Hiv natural origin drugs

NATURAL TREATMENT FOR AIDS Presented by Vedasree Reddy.Police 10T21SO112 Under the Guidance of Mrs.SharadhaSrikanth M.Pharm

CONTENTS: Types What does AIDS means Definition of Immunodeficiency

Disorders Etiological Agent Structure of HIV Steps of progression Diagnosis List of Natural Drugs Immune Boosters New Discoveries and updates

IMMUNODEFICIENCYDISORDER:

Failure or deficiency of immune system which manifests by occurrence of repeated infections in individuals with immune deficiency diseases.

TYPES:

Primary _ Genetic or Developmental abnormalities of immune system

Ex:Reticular dysgenesis

Secondary – Acquired Supression of Immunesystem.

Ex:AIDS,Infections.

AIDS MEANS:

Acquired Immuno Deficiency Syndrome

An epidemic,transmissible retroviral disease caused by infection with HIV which leads to profound depression of cell mediated immunity.

ETIOLOGICAL AGENT:

HIV- Human Immuno Deficiency Virus.

2 forms:HIV-1HIV-2

A RNA retrovirus.

STRUCTURE OF HIV

STEPS OF PROGRESSION:

DIAGNOSIS:

1.For establising HIV infection:a.Antibody Test – ELISA Western blot

b.Direct Detection of HIV 2.Tests for Defects in Immunity 3.Tests for Detection of opportunistic

infections

NATURAL DRUGS

BITTERMELON LICORICE ECHINACEA CAT’S CLAW

BITTERMELON: FRIUTSOF MOMORDICACHARANTIA.FAMILY: CUCURBITACEAE.

MECHANISM:

Proteins-

MRK29, may inhibit the activity of HIV-1 reverse transcriptase, an enzyme involved in the replication of the HIV virus.

MAP30, which may have anti-HIV effects

and that may also improve the efficacy of other anti-viral drugs.

CONSIDERATIONS:

Short-term use of bitter melon is likely safe, but using it for more than three months may be unsafe.

Avoid in bleeding disorder

Pregnant or breastfeeding women.

Glucose-6-phosphate dehydrogenase deficiency people.

LICORICE: LICORICE ROOT  IS THE ROOT OF PLANT GLYCYRRHIZAGLABRA OF FAMILY LEGUMINOSAE.

MECHANISM :

Glycyrrhizin inhibits HIV replication by 1.Inhibiting a cellular

enzyme(Casein Kinase )

2.Inhibiting viral adsorption, i.e,binding to

the host cell to be infected .

CONSIDERATIONS:

Pseudoaldosteronism.

Pregnant or breastfeeding women should not take licorice.

Use of any licorice product is not recommended for longer than 4 - 6 weeks.

ECHINACEA: FLOWERING PLANT OF GENUS PURPUREA OF FAMILY ASTRACEAE.

MECHANISM:

Fat soluble Alkylamides of the flower provide Immunomodulatory effects which act by binding to cannabinoid receptors and thus inhibits tumour necrosis factor-α

CONSIDERATIONS:

One dose treatment is not effective.

Allergic reactions like asthma attack and leucopenia are seen.

Use along with hepatotoxic drugs is avoided.

Avoided in patients with autoimmune disorders

CAT’S CLAW: Climbing stems of Uncaria tomentosa of family Rubiaceae.

MECHANISM :

Quinovic acid has a property of

Pronounced enhancement effect on PHAGOCYTOSIS.

Increased production of T-lymphocytes.

CONSIDERATION:

Because of abortive effects, it is avoided in pregnant women.

Dizziness and Vomiting are seen.

IMMUNE BOOSTERS:

Aloe Vera Astragalus Ginkgo Ginger Garlic Olive leaf extract Calendula Green tea

NEW DISCOVERIES AND UPDATES

NATURE EXAMPLES

ALKALOIDS PAPAVERINE, NITIDINE

GLYCOSIDES ROSAMULTIN, ANDROGRAPHOLIDES

FLAVANOIDS MANGOSTIN, OLIVE LEAF EXTRACT

COUMARINS CALANOLIDE, SUKSDORFIN

POLYSACCHARIDES CARRAGEENAN, HEPARIN

PROTIENS CYNOVIRIN, TRICHOSANTHIN

TANNINS OENOTHEIN, GALLIC ACID

LIGNANS ARCTIGENIN

CONCLUSION:

The remedy for all is –

“PREVENTION IS BETTER THAN CURE”

This holds good particularly in case of AIDS as it is a

preventable disease.

Leading a healthy and educative lifestyle can do

better with respective AIDS.

Natural remedy need not be necessarily be a cure

but can be an alternative or more preferably a

preventive in the case of AIDS.