 0 1 2 3 4 5MLD Z score

-3

-2

-1

0

1

2

WA

RP

Z SC

OR

E

Average NAPLAN Literacy Z score = 0.3523+0.0132*x

-3 -2 -1 0 1 2 3 4 5MLD Z score

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Average

Average NAPLAN Literacy Z score = 0.4196+0.274*x

-6 -5 -4 -3 -2 -1 0 1 2Attention Quotient Z score

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Average

WARP Z SCORE = 0.2157+0.2121*x

-6 -5 -4 -3 -2 -1 0 1 2Attention Quotient Z score

-3

-2

-1

0

1

2

WA

RP

Z SC

OR

E

Listening Capability Score = 0.188+0.2352*x

-6 -5 -4 -3 -2 -1 0 1 2Attention Quotient Z score

-2.5

-2.0

-1.5

-1.0

-0.5

0.0

0.5

1.0

1.5

2.0

Listening Ca

21

Page 22: Testing Central Processing Disorders

Sensitivity: Effect on outcome variable of being 1 SD below the mean on test score -0.2 0 0.2 0.4 0.6 0.8 1

TONI

Digit Span Rev

Digit Span Fwd

LiSN-S Low cue

L GIN

Lisn-S High cue

L DD

R GIN

Attention

L FPT

R DD

R FPT

MLD

Listening capabilitiesLiteracyReading ability

22

Page 23: Testing Central Processing Disorders

Correlations – outcomes and test scores Liter

acy WAR

P

Listen

Cap L DD R DD L FPT R

FPT MLD L GIN R GIN

LiSN LC

LiSN HC

LiSN SA

DS Fwd

DS Rev TONI Att

Literacy - 0.60 0.77 0.66 0.41 0.49 0.46 0.03 -0.12 -0.07 0.39 0.34 -0.03 0.56 0.67 0.62 0.49

WARP 0.60 - 0.64 0.47 0.33 0.34 0.37 0.00 0.25 0.22 0.21 0.34 0.09 0.44 0.56 0.51 0.32

Listening Cap

0.77 0.64 - 0.47 0.37 0.34 0.26 -0.04 0.14 0.13 0.43 0.32 0.15 0.34 0.43 0.53 0.35

L DD 0.66 0.47 0.47 - 0.47 0.46 0.37 -0.12 0.08 0.14 0.28 0.25 0.13 0.53 0.48 0.49 0.27

R DD 0.41 0.33 0.37 0.47 - 0.27 0.35 -0.17 0.09 0.11 0.22 0.14 0.14 0.33 0.33 0.30 0.22

L FPT 0.49 0.34 0.34 0.46 0.27 - 0.87 -0.12 0.00 -0.03 0.12 0.07 0.17 0.29 0.42 0.38 0.19

R FPT 0.46 0.37 0.26 0.37 0.35 0.87 - -0.12 0.11 0.01 0.12 0.11 0.22 0.26 0.36 0.37 0.08

MLD 0.03 0.00 -0.04 -0.12 -0.17 -0.12 -0.12 - -0.17 -0.19 0.03 -0.08 0.06 0.05 -0.07 -0.02 -0.03

L GIN -0.12 0.25 0.14 0.08 0.09 0.00 0.11 -0.17 - 0.73 -0.02 0.02 0.12 0.04 0.04 -0.04 -0.09

R GIN -0.07 0.22 0.13 0.14 0.11 -0.03 0.01 -0.19 0.73 - -0.05 0.02 0.18 0.05 0.09 0.08 -0.04

LiSN LC 0.39 0.21 0.43 0.28 0.22 0.12 0.12 0.03 -0.02 -0.05 - 0.26 -0.04 0.30 0.21 0.28 0.08

LiSN HC 0.34 0.34 0.32 0.25 0.14 0.07 0.11 -0.08 0.02 0.02 0.26 - 0.43 0.09 0.16 0.24 0.06

LiSN SA -0.03 0.09 0.15 0.13 0.14 0.17 0.22 0.06 0.12 0.18 -0.04 0.43 - 0.02 0.08 0.14 -0.02

DS Fwd 0.56 0.44 0.34 0.53 0.33 0.29 0.26 0.05 0.04 0.05 0.30 0.09 0.02 - 0.59 0.30 0.11

DS Rev 0.67 0.56 0.43 0.48 0.33 0.42 0.36 -0.07 0.04 0.09 0.21 0.16 0.08 0.59 - 0.38 0.31

TONI 0.62 0.51 0.53 0.49 0.30 0.38 0.37 -0.02 -0.04 0.08 0.28 0.24 0.14 0.30 0.38 - 0.23

Attention 0.49 0.32 0.35 0.27 0.22 0.19 0.08 -0.03 -0.09 -0.04 0.08 0.06 -0.02 0.11 0.31 0.23 -

P<0.01

23

Page 24: Testing Central Processing Disorders

NAPLAN literacy

1 2 3 4 5 6 7 8 9 10 11 12

L DD * * * * * * * * * * *

R DD * * * * * *

L FPT * * * * * * * *

R FPT * * * * * * * * *

MLD *

L GIN * * * *

R GIN * * * * * * * * * *

DS Fwd * *

DS Rev * * * * * * * * * * * *

LiSN LC * * * * *

LiSN HC * * * * *

LiSN SA * * * * * 24

Page 25: Testing Central Processing Disorders

What is affecting listening capabilities? TONI

DS Fwd

DS Rev

Att

LDD Listening

capabilities

0.27

0.10

0.19

0.10

0.20

25

N=59 Adj R2 = 0.31

Page 26: Testing Central Processing Disorders

What is affecting literacy? TONI

DS Fwd

DS Rev

Att

LDD NAPLAN Literacy

0.24

0.30

0.18

0.16

0.29

But only 14 clinic participants with NAPLAN so far.

26

N=35 Adj R2 = 0.64

Page 27: Testing Central Processing Disorders

Importance of the presenting symptoms?

FOLL

none

LEAR

ATTN/C

ON

C

Attention

READ

ING

LANG

UAG

E

Spelling/WPrimary Concern

05

101520253035404550

No of observations

27

Page 28: Testing Central Processing Disorders

Importance of presenting symptoms

LDD ASIN Z Score LFPT ASIN Z SCORE L Gin Z score DS FW Z SCORE DS Rev Z Score LC Sdev from avg TONI Z Score

FOLLOWING INSTLEARNING DIFFIC.

ATTN/CONCREADING

Primary Concern

-4.0-3.5-3.0-2.5-2.0-1.5-1.0-0.50.00.51.01.5

MANOVA analysis: p=0.94

28

Page 29: Testing Central Processing Disorders

Importance of presenting symptoms

Child fails to understand an

instruction

Acts (inappropriately) based on what

was heard

Asks for repetition of instruction

Does nothing

Misbehaves

Event Response by child

Interpretation by observer

Daydreams

Badly behaved

Can’t follow instructions

Is not very smart

Poor concentration

29

Page 30: Testing Central Processing Disorders

Experiment 2

Pia Gyldenkaerne current PhD study

• Children referred to Macquarie Uni Audiology Clinic due to suspected APD (n=119)

• Teachers, parent, speech pathologist referral

• Age range of 7–13 years

30

Page 31: Testing Central Processing Disorders

Measures obtained • Dichotic Digits Test (DDT): Binaural integration (Musiek, 1993) • Frequency Pattern Test (FPT): Temporal sequencing (Musiek et al, 1990) • Gaps in Noise (GIN): Temporal resolution (Musiek et al, 2005) • MLD: Binaural interaction (Bellis, 2003)

• Memory CELF-4: Forward and reverse digits • Attention: BrainTrain®: Continuous Performance Test: Sustained auditory

and visual attention • Cognition -TONI-4: Nonverbal cognitive assessment

• Questionnaire: – Purpose designed – yes/no answers to 18 questions asking about difficulties in listening

and its possible consequences

• Academic Performance: WARP (reading fluency)

31

Page 32: Testing Central Processing Disorders

Test score sensitivity relative to functional ability: Reported difficulties and reading fluency

-12 -10 -8 -6 -4 -2 0 2

FPT_R_SD

-2

0

2

4

6

8

10

12

14

Reported D

ifficulties

-12 -10 -8 -6 -4 -2 0 2

FPT_L_SD

-2

0

2

4

6

8

10

12

14

Reported D

ifficulties

-5 -4 -3 -2 -1 0 1 2

DDT_R_SD

-2

0

2

4

6

8

10

12

14

Reported D

ifficulties

-7 -6 -5 -4 -3 -2 -1 0 1 2

DDT_L_SD

-2

0

2

4

6

8

10

12

14

Reported D

ifficulties

Dichotic digits - left Dichotic digits - right Freq pattern - left Freq pattern - right

Repo

rted

diff

icul

ties

Read

ing

spee

d

-12 -10 -8 -6 -4 -2 0 2 4

FPT_R_SD

0

20

40

60

80

100

120

140

160

180

200

220

WA

RP

Average

-12 -10 -8 -6 -4 -2 0 2

FPT_L_SD

0

20

40

60

80

100

120

140

160

180

200

220

WA

RP

Average

-6 -4 -2 0 2 4

DDT_R_SD

0

20

40

60

80

100

120

140

160

180

200

220

WA

RP

Average

-7 -6 -5 -4 -3 -2 -1 0 1 2 3

DDT_L_SD

0

20

40

60

80

100

120

140

160

180

200

220

WA

RP

Average

Pia Gyldenkaerne and Mridula Sharma 32

Page 33: Testing Central Processing Disorders

Test score sensitivity relative to functional ability: Reported difficulties and reading speed

Gaps in noise - right

-7 -6 -5 -4 -3 -2 -1 0 1 2

MLD_SD

-2

0

2

4

6

8

10

12

14

Reported D

ifficulties

Binaural masking level difference

0 20 40 60 80 100 120

BT Response Control Quotient

-2

0

2

4

6

8

10

12

14

Reported D

ifficulties

0 20 40 60 80 100 120 140

BT Attention Quotient

-2

0

2

4

6

8

10

12

14

Reported D

ifficulties

234567891011

GIN Right

-2

0

2

4

6

8

10

12

14

Reported D

ifficulties

Brain Train attention quotient

Brain Train response control quotient

-7 -6 -5 -4 -3 -2 -1 0 1 2

MLD_SD

0

20

40

60

80

100

120

140

160

180

200

220

WA

RP

Average

0 20 40 60 80 100 120 140

BT Response Control Quotient

0

20

40

60

80

100

120

140

160

180

200

220W

AR

P A

verage

0 20 40 60 80 100 120 140

BT Attention Quotient

0

20

40

60

80

100

120

140

160

180

200

220

WA

RP

Average

234567891011

GIN Right

0

20

40

60

80

100

120

140

160

180

200

220

WA

RP

Average

Repo

rted

diff

icul

ties

Read

ing

spee

d

Pia Gyldenkaerne and Mridula Sharma 33

Page 34: Testing Central Processing Disorders

Simple correlation matrix – outcome scores and test scores

Reported Difficulties WARP L DDT R DD L FPT R FPT R GIN MLD TONI

BT Attention Quotient

Reported Difficulties - -0.57 -0.49 -0.24 -0.42 -0.44 0.28 0.11 -0.55 -0.35

WARP -0.57 - 0.41 0.20 0.35 0.41 -0.33 -0.07 0.35 0.50

L DDT -0.49 0.41 - 0.43 0.42 0.49 -0.20 0.01 0.31 0.36

R DDT -0.24 0.20 0.43 - 0.22 0.23 -0.11 -0.00 0.07 0.27

L FPT -0.42 0.35 0.42 0.22 - 0.86 -0.28 -0.05 0.34 0.22

R FPT -0.44 0.41 0.49 0.23 0.86 - -0.33 -0.06 0.33 0.26

R GIN 0.28 -0.33 -0.20 -0.11 -0.28 -0.33 - 0.01 -0.05 -0.02

MLD 0.11 -0.07 0.01 -0.00 -0.05 -0.06 0.01 - 0.12 0.04

TONI -0.55 0.35 0.31 0.07 0.34 0.33 -0.05 0.12 - 0.41

BT Attention Quotient

-0.35 0.50 0.36 0.27 0.22 0.26 -0.02 0.04 0.41 -

P<0.01

34

Page 35: Testing Central Processing Disorders

No.

of p

redi

ctor

s

DDT_

L_SD

DDT_

R_SD

FPT_

L_SD

FP

T_R_

SD

MLD

_SD

GIN

_R

BT.A

ttQ

uot

TON

I.Quo

t

1 * 2 * * 3 * * * 4 * * * * 5 * * * * * 6 * * * * * * 7 * * * * * * * 8 * * * * * * * *

No.

of p

redi

ctor

s

DDT_

L_SD

DDT_

R_SD

FPT_

L_SD

FPT_

R_SD

MLD

_SD

GIN

_R

BT.A

ttQ

uot

1 * 2 * * 3 * * * 4 * * * * 5 * * * * * 6 * * * * * * 7 * * * * * * *

Reported Difficulties

35

Page 36: Testing Central Processing Disorders

History Audiometry

Is there a problem that CAPD

might explain?

Exclude CAPD; Refer elsewhere

No

Current approach to CAPD testing

Detailed test battery

Yes

Test result interpretation Non-specific remediation and management: • Classroom placement • FM use • Instruction style • Soundfield amplification • Auditory training software

Page 37: Testing Central Processing Disorders

Questionnaire Audiometry Measured disability

Is there a problem that CAPD

might explain?

Detailed test battery

Exclude CAPD; Refer elsewhere

No

Dealing with problems in understanding speech

Master test battery

Yes

Non-specific remediation and management: • Classroom placement • FM use • Instruction style • Soundfield amplification

Test result interpretation leading to a disorder-specific diagnosis

Disorder-specific remediation

Page 38: Testing Central Processing Disorders

Questionnaire Audiometry Measured disability

Is there a problem that CAPD

might explain?

Detailed test battery

Exclude CAPD; Refer elsewhere

No

Dealing with problems in understanding speech

Master test battery

Yes

Non-specific remediation and management: • Classroom placement • FM use • Instruction style • Soundfield amplification

Test result interpretation leading to a disorder-specific diagnosis

Disorder-specific remediation LiSN & Learn

LiSN-S High Cue

LiSN-S Spatial

Advantage

LiSN-S Talker

Advantage

LiSN-S Low Cue

SPD Undiag- nosed deficit

Pitch deficit

FPT Verbal

FPT Hum

SPIN Hi Cont

SPIN Lo Cont

Closure skill

deficits ?

Top-down training ?

Page 39: Testing Central Processing Disorders

Criteria for adopting a CAPD test

• Test is associated with variation in functional ability – High sensitivity (= ∆ 𝐹𝐹𝐹𝐹𝐹𝐹𝐹𝐹𝐹𝐹 𝑧−𝑠𝐹𝐹𝑠𝑠

∆ 𝐶𝐶𝐶𝐶 𝑧−𝑠𝐹𝐹𝑠𝑠)

– Deviant results common in clinical population – Attributes tested minimally shared with other tests in battery

• Leads to a specific diagnosis, for which remediation exists, and remediation affects real life functional ability

• Time taken is small • Test is minimally affected by attention, intelligence,

motivation, working memory, and language ability • Known high reliability and critical differences • Associated with a known anatomical site and/or neural

mechanism

39

Page 40: Testing Central Processing Disorders

Comparison of tests against criteria LiSN-S LC/SA

Dichotic digits

Freq Patt Test

GIN Digit span fwd

Digit span

reverse

MLD

Sens: slope re functional 4 3 2 3 5 6 0 Sens: deviant results common

2 7 5 2 2 2 0

Uniqueness re other tests 3 6.5 2 2.5 0 12 0 Specific diagnosis leading to effective proven remediation

0/10 0 0 0 0 0 0

Time taken

Minimal effect of attention, working memory, intelligence, motivation, language ability

5/15 3 3 16 3 5 25

Known high reliability and small critical differences

10 ? ? ? ? ? ?

Known anatomical site and neural mechanism

0 1 0 0 0 0 5 40

Page 41: Testing Central Processing Disorders

Test structure???? Parental / teacher report

of difficulties

LiSN - HC

LiSN remainder

DD

Att TONI

DS rev

Psych

Psych Psych

Low

Strategies, FM

Low Low

Low

SA low: LiSN&Learn HC low: Strategies, FM

Low

Strategies, FM

41

Page 42: Testing Central Processing Disorders

www.NAL.gov.au

42

Page 43: Testing Central Processing Disorders

Auditory processing

neurons

Deficient auditory skill

Life consequences

Trauma or failure to develop Visual

processing neurons

Deficient visual skill

Life consequences

Consequent disabilities

Detection of an APD in the presence of hearing loss

43

Page 44: Testing Central Processing Disorders

LiSN-S Prescribed Gain Amplifier

44

Page 45: Testing Central Processing Disorders

0 10 20 30 40 50 60

4FAHL in worse ear (dB HL)

-22

-20

-18

-16

-14

-12

-10

-8

-6

-4

-2

0

2

4

6

8

Speech reception thre

Different voices 90 Same voices 90 Different voices 0 Same voice 0

Helen Glyde and Sharon Cameron

Bett

er

Changes in LiSN-S scores with hearing loss

45