Granulocytic Series

1

Nungruthai Nimnuch

School of Allied Health Sciences

Naresuan University Phayao

2Granulocytic series

3

Myeloblast

Promyelocyte

Eosinophilic

myelocyte

Eosinophilic

metamyelocyte

Eosinophilic

band form

Eosinophil

Basophilic

myelocyte

Basophilic

metamyelocyte

Basophilic band

form

Basophil

Neutrophilic

myelocyte

Neutrophilic

metamyelocyte

Neutrophilic

band form

Neutrophil

Neutrophilic seriesEosinophilic series Basophilic series

Granulocytic

series

Granulocytic

series

4

5

Size:- ��� ���������� 10-20 �����

Cytoplasm: -�)*�+�,����� --+� )./��+-���01 granuleNucleus:-���89:�,-�<-� �=��� Nucleus:Cytoplasm = 5:1 @A� 7:1-Chromatin �D��)��-01 nucleoli 2-5 �<

nucleoli

6

Size:- ��� ���������� 15-21 �����

Cytoplasm: - )./��+E�-�)*�+�,���A. -01 non-secific granules )��=�-G�� ��)��=�HAzurophilic granulesJ

Nucleus:-�)����K���,���9�L��)-chromatin ��)��-<=9�1�A. -�E01 nucleoli 1-2 �<

7

Size:- ��� ���������� 12-18 �����

Cytoplasm: - )NO8 ��P�0� ,�)*�+�,���A. -01 specific granules 3 P+� �L�:-Neutrophilic myelocyte-Eosinophilic myelocyte-Basophilic myelocyte

Nucleus:-���9�L��)- ����P+���1 9�L�����T��� - chromatin 9�1�A.- ����=�01 nucleoli

Eosinophilic myelocyte

Basophilic myelocyte

Neutrophilicmyelocyte

8

Size:- ��� ����������10-15 �����

Cytoplasm: - )NO8 ,�)*�+�,���A. -01 specific granules P+�:-Neutrophilic metamyelocyte-Eosinophilic metamyelocyte-Basophilic metamyelocyteNucleus:-����=�����)�=������*�-9�L�@<U=-nucleus ����=������+��AU�9AU���� nucleus V<.�9�� - chromatin 9�1���A.

Neutrophilicmetamyelocyte

Eosinophilicmetamyelocyte

Basophilic metamyelocyte

9

Size:- ��� ���������� 9-15 �����

Cytoplasm:-01 specific granules 3 P+� -Neutrophilic band form-Eosinophilic band form-Basophilic band form

Nucleus:-band shaped(��*��L����,U shape 9�L� S shape)-nucleus ����=���+ ½ ��� nucleus V<.�9�� -chromatin 9�1 )����

Neutrophilicband form

Eosinophilicband form

Basophilic band form

10

Size:- ��� ���������� 9-15 �����

Cytoplasm:- )NO8 -�)*�+�,���A.-01 specific granules 3 P+� - Neutrophil- Eosinophil- Basophil(granules �<�EDV<1 nucleus)

Nucleus:-�) 2 @A� 5 lobes-chromatin 9�1 )�����9K��E<1-<=�E �)P���=�����parachromatin

11

Myelocyte Metayelocyte Band form Segmented form

12

• Neutrophil �������� ���� ������ 1-8% ���������� X chromosome �������� “drumsticks” �������� �!� chromatin ��"�# �$%�������� nucleus ���&������$��&�'��