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Delivering Sustainable Long-term
Growth in Agriculture
Jim Collins, Executive Vice President
Bank of America Merrill Lynch – Global Agriculture and Chemicals Conference
March 3, 2016
2
Forward-Looking Statements This document contains forward-looking statements which may be identified by their use of words like “plans,” “expects,” “will,” “believes,”
“intends,” “estimates,” “anticipates” or other words of similar meaning. All statements that address expectations or projections about the future,
including statements about the company’s strategy for growth, product development, regulatory approval, market position, anticipated benefits
of recent acquisitions, timing of anticipated benefits from restructuring actions, outcome of contingencies, such as litigation and environmental
matters, expenditures and financial results, and timing of, as well as expected benefits, including synergies, from proposed merger with The
Dow Chemical Company and intended post-merger separations, are forward looking statements. Forward-looking statements are not
guarantees of future performance and are based on certain assumptions and expectations of future events which may not be realized.
Forward-looking statements also involve risks and uncertainties, many of which are beyond the company’s control. Some of the important
factors that could cause the company’s actual results to differ materially from those projected in any such forward-looking statements are:
fluctuations in energy and raw material prices; failure to develop and market new products and optimally manage product life cycles; ability to
respond to market acceptance, rules, regulations and policies affecting products based on biotechnology and, in general, for products for the
agriculture industry; outcome of significant litigation and environmental matters, including realization of associated indemnification assets, if
any; failure to appropriately manage process safety and product stewardship issues; changes in laws and regulations or political conditions;
global economic and capital markets conditions, such as inflation, interest and currency exchange rates; business or supply disruptions;
security threats, such as acts of sabotage, terrorism or war, natural disasters and weather events and patterns which could affect demand as
well as availability of products for the agriculture industry; ability to protect and enforce the company’s intellectual property rights; successful
integration of acquired businesses and separation of underperforming or non-strategic assets or businesses; and risks related to the
agreement entered on December 11, 2015, with The Dow Chemical Company pursuant to which the companies have agreed to effect an all-
stock merger of equals, including the completion of the proposed transaction on anticipated terms and timing, the ability to fully and timely
realize the expected benefits of the proposed transaction and risks related to the intended business separations contemplated to occur after
the completion of the proposed transaction. The company undertakes no duty to update any forward-looking statements as a result of future
developments or new information.
Major Product Groups
Corn seeds 46%
Soybean seeds 15%
Other seeds 8%
Insecticides 14%
Herbicides 10%
Fungicides 7%
U.S. & Canada 55%
EMEA 21%
Latin America 15%
Asia Pacific 9%
• Sales: $9,798
• Segment operating earnings: $1,646
• Segment operating earnings margin:17%
2015 Results ($ in millions)
Growth Strategies
• Extend germplasm leadership and drive biotech
pipeline
• Deliver one new, innovative compound to crop
protection pipeline annually, on average
• Leverage integrated product offers across
leading go-to-market models
• Grow in core markets of NA, Brazil and Europe;
expand in targeted emerging markets
Agriculture Segment - Overview Pioneer, Crop Protection
3
• Achieve cost savings and operating
earnings commitments
• Deliver the new product pipeline
• Close the merger, plan for synergies and
prepare for intended separations*
Priorities
Regions
* Subject to approval of DowDuPont board.
Long-term Sustainable Demand for Grain
Strong Despite Near-term Challenges
4
200
9
202
0
203
0
Emerging Middle Class
Global Trends
C&S America N. America
Asia-Pacific
Europe
M.E. & Africa
1.8 Bil (27% of 6.8 Bil)
3.2 Bil (42% of 7.7 Bil)
4.9 Bil (58% of 8.4 Bil)
• Population growth in an expanding middle class
• Consumer demand for improved diets
• Limited increase in land for ag production
• Need for increased ag productivity
Data Source: United Nations, OECD and USDA.
$1
$2
$3
$4
$5
$6
$7
00/0
1
01/0
2
02/0
3
03/0
4
04/0
5
05/0
6
06/0
7
07/0
8
08/0
9
09/1
0
10/1
1
11/1
2
12/1
3
13/1
4
14/1
5
15/1
6e
Historic range
from mid-70s
U.S. Farm Price for Corn ($/Bu)
4 years of below-trend
yields drove prices to
unsustainable levels
Current normal
range after biofuels
increase
4
Agriculture Segment - 2016 Outlook Pioneer, Crop Protection
5
1,732
1,550
• Sector to remain challenged
• Farmer net returns continue to trend down
• Commodity prices at the low end of new normal
• Volatile currency markets will present headwinds
• Slight uptick in Brazil Safrinha and North America
corn planted area
• Highly competitive seed and chemistry market
• Weak demand for soybean insecticides in Brazil
• Elevated seed and crop protection inventories
• Cost reductions and productivity improvements
• Currency headwinds
• Modest improvement in 2016 NA corn demand
• Lower crop protection and soybean seed volumes
2015 2016 Est. 0
2,000
4,000
6,000
8,000
10,000
12,000
$ in
Millio
ns
2015 2016 Est. 0
500
1,000
1,500
2,000
$ in
Millio
ns
Mid-single digits percent lower;
about flat ex-currency
Flat; up ~10% ex-currency
2016 Market Dynamics
2016 Financial Drivers
Currency
impact
Sales
Currency
impact
Segment Operating Earnings
Innovation Pipeline Poised to Deliver in Both
the Near-term and Long-term
6
Pioneer
Corn insect control Leptra® corn hybrids +
Dermacor® in Brazil
Qrome™ corn
hybrids*
Optimum® GLY
canola*
T Series soybeans
EncircaSM Services
Crop
Protection
New MOA -
Nematicide
Cyazypyr® insect control
Improved Hybrid
Rice Technology
Roundup Ready 2
Xtend™ technology*
*Pending regulatory approvals
Recent
Launches 2017-18 Beyond
New corn genetics
2016
New MOA –
Disease Control
Next gen soybeans
Dermacor® seed treatment
Lumivia™ seed treatment
Zorvec™ disease control
Lumisena™ seed treatment*
Pyraxalt™ insect control*
Vessarya™ disease control*
6
Historical Avg. 2013-2016*100-113 CRM germplasm pipeline
• Doubled Haploids
• Genome Wide Selection
• Precision Phenotyping
2x Increase*
Leveraging new
enabling
technologies into
the future:
• CRISPR-Cas
• Next Gen Analytics
• Advanced
Phenotyping
Rate of Gain
Optimum® AQUAmax®
The Drought Leader
Category % Yield
Adv.
Bu/ac
Yield
Adv.
%
Wins
# of
Comps
Water-limited +6.2% +6.3 66% 5,486
Favorable +1.1% +2.4 55% 72,340
2011-2015 on-farm performance
Increased Scale & Quality
Breeding Pipeline
2010 2016
Elite Germplasm
Industry-leading traits
Trait Integration
1.5x
Bigger
Benefits Optimum
® AQUAmax
®
Hybrid Benefits
Competitive Drought
Hybrid
7
Leader in Germplasm and Breeding Improved Performance Today from Advanced Breeding Technologies
Leveraging Germplasm Globally
Genome Editing Enabled by CRISPR-Cas Advanced Breeding Technology to Accelerate Innovation
8
Great genetics
Sensitive to stress
100% B
Poor agronomics
Resistant to stress
Move/Edit
Native Genes 100% A
Great genetics &
Resistant to stress
Fewer cycles and Elite Genetics vs.
5-7 cycles through backcrossing
Hybridization
Expect first products to market
in as early as 5 years Products, benefits and concepts described herein will not be offered for sale or distribution until completion of field testing and
applicable regulatory reviews.
Accelerated Rate of Innovation
CRISPR-Cas
Soybean Output Traits
Yield
Disease Resistance
Drought Tolerance
Increased Nutritional Value
CRISPR-Cas has numerous
agricultural applications
New Corn Genetics – A Step Change in Yield 2016 North America Corn Leaders
9
Qrome®
*Pending regulatory approvals
Qrome®
4.3
8.4
6.0 6.3 4.8
17.2
11.0 12.2
10.9 10.5 9.1
4.5 5.2
10.1
7.9
4.4 3.5
8.9
0
5
10
15
20Y
i
e
l
d
A
d
v
a
n
t
a
g
e
Source: 2015 Pioneer on-farm trial database. Customer comparisons based on 2015 yield results including data from weigh wagon and PKP trials for all Pioneer® brand hybrids against all competitors.
Individual results may vary. All data weighted by comparisons within 4CRM and adjusted to 15% moisture. Product performance is variable and subject to any number of environmental, disease and pest
pressures.
World Record
of 532 bu/acre
190
195
200
205
Legacy Products Qrome™ Products
Yie
ld (
Bu
/Acre
)
R&D Phase – 4 Pre-Launch
D 1 2 3 4 L
Qrome™ Product Research Plot Strong Efficacy & Agronomics | Above- & Below-
Ground Insect Protection
10
*Pending regulatory approvals
Pioneer® brand Qrome™ products will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews.
0
10
20
30
40
50
2015 2020P
erc
en
t
Pioneer Triple Stack
Mix Percent
• Unlocks full potential for higher-yielding corn hybrids with
above- and below-ground protection
• Enables Pioneer® brand triple-stack product mix to
increase by 10 percentage points by 2020
• Strengthens Pioneer’s yield performance in corn rootworm
areas; improves competitive position
• Enables rapid transition to multiple modes-of-action for
below-ground insect protection
• Expected launch as early as 2017*
Benefits Benefits
4-7
bu/ac
Yield Improvement Over
Legacy Triple-Stacks
Qrome™ Corn Hybrids High Yield Potential with Proven Insect Protection
2016
Ear
Protection
Vegetative
Protection
Control
Hybrid
Leptra®
Hybrid
11
2014 Southern U.S. Launch
2015/16 Brazil Safrinha Launch
• Unique Stack of Three Traits for Above-ground Insect
Control
• Helps protect against a broad spectrum of insects,
including fall armyworm
• Protects the high yield potential and grain quality of
superior Pioneer genetics
• Improves competitiveness and value of Pioneer corn
hybrids in Brazil
• One of the fastest technology ramp-ups in Pioneer history
- Approaching one-third of 2016 summer season sales
in Brazil
• Offered with the additional protection of DuPont
Dermacor® seed treatment to optimize yield
Benefits Benefits
R&D Phase – Launch
D 1 2 3 4 L
Leptra® Corn Hybrids Improved Insect Protection in Brazil
ENHANCED YIELD & TRAIT
DURABILITY
• Above- and below-ground protection
and integrated refuge
• Multiple modes of action
- Optimum® Leptra® hybrids
- Qrome™ products
• Consistent high performance across a
wide range of environments
• Maximized yields
• Expanded focus on maximizing yields
including nitrogen use-efficiency
CORN R&D PHASE MARKETS
(●) PRIMARY
MARKET
OPPORTUNITY (MM ACRES)
Est.
Peak
Sales
D 1 2 3 4 L NA EU LA AP AF <50 50-100 >100 H / M / L
HIGHLIGHTED PRODUCT CONCEPTS
Optimum® Leptra® hybrids ● ● H
Qrome™ products ● H
BIOTECH SOLUTIONS
New MOA Lepidopteran Protection III ● ● ● ●
New MOA Coleopteran Protection III ●
Drought Tolerance II ●
Yield & Yield Stability ●
Benefits Focus
12
R&D Phases D=Discovery, 1=Proof of Concept, 2=Early Development, 3=Advanced Development, 4=Pre-Launch
Launch=Available for commercial sale or use
Market Opportunity Market Opportunity reflects total acres in Primary Markets in millions
Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L= $0-100MM, M= $100-500MM, H= $500MM+ | Indicates advancement or addition (2/15-2/16).
Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the lead event for each program. Discovery and market
evaluation is an ongoing process for all programs in the pipeline.
Corn Biotech Pipeline Strong Pipeline of Insect Protection and Agronomic Traits
T Series Soybeans – Improved Yield Performance 2016 North America Soybean Leaders
13 *Pending regulatory approvals
Qrome®
0.4 0.4 0.5
0.8
2.4
0.4
1.2
3.9
2.9
1.4
3.1 2.7
2.3
1.4 1.1
3.3
2.3 2.3
0
1
2
3
4
5Y
i
e
l
d
A
d
v
a
n
t
a
g
e
Source: 2015 Pioneer on-farm trial database. Customer comparisons based on 2015 yield results including data from weigh wagon and PKP trials for all Pioneer® brand varieties compared against all
competitors. Individual results may vary. All data weighted by comparison within 3RM. Product performance is variable and subject to any number of environmental, disease and pest pressures.
† Per United Soybean Board
*Limited Launch: Full commercialization upon global regulatory approvals.. 14
• Soybeans that will benefit
processors, livestock producers and
consumers
• Plenish® high oleic soybeans have a
first-to-market advantage
- 15-20 million acre market
opportunity in the U.S.†
- Yields on par with Pioneer® brand
elite commercial varieties
- Highest oleic content in soybean;
20% less saturated fat than
commodity soybean oil
- Enhanced functionality for food
preparation and industrial
applications
• Rich pipeline of soybean output traits
for high-growth vegetable oil and
animal feed markets
Benefits Benefits
R&D Phase – Limited Launch*
D 1 2 3 4 L* D 1 2 3 4 L
R&D Phase – 2 Early Development
Commodity Soybean
Plenish® High Oleic Soybeans Increased Oil & Improved Meal Value
57.4
Linoleic Linolenic Sats Oleic
Oleic
Oleic
Soybean Output Traits Soybeans with Consumer Benefits & Increased Feed Value
• Increased End-Use Value
- Plenish® High Oleic Soybeans
- Increased Soybean Oil &
Improved Meal Value
• Herbicide Tolerance
- Roundup Ready 2 Xtend™ trait
- LibertyLink® trait
• Plant protection addressing key
insect and disease pests for major
markets
SOYBEAN R&D PHASE MARKETS
(●) PRIMARY
MARKET OPPORTUNITY
(MM ACRES)
Est. Peak Sales
D 1 2 3 4 L NA EU LA AP AF <50 50-100 >100 H / M / L
HIGHLIGHTED PRODUCT CONCEPTS
Plenish® High Oleic Soybeans^ ● M
Multiple Mode Herbicide Tolerance ● ● H
BIOTECH SOLUTIONS
Increased Soybean Oil & Improved
Meal Value
● ●
Lepidopteran Protection ●
Hemipteran Protection ●
Asian Soybean Rust Resistance ●
Benefits Focus
15
R&D Phases D=Discovery, 1=Proof of Concept, 2=Early Development, 3=Advanced Development, 4=Pre-Launch
Launch=Available for commercial sale or use
Market Opportunity Market Opportunity reflects total acres in Primary Markets in millions
Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L= $0-100MM, M= $100-500MM, H= $500MM+ | Indicates advancement or addition (2/15-2/16).
Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the lead event for each program. Discovery and market
evaluation is an ongoing process for all programs in the pipeline.
Soybean Biotech Pipeline Delivering Herbicide Tolerance and Increased End-Use Value
R&D Phases D=Discovery, 1=Proof of Concept, 2=Early Development, 3=Advanced Development, 4=Pre-Launch
Launch=Available for commercial sale or use
Market Opportunity Market Opportunity reflects total acres in Primary Markets in millions
Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L= $0-100MM, M= $100-500MM, H= $500MM+ | Indicates advancement or addition (2/15-2/16).
Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the lead event for each program. Discovery and market
evaluation is an ongoing process for all programs in the pipeline.
• Increased canola market
access with:
- Higher yields
- Out-licensing
- Expanded application
window
• Expanding hybrid rice
and hybrid wheat product
offerings with strong
agronomics
ADDITIONAL
CROPS
R & D
PHASE MARKETS
(●) PRIMARY
MARKET
OPPORTUNITY (MM ACRES)
Est.
Peak
Sales
D 1 2 3 4 L NA EU LA AP AF <50 50-100 >100 H / M / L
CANOLA
Optimum® GLY Herbicide Tolerance ● ● M
Herbicide Tolerant Canola with the
LibertyLink® trait
●
L
Herbicide Tolerant Canola with the
Optimum® GLY & LibertyLink® trait stack
●
L
RICE
Hybrid Rice Technology II ●
Dual Mode of Action Lepidopteran
Protection
●
WHEAT
Hybrid Wheat Technology ●
Benefits Focus
16
Additional Crops Biotech Pipeline Herbicide Tolerant Options in Canola and Hybrid Rice and Wheat
17
EncircaSM Yield Nitrogen
Management Service
Yes 68% Yes 87%
No
32% No
%
YIELD
+6 bpa
YIELD
NITROGEN
-5 lbs N
• Pioneer Agronomy Expertise
• Soil analysis and Decision Zones
• Hyper-local Weather Network
• Advanced Crop/Nitrogen Models
• Strong Grower Adoption • Nitrogen Management Service paid for
on over 1 MM acres in 2015
• Growers have shared > 75 MM acres
of field boundaries with Pioneer
*Source: 2015 DuPont Pioneer research trials. 77% of customers who used EncircaSM Yield Nitrogen
Management Service improved profitability over traditional practices. Average return of $30 per acre
before service fee based on input cost savings and grain market prices for individual winning trials.
Source: 2015 DuPont Pioneer on-farm trials.
Comprehensive Fee-based Services
Manage Information
• EncircaSM View Premium
Manage Inputs
• EncircaSM Yield Nitrogen
Management Service
• EncircaSM Yield Stand
• EncircaSM Yield Fertility
Built on the DuPont Pioneer
Leading Route-to-Market
$30 per acre average
return on investment*
EncircaSM Services Decision Services Leader Built on Pioneer’s Direct Customer Access
Insect Control Solutions in Crop Protection Targeting $2 Billion in Combined Peak Sales*
18
DuPont™ Rynaxypyr®
Insect Control
New DuPont™ Pyraxalt™
Insect Control**
• Sold in 110 countries in 2015
• ~ $1 billion in sales
in 2015
• Growing into new market
segments and distribution
channels
• Investing to lower COGS
• Additional products in insect
control portfolio building on
success
• Novel activity for control of wide
spectrum of hopper insects in rice
in Asia
• New standard for high-potency low-
use rate, and favorable
environmental profile
• Registration dossiers submitted in
key rice countries; first sales
expected 2018
• Leveraging recent experience in
other insect control launches; wide
distribution and accelerated
adoption in key markets
• Launched in >30 countries including
Brazil, China, India, Japan, U.S. and
Canada
• Cross-spectrum with potential to
reduce number of applications
• Enhances produce quality and
marketable yield for fruit and
vegetables
• Accelerating ramp-up in India,
Japan, Brazil & US
• EU registrations expected in
2017/18
• Investing in new market spaces
(both crops and pests)
Continued market share growth in
AP, EMEA, NA
The next game changer for Insect
Control in AP Rice Creating exceptional Grower Value
*DuPontTM PyraxaltTM is not registered for use or sale in the United States and other countries. No offer for sale, sale or use of these products are permitted prior to the
issuance of the country level registration.
DuPont™ Cyazypyr®
Insect Control
*Includes sales from seed treatment.
Disease Control Solutions in Crop Protection Targeting $1 Billion in Combined Peak Sales*
19
DuPont Picoxystrobin
Disease Control
DuPont Penthiopyrad
Disease Control
DuPont™ Zorvec™
Disease Control**
• Strobilurin of choice for Asian
Soybean Rust in soybean, rust in
cereals, corn, rice and specialty
diseases
• Sold in over 50 countries including
Brazil, US, EU, China, India
• Developing next generation
mixtures: Vessarya™ and
Aproach® Power
• Improving performance by
introducing new formulations in
soybean, corn, cereals, oilseed
rape and rice
• Excellent control of septoria and
specialty crop diseases (e.g. apple
scab)
• Registered & launched in over 25
countries
• Expanding in new crops, disease
and mixtures globally.
• 2016 planned launches and
expansion in new cereals markets
in Eastern Europe
• Unmatched Oomycete control in
potato, grapes and vegetables
• Novel mode of action
• Excellent environmental profile, low
use rate
• Consistent, long-lasting control
• 2016 Launches: China, Japan,
Mexico, Colombia, Australia,
Vietnam, Argentina
• Part of DuPont™ Lumigen™
(Lumnisena™) seed sense in corn,
soybean and sunflower
Growing in new markets
and with mixtures
New >$100M sales potential in
cereals, fruits and vegetable market
Game changer in $2B blight and
downy mildew market
**DuPontTM ZorvecTM is not registered for use or sale in the United States. No offer for sale, sale or use of these products are permitted prior to the issuance of the country level
registration.
*Includes sales from seed treatment.
Seed Treatment – Expanding into New Markets Targeting $400 Million in Combined Peak Sales
20
DuPont™ Dermacor®
Insecticide Seed Treatment
DuPont™ Lumiderm™
Insecticide Seed Treatment
DuPont™ Lumivia™
Insecticide Seed Treatment
• Used on over 5 MM acres of
soybean in Brazil in 2015
• Excellent above & below ground
insect protection for plant vigor and
yield
• Full registration on soybean & corn
• Launched on corn in Brazil & Mexico
in 2015
• Exceeded expectations in 2015
season by achieving >8%
penetration in canola acres in
Canada
• Enhanced insect protection enables
higher yields
• Better protection from cutworms and
flea beetles results in superb early
season vigor
• Continued expansion in U.S. China
launched in 2015
• Improved yield advantage of 2.6
bushels/acre through enhanced
insect protection*
• Available in the US on the newest
Pioneer® brand hybrids
2016 target: 30% + volume growth 2016 target: 30% + volume growth 2016 target: double 2015 acreage
Lumiderm™
+ Standard Standard Dermacor® Standard
*Source: 2013-2014 DuPont Pioneer research trials,160 locations, 59.4% positive yield response.
R&D Phases D=Discovery 1=Proof of Concept 2=Early Development
3=Advanced Development 4=Pre-Launch Launch=Available for commercial
sale or use
Products, concepts, or benefits described herein will not be offered for sale or
distribution until completion of field testing and applicable regulatory reviews.
Each Phase represents only the lead event for each program. Discovery and
market evaluation is an ongoing process for all programs in the pipeline.
Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L= $0-100MM, M= $100-
500MM, H= $500MM+ | Indicates advancement or addition (2/15-2/16).
* Target Market information updated March 28, 2016.
Benefits Focus
DuPont Crop Protection Pipeline Sustainable Growth and Innovation Through a Highly Productive Pipeline
ONE OF THE MOST PRODUCTIVE
AND INNOVATIVE PIPELINES IN THE
INDUSTRY
FOCUSED RESEARCH
• Target to deliver one commercial
candidate each year to the pipeline
• Emphasis on novel modes of action
and new classes of chemistry
• Successful renewal of existing
technologies
NEAR TERM LAUNCHES
BUILDING ON SUCCESS OF
RYNAXYPYR® AND CYAZYPYR®
• New seed treatment solutions
• DuPont™ Zorvec™ disease control
launch
• DuPont™ Pyraxalt™ insect control in
rice expected in the next few years
Advanced
Advanced
21
PROGRAM R&D Phase Target Market (shaded) Est.
Peak
Sales D 1 2 3 4 L F&V Rice Cereals Corn Oil
Seeds
WEED CONTROL
New mode of action grass and
broad leaf weed control
New class of grass and broad leaf
weed control
INSECT and NEMATODE CONTROL
New class of insect control for
piercing/sucking pests
Broad spectrum nematicide, new
mode of action M
Pyraxalt™, new class of insect
control for piercing pests M
Cyazypyr® cross-spectrum insect
control M
Lumivia™ (part of Lumigen™
Seed Sense) M
Lumiposa™ (part of Lumigen™
Seed Sense) L
DISEASE CONTROL
Broad-spectrum disease control,
new mode of action
Zorvec™ oomycete control, new
mode of action* M
Penthiopyrad broad-spectrum
disease control M
Lumisena™ (part of Lumigen™
Seed Sense) L
Advanced
Advanced
Advanced
Integrated Seed and Crop Protection Solutions
23
• World’s leading production agriculture business
with most comprehensive, balanced and
diverse seed and crop protection portfolio with
exceptional opportunity for growth
• Rich history and sustainable commitment to
production agriculture focused on delivering
solutions to growers around the world
• Robust innovation pipeline of germplasm,
biotech traits and crop protection technologies
that enable the delivery of a broader suite of
stronger products to the market
• Enhanced scale and multiple routes-to-market
allow broader reach of complementary
offerings and enable deeper customer intimacy
that will drive increased grower productivity
and profitability globally
1. This product is fully approved in the U.S. and Canada. Traits included in these products
may or may not be approved in all global markets.
Cro
p P
rote
cti
on
G
erm
pla
sm
/ T
rait
s
Seed Brands Traits
Insecticides Herbicides Fungicides
Other Emerging
Technologies
Specialty
Insect
Control
Portfolio
Sulfonylureas Indoxacarb
Pyroxsulam
Picoxystrobin
1
Advanced Technologies
Combines Portfolios of Leading Products With Strong Capabilities Driving Future growth
Ag Co: World-Leading, Comprehensive Agriculture Business Most Comprehensive and Diverse Seed and Crop Protection Portfolio
APPENDIX 1:
3/28/2016 24
Biotech Trait R&D
25
Discovery
Select product target Define targets based on current and anticipated future customer needs, and advancing scientific capabilities.
Identify leads Screen potential genes to find a gene or combination of genes that demonstrate efficacy against the target.
Phase 1
Proof of concept
Crop transformation Insert gene leads into target crop.
Demonstrate proof of concept Test genes to confirm efficacy against the target.
Gene and construct optimization Evaluate genes and constructs for trait efficacy and agronomic performance in the target market environment. Optimize for trait and stack performance.
Phase 2
Early development
Production transformation Insert constructs into target crop to generate multiple events.
Event characterization Select best events across germplasm and environments.
Event Development Expand field testing of candidate commercial lead events across stacked trait and germplasm combinations.
Initiate regulatory testing Start regulatory studies, including method development & validation.
Early trait introgression Breed events into a broader set of elite germplasm.
Phase 3
Advanced development
Advanced field testing Further characterize lead commercial events across germplasm and environments and select event(s) for regulatory submission.
Regulatory testing Complete regulatory studies for primary markets.
Regulatory dossier submission Submit extensive data package and analysis to authorities.
Phase 4
Pre-launch
Regulatory testing Complete regulatory studies for additional submissions (e.g. stacks).
Trait introgression and seed ramp up Breed trait into elite germplasm across maturities and intensify ramp-up of seed quantities.
Pre-marketing Prepare customer education plans. Perform market testing. Prepare commercial seed volumes.
IMPACT™ trials Field test new products in development near the customer. Focus interactions to deliver Right Product on Right Acre following commercialization.
Launch
Regulatory approvals Receive all regulatory approvals for launch cultivation.
Commercial sales begin Pioneer works customer-by-customer and market-by-market to deliver the Right Product on the Right Acre tailored to individual grower needs.
Product stewardship Continue ongoing stewardship practices which began in research. These include education and communication to ensure compliance with regulations, Pioneer policies and crop management strategies.
DuPont Pioneer R&D is Committed to Delivering
Superior Germplasm, Traits and Trait Combinations in
the Most Productive Products for Our Customers.
Our Advanced Biotech Pipeline Programs Are an
Integral Part of Our Approach as We Deliver the Right
Product on the Right Acre
Agrisure® and Agrisure Viptera® are registered trademarks of, and used under license from, a Syngenta Group Company. Agrisure® technology incorporated into these seeds is commercialized under a license from
Syngenta Crop Protection AG. Herculex® Insect Protection technology by Dow AgroSciences and Pioneer Hi-Bred. Herculex® and the HX logo are registered trademarks of Dow AgroSciences LLC. Liberty®, LibertyLink® ,
and the Water Droplet Design are registered trademarks of Bayer. YieldGard®, the YieldGard Corn Borer design, Roundup Ready®, Xtend™ and Genuity® are trademarks of Monsanto Technology LLC used under license.
ALWAYS READ AND FOLLOW PESTICIDE LABEL DIRECTIONS. Roundup Ready® crops contain genes that confer tolerance to glyphosate, the active ingredient in Roundup® brand agricultural herbicides. Roundup®
brand agricultural herbicides will kill crops that are not tolerant to glyphosate.
Pioneer is a member of Excellence Through Stewardship® (ETS). Pioneer is a member of Excellence Through Stewardship® (ETS). Pioneer products are commercialized in accordance with ETS Product Launch
Stewardship Guidance and in compliance with the Pioneer policies regarding stewardship of those products. Crops and materials containing biotech traits may only be exported to or used, processed, or sold in jurisdictions
where all necessary regulatory approvals have been granted for those crops and materials. It is a violation of national and international laws to move materials containing biotech traits across borders into jurisdictions
where their import is not permitted. Growers should discuss these issues with their purchaser or grain handler to confirm the purchaser or handler's position on products being purchased. Excellence Through
Stewardship® is a registered trademark of the Biotechnology Industry Organization.
^ EXPORT APPROVAL NOTICE: This product is fully approved in the United States and Canada. Traits included in these products may or may not be approved in all global markets; therefore, the combination of these
traits and the grain and certain by-products (including oil, dried distillers grain, cobs, and husks) from THESE PRODUCTS MAY NOT BE APPROVED for all markets. Growers that use this product are required and agree
to adhere to the stewardship requirements as outlined in the Pioneer Product Use Guide and product-specific Stewardship Requirements for this product, which include specific grain disposition requirements. For
questions regarding product stewardship and biotech traits please contact your sales representative or refer to www.pioneer.com/stewardship. Growers are required to discuss trait acceptance and grain channeling policies
with their local grain handler prior to delivering grain containing biotech traits.
Pioneer® brand soybeans with the Roundup Ready 2 XtendTM technology will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Dicamba herbicide is not currently
approved for commercial in-crop use with soybeans with the Roundup Ready 2 Xtend™ technology and nothing herein is a promotion or an offer to sell dicamba herbicide for this use. It is a violation of federal law to
promote or offer to sell unregistered pesticides or a registered pesticide for an unregistered use.
Pioneer® brand Qrome™ products will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews.
Product performance in water-limited environments is variable and depends on many factors such as the severity and timing of moisture deficiency, heat stress, soil type, management practices and environmental stress
as well as disease and pest pressures. All products may exhibit reduced yield under water and heat stress. Individual results may vary.
.
®, SM, TM Trademarks and service marks of DuPont, Pioneer or their respective owners. © 2016 PHII.
^
26
APPENDIX 2:
DOWDUPONT MERGER OF EQUALS
3/28/2016 27
Disclaimer
Important Information About the Transaction and Where to Find It
28
Important Information About the Transaction and Where to Find It
In connection with the proposed transaction, on March 1, 2016 DowDuPont Inc. (f/k/a Diamond-Orion HoldCo, Inc.) (“DowDuPont”), filed with the Securities and
Exchange Commission (“SEC”) a preliminary registration statement on Form S-4 that includes a joint proxy statement of The Dow Chemical Company (“Dow”)
and E. I. du Pont de Nemours and Company (“DuPont”) and that also will constitute a prospectus of DowDuPont. These materials are not final and may be
amended. Dow, DuPont and DowDuPont may also file other documents with the SEC regarding the proposed transaction. This document is not a substitute for
the joint proxy statement/prospectus or definitive registration statement or any other document which Dow, DuPont or DowDuPont may file with the SEC.
INVESTORS AND SECURITY HOLDERS OF DOW AND DUPONT ARE URGED TO READ THE PRELIMINARY REGISTRATION STATEMENT, THE JOINT
PROXY STATEMENT/PROSPECTUS AND THE DEFINITIVE VERSIONS THEREOF AND ANY OTHER RELEVANT DOCUMENTS THAT ARE FILED OR
WILL BE FILED WITH THE SEC, AS WELL AS ANY AMENDMENTS OR SUPPLEMENTS TO THESE DOCUMENTS, CAREFULLY AND IN THEIR
ENTIRETY BECAUSE THEY CONTAIN OR WILL CONTAIN IMPORTANT INFORMATION ABOUT THE PROPOSED TRANSACTION AND RELATED
MATTERS. Investors and security holders may obtain free copies of the preliminary materials filed on March 1, 2016 and the definitive versions of these
materials and other documents filed with the SEC (when available) by Dow, DuPont and DowDuPont through the web site maintained by the SEC at
www.sec.gov or by contacting the investor relations department of Dow or DuPont at the following:
Dow DuPont
2030 Dow Center 974 Centre Road
Midland, MI 48674 Wilmington, DE 19805
Attention: Investor Relations Attention: Investor Relations
+1 989-636-1463 +1 302-774-4994
Participants in the Solicitation
Dow, DuPont, DowDuPont and their respective directors and executive officers may be deemed to be participants in the solicitation of proxies in respect of the
proposed transaction. Information regarding Dow’s directors and executive officers, including a description of their direct interests, by security holdings or
otherwise, is contained in Dow’s Form 10-K for the year ended December 31, 2015, its proxy statement filed on March 27, 2015 and the joint proxy
statement/prospectus of Dow contained in the Form S-4, which are filed with the SEC. Information regarding DuPont’s directors and executive officers,
including a description of their direct interests, by security holdings or otherwise, is contained in DuPont’s Form 10-K for the year ended December 31, 2015, its
proxy statement filed on March 23, 2015 and the joint proxy statement/prospectus of DuPont contained in the Form S-4, which are filed with the SEC. A more
complete description will be available in the definitive registration statement on Form S-4 and the joint proxy statement/prospectus.
No Offer or Solicitation
This communication is not intended to and shall not constitute an offer to sell or the solicitation of an offer to sell or the solicitation of an offer to buy any
securities or a solicitation of any vote of approval, nor shall there be any sale of securities in any jurisdiction in which such offer, solicitation or sale would be
unlawful prior to registration or qualification under the securities laws of any such jurisdiction. No offer of securities shall be made except by means of a
prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended.
Disclaimer Cont’d
Important Information About the Transaction and Where to Find It
29
Cautionary Notes on Forward Looking Statements
This communication contains “forward-looking statements” within the meaning of the federal securities laws, including Section 27A of the Securities Act of 1933, as amended,
and Section 21E of the Securities Exchange Act of 1934, as amended. In this context, forward-looking statements often address expected future business and financial
performance and financial condition, and often contain words such as “expect,” “anticipate,” “intend,” “plan,” “believe,” “seek,” “see,” “will,” “would,” “target,” similar expressions,
and variations or negatives of these words. Forward-looking statements by their nature address matters that are, to different degrees, uncertain, such as statements about the
consummation of the proposed transaction and the anticipated benefits thereof. These and other forward-looking statements, including the failure to consummate the proposed
transaction or to make or take any filing or other action required to consummate such transaction on a timely matter or at all, are not guarantees of future results and are subject
to risks, uncertainties and assumptions that could cause actual results to differ materially from those expressed in any forward-looking statements. Important risk factors that
may cause such a difference include, but are not limited to, (i) the completion of the proposed transaction on anticipated terms and timing, including obtaining shareholder and
regulatory approvals, anticipated tax treatment, unforeseen liabilities, future capital expenditures, revenues, expenses, earnings, synergies, economic performance,
indebtedness, financial condition, losses, future prospects, business and management strategies for the management, expansion and growth of the new combined company’s
operations and other conditions to the completion of the merger, (ii) the ability of Dow and DuPont to integrate the business successfully and to achieve anticipated synergies,
risks and costs and pursuit and/or implementation of the potential separations, including anticipated timing, any changes to the configuration of businesses included in the
potential separation if implemented, (iii) the intended separation of the agriculture, material science and specialty products businesses of the combined company post-mergers
in one or more tax efficient transactions on anticipated terms and timing, including a number of conditions which could delay, prevent or otherwise adversely affect the proposed
transactions, including possible issues or delays in obtaining required regulatory approvals or clearances, disruptions in the financial markets or other potential barriers, (iv)
potential litigation relating to the proposed transaction that could be instituted against Dow, DuPont or their respective directors, (v) the risk that disruptions from the proposed
transaction will harm Dow’s or DuPont’s business, including current plans and operations, (vi) the ability of Dow or DuPont to retain and hire key personnel, (vii) potential
adverse reactions or changes to business relationships resulting from the announcement or completion of the merger, (viii) uncertainty as to the long-term value of DowDuPont
common stock, (ix) continued availability of capital and financing and rating agency actions, (x) legislative, regulatory and economic developments, (xi) potential business
uncertainty, including changes to existing business relationships, during the pendency of the merger that could affect Dow’s and/or DuPont’s financial performance, (xii) certain
restrictions during the pendency of the merger that may impact Dow’s or DuPont’s ability to pursue certain business opportuni ties or strategic transactions and (xiii)
unpredictability and severity of catastrophic events, including, but not limited to, acts of terrorism or outbreak of war or hostilities, as well as management’s response to any of
the aforementioned factors. These risks, as well as other risks associated with the proposed merger, are more fully discussed in the joint proxy statement/prospectus included
in the preliminary registration statement on Form S-4 filed with the SEC in connection with the proposed merger. While the list of factors presented here is, and the list of factors
presented in the preliminary registration statement on Form S-4 are, considered representative, no such list should be considered to be a complete statement of all potential
risks and uncertainties. Unlisted factors may present significant additional obstacles to the realization of forward looking statements. Consequences of material differences in
results as compared with those anticipated in the forward-looking statements could include, among other things, business disruption, operational problems, financial loss, legal
liability to third parties and similar risks, any of which could have a material adverse effect on Dow’s or DuPont’s consolidated financial condition, results of operations, credit
rating or liquidity. Neither Dow nor DuPont assumes any obligation to publicly provide revisions or updates to any forward looking statements, whether as a result of new
information, future developments or otherwise, should circumstances change, except as otherwise required by securities and other applicable laws.
Third Party Information
This website may contain or refer to news, commentary and other information relating to Dow, DuPont or DowDuPont generated by, or sourced from, persons or companies
that are not affiliated with Dow, DuPont or DowDuPont. The author and source of any third party information and the date of its publication are clearly and prominently identified.
Dow, DuPont and DowDuPont have neither sought nor obtained permission to use or quote such third party information. Dow, DuPont and DowDuPont have not assisted in the
preparation of the third party information, cannot guarantee the accuracy, timeliness, completeness or availability of the third party information, and do not explicitly or implicitly
endorse or approve such information.
Copyright © 2014 DuPont or its affiliates. All rights reserved. The DuPont Oval Logo, DuPont™, The miracles of science™ and all products denoted with ™ or ® are registered trademarks or trademarks of E. I. du Pont de Nemours and Company or its affiliates.
Images reproduced by E. I. du Pont de Nemours and Company under license from the National Geographic Society.
Copyright © 2016 DuPont. All rights reserved. The DuPont Oval Logo, DuPontTM, The miracles of scienceTM, and all products denoted with ® or TM are trademarks or registered trademarks of and all services marked with SM are service marks of E. I. du Pont de Nemours and Company.
+Images reproduced by E. I. du Pont de Nemours and Company under license from the National Geographic Society.
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