Introduction to SciFinder - The Chemical Research Tool for Scientists

6/28/2010

An Introduction to SciFinderAn Introduction to SciFinder®®

The Chemical Research Tool for ScientistsThe Chemical Research Tool for Scientists

Yvonne PopeRegional Marketing ManagerCAS

2CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Today’s discussion

SciFinder

Provides access to the world’s authority for chemical information

Offers synthetic researchers answers to their reaction questions

Speeds discovery by providing a sophisticated suite of analysis and research tools

3CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

ACS Vision

Improving people’s lives through the transforming power of chemistry

CAS is a division of the American Chemical Society

4CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

CAS supports the mission of the ACS

ACS Mission

To advance the broader chemistry enterprise and its practitioners for the benefit of Earth and its people.

CAS Commitment

To support the ACS mission by providing secure access to high-quality, comprehensive chemical information.

5CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

CAS DatabasesCAS Databases

“Being able to rapidly search for important chemical information while an idea is fresh in your mind is almost priceless.

CAS databases streamline the investigative process –

allowing you to take an idea and rapidly find the important and necessary information before you forget about the idea or it loses its excitement.

That really is invaluable.”

Dr. Robert H. GrubbsNobel Laureate

Victor and Elizabeth Atkins Professor of ChemistryCalifornia Institute of Technology

6CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

CAS is the world leader in providing chemical information…

7CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Types of reactions in CASREACT

Single-step reactions–

Single-step multi-stage reactions

Multi-step reactions

Stereo-specific syntheses

Biologically mediated reactions

Prophetic reactions from patents

8CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Begin by using the drawing editor to draw a reaction

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Verify search type and limiters before submitting the search

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Note size of initial answer set and default sort option

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Get similar reactions to create a new answer set

12CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Sort reaction answers to display relevant reactions

13CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Limit a solvent before a search

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Limit by solvents using the Solvent Hierarchy

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Limit by solvents using the Solvent List

16CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Case Study: Patents involving Suzuki Cross- Coupling Chemistry

I am in interested in intellectual property pertaining to SuzukiCross-Coupling Chemistry

“Difficult” to solve through structure query in any reaction database!

Coverage of patents in reaction database is important

One solution is to search text information in a database that isdirectly linked to a reaction database

17CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Use SciFinder’s

Explore by Research Topic to solve this search problem

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Analyze references for patents to focus on IP in this area

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Analyze

patented Suzuki chemistry technology areas

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Determine which Suzuki reactions are reported in these patents

21CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Determine which Suzuki reactions are reported in these patents

NOTE: Some reactions from these patents are not Suzuki

22CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Isolate actual Suzuki reactions with the Refine tool

B

23CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Isolate actual Suzuki reactions with the Refine tool

B

24CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Use keyword searching to identify reactions with “difficult”

chemistry

Found more than 12,000 references mentioning Suzuki in the scientific literature

–

> 800 references from patents

Found > 2,000 reactions covered in these patents

Isolated > 100 actual Suzuki reactions for review

25CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

SciFinder is a valuable resource for locating reaction information

Timely – reactions are added each week

Flexible – reaction information is seamlessly integrated with reference and substance information

Comprehensive – reaction coverage has expanded by addition of older reactions at the same time editorial scientists keep up with current literature

26CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

SciFinder is the premier enterprise-wide research discovery tool

used by scientists around the world

27CAS is a division of the American Chemical Society. Copyright 2010 American Chemical Society. All rights reserved.

Questions