Open Science: A year of progress

William Gunn, Ph.D. Head of Academic Outreach

@mrgunn

The Cost of Knowledge

13K signed

Tools of scientific discovery

Clean energy Clean water

Sustainable food supplies

Pandemic diseases

Terrorist violence

Climate change

US National Academies “Grand Challenges”:

Artificial Intelligence

“The state of knowledge of the human race is sitting in the scientists’ computers, and is currently not shared […] We need to get it unlocked so we can tackle those huge problems.”

A Big Problem

...and aggregates research data in the cloud

Mendeley extracts research data…

Mendeley makes science more collaborative and transparent:

Install Mendeley Desktop

..helps researchers work smarter

..makes science more collaborative

and transparent ..is creating a massive open

database of research

Tools of scientific discovery

Mendeley...

300 million documents uploaded 2.0 million users

Cambridge Stanford University MIT Imperial College London University of Oxford Harvard University University of Michigan University College London University of California at Berkeley Columbia University

It’s Open!

http://www.isitopendata.org/enquiry/view/43bcbda2-30ef-486b-9c52-4378ede75c7d/

Mashups with data on:

Chemical compounds

Locations

Alzheimer’s research

Grant funding

Twitter streams

Open API

Quantity Quality

What’s Next?

We didn’t see that a target is

more likely to be validated if it

was reported in ten publications

or in two publications NATURE REVIEWS DRUG DISCOVERY 10, 712 (SEPTEMBER 2011)

Either the results were reproducible

and showed transferability in other

models, or even a 1:1 reproduction of

published experimental procedures

revealed inconsistencies between

published and in-house data NATURE REVIEWS DRUG DISCOVERY 10, 712 (SEPTEMBER 2011)

Select relation:

supports refutes complements uses same data ...

Human-curated, constantly evolving,

linked scientific database

www.mendeley.com