Large Animals and Translational BioMedical Research

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Large animals and translational biomedical research

Erik ShapiroOVPRGS Large Animal

Interdisciplinary Forum 2016

Biomedical imaging

Biomedical imaging

Tissue engineering/Transplants

http://www.google.com/url?sa=i&rct=j&q=&esrc=s&source=images&cd=&cad=rja&uact=8&ved=0ahUKEwiojc6WwbbKAhWlm4MKHaLVAJQQjRwIBw&url=http://www.pangeatoday.com/first-phase-of-asias-first-trachea-transplant-successful/&psig=AFQjCNEgFnkJx7K9jzRbutkE2mN_4w5aHg&ust=1453314644421463
http://www.google.com/url?sa=i&rct=j&q=&esrc=s&source=images&cd=&cad=rja&uact=8&ved=0ahUKEwikjqOlwbbKAhWhtIMKHTVWBzMQjRwIBw&url=http://www.cnn.com/2011/HEALTH/07/07/trachea.transplant/&psig=AFQjCNEgFnkJx7K9jzRbutkE2mN_4w5aHg&ust=1453314644421463

NSRRC:0016 GFP NT92

NSRRC:0029 Albumin (ALB) promoter driving Thymidine Kinase (TK1)

NSRRC:0035 RAG2 KO

Iowa State/Kansas State SCID PigArtemis gene mutation

Swine experiments

Pig models of human ovarian cancer

N=8 N=8

How to breed for meaningful cohorts of animals (NIH robustness!!)

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