Bacterial Antigens

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Discussion about why Bacteria have antigens.

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  • 1. Bacterial AntigensBy, Prajwal Keranahalli

2. Definition A Bacterial Antigen is a molecule that is foundon the surfaces of bacterial organisms When detected by the human body B cellscreate Antibodies to mark remaining bacteriafor destruction. 3. Main Immune Cells Macrophages B Cells Memory B Cells 4. Types of Antibodies Primary Antibodies Gathered from animals like Mice, rabbits, etc. Secondary Antibodies Can be tagged with fluorescent markers to determineprotein localization 5. Why Do Bacteria Have Antigens?The human body uses antibodies as a primary way to fightoff bacterial infection. Antibodies work by binding toantigen identifier proteins on the membranes of theseorganisms. So why do so many types of bacteria still haveantigens if they just make themselves more noticeable totheir hosts.Antigens may be used for inter-bacterial communicationbut wouldn't the advantage of surviving eventuallyoutweigh the benefit of interaction. I say this becausebacteria are inherently unicellular organisms and so groupcoordination is not a primary goal for these organisms. 6. Quorum SensingAutoinducersBonnie Bassler Ted Talk: http://tinyurl.com/nt67z9u 7. Possibility 1The point of the adaptive immune system is that it canin theory react to any molecular structure conceivablewithout necessitating the germ-line genome to containa huge load of information of microbial targets.Therefore it is quite slow which gives bacteria sometime to act. 8. Possibility 2The detected antigens/patterns in question are highlyconserved within bacteria, because the proteins thatconstitute these patterns are critical for the survival ofany bacterium as an organismFlagella 9. Possibility 2The detected antigens/patterns in question are highlyconserved within bacteria, because the proteins thatconstitute these patterns are critical for the survival ofany bacterium as an organismFlagella