Hack Age Challenge

Hack Aging Challenge

ЦельВ кратчайшие сроки наполнить,проанализировать и визуализировать базу

данных препаратов с предполагаемойгеропротекторной активностью.

DATA MINING SCHEME

e-molecules, PubChem– Compound IUPAC name, CAS-number, general chemical properties

DRUG BANK, KEGG– General pharmaceutical dataADME SARfari– Additional bioactivity datathe Human Protein Atlas, EMBLexpression atlas

– Protein distribution in tissue/organ

DATA MINING SCHEME

ChEmbl– Molecule-protein interactionUniProt– Protein dataString db (STITCH)– Interaction networksOFFSIDES, Supertarget, ToxBase– Additional toxicity data

DATA MINING SCHEME

*Collect drug-protein interaction predictions based on chemical(drug) and genetic(protein) information.

*Generate smart semi-manual PubMed article search engine

(age-related or pathology-related epigenetic changes, lifespan researches)