STATUS OF POTENCY REAGENTS AND CANDIDATE VACCINE STRAINS

STATUS OF POTENCY REAGENTS AND CANDIDATE

VACCINE STRAINS

Food And Drug Administration

Center For Biologics Evaluation And Research

POTENCY REAGENTS

Reagents Currently Available for:

•H1N1 -A/New Caledonia/20/99

•H3N2 -A/Panama/2007/99

•B -B/Yamanashi/166/98

Candidate Strains:

•If new strains are chosen, reagents will be available in May at the earliest.

INFLUENZA A (H1N1) STRAIN

Current vaccine: Reassortant Growth•A/New Caledonia/20/99 IVR-116 Mod/high yield

Candidate strains:•No new antigenically divergent strains

INFLUENZA A (H3N2) STRAIN

Current vaccine: Reassortant Growth•A/Panama/2007/99 Resvir-17 Mod/high

Candidate strains:•A/Ulan Ude/1/2000 X-143 Mod/high

INFLUENZA B STRAINS

Current vaccine strain: Growth

•B/Yamanashi/166/98 Moderate

Candidate strains:

•B/Johannesburg/5/99 Low

•B/Victoria/504/2000 Moderate

•B/Alaska/16/2000 Low