INTRODUCTION TO AUTOMOMIC PHARMACOLOGY: Part I: Why study autonomic pharmacology?

INTRODUCTION TO AUTOMOMIC PHARMACOLOGY:

Part I: Why study autonomic pharmacology?

Autonomic Pharmacologyis Rewarding!!

LOGICAL

CLINICALLYRELEVANT

+

Anatomical, Physiological &Neurobiological

Information

Predict Effects of Drugs

Mechanism of Drug Action

Autonomic Pharmacology is Logical

+

Drug A decreases activity of

organ Y

Autonomic Pharmacology is Logical

Drug A blocks receptors for

neurotransmitter X

Nerves to organ Y release neurotransmitter X,

and X increasesthe activity of organ Y

Autonomic Pharmacology is Clinically Relevant

Autonomic drugs are used for the

treatment of Angina

Autonomic drugs are used for the

treatment of Heart Failure

Autonomic drugs are used for thetreatment of

Alzheimer’s Disease

Autonomic drugs are used for the

treatment of High Blood Pressure

Autonomic drugs are used for thetreatment of

Benign Prostatic Hypertrophy

Autonomic drugs are used for the

treatment of Anaphylactic Shock

Autonomic drugs are used for the

treatment of Septic Shock

Autonomic drugs are used for the

treatment of Asthma