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Blastocyst culture and transfer procedure for In-Vitro Fertilisation (IVF) facilitates selection of best quality embryos for transfer to the uterus of the mother. The concept of embryo quality is very important. With Blastocyst embryo transfer, it is possible to transfer fewer embryos, reducing the risk of multiple pregnancies while keeping overall pregnancy rates high.



BLASTOCYST CULTURE

Blastocyst culture is a technique to grow embryos beyond the third day of culture. Typically, in an IVF setting, the transfer of embryos into the uterus happens three days after the egg retrieval when the embryos generally are between six and eight cells. When the embryo is cultured to day five, it has around 120 cells which is known as a Blastocyst. As the newly-formed embryo develops, it moves slowly towards the uterine cavity where it would ultimately implant. This process takes approximately six to seven days. When the embryo reaches the ‘Blastocyst’ stage, it is ready to be implanted.



Why should we consider Blastocyst transfer?

In certain patients, the advantage of Blastocyst culture allows optimal selection of embryos for transfer, resulting in an increased implantation rate per embryo transferred.

The main advantage is that fewer embryos need to be transferred to eliminate the possibility of triplet pregnancies, while maintaining a high pregnancy rate.



Is it for everyone?

No. Generally speaking, this procedure should be limited to patients with excessive numbers of embryos (greater than 10) in which case, further selection of embryos beyond the day three stage would be advantageous. As a general rule, patients under the age of 37 are considered ideal for this technique. This is not recommended to older patients.



• What percentage of embryos will grow to the Blastocyst stage in culture?

For younger patients, up to 50% of all embryos will grow to the Blastocyst stage.

• Are there any limitations to Blastocyst culturing?Yes, if you have fewer than four, eight-cell quality embryos on

the third day of culture, Blastocyst culturing is not recommended even if you desire it.



Would the embryos that arrest in culture prior to the Blastocyst stage have arrested in the uterus?

There is no clear-cut way to know this answer. Embryos that do not survive in culture would be less likely to survive or implant in the uterus.

In-vitro Fertilisation and its resultant treatment options such as Intra cytoplasmic sperm injection, egg donation, embryo donation and surrogacy have helped millions of Infertile couples from across the world to have their own genetic baby in the last 30 years and is considered perhaps the most ground-breaking advancement in science in this century.



ContactDr. Pratima Grover, Kiran Infertility Centre Pvt Ltd, Khairatabad, Hyd.For appointment, call 040 - 42020394SMS - 9948175768.Email [email protected] : www.kiranivfgenetic.com



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