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8/7/2019 AcuSolve Biomed Examples
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AcuSolve Examples – Blood PumpAcuSolve Examples – Blood Pump
n The power law blood damagemodel gives excellentagreement with the data.
Pressure contours on blade surfaces
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LVAD (heart pump!)LVAD (heart pump!)
n
ASAIO Journal – 2007Development and Validation of a Computational FluidDynamics
Methodology for Simulation of Pulsatile Left Ventricular AssistDevices
Authors: Richard B. Medvitz*‡, Eric G. Paterson*‡, James W. Kreider†, Keefe B.Manning†, Arnold A. Fontaine*†, Steven Deutsch*†
Institutional Affiliation: * Applied Research Laboratory, The Pennsylvania StateUniversity, University Park, Pa 16802
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Example of Mesh Motion for PumpExample of Mesh Motion for Pump
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Unstructured MeshUnstructured Mesh Computational velocity magnitude contours andComputational velocity magnitude contours andtangential velocity vectors at 6 mm from the fronttangential velocity vectors at 6 mm from the frontface of the LVAD with the mitral and aortic valvesface of the LVAD with the mitral and aortic valves
removedremoved..
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Blood/Cancer Cell InteractionBlood/Cancer Cell Interaction http://www.ensight.com/cutting-edge-cfd-simulations-take-cancer-http://www.ensight.com/cutting-edge-cfd-simulations-take-cancer-research-to-a-new-dimension.htmlresearch-to-a-new-dimension.html
Meghan Hoskins, a Ph.D. candidate in the Bioengineering program at PennState, under the advisement of Robert Kunz, Ph.D. and Cheng Dong,Ph.D., is examining how cancer cells stick to white blood cells, thedefenders of the blood stream, and how the flow of blood affects thisadhesion. Her work, funded by the National Cancer Institute and the PSU Applied Research Laboratory, is based on the theory that, as cancer cellstravel through the blood stream, they are attracted to areas where white
blood cells are at work fighting inflammation.
Cancer Cell
Traverseswhite blood cell
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Cell WorkflowCell Workflow
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Lung AirflowLung Airflow
Figure 1: Virtual 3-D Airway TreeGeometry
Model which has 54,611 branches
Figure 2 shows the wall pressure
distribution for that 3500 branches. Thescale on the model is -0.08 (blue) to 3.35(red) Pascals. Meshing and solving of thefull virtual model is currently underway
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Adominal Aortic AneurysmAdominal Aortic AneurysmN u m C r
国立がんセンター
がん予防・ 診研究セン検ター
山本 修司 先生
SPIE 2006
Pre-operative Post Operative
解析メッシュ 節点数 177,719 要素数 958,738 4節点四面体( amira 使用 )
領域分割数 1非定常解析
400 steps (4 心拍) 428 MB 11.1Hr
解析メッシュ 節点数 189,918 要素 1,015,905 4節点四面体( amira 使用 )
領域分割数 1非定常解析
400 steps (4 心拍) 456 MB 13.1 Hr
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N u m C r
The bloodstream analysis of the cerebral aneurysmThe bloodstream analysis of the cerebral aneurysm
inlet
outlet1
outlet2
outlet3
浜松医科大学
医学部放射線医学講座
礒田 治夫 先生
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N u m C rFlow Analysis in Cerebral AneurysmFlow Analysis in Cerebral Aneurysm ))
流線
解析メッシュ 節点数 90,398 要素数 385,490 4節点四面体( amira 使用 )
領域分割数 4非定常解析
300 steps (3 心拍) 69.6 MB/cpu
1.97 Hr
領域分割数 1189 MB6.87 Hr
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Animation of Flow in Aneurysms
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Blood fill from sending blood vesselBlood fill from sending blood vesselN u m C r
岐阜県立多治見病院心臓血管外科
徳田順之 先生
External Circulation from heart lung machine
送血管の例
4.1 l/min
The Gifu prefectural Tajimi hospitalheart blood vessel surgery
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Blood FillBlood Fill (( continuedcontinued ))
3.0 m/sec 2.0 m/sec 0.5 m/sec
Mesh Detailsnodes 321,678elements 1,806,203 (4 node tet)
Step1 : Steady State run for initial condition for Step 2Step2 : Transient DES Turb. Model
リスタート 100 steps
250 MB/CPU 5.9 Time
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Case StudyCase StudyPeristaltic PumpsPeristaltic Pumps
Ø Inert/Sterile FluidsInert/Sterile Fluids
Ø Biomedical devices to corrosive fluids in chemical industriesBiomedical devices to corrosive fluids in chemical industriesUses “peristalsis” processUses “peristalsis” process
Ø Tubing under compression causes fluid to flowTubing under compression causes fluid to flow
Ø As Tubing returns to natural state, flow is induced to the puAs Tubing returns to natural state, flow is induced to the pu
An FSI study is required to predict the pump flow characteristicsAn FSI study is required to predict the pump flow characteristics
Compr essi
onRestitution
Flow in
Flow out
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Peristaltic Pump ModelPeristaltic Pump Model
Structural ModelStructural ModelDynamic Explicit AnalysisDynamic Explicit Analysis
Flexible Hose Modelled as Rubber Flexible Hose Modelled as Rubber
Ø Hyperelastic propertiesHyperelastic properties
Ø CC1010
=69000, C=69000, C0101
=173000,=173000,
DD11=1.45e=1.45e-8-8
36828 Linear Hexahedral Elements36828 Linear Hexahedral Elements
Total solution time = 6.1 sTotal solution time = 6.1 s
Angular velocity: 10.472 radians/secAngular velocity: 10.472 radians/sec
Casing and rollers modelled as rigidCasing and rollers modelled as rigidØ Casing and ends are fixedCasing and ends are fixed
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Fluid ModelFluid ModelTransient analysisTransient analysis
Fluid properties to be viscous oilFluid properties to be viscous oilØ Density: 980 kg/mDensity: 980 kg/m33
Ø Viscosity: 0.5 kg/mViscosity: 0.5 kg/mss
Spalart-AllmarasSpalart-Allmaras turbulence modelturbulence model
72100 Linear Hexahedral Elements72100 Linear Hexahedral Elements
Inflow: Velocity-inlet conditionInflow: Velocity-inlet condition
Ø Initial stagnant conditionInitial stagnant condition
Outflow: Pressure-outlet conditionOutflow: Pressure-outlet conditionØ Outlet set to atmosphericOutlet set to atmospheric
pressurepressure
Peristaltic Pump ModelPeristaltic Pump Model
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Enabling FSI Solutions with Abaqus/CAEEnabling FSI Solutions with Abaqus/CAE
FSI module available for Abaqus/CAEFSI module available for Abaqus/CAE
Ø
Easy-to-use workflow for FSIEasy-to-use workflow for FSIModule provides specific functionality for defining FSI modulesModule provides specific functionality for defining FSI modules
CFD Product supportCFD Product support
Ø AcuSolveAcuSolve
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FSI WorkflowFSI Workflow
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Post-process the CFD SolutionPost-process the CFD Solution
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Post-process the FSI SolutionPost-process the FSI Solution
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ConclusionsConclusions
n AcuSolve is a powerful general purpose CFD codel
The premier commercial finite element based CFD solver l
n Major focusl Robustness
l Speed
l Accuracy
l Functionality
l Ease of usewith AcuConsole
l
n Ideal for engineering and scientific applications
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