© 2016 MapR Technologies

Crystal Valentine, PhD VP of Technology Strategy

The Human Face of Big Data

© 2016 MapR Technologies

Human Welfare

India

1.3 billion residents 640,000 villages 22 official languages $40 billion per year on subsidies 40% leakage

Subsidies as % of Government Expenditure

0

2

4

6

8

10

12

14

16

18

20

2006 2007 2008 2009 2010 2011 2012 2013 2014 2015

Largest Biometric Database in the World

PEOPLE

20 BILLION BIOMETRICS

Massive NoSQL Database Application

1M registrations (Trillions of matches) / day 5 TB incremental data / day 100M+ authentications / day 200 ms response 0.0001 false positive rate Billion+ audit records per day

Always-on high availability

●  Mirroring and backup across DCs

●  Strong consistency for update and insert

DC #1 Gurgaon

DC #3 Bangalore

Regional Backup #2

Regional Backup #4

Broad Application Support through Open APIs

Enrollment Services (40k enrollment stations) Authentication Services Fraud detection frameworks Administrative Services Analytics and Reporting Services Logistics services Contact Center

Impact >1 billion Aadhaars issued 95% of adults in India 500K-700K new enrollees everyday 200 milliseconds to verify an ID 240 million bank accounts 122 million LPG consumers 113 million ration cards

© 2016 MapR Technologies

Cancer Genomics

Human Genome Sequencing

3 Billion base pairs 25,000 Genes Massively parallel WGS pipeline Sequence over 10k Gbp/week

Cancer: a complex disease

2012: •  14.1M new cases •  8.2M deaths

1 tumor ~ 100 billion cells Characterized by pathway disruption

Interaction Network

Vertices = genes Edges = interactions “pathway” = subnetwork

Finding Mutated Pathways Network G = (V,E)

Binary mutation matrix

Patie

nts

Genes

= mutated = not mutated

+ =

Connected subnetworks mutated in significant number

of patients

*TCGA (Nature, 2011 and NEJM, 2013)

Individualized Treatment

Clinical / Lab Genomic / Network Analysis

Lifestyle / Phenotypic /

Health sensors

Electronic Medical Records

Literature / Research

Collaboration + Innovation

Susan G. Komen Big Data for Breast Cancer (BD4BC) Initiative •  Pledged to reduce mortality rate 50% in next decade •  Partnerships in 50+ countries •  Extensive network of researchers, health care providers,

patient advocates, clinics •  Leverage shared/public data sets + big data technologies

© 2016 MapR Technologies

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