OME™: Mobile Cognitive Healthcarefor the Consumer

Michael Nova, M.D.Chief Innovation OfficerPathway Genomics

90 OF ALL THE WORLD’S DATA BIG DATA AND ‘OMICSIN MEDICINE

WAS CREATED IN THE LAST 2 YEARS

DOUBLES EVERY 3 YEARS,

%

MEDICAL INFORMATION

and by 2020 will double every 3 days.

DATA IS WORTHLESS… UNLESS IT CANBE ANALYZEDAND ACTED ON.

Wholegenome

sequence

All the word’s recorded music

as of 2011

Library of congress digital holdings as

of 2012

Weather modeling anticipated to produce first single-discipline

exabyte dataset

In 2010 the world produced 1.27b

IS BIG (DATA)?HOW BIG

A Single Person’sHEALTH DATA

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…”a single person will generate 1 million gigabytes (1 Terabyte) of health-related data across his or her lifetime. That’s as much data as in 300 million books.” Rob Merkel, IBM, 2015

Big Data Healthcare Cost Saving

Healthcare TRANSFORMATION

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We believe Healthcare Transformation revolves around three business trends and two key opportunities for differentiation…

Evolution of Care Delivery

Data + EcosystemConvergence

Movement to Consumerism

Game Changing Analytical Insight “What should I do?”

Flexible Adoption of Business Models Mobile, TeleHealth, Cognitive

TREN

DSO

PPO

RTU

NIT

IES

The HumanGENOME AND MEDICAL DATA

8

22,000 GENES6 BILLION DNA LETTERS 49

CHROMOSOMES$1,000COST TO SEQUENCE

OF PATIENT’S PERMANENT HEALTH RECORD IS MADE UP OF CLINICAL LABORATORY T E S T D A T A

70%

HealthcareTRENDS

9

Healthcare Costs Driven by Obesity74% of all costs are confined to obesity and related conditions

Mobile TechAN APP FOR THE HUMAN GENOME

1111

“killer app will connect genetic variants to environmental, lifestyle, dietary, and activity related factors, guiding both sick and healthy people towards a fundamentally better quality of life..”

Source: Apple Healthcare, 2015

Source: Topol, 2014

PROBLEM SPACE IN HEALTHCARE

UNDERSTANDING &RELATING MANY DATA SETS

The New Era OfCognitive Computing and A.I.

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• 1956-Dartmouth AI Conference

• Fast CPU/VPU• Hierarchical

Algorithms

• Weak AI• Strong AI (AGI)• Deep

Learning• Supervised• Unsupervise

d

COGNITIVE HEALTHCARE

CLINICAL, FITNESSAND WELLNESS

OMEDIGITAL HEALTH

PLATFORM

AND DEEP LEARNING

™

WHAT A CONSUMER WANTS FOR HEALTHCARE

Plan A

Plan B

✔ ✔ ✔ ✔ ✔ ✔Content Needs

SHORT-TERM LONG-TERMMID-TERM

Understand my needs

Select my Doc or Benefit

Manage and Improve My Health

Get Health and Wellness Services

Get Health and Wellness Goods

Seek Information and Support

Trusting Health Apps

“In 2016, Users Will Trust Health Apps More Than Their Doctors...”(DEC 31, 2015 FORBES)

79 percent (%) of Americans said they would be willing to use a wearable device to manage their health

Other

Tools & Medication

Pregnancy

Sleep & Medication

Women's Health

Exercise

Weight Loss

8 Million

10.5 Million

26.5 Million

50 Million

18 Million

6 Million

7.5 Million

OF mHEALTH APPS (2014)

RISING POPULARITY

Source: Forbes 2015

US User #’s

APP Stores - #1 Distribution Channel

APP stores number one distribution channel for mHealth apps- MAW Feb 2016

“Distribution through other channels, such as via doctors, hospitals, or pharmacies are increasingly seen to be weaker channels through which to distribute a successful app solution.”

3.4 BILLION PEOPLE WORLDWIDE WILL OWN A SMARTPHONE

WILL USE HEALTH APPS

MARKET IN 2017mHEALTH

THE TOTAL GLOBAL mHEALTH MARKET WILL REACH $26 BILLION

½

What is OME?

Ome™ is the world’s first precision health and wellness mobile application using artificial intelligence (A.I.) and genetics to help provide consumers with precision information.

What is “cool” about AI/Cognitive and Healthcare?

• Biodata and NLP allows users to ask questions in everyday language that is translated into a Query to search for correct responses

• OME gets more accurate the more it is used; Dynamic Content

• We can accommodate client specific content (EHR, Genetic/WGS test, health survey, insurance); PHI is personal (HIPPA, etc.)

• Useful for many industries: Hospitals, Automotive, HR groups, Energy, Government, Telco, Hotels/Hospitality, etc¾ Employee safety, greater productivity, less

absenteeism, "precision" healthcare

CreatingPERSONALIZED RESULTS

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ENABLES YOU TOTAKE CHARGE

GATHERING AND CURATIONOME™ - USE INFORMATION

QUESTION:WHAT SHOULD I DO FOR MY WORKOUT TODAY?

ANSWER:YOU COULD GO FOR 2 MILE RUN IN CENTRAL PARK, TAKE 100MGS ADVIL AND DRINK ONE COFFEE FIRST (NO SUGAR), because of your CYP1A2 gene you are a slow metabolizer of caffeine, AND BE CLOSER TO EARNING 100 POINTS FROM VITALITY HEALTHCARE. BRING YOUR FITBIT. WHY DON’T YOU INVITE RUNNERDUDE100?

REAL TIMEEVENT ACTIONABILTY

OME™: IF YOU RUN 2 MILES TODAY YOU CAN ENJOY DINNER AT PAIZON’S MEDITERRANEAN, NEAR YOU NOW, AS PART OF YOUR DIET PLAN.

The FuturePATHWAY OME

The Pathway OME™ Mobile AppHealthcare Simplifiedwww.pathway.com

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Michael Nova M.D.

Chief Innovation OfficerPathway Genomics

Michael@Pathway.com