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2000 alkaloids
alkaloidsU 0600
18 - 149Synthesis and CNS Activity of Tricyclic Theophylline Derivatives.8-Substituted Imidazo[2,1-f ]theophyllines. — Tricyclic theophyllinederivatives show sedative and analgesic activity. Derivative (VI) shows anti-serotonin and long-lasting hypothermic effects, whereas compound (VIII)is found to possess anticonvulsant activity. — (PAWLOWSKI, MACIEJ;DRABCZYNSKA, ANNA; KATLABI, JACEK; GORCZYCA, MARIA;MALEC, DANUTA; MODZELEWSKI, JERZY; Eur. J. Med. Chem. 34 (1999)12, 1085-1091; Dep. Pharm. Chem., Coll. Med., Jagiellonian Univ., PL-30-688Krakow, Pol.; EN)
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