Ray-D Investment proposal Konev Vladimir, CIO, Engineering Center NRNU MEPhI

Relevance

12 mln.  Mortality rate from cancer per year1  

80%  Deterioration of existing

equipment2  

Every minute, is making one cancer diagnosis. To continuous growth of cancer diseases contributes the overall deterioration of the environmental situation, and a number of powerful man-made disasters such as accidents at the Fukushima-1

The high cost of foreign equipment, the complexity of its operation and the high requirements for the conditions of maintenance hinder to the regular update and replenishment of the park diagnostic instruments

7%  Satisfaction of demand on ray methods of examination and

treatment3  

The lack of the necessary equipment, the high cost of the survey become the cause of the lack of timely treatment, which is especially important for regional health facilities.

1 According to World Cancer Research Fund 2,3 According to Federal medical-biological Agency of Russia  

Problems of existing methods

Existing diagnostic methods don't allow with high accuracy to diagnose the scale of the disease

Disadvantages: •  Low accuracy •  The risk of recurrence •  Collateral damage for the patient's

health (healthy tissue is removed) •  Economic and organizational limits

Tomography  

Mammography  

Decision

Innovative tool for beam diagnostics of cancer tumors. Ray-D enables to determine exactly how deeply into the organism has penetrated the process of metastasis.

Ray-D  

Principle of operation

For recognition of the spread scale of the tumor necessary to find out which lymph nodes are affected by metastasises, and which - no

Special emitting radiopharmaceuticals can be accumulated in places of concentration of metastasis

Ray-D detects emission of radiopharmaceuticals, thus revealing lymph nodes affected by tumor

The affected lymph nodes  

Healthy lymph nodes  

1/ Preparing

2/ Diagnostics

3/ Analysis

Application

Diagnosis of cancer without surgery Ray-D enables without surgical intervention to detect shallowly located tumors. Breast cancer: •  Second place in all oncology •  Main reason of death among woman in oncology

Accurate detection of tumor borders Ray-D is an additional tool during operations to remove the cancer and enables with high accuracy to establish the limits of its distribution (to detect sentinel nodes).

Competitors

Manufacturer The spatial

resolution, mm Spatial selectivity, ° Sensitivity, p / s / kBq

Price

Ray-D (Russia, MEPhI)

8 26 10 ~4500$

EuroprobeCsJ, Eurorad (France)

14 35 10

~18000- 30000 $

C-Trak Omni-Probe, Care Wise

(USA) 15 50 23

Neoprobe 2000 (USA)

15 36 10

Market

$ 440 billions  World market volume of

medical equipment by 2018  

80%  The volume of state purchases of

the total volume of medical equipment market in Russia  

Diagnosis in the laboratory by 2018 will be the most advanced segment of of this industry, achieving sales volume of 54.5 billion dollars. According to research firm EvaluatePharma.

The growth of the market of diagnostic equipment in Russia is primarily associated with high investments in the sector by the government. According to the agency DISCOVERY Research Group

$ 31,6 billions The volume of the market of

equipment for beam diagnostics  

The volume of the market of equipment for beam diagnostics in 2011 has become on 30% higher than in 2010. The market growth in real terms was 87%. The share of imported vehicles on the Russian market, which could potentially be replaced by domestic counterparts is 67%

Commercialisation

Sale of finished complexes in medical centers, including through distributors of medical equipment  

- Electronic components - Costs of production : •  Production of PCB •  Mounting of components •  Case production •  Production of packaging •  Other services of contractors •  Assembly •  Control -  Expenses for marketing and

promotion -  Expenses for administrative staff -  Other expenses Profit

3300$

Product unit cost

Proposal

Р 22 mln.  Volume of required

investments in the project  

R&D

Running a trial lot

Rework

Preparation of production  

Product and production certification

Running of sales

Indicator Value

NPV, thousand rubles 48702

The discount rate, % 25,8

MIRR, % 23

PI 1,95 The discounted payback period,

months 39

Settlement period, years

5

20 %  he investor's share in the

company  

Road Map

2013

Developed a prototype of device   R&D  

Release of trial lot  

Rework

Preparation of production  

Certification of production  

Device certification  

Running of sales  

The project team

Dmitry Mikhailov Project director Ph.D., associate professor of NRNU "MEPhI". A member of the Russian Council of Young Scientists of the Russian Federation. The author of over 40 publications, two monographs and a textbook. Award winner for supporting talented young people, established by presidential decree.

СТО Habibullin Timur

CFO Sorokina Maria

Lead Engineer Yagnyukova Anastasia

Project experience •  Endoscopic complex Lilly •  Cardiosense •  BlackBeeTrack •  VisioSmart •  AviaShopper •  …

Project experience BlackBeeTrack Control system of storage conditions and transportation of medicines

Lily Endoscopic complex for diagnosis of gastrointestinal tract

Cardiosense The complex of informing about the occurrence of myocardial

Own factory Experimental electronic manufacturing in Moscow

Engineering Center NRNU MEPhI •  Focus over high-tech R&D •  140 employees •  16 projects in different fields of business •  5 branches around the world (from Chilie

to Singapore)