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TECHNICAL COMMITTEE REPORTS
Committee on Statistics
PAUL WEHLING, CHAIR
General Mills, Inc., 330 University Ave SE, Minneapolis,
MN 55414
FOSTER D. MCCLURE, PAST CHAIR
U.S. Food and Drug Administration (retired), Frederick, MD
QIAN F. GRAVES, SECRETARY
U.S. Food and Drug Administration, Center for Food Safety
and Applied Nutrition, HFS-012, 5100 Paint Branch Pkwy,
College Park, MD 20740-3835
ROBERT A. LABUDDE
Least Cost Formulations Ltd, 824 Timberlake Dr, Virginia
Beach, VA 23464-3239
JUNG K. LEE
U.S. Food and Drug Administration, HFS-012, 5100 Paint
Branch Pkwy, College Park, MD 20740-3835
ZHICHAO LIN
U.S. Food and Drug Administration, 109 Holton St,
Winchester, MA 01890
JOHN G. PHILLIPS
U.S. Department of Agriculture, Agricultural Research
Service, Eastern Regional Research Ctr, 600 E. Mermaid
Ln, Wyndmoor, PA 19038-8551
STEPHEN SHERKEN
U.S. Food and Drug Administration (retired), Kensington,
MD 20895
Committee Activities
The Statistics Committee reviewers performed 25 reviews
on Official Methods of Analysis (OMA) submissions for
AOAC INTERNATIONAL this year. Of those, 14 were
original manuscripts and nine were revised manuscript reviews.
The Statistics Committee revised Appendix J and
Appendix K of the OMA Program Manual to conform to the
changes in Appendixes Q and R, which were made by the
Official Methods Board (OMB) previously.
The Statistics Review Training Outline Working Group
(Paul Wehling, Robert LaBudde, John Phillips, and Qian
Graves) met several times by teleconference and discussed
ways to train statistical reviewers to perform reviews on
collaborative protocols and manuscripts. The group is
working on training presentations for future Statistics
Committee members to share best practices.
LaBudde and Wehling have revised a proposal for
revisions of Appendix X of the OMA Program Manual which
they helped develop in July 2007. The proposed revisions to
the guidelines for validation of quantitative and qualitative
microbiological methods were intended primarily to clarify
the statistical procedures used in qualitative microbiological
methods. Wehling and LaBudde have contributed to the
development of guidelines for Biological Threat Agents. The
first guideline document was titled AOAC INTERNATIONAL
Methods Committee Guidelines for Validation of Bacterial
Threat Agent Methods and/or Procedures. Most of the
statistical treatments in this document were gleaned from the
proposed Appendix X revisions mentioned above.
Publications
McClure, F.D., & Lee, J.K. (2009) J. AOACInt. 92, 1593–1601
McClure, F.D., & Lee, J.K. (2009) J. AOAC Int. 92, 320–328
McClure, F.D., & Lee, J.K., (2008) J. AOAC Int. 91, 660–669
Nelsen, T.C., & Wehling, P. (2008) Cereal Foods World,
53, 285–288
Committee Organization
In order to better serve the needs of the Association as the
OMA process changes, committee members have decided to
reorganize the committee. For any standing Methods
Committees, the committee will still assign statistical advisors
to consult on study designs and perform OMA program
reviews. For smaller adhoc committees, the committee will
draw from two pools of advisors to be organized around the
type of method statistics used, either quantitative or
qualitative. The committee will assign new committee
advisors from the two pools as needed.
In addition, the committee will have a theoretical
“Methodology” subgroup that will discuss and debate current
issues in method validation and work to keep the guidelines
for method validation at the leading edge of statistical
methodology.
Quantitative statistics.—Phillips, Graves, LaBudde, and Zichao.
Qualitative statistics.—LaBudde, Wehling, Sherken, and
Zichao.
Methodology.—Graves, Lee, McClure, Phillips, Sherken,
and Wehling.
Current standing Methods Committee assignments are as
follows:
Committee on Pesticides and Disinfectant Formulations:
Jung Lee
Committee on Natural Toxins and Food Allergens:
Paul Wehling
Committee on Microbiology: Robert LaBudde and
Paul Wehling
Committee on Biological Threat Agents: Robert LaBudde
Committee on Antimicrobial Efficacy Testing:
Robert LaBudde
38B METHODS COMMITTEE REPORTS: JOURNAL OF AOAC INTERNATIONAL VOL. 93, NO. 1, 2010
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